Clinical trials: HBP
Pulmonary Arterial Hypertension
A Study of Ranolazine Acute Administration and Short Term Administration in Pulmonary Arterial Hypertension
The purpose of this study is to assess the safety of ranolazine in people with pulmonary arterial hypertension (PAH) and who are receiving 1 or more background PAH therapies: ambrisentan, sildenafil,tadalafil, epoprostenol…
- Trial name
- NCT01757808
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Chicago
Arterial Hypertension, Cardiovascular Diseases
Telemedical Algorithm-Supported Care for Hypertension
Hypertension is a major global health issue, affecting around 9 million people in Poland. While some studies indicate that telemonitoring benefits patients with hypertension, there is a lack of research evaluating tools that…
- Trial name
- SOT-ART-HT (NCT06722625)
- Testing
- Evaluation of a blood pressure monitoring system with an integrated algorithm that supports the doctor's decision-making process
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Poznan University of Medical Sciences
Blood Pressure, High, Blood Sugar; High
Observe the Effect of Wheatgrass and Tulsi Formulation or Individuals Taken With Other Allopathic Drugs
Antioxidant qualities have been attributed to wheatgrass and tulsi formulation. Free radicals are unstable molecules created by the body during metabolism and exposure to environmental pollutants.
- Conditions
- Blood Pressure, High, Blood Sugar; High, Weight, Birth, Smoking
- Trial name
- NCT05851040
- Testing
- Observation study
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Swalife Biotech
Cardiovascular Risk Factor, Metabolic Syndrome
Dietary Intake of Whole Walnuts in Adult Subjects Under Low Cardiovascular Risk
This cross-over study investigates health effects of dietary intake of whole walnuts towards cardiovascular risk factors in adults under low cardiovascular risk.
- Conditions
- Cardiovascular Risk Factor, Metabolic Syndrome, Hypertension
- Trial name
- FitALA (NCT03227497)
- Testing
- Whole Walnuts
- Where
- Serbia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Glaucoma, Primary Open Angle
LSFG in Patients With Normal Tension Glaucoma Tension Glaucoma
Glaucoma is the second leading cause of blindness worldwide. Literature shows increasing evidence that dysfunction of ocular microcirculation in the optic nerve influences the progression of glaucoma.
- Trial name
- NCT03318510
- Testing
- Laser Speckle Flowgraphy
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Augenabteilung Allgemeines Krankenhaus Linz
Hypertension
Comparing Hypertension Remote Monitoring Evaluation Redesign
The goal of this clinical trial is to compare the effectiveness of evidence-based, adapted, and tailored, patient-focused and clinic-focused strategies to improve blood pressure (BP) control in English- and Spanish-speaking…
- Trial name
- CHARMED (NCT06113458)
- Testing
- Standard and One-time Training, Standard and Practice Facilitation, High-intensity and One-time Training
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pre-Eclampsia
Maternal Serum Stathmin-1 Levels in Preeclampsia
This study investigates maternal serum Stathmin-1 (STMN-1) levels in pregnancies complicated by preeclampsia and severe preeclampsia, compared to healthy pregnancies.
- Trial name
- NCT06623955
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Glaucoma, Ocular Hypertension
Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With Glaucoma
Glaucoma is the leading cause of irreversible blindness worldwide. Previous studies demonstrate that smaller eye drops used in the treatment of glaucoma are just as efficacious as their larger counterparts.
- Conditions
- Glaucoma, Ocular Hypertension, Open Angle Glaucoma
- Trial name
- NCT05273385
- Testing
- Nanodropper
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of California, San Francisco
Hypertension
High Dose BAYA1040_Nifedipine: a Long Term Combination Study
This is a clinical study evaluating the safety and efficacy of long term administration of oral BAYA1040_Nifedipine 80 mg/day (40 mg twice daily) with other antihypertensives in patients with essential hypertension who are not at…
- Trial name
- NCT01294215
- Testing
- Nifedipine (Adalat, BAYA1040)
- Where
- 4 sites in Japan
- Volunteers
- 72 people
- Sponsor
- Bayer
Open Angle Glaucoma, Ocular Hypertension
Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy
The aim of this study is to evaluate the efficacy of selective laser trabeculoplasty after a prior failed phacoemulsification and Eximer Laser Trabeculectomy.
- Conditions
- Open Angle Glaucoma, Ocular Hypertension, Cataract
- Trial name
- SLT (NCT02434250)
- Testing
- Selective Laser Trabeculoplasty
- Where
- Switzerland
- Volunteers
- 203 people
- Sponsor
- University of Zurich
Pseudotumor Cerebri
Pseudotumor Cerebri Headache Ten Years Outcome
Telephone interview on patient who suffered from PTC ten years ago regarding their headache status
- Trial name
- NCT06581185
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
High Altitude Pulmonary Hypertension
Highlanders With High Altitude Pulmonary Hypertension (HAPH), 6 Minute Walk Distance (6MWD) Assessed at 3200m With and Without Supplemental Oxygen Therapy (SOT)
The investigators aim to study the effect of SOT in highlanders with high altitude pulmonary hypertension (HAPH) who permanently live >2500m on 6-minute walk distance (6MWD) assessed at 3200m.
- Trial name
- NCT06489743
- Testing
- 6-minute walk test (6MWT)
- Where
- Kyrgyzstan
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Angle Closure Glaucoma
Evaluation of Clinical Decisions and Assessment of Those at Risk of Primary Angle Closure by Community Optometrists
Increases in the aging population has resulted in increased demand for glaucoma services. Glaucoma is a disease that if untreated, can lead to blindness.
- Trial name
- NCT05543889
- Testing
- Educational package
- Where
- United Kingdom
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Adverse Pregnancy Outcome
Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project
The goal of this randomized clinical trial is to evaluate if we can use placental pathology in a prior pregnancy which had an adverse outcome, such as early delivery, stillbirth, a baby born smaller than expected, or severe forms…
- Trial name
- NCT06004674
- Testing
- Lovenox 40mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Endeavor Health
Hypertension
The Effect of a Complementary Multi Disciplinary Program on Blood Pressure in Hypertensive Patients
Intervention description: Complementary Approaches to Lower Mean arterial pressure (CALM) is a multi dispensary program aimed to reduce blood pressure in hypertensive patients.
- Trial name
- NCT00409149
- Testing
- CALM Approache, DASH approach
- Where
- Israel
- Volunteers
- 113 people
- Sponsor
- Assaf-Harofeh Medical Center
Angle Closure Glaucoma, Glaucoma
Short-term Outcomes of Iridoplasty for Persistent Angle Closure Despite Patent Iridotomies
Purpose: To evaluate short-term angle opening after argon peripheral iridoplasty using AS-OCT and to report its complications at 1-week and 1-month follow up in patients that did not achieve a satisfactory clinical angle opening…
- Trial name
- ALPIECA (NCT02199158)
- Testing
- Argon Laser Peripheral Iridoplasty
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Cirrhosis
"Anticipant"-TIPS After a First Portal-hypertension-related Complication in Cirrhosis
Further decompensation (FD) in cirrhosis represents a prognostic stage associated with an even higher mortality than that associated with the first decompensation.
- Trial name
- Ant-TIPS (NCT07889726)
- Testing
- TIPS, Standard of Care (SOC)
- Where
- 8 sites in France
- Volunteers
- 266 people
- Sponsor
- University Hospital, Toulouse
Severe Preeclampsia
Comparative Study of Intravenous Labetalol Versus Intravenous Nitroglycerin Versus Sublingual Nifedipine
Pre-eclampsia (PE) is one of the most frequent pregnancy complications and is one of the main causes of maternal and fetal morbidity and mortality in its severe form.control of blood pressure is of crucial importance to avoid…
- Trial name
- NCT06265415
- Testing
- Labetalol, Nitroglycerine, Nifedipine
- Volunteers
- 60 people
- Sponsor
- Sohag University
Pulmonary Arterial Hypertension
An Open Label Extension Study to Evaluate the Safety of Continued Therapy of Subcutanous Remodulin® in Pulmonary Arterial Hypertension
This is a multicenter, open-label trial to evaluate the safety of continued therapy with subcutaneous Remodulin® in subjects with pulmonary arterial hypertension (PAH) who complete the CVT-CV-003 study.
- Trial name
- NCT02882126
- Testing
- Subcutaneous Treprostinil
- Where
- 10 sites in China
- Sponsor
- United Therapeutics
Intra-Abdominal Hypertension, Abdominal Compartment Syndrome
Intra-abdominal Hypertension in Critically Ill Patients
The aim of the proposed study is to determine the incidence and prevalence of intra-abdominal hypertension and abdominal compartment syndrome in consecutive intensive care admissions using broad inclusion criteria.
- Trial name
- NCT02514135
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 286 people
- Sponsor
- Western University, Canada
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