Clinical trials: HEALTHY INDIVIDUALS
Healthy Individuals, Diabetes
Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Individuals
In vivo confocal microscopy (IVCM) has been used in clinical settings for more than 25 years, and is noninvasive, rapid and easily repeatable technique to investigate ocular surface disorders.
- Conditions
- Healthy Individuals, Diabetes, Hypertension, Fabry Disease
- Trial name
- NCT04025801
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hypercholesterolemia
LIP-01 in Hypercholesterolemia
The purpose of this study is to determine a safe and tolerable dose of LIP-01
- Trial name
- NCT00966225
- Testing
- LIP-01
- Where
- 2 sites in United States, Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Afexa Life Sciences Inc
Obesity, Insulin Resistance
"Can Soluble-CD163 Discriminate Between Healthy and Unhealthy Obese Individuals?"
CD163 is a membrane bound receptor primary expressed in monocytes and macrophages. A soluble variant of CD163 (sCD163) is present in plasma and is elevated in pathological condition activating the monocyte-macrophage system.
- Conditions
- Obesity, Insulin Resistance, Type 2-diabetes, Inflammation
- Trial name
- sCD163 (NCT01463449)
- Testing
- gastric bypass
- Where
- 2 sites in Denmark
- Volunteers
- 31 people
- Sponsor
- University of Aarhus
Physical Fitness
The Acute Effect Of Instrumental-Assisted Soft Tissue Mobilization Technique on Physical Fitness Parameters
The aim of this study is to evaluate the effect of Instrument Assisted Soft Tissue Mobilization (IASTM) on the acute effects of physical fitness parameters in healthy male individuals.
- Trial name
- NCT06252896
- Testing
- INSTRUMENTAL-ASSISTED SOFT TISSUE MOBILIZATION TECHNIQUE, NO INTERVENTION
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nuh Naci Yazgan University
Healthy
Dynamic Electrostimulation on the Abdominal Muscles in Healthy Individuals
To determine the immediate effects on the abdominal musculature, assessed by ultrasound (RUSI), due to the application of electrostimulation using whole body electrostimulation together with physical exercise in healthy people…
- Trial name
- NCT05117203
- Testing
- WB-EMS (Whole body electrostimulation), EMS, WB-EMS off
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Autonomic Dysfunction, Autonomic Imbalance
Non-Invasive Bioelectronic Analytics
Biomarkers can be evaluated to provide information about disease presence or intensity and treatment efficacy. By recording these biomarkers through noninvasive clinical techniques, it is possible to gain information about the…
- Conditions
- Autonomic Dysfunction, Autonomic Imbalance, Autonomic Nervous System Diseases, Vagus Nerve Autonomic Disorder
- Trial name
- NIBA (NCT04100486)
- Testing
- Standing-Squatting-Standing Test, Deep Breathing Test, Cold Pressor Test
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Muscle Spasticity, Hypertonia, Muscle
Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals
To assess the safety and tolerability of single and multiple doses of MTR-601 in normal healthy volunteers under fed and fasted conditions. To evaluate the plasma and urine pharmacokinetics (PK) of MTR-601.
- Conditions
- Muscle Spasticity, Hypertonia, Muscle, Cerebral Palsy, Multiple Sclerosis
- Trial name
- NCT06117020
- Testing
- MTR-601
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Motric Bio
Mild Cognitive Impairment
CBD for Individuals at Risk for Alzheimer's Disease
This is a double-blind, randomized controlled trial designed to test the effects of cannabidiol (CBD) on validated biomarkers of Alzheimer's disease (AD) progression, and behavioral, neurocognitive, and clinical measures, with…
- Trial name
- NCT05822362
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- University of Colorado, Denver
Influenza, COVID-19
A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Combined Modified RNA Vaccine Candidate Against COVID-19 and Influenza.
The purpose of this study is to understand the safety and effects of a combined influenza and COVID-19 vaccine. This combined vaccine is compared to separate vaccines for the protection against influenza and SARS-CoV-2.
- Trial name
- NCT06178991
- Testing
- Influenza and COVID-19 Combination A, Licensed influenza vaccine, COVID-19 Vaccine
- Where
- 106 sites in United States
- Volunteers
- 8,795 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Smallpox
High Dose IMVAMUNE® in Vaccinia-Naive Individuals
The purpose of this research is to compare the ability of a new investigational smallpox vaccine called IMVAMUNE® to produce a strong immune response against smallpox disease if given as one single, higher dose compared with two…
- Trial name
- NCT00879762
- Testing
- MVA Smallpox Vaccine
- Where
- 2 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Individuals With Perceived Stress
Effectiveness of Stress Free Now: an Internet-based Mindfulness Program for Stress Management
This research will examine whether an Internet-based mindfulness program for stress management produced positive outcomes for participants and is technologically feasible
- Trial name
- NCT01595555
- Testing
- Stress Free Now
- Where
- United States
- Volunteers
- 684 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Influenza
Trial to Assess the Shedding,Immunogenicity, and Safety of FluMist Administered to Healthy Individuals 5-49 Years of Age
To describe the proportion of individuals 5-49 years of age who shed vaccine strain viruses. To describe the duration of shedding of vaccine viruses in individuals 5-49 years of age.
- Trial name
- NCT00192140
- Testing
- FluMist
- Where
- 11 sites in United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Schizophrenia
The Effect of Psychoeducation on Healthy Lifestyle Behaviors in Individuals With Schizophrenia
Definition: Schizophrenia is a chronic mental disorder that causes drastic changes in life quality and life functions, characterized by behavioural, cognitive and affective state deterioration.
- Trial name
- NCT05259748
- Testing
- Psychoeducation Based on the Transtheoretical Model on Healthy Lifestyle Behaviors
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Hatay Training and Research Hospital
Interstitial Lung Diseases (ILD), Healthy Individuals
Exercise Capacity, Muscle Oxygenation, and Physical Activity Between Patients With Interstitial Lung Disease
Interstitial lung diseases (ILD) are a group of chronic respiratory diseases that cause significant mortality and morbidity worldwide.
- Conditions
- Interstitial Lung Diseases (ILD), Healthy Individuals, Exercise Capacity, Muscle Oxygenation
- Trial name
- NCT06948942
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cystic Fibrosis
Comparison of Physical Activity, Exercise Capacity, Quality of Life, Cognitive Function and Coronavirus Phobia Levels of Adult Cystic Fibrosis Patients With Healthy Individuals With Telerehabilitation
The purpose of this study was to evaluate physical activity, exercise capacity, quality of life, cognitive status level and coronavirus phobia level of adult cystic fibrosis patients and compare with the findings of healthy…
- Trial name
- NCT04673331
- Testing
- exercise capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Volunteers
Osteopathic Bowel Techniques and Their Effects on the Autonomic Nervous System in Healthy Individuals
INTRODUCTION: The autonomic nervous system (ANS) is responsible for controlling several visceral functions, including the motility and secretion of the gastrointestinal system (GIS).
- Trial name
- NCT05048823
- Testing
- Visceral Osteopathic Techniques, Simulated visceral techniques
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Instituto Docusse de Osteopatia e Terapia Manual
Obesity, Overweight
Predicting Adherence to a Heart-Healthy Diet in Lean and Obese Individuals
Background: Sticking to a diet plan can be difficult, but is important for many different health reasons. Some people seem to have a harder time following and sticking to a diet plan than others.
- Trial name
- NCT01862796
- Testing
- Underfeeding diet, Weight maintaining diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Muscle Development
Whole Milk Versus Whey Protein Supplement and Resistance Exercise
The purpose of the study is to examine the effects of consuming protein supplement (whey) compared to whole milk immediately after bouts of resistance training on muscular strength and body composition.
- Trial name
- NCT01580189
- Testing
- Whey protein, Chocolate milk, Sugar
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Heart Failure
Digital App and Platform for Supporting Medicines Control and Optimization in Older Individuals With Heart Failure
The intervention being piloted in this study is a novel system of supporting older individuals (>60 years old) with heart failure to self-manage their chronic condition through the use at home of a digital health tool that…
- Trial name
- NCT05353803
- Testing
- Digital App and Platform for Supporting Medicines Control and Optimizationin Older Individuals With Heart Failure
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- Clinika de Kay SL
Pulmonary Fibrosis, COPD
Multiple Breath Washout as a Method for Diagnosing Lung Diseases
Comparison of the new multiple-breath washout method (ndd Medizintechnik Zürich, Trueflow™/Truecheck™) with established methods of lung function diagnostics in patients with idiopathic pulmonary fibrosis, chronic obstructive…
- Conditions
- Pulmonary Fibrosis, COPD, Asthma
- Trial name
- NCT06179342
- Testing
- Multiple-Breath-Washout
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V