Clinical trials: HEALTHY INDIVIDUALS
Inflammation
Evaluate the Effects of a Marine Lipid Oil Concentrate Formulation on Inflammation/Discomfort
The purpose of the study is to assess the efficacy and safety of a Marine Lipid Oil Concentrate formulation on inflammation/discomfort and overall well-being in male and female subjects who are generally healthy
- Trial name
- NCT04819646
- Testing
- Marine Lipid Oil Concentrate Formulation, Dietary Supplement
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Digestive Health, Metabolic Health
Investigating the Tolerability of Oat Fiber (BG-OS) in Healthy Individuals
The goal of this interventional study is to evaluate the tolerability and potential health benefits of oat fiber oligosaccharide (BG-OS) in healthy adults aged 18-70 years.
- Trial name
- NCT06739941
- Testing
- Oat fiber (BG-OS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- One Bio Inc.
Sars-CoV-2 Infection
Safety, Tolerability and Immunogenicity of Alveavax-v1.2, a BA.2/Omicron-optimized, DNA Vaccine for COVID-19 Prevention
The investigated product is a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Booster Vaccine candidate optimized for the Omicron/BA.2 variant.
- Trial name
- NCT05844202
- Testing
- Alveavax-v1.2, Janssen Ad26.COV2.S
- Where
- 8 sites in South Africa
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Alvea Holdings, LLC
Healthy, Bronchiectasis
A Pilot Study to Investigate Administration of Mannitol Via a Novel Dry Powder Inhaler Device
A novel dry powder inhaler device will be used to administer mannitol to healthy subjects and subjects with bronchiectasis in single doses higher than previously given.The main objective is to assess tolerability of these doses…
- Trial name
- NCT00730977
- Testing
- dry powder inhaled mannitol
- Where
- Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Syntara
Age-related Cognitive Decline
Effect of Transcranial NIR Light Upon Memory
A double-blind placebo-controlled study evaluating the effect of 1068nm NIR trans-cranial phototherapy upon the cognitive function of healthy individuals between the age of 45 years and 80 years.
- Trial name
- NCT04568057
- Testing
- NIR Transcranial phototherapy device
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Maculume Ltd.
Cognition
Motivation, Brain Function and Mood in Individuals With Cold and/or Flu
This study aim to adapt and test a novel indication of motivation in participants with cold \& flu using the Picture Surfing Task (PST).
- Trial name
- NCT02860169
- Testing
- Participants self-administered questionnaire and assessment
- Where
- United Kingdom
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetes
A Prospective Collection of Peripheral Blood and Urine Specimens to Study C-peptide and Insulin in Healthy Individuals
The study objectives are described below: 1. Obtain matched serum, plasma [(K2 EDTA, Sodium Heparin (NaH), Lithium Heparin (LiH)] and urine specimens collected from a minimum of 50 healthy subjects.
- Trial name
- NCT02614170
- Testing
- Prospective Blood Draw
- Where
- United States
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Fujirebio Diagnostics, Inc.
Healthy
Healthy Volunteer Study to Assess Microcirculatory Function
The aim of the study is to obtain microvascular data from a healthy, heterogeneous population for assessing reference values for the parameters Functional Capillary Density (FCD), heterogeneity of FCD, Microvascular Oxygen…
- Trial name
- NCT05608798
- Testing
- ODI-Tech medical device
- Where
- Norway
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- ODI Medical AS
Irritable Bowel Syndrome, IBS - Irritable Bowel Syndrome
Human Milk Oligosaccharides (HMOs) for Irritable Bowel Syndrome (IBS)
To assess the effects of a Human Milk Oligosaccharide mix given once daily for 12 weeks on stool consistency and abdominal pain compared to placebo in individuals with Irritable Bowel Syndrome (IBS).
- Trial name
- HIBS (NCT05205785)
- Testing
- Human Milk Oligosaccharide Mix
- Where
- Ireland
- Volunteers
- 204 people
- Sponsor
- dsm-firmenich Switzerland AG
Influenza
Safety Study of Live Attenuated Influenza Vaccine, CodaVax, Delivered Via Intranasal Spray
This study is being conducted to assess the safety, tolerability, and immunogenicity of the live-attenuated CodaVax-H1N1 influenza vaccine as compared to normal saline placebo both administered via intranasal spray to healthy…
- Trial name
- NCT04146623
- Testing
- CodaVax-H1N1 influenza vaccine
- Where
- Australia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Codagenix, Inc
Healthy Female Adults
A Study of Navlimetostat (BMS-986504) Drug Interactions and Food Effect in Healthy Participants
The purpose of this study is to assess the food effect and drug interactions on drug levels of Navlimetostat in health adult female participants
- Trial name
- NCT07800897
- Testing
- Navlimetostat, Itraconazole, Rifampin
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Biomedical Enhancement
The Effects of a Combination of Nootropic Ingredients on Cognition in Healthy Young Volunteers
Achieving optimal concentration during cognitively demanding tasks is of immense human value. Despite our understanding of the important role that attention, working memory, and fluid intelligence play in professional success…
- Trial name
- NCT02857829
- Testing
- CAF+, Caffeine-alone
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Nootrobox, Inc.
Rabies (Healthy Volunteers)
Immunogenicity and Safety Assessment of Rabies Vaccine (Vero Cell) for Human Use, Freeze-dried
To evaluate the immunogenicity and safety of different post-exposure prophylaxis (PEP) schedules of Sinovac rabies vaccine, in comparison with a marked rabies vaccinein china, in subjects aged 10-60 years old.
- Trial name
- NCT07357545
- Testing
- Sinovac rabies vaccine, Marketed rabies vaccine
- Where
- 2 sites in China
- Volunteers
- 2,040 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Treponema Pallidum, Treponema Pallidum Infection
This Study Evaluates the ALPCO Syphilis-T and Syphilis-NT CLIA Kits for Detecting Syphilis Antibodies in Serum and Plasma. Samples From At-risk, HIV-positive, Pregnant, and Healthy Individuals Will Assess Assay Performance Versus Established Comparator Tests.
This study will evaluate the clinical performance of two investigational diagnostic kits developed by ALPCO: the Syphilis-T CLIA Kit and the Syphilis-NT CLIA Kit.
- Conditions
- Treponema Pallidum, Treponema Pallidum Infection, Syphilis Infection, Serum
- Trial name
- NCT07089836
- Testing
- ALPCO Syphilis-T, ALPCO Syphilis-NT CLIA Kits
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- American Laboratory Products Company
Healthy
Observational Metabolic Health Study
The rationale for this study is to observe the effect of a consumer-grade commercially available product called Mimio Biomimetic Cell Care on metabolic health in overweight individuals.
- Trial name
- NCT06790407
- Testing
- Mimio Study Product
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mimio Health, Inc.
Healthy Participants
A Phase 1 Study of Navlimetostat Tablet Formulations
This study aims to compare the PK of Navlimetostat after administration of a wet-granulation tablet versus the dry-granulation tablet formulation in healthy adult female
- Trial name
- NCT07544628
- Testing
- Navlimetostat
- Where
- 4 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
SARS-CoV-2 Infection, COVID-19
A Study to Learn About New COVID-19 RNA Vaccine Candidates in COVID-19 Vaccine-Experienced Healthy Individuals
The purpose of this clinical trial is to learn about the safety, tolerability and immunogenicity of BNT162b RNA-based SARS-CoV-2 vaccine candidates in adults to prevent COVID-19.
- Trial name
- NCT05472038
- Testing
- BNT162b5 Bivalent (WT/OMI BA.2), BNT162b2 Bivalent (WT/OMI BA.1), BNT162b2 Bivalent (WT/OMI BA.4/BA.5)
- Where
- 31 sites in United States
- Volunteers
- 1,453 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Detection of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 in Individuals Exposed to SARS-CoV-2
Assessment of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 Peptide Antigens
This dose finding, multi-cohort study is designed to evaluate the safety and efficacy of intradermally-injectedTNX-2100, synthesized SARS-CoV-2 peptide antigens and assess the presence and magnitude of DTH reactions.
- Trial name
- COVID-19 DTH (NCT05216510)
- Testing
- TNX-2110, TNX-2120, TNX-2130
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Tonix Pharmaceuticals, Inc.
Healthy, Asymptomatic
Normal Values of High Frequency ECG (HyperQ™) in Apparently Healthy Individuals and in Young and Masters Athletes
The main objective of this study is to investigate depolarization characteristics represented by changes in HyperQ in asymptomatic, apparently healthy athletic and non-athletic individuals.
- Conditions
- Healthy, Asymptomatic, Obesity
- Trial name
- NCT00847353
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- BSP Biological Signal Processing Ltd.
Metabolic Syndrome
Investigation of Metabolomics Differences Between Metabolic Syndrome and Healthy Individuals in Taiwan
The prevalence of metabolic syndrome in Taiwan has been increasing yearly. In this project, the database of blood test results from healthy and metabolic syndromes individuals will be analyzed to identify the small molecules…
- Trial name
- NCT06363864
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Leeuwenhoek Laboratories Co. Ltd.