Clinical trials: HEALTHY INDIVIDUALS
Healthy Aging
The Efficacy and Tolerability of Canagliflozin in Healthy Individual
The primary objective is to measure the effects that canagliflozin intervention has on reducing average glucose in healthy individuals.
- Trial name
- NCT06301529
- Testing
- Invokana Pill
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AgelessRx
Healthy Men
Time-Dependent Mobilization of Circulating Progenitor Cells During Strenuous Exercise in Healthy Individuals
Only few data are available on the influence of strenuous exercise on the content of circulating progenitor cells and especially the timeframe of their release.
- Trial name
- NCT00900107
- Testing
- Exercise
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Type2 Diabetes
Anatomical and Physiological Characterisation of the Gut Endocrine Cells in Healthy and in Patients With Type 2 Diabetes
Investigation of the anatomical distribution of enteroendocrine cells by a systematic approach along the entire human intestinal tract in healthy individuals and patients with type 2 diabetes.
- Trial name
- NCT03044860
- Testing
- Double-balloon enteroscopy (DBE) with biopsy retrieval
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Healthy, Dysautonomia
Effects of Osteopathic Technique on Autonomic Nervous System Activity
Cranial osteopathic manipulation technique for brain and cranial nerve function, known as the fourth ventricle compression (CV4), has been recognized.
- Trial name
- Osteo (NCT06554834)
- Testing
- CV4 + RR, CV4, EEG/HRV/RSA (Electroencephalography, Heart Rate Variability, Respiratory Sinus Arrhythmia) Monitoring using Infiniti System
- Where
- Poland
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- SomaticMed
Health Adult Subjects
Impact of a Wheat-based Fermented Beverage on Microbiota and Metabolic Health in Healthy Individuals
The proposed study aims to evaluate the impact on intestinal and oral microbiota composition and the metabolic effects of the daily consumption of a wheat-based fermented beverage, developed under the collaborative WHEATBIOME…
- Trial name
- NCT07560527
- Testing
- Wheat-based fermented beverage
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Inflammation
Evaluate the Effects of a Marine Lipid Oil Concentrate Formulation on Inflammation/Discomfort
The purpose of the study is to assess the efficacy and safety of a Marine Lipid Oil Concentrate formulation on inflammation/discomfort and overall well-being in male and female subjects who are generally healthy
- Trial name
- NCT04819646
- Testing
- Marine Lipid Oil Concentrate Formulation, Dietary Supplement
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Depression, Stress
Effects of Landscapes on the Brain
There is an established consensus between researchers that the contact with natural environments has beneficial influence on mental health and well-being of people exposed to them.
- Conditions
- Depression, Stress, Anxiety Disorders
- Trial name
- NCT04210856
- Testing
- Contemplative landscape exposure
- Where
- Singapore
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Healthy
Investigation of the Genetic and Environmental Determinants of MP Including Response to Supplementation
This study aims to investigate genetic and environmental determinants of macular pigment (MP) and assess the effects of lutein and zeaxanthin-rich supplements on macular pigment levels.
- Trial name
- NCT01778231
- Testing
- Nutrof Total
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Healthy Individuals
Bioavailability of Vitamin D Encapsulated in Casein Micelles, Compared to Its Bioavailability in the Milk-fat, or in a Synthetic Emulsifier Currently Used for Supplementation and Enrichment
The encapsulation within CM may improve bioavailability (BA) of vitamin D (VD), even in absence of fat. As a model the investigators have chosen nonfat yoghurt.
- Trial name
- NCT01259570
- Testing
- Group 1, Group 2, group 3
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Thinness, Health Behavior
Phenotypic Characteristics of Superlean Individuals Including Gut Microbiome
The goal of this observational study is to build on our previous work to further characterise the phenotype of superlean individuals (BMI < 18.5) when compared to normal BMI people (BMI 21.5 to 25).
- Trial name
- NCT05804929
- Testing
- Observation without intervention
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Acne Cystic, Diet, Healthy
Effect of Different Diets on Isotretinoin Users to Serum Lipid Levels
This research was planned to prevent secondary hyperlipidemia, which may occur due to isotretinoin used in the treatment of severe acne, with diet. There will be three different groups and followed for 12 weeks.
- Trial name
- NCT06250673
- Testing
- Diet experiment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Igdir University
Healthy Individuals, Highly Stressed
Could Meditation Modulate the Neurobiology of Learning Not to Fear?
It is well-established that the practice of mindfulness meditation leads to improvements in mental health and well-being and the cultivation of positive emotions.
- Trial name
- NCT01320969
- Testing
- Mindfulness-Based Stress Reduction course
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Digestive Health, Metabolic Health
Investigating the Tolerability of Oat Fiber (BG-OS) in Healthy Individuals
The goal of this interventional study is to evaluate the tolerability and potential health benefits of oat fiber oligosaccharide (BG-OS) in healthy adults aged 18-70 years.
- Trial name
- NCT06739941
- Testing
- Oat fiber (BG-OS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- One Bio Inc.
Obesity, Normal Weigth
Comparative Analysis of Postprandial Effects in Healthy and Obese Individuals
After eating, blood composition changes, including increased triglycerides and glucose, which can trigger postprandial inflammation. Particularly with high-fat foods, pro-inflammatory lipopolysaccharide (LPS) increases.
- Trial name
- CAPE (NCT06645756)
- Testing
- Test meal
- Where
- Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Foam Roller, Achilles Tendon
Effects of Foam Rolling on the Plantar Flexors' Properties
Self-massage is a set of therapeutic techniques performed by the individual using instruments such as a foam roller (i.e., foam rolling [FR]).
- Trial name
- NCT05801302
- Testing
- Foam rolling (shorter volume), Foam rolling (longer volume)
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Sars-CoV-2 Infection
Safety, Tolerability and Immunogenicity of Alveavax-v1.2, a BA.2/Omicron-optimized, DNA Vaccine for COVID-19 Prevention
The investigated product is a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Booster Vaccine candidate optimized for the Omicron/BA.2 variant.
- Trial name
- NCT05844202
- Testing
- Alveavax-v1.2, Janssen Ad26.COV2.S
- Where
- 8 sites in South Africa
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Alvea Holdings, LLC
Frailty
Safety, Efficacy of FFP From Healthy Donors to Ameliorate Frailty and Enhance Immune Function in Older Individuals
1. Primary Objective To determine the safety and tolerability of 12 once monthly transfusions of GMFFP (Granulocyte - Colony Stimulating Factor (G-CSF) Mobilized Fresh Frozen Plasma harvested from young, healthy donors), given to…
- Trial name
- NCT03458429
- Testing
- GMFFP
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dipnarine Maharaj
Healthy Individuals
Making Meals With Pulses
The goal for this study is to determine how Americans use beans, peas, and lentils (also called pulses) as part of a meal. The researchers will investigate food choices when getting a meal or dish ready that is made of more than…
- Trial name
- NCT07451119
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Crohn's Disease, Genetic Predisposition
Abnormal Fecal Microbiota in Healthy Subjects at High Risk for Crohn's Disease
Transversal multicentric French study on the microbiota in patients with Crohn's disease and their first degree healthy relatives The primary objective is the comparison of microbiota between patients with CD, healthy controls…
- Trial name
- MAGIC (NCT02826330)
- Testing
- biomarkers
- Where
- 10 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Alzheimer's Disease (AD)
The Cognitive Effects of Lorazepam in Healthy Older Individuals With TOMM40 Variable-length Polymorphisms
The investigators' goal is to determine if certain tests of memory and attention, performed while sleepiness is induced by a single dose of lorazepam, can predict whether or not an individual is at risk for developing Alzheimer's…
- Trial name
- NCT01780519
- Testing
- lorazepam
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic