Clinical trials: HEALTHY INDIVIDUALS
Healthy
Effects of Sage Extracts on Cognitive Function During Aerobic Exercise
Extracts of sage have been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has clearly demonstrated the possible effects in healthy individuals in…
- Trial name
- NCT04804657
- Testing
- Sage extracts Cognivia
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Burgundy
Overweight/Obesity (BMI: 27 and 35 kg/m2)
tVNS and Obesity-related Mechanisms
The overarching goal of the project is to assess whether transcutaneous Vagus Nerve Stimulation (tVNS) induced reduction of central and peripheral inflammation is associated with tVNS induced changes in mood and motivation in a…
- Trial name
- NCT06954844
- Testing
- Transcutaneous non-invasive vagus nerve stimulation (tVNS), Low intensity stimulation
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Investigating Spinal Atrophy in Patients With Spinal Injury
Plasticity of Grey and White Matter in Response to Motor Skill Training in Healthy Individuals and Those With Spinal Cord Injury
We aim to investigate the effect of motor skill training of the upper and lower limbs on the function and structure of the CNS as measured by neuroimaging parameters sensitive to changes in tissue volume and density and the…
- Trial name
- NCT02148887
- Where
- Switzerland
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Trigger Point Pain, Myofascial
The Effect of Dry Needling on Muscle Stiffness, Gait, Motion, and Strength in Healthy Individuals With Trigger Points
This study would be the first study to assess the immediate effects of dry needling of latent trigger points of the gastrocnemius muscle on muscle stiffness, gait, range of motion, and strength.
- Trial name
- NCT03689283
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Regis University
Arterial Stiffness, Blood Pressure
Korean Red Ginseng Rg3 Extract on Arterial Stiffness and Blood Pressure
The purpose of the study is to evaluate the acute effect of a standardized extract of KRG (Rg3-KRG) consisting of 30% total ginsenosides, including 10% Rg3 ginsenoside on arterial stiffness and blood pressure, as measured by the…
- Trial name
- KRAB (NCT01951443)
- Testing
- Ginseng, Wheat Bran
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Cell Function
In Vitro Study of Peripheral Blood Mononuclear Cell Function in Healthy Individuals and Patients
Peripheral blood mononuclear cells (PBMC) will be collected from healthy volunteers and patients who present with different diseases that involve or implicate the immune system dysregulation (HIV infection, autoimmune diseases…
- Trial name
- NCT00342485
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Aging
The Bioavailability of Compounded and Generic Rapamycin in Normative Aging Individuals
This study collected real-world evidence to better understand and define the relative bioavailability ratio between compounded rapamycin and generic rapamycin, with a specific focus on relative efficacy in increasing rapamycin…
- Trial name
- NCT06550271
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- AgelessRx
Healthy, Physical Activity
Physiological and Psychological Effects of Virtual Reality vs Traditional Exercise
This study aimed to explore the feasibility and effectiveness of immersive Virtual Reality (VR) as an alternative to traditional High-Intensity Interval Training (HIIT) by comparing physiological and psychological outcomes in…
- Conditions
- Healthy, Physical Activity, Virtual Reality, Exergame
- Trial name
- NCT06420414
- Testing
- Virtual Reality, Traditional HIIT
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Teesside University
Healthy Individuals
Effects of BLa80 and LRa05 on the Gut Microbiota Metabolite Profile of Healthy Individuals
Gut microbiota play a key role in polyphenol metabolism, participating in the breakdown of dietary components and producing various small molecule metabolites that affect human health.
- Trial name
- NCT07287306
- Testing
- BLa80, LRa05
- Where
- China
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Proprioception
Evaluation of Joint Position Sense in Healthy Individuals
It was aimed to measure the elbow joint position sense in healthy individuals in the case of a closed kinetic chain and to compare it with the measurement made in the case of an open kinetic chain.
- Trial name
- NCT06276920
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Inonu University
Aberration, Corneal Wavefront
Immediate Effects of Lipid-Based and Non-Lipid Artificial Tears on Corneal Aberrations
This study evaluates the immediate effects of two types of artificial tear formulations on corneal aberrations in a healthy population.
- Trial name
- ILEACT (NCT06784661)
- Testing
- Lipid-Based Artificial Tear, Non-Lipid Artificial Tear
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Seville
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Comparison of Alveolar Macrophages in Healthy Individuals Versus Individuals With COPD
This study group forms the normal subject control group in an experiment designed to determine whether the alveolar macrophages (AMø) of patients with chronic obstructive pulmonary disease (COPD) show abnormal responsiveness to…
- Trial name
- NCT00281203
- Testing
- blood drawing, fiberoptic bronchoscopy
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy
The Effects of Dark Chocolate (70% Cacao) on EEG Brain Waves in Vigorously Active Individuals
The purpose of this graduate student study is to determine if ingestion of dark chocolate (70% cacao) will change brain frequencies between visualization at a state of rest and a state of exercise performance via…
- Trial name
- NCT03203824
- Testing
- dark chocolate, non dark chocolate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Healthy Volunteers From Racial/Ethnic Minority Populations
EXPLORER PET/CT: Evaluation of Healthy Individuals From Racial/Ethnic Minority Populations
The objective of this pilot study is to collect preliminary data using total body scans on a new, first of its kind, FDA 510k-cleared positron emission tomography/computed tomography (PET/CT) scanner, called EXPLORER.
- Trial name
- NCT04812080
- Testing
- EXPLORER PET/CT
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Anxiety, Depression
The Effects of Virtual Reality Education on Balance, Depression, Anxiety and Stress Parameters
If we examine the demographic data of the 2021 reports of the Turkish Statistical Institute (TUIK), we can see that the young population between the ages of 15 and 24 is 12,971,289 people, which is 15.3% of the total population.
- Conditions
- Anxiety, Depression, Stress, Balanced
- Trial name
- NCT05985096
- Testing
- Virtual reality group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ordu University
Healthy
Exploring the Relationship Between Social Expertise and Ability to Process Different Types of Abstract Concepts and the Neural Resources Allocated to Their Processing
Social interaction is supported by several brain regions, which are involved in encoding socio-perceptual information, attributing affective and mental states to other conspecifics, and ultimately enabling the orchestration of an…
- Trial name
- EXPERTISE-SOC (NCT07112027)
- Testing
- Behavioral and MR scanning
- Where
- Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Tuberculosis
A Clinical Study of the HCMV-TB Vaccine Candidate VIR-1778 in Healthy Adults
This Phase 1, randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability, and immune responses of the investigational HCMV-TB vaccine candidate VIR-1778 in adults in overall good health without HIV…
- Trial name
- NCT07818824
- Testing
- VIR-1778 (5 × 10^5 ffu), VIR-1778 (5 × 10^6 ffu)
- Where
- 2 sites in Peru
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Autoantibodies, Interleukin-6
Characterization of Natural IL-6 Inhibition in Healthy Individuals
The aim of the project is to investigate whether or not there are any difference in cardiometabolic outcomes in individuals with high or low levels of c-aAb against interleukin-6 (IL-6).
- Trial name
- FIDI (NCT05867524)
- Testing
- Oral Glucose Tolerance Test, Cycling test
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy Individuals
Effects of Nervous System Mobilization
This study aims to compare the effect of tension neural mobilization versus sliding neural mobilization of the peroneal nerve on the heat and cold threshold, on pressure pain threshold and on flexibility both in the dominant…
- Trial name
- NCT03029260
- Testing
- Neural mobilization - tension., Neural mobilization - gliding
- Where
- Portugal
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Low Back Pain, Respiratory Loading
Inspiratory Resistive Loading and Proprioceptive Postural Control
Proprioceptive weighting changes may explain differences in postural control performance. In addition, the respiratory movement has a disturbing effect on postural balance.
- Conditions
- Low Back Pain, Respiratory Loading, Proprioceptive Impairment
- Trial name
- NCT01541020
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven