Clinical trials: HEALTHY INDIVIDUALS
Healthy
The Effect of Aging and Immobilisation on Muscle
The debilitating effects of immobilisation on muscle strength and size in young individuals are well documented. Moreover, sarcopenia has long been recognized as a major cause of muscle strength loss in old age, however, changes…
- Trial name
- NCT00559806
- Testing
- 2 weeks of unilateral immobilisation and 4 weeks of resistance training
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Dental Implants, Single-Tooth
The Effect of Different Shapes of Interdental Brushes in the Management of Peri-implant Mucositis and Gingivitis
Rehabilitation of edentulous spaces with dental implants has become a routine treatment option as implants enjoy high survival rates over time.
- Trial name
- NCT03575858
- Testing
- Barrel shaped interdental brush, Tapered interdental brush
- Sponsor
- National University Health System, Singapore
Rotator Cuff Tears, Posture
Alterations in Spinal Alignment and Mobility in Individuals With Arthroscopic Rotator Cuff Repair
The aim of this observational study was to the alterations in spinal alignment in individuals who have undergone RC surgery and revealed the differences compared to healthy individuals.
- Conditions
- Rotator Cuff Tears, Posture, Spinal Curvatures, Arthroscopic Surgery
- Trial name
- NCT05721547
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Abant Izzet Baysal University
Periodontal Diseases, Diabetes Mellitus
Anti Oxidant Enzymes and Total Antioxidant Levels in Diabetes Mellitus Type II Patients and Healthy Individuals With Periodontitis
To evaluate the role of antioxidants - superoxide dismutase, catalase, glutathione and total anti oxidant levels in the serum of chronic periodontitis patients and chronic periodontitis with DM Type II patients, then to compare…
- Conditions
- Periodontal Diseases, Diabetes Mellitus, Enzyme Disorder
- Trial name
- NCT04180332
- Testing
- Blood sample
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ajman University
Medium-chain Acyl-CoA Dehydrogenase Deficiency
Metabolic Effects of Medium-Chain Fatty Acids in Patients With Medium-Chain Acyl-CoA Dehydrogenase Deficiency and Healthy Individuals
The aim of this project is to investigate the physiological effects of intake of long-chain fatty acids (LCFA) and medium-chain fatty acids (MCFA) in patients with Medium-Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) and…
- Trial name
- MEMCADD (NCT06623032)
- Testing
- Medium-Chain Fatty Acid (MCFA), Long-Chain Fatty Acid (LCFA)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy Volunteers, Heart Failure
A Research Study on the Effects of NNC0537-1482 in Healthy Individuals When Injected Under the Skin
The study is testing a new medicine to potentially treat people with heart failure. The main purpose of the study is to see if the new study medicine is safe and how it works in the body.
- Trial name
- NCT06625307
- Testing
- NNC0537-1482
- Where
- Netherlands
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Precancerous Condition
Sulindac in Preventing Melanoma in Healthy Participants Who Are at Increased Risk of Melanoma
This randomized phase II trial is studying how well sulindac works in preventing melanoma in healthy participants who are at increased risk of melanoma.
- Trial name
- NCT00841204
- Testing
- sulindac, laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Stroke, Multiple Sclerosis
Motor Skill Acquisition Between Individuals With Neurological Disorders and Healthy Individuals
Stroke survivors frequently show persistent gait deficits in their chronic stages even after years of intensive rehabilitation. This may be caused by diminished capability of re-acquiring motor skills post stroke.
- Trial name
- NCT04503187
- Testing
- Visuomotor leg reaching task
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Texas Woman's University
Dyslipidemia
The Effect of 3-Week Consumption of Soya Beverage Enriched With Plant Sterols on Serum LDL-C
This is a local, single-center, two-arm, randomized, double-blind, placebo-controlled clinical trial that examines the LDL-C-lowering effect of the consumption of a soya beverage enriched with plant sterol for 3 weeks.
- Trial name
- NCT02881658
- Testing
- Plant sterols-enriched soya beverage provided by Vitasoy, Soya beverage provided by Vitasoy
- Where
- Hong Kong
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Vibration; Exposure, Muscle Strength
Vibration Training in Healthy Individuals
The aim of the study was to examine the effect of six-week constant, low frequency and low amplitude Whole Body Vibration training on the strength and mechanical properties of the lower limb knee extensors and ankle joint dorsi…
- Conditions
- Vibration; Exposure, Muscle Strength, Lower Limb
- Trial name
- MusMechPro (NCT04738916)
- Testing
- Whole-body vibration training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Okan University
Instrument-assisted Soft Tissue Mobilization, Flexibility
Investigation of the Effect of Instrument Assisted Soft Tissue Mobilization Technique on Fascia and Fat Tissue Thickness in Healthy Individuals.
Instrument-assisted soft tissue mobilization (IASTM) technique can be used for non-pathological conditions as it has been shown in previous literature to affect flexibility and normal range of motion.
- Conditions
- Instrument-assisted Soft Tissue Mobilization, Flexibility, Fascia, Rehabilitation
- Trial name
- NCT05502497
- Testing
- Observational, IASTM Technique Application
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Inonu University
Caffeine
Effects Of Caffeine On Cognitive Performance
Caffeine is a potent central nervous system stimulant that increases the activity in the prefrontal cortex and can improve cognitive skills.
- Trial name
- NCT05995314
- Testing
- 3 mg/kg of caffeine, 6 mg/kg of caffeine
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Healthy People
Effects of Social Isolation From Coronavirus; on Physical Activity, Quality of Life and Stress
The aim of our study is to investigate the physical activity, quality of life and stress levels of individuals living in their homes isolated due to coronavirus (COVID-19) disease.
- Trial name
- COVID-19 (NCT04319211)
- Testing
- Determination of physical activity, quality of life, stress levels of isolated people at home with the danger of coronavirus.
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul University - Cerrahpasa
Metabolism and Nutrition Disorder
Metabolic and Functional Impact of Various Breakfast Models
In the present study the investigators compared the hormonal and metabolic effects of three meal loads very popular among Italian eating habits, both in the resting- and exercising state.
- Trial name
- NCT03240757
- Testing
- Breakfast, exercise
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Ospedale San Donato
Covid19, Immunosuppression
Humoral and Cellular Immune Response to COVID-19 Vaccines in Immunocompromised and Healthy Individuals
Currently, the efficacy of COVID-19 vaccination in immunodeficient patients is unknown. Here the investigators aim to evaluate the efficacy of COVID-19 vaccines in immunodeficient patients compared to healthy controls.
- Trial name
- CoVVac (NCT04858607)
- Testing
- Blood sample, Saliva sample
- Where
- Austria
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Periodontitis
Interleukin 20 and Periodontal Tisuue Destruction
Periodontitis is an inflammatory disease that causes destruction of periodontal tissues. IL-20, on the other hand, is known as a potent angiogenic, chemotactic, and pro-inflammatory cytokine associated with various chronic…
- Trial name
- NCT06091800
- Testing
- biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Dental Plaque, Gingivitis
Effect of an Enzyme-containing Lozenge on Dental Biofilm in Healthy Individuals.
The purpose of the study is to assess the effect of an enzyme containing lozenge on dental plaque accumulation in healthy adults.
- Conditions
- Dental Plaque, Gingivitis, Microbial Colonization
- Trial name
- NCT05070507
- Testing
- Enzyme containing lozenge
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Obesity, Virtual Reality
The Effects of a Healthy Nutrition Program and Virtual Reality Applications on Body Composition
The most commonly used method in the management of body compositions of healthy individuals in the recent times is the application of physical activity together with a healthy nutrition (diet).
- Conditions
- Obesity, Virtual Reality, Body Composition, Healthy Nutrition
- Trial name
- NCT06110767
- Testing
- non-immersive virtual reality, Healty Diet Programme
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Erzurum Technical University
Healthy
Probiotics and Health-related Quality of Life in Individuals With Seasonal Allergies
In this randomized, double-blind, placebo-controlled study, participants with seasonal allergies will receive a daily probiotic or placebo for 8 weeks.
- Trial name
- JEN (NCT02349711)
- Testing
- Probiotic mixture
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Florida
MCG Reference Intervals Determination for Healthy Adults, Health, Subjective
Determination of MCG Reference Intervals in Healthy Individuals
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting cardiac abnormalities. However, the results of MCG cannot be evaluated without defined reference intervals.
- Trial name
- NCT06198777
- Testing
- Magnetometer
- Where
- China
- Volunteers
- 2,396 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University