Clinical trials: HEALTHY VOLUNTEERS
Colorectal Cancer
The Clinical Application of 68Ga Labeled ssDNA Aptamer Sgc8 in Healthy Volunteers and Colorectal Patients
The protein tyrosine kinase-7 (PTK7) is overexpressed in various types of human cancers. As a specific imaging agent of PTK7, 68Ga-Sgc8 was investigated in this study to assess its safety, biodistribution and dosimetric…
- Trial name
- NCT03385148
- Testing
- 68Ga-Sgc8
- Where
- 2 sites in China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Healthy
Phase 1 Study(Additional) of URC102 in Healthy Subjects
The purpose of this study is to assess the safety, tolerability, PK and PD of URC102 in healthy subjects.
- Trial name
- NCT02524678
- Testing
- URC102
- Where
- South Korea
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- JW Pharmaceutical
Healthy Subjects
Phase I Study Multi Dose of 7.5mg Tolvaptan in Health Male
pharmacokinetics, pharmacological effects and safety of multi dose of 7.5mg Tolvaptan tablet in healthy male subjects
- Trial name
- NCT07166887
- Testing
- Tolvaptan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Otsuka Beijing Research Institute
Healthy
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Oral Doses of BI 11634 Solution in Healthy Male Volunteers
First evaluation of safety, tolerability, pharmacokinetics and the pharmacodynamic effect of BI 11634 on coagulation parameters
- Trial name
- NCT02214914
- Testing
- BI 11634 drinking solution, BI 11634 tablet
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Fasting Study of Zonisamide Capsules 100 mg and Zonegran® Capsules 100 mg
The objective of this study was to investigate the bioequivalence of Mylan's zonisamide, 100 mg capsules to Elan's Zonegran® 100 mg capsules following a single, oral 100 mg (1 x 100 mg) dose administered under fasting conditions.
- Trial name
- NCT00650052
- Testing
- Zonisamide Capsules 100 mg, Zonegran® Capsules 100 mg
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Healthy Volunteers
A First-in-Human Study of Single and Multiple Doses of anle138b in Healthy Subjects
The purpose of this study is to determine the safety, tolerability and blood levels of orally administered anle138b in healthy subjects.
- Trial name
- NCT04208152
- Testing
- anle138b
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- MODAG GmbH
Healthy
Safety and Pharmacokinetic Comparison of Sildenafil ODF and FCT Formulations in Healthy Korean Volunteers
This study investigates safety and pharmacokinetic comparison of Seoul Pharma's orally disintegrating film (ODF) formulation of sildenafil (test formulation) and Pfizer's "Viagra® (sildenafil)" Film Coated Tablet (FCT)…
- Trial name
- NCT01769638
- Testing
- SPO1101, SPO1101D
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Seoul Pharma Co., Ltd.
Pulmonary Arterial Hypertension
Effect of Food on BIA 5-1058
The aim of this study is to investigate the effect of food on the pharmacokinetic (PK) profile of BIA 5-1058 after a single dose in healthy subjects.
- Trial name
- NCT04991155
- Testing
- BIA 5-1058
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Healthy Volunteer
A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO5545965 in Healthy Volunteers
This single-center, randomized, investigator/subject-blind, adaptive multiple ascending-dose, placebo-controlled study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of RO5545965 in healthy…
- Trial name
- NCT01864226
- Testing
- RO5545965
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy Adult Volunteers
Clinical Trial to Compare Pharmacokinetics After Administration of ATB-101 or Co-administration of ATB-1011 and ATB-1012
To compare and evaluate safety and pharmacokinetic Characteristics after administration of ATB-101 or co-administration of ATB-1011 and ATB-1012 in fasted Healthy Adult Volunteers
- Trial name
- NCT05017987
- Testing
- ATB-101, ATB-1011, ATB-1012
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Autotelicbio
Healthy
Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers
The objective of the study is to obtain information about the safety and tolerability of BIIF 1149 BS45 (single dose: 40, 65, 100 mg), to determine the pharmacologically active dose (range) by performing a citric acid challenge…
- Trial name
- NCT02209714
- Testing
- BIIF 1149 BS
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Subjects
A Clinical Trial to Evaluate the Effect of Itraconazole and Rifampicin on ABSK021
This study is a single center, open lable and fixed sequence test conducted in healthy subjects to evaluate the pharmacokinetic effects of Itraconazole and Rifampicin on a single dose of ABSK021 Oral administration.
- Trial name
- NCT06089733
- Testing
- Part A ABSK201 and Itraconazole, Part A ABSK201 and Rifampicin
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Abbisko Therapeutics Co, Ltd
Healthy Participants Study
Effects of Voodoo Flossing on Ankle in Participants with Limited Ankle Dorsiflexion
In the case of normal walking patterns, the angle of plantarflexion (PF) at heel contact should be 0 to 5 degrees, the angle of dorsiflexion (DF) in the terminal stance should be 10 degrees, and the angle of PF should be 15-20…
- Trial name
- NCT06708052
- Testing
- voodoo flossing, Control group
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boung-hyoun Moon
Healthy Volunteer
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers
This is a double-blind, randomized, placebo-controlled, single ascending dose study to assess the safety, tolerability, and PK of ACHN-975 in normal healthy volunteers. This study will take place in the US at one clinical site.
- Trial name
- NCT01597947
- Testing
- ACHN-975
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Achaogen, Inc.
Depression
Study Evaluating the Effects of DVS SR and Paroxetine on the Pharmacokinetics of Desipramine in Healthy Subjects
The purpose of this study is to evaluate the effects of multiple doses of DVS SR and paroxetine on the pharmacokinetics of a single dose of desipramine in healthy subjects.
- Trial name
- NCT00329147
- Testing
- desvenlafaxine SR, desipramine, paroxetine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Healthy Subjects
Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases: Case-control
Connective tissue diseases (CTD) or systemic autoimmune diseases (SADs) as they are known today are a group of chronic inflammatory conditions with autoimmune aetiology with few treatment options and difficult diagnosis.Brest…
- Trial name
- PRECISESADST (NCT02890147)
- Where
- 17 sites in Austria, Belgium and 7 more
- Volunteers
- 649 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Thyroid Disease, Healthy
Pharmacogenomic Response to Thyrotropin-Releasing Hormone Stimulation in Healthy Volunteers: The Influence of a Common Type 2 Deiodinase Genetic Polymorphism on Serum T3
This study intends to examine how a common genetic pattern affects thyroid function. Recent studies have demonstrated that a substance (enzyme) produced by a gene has an important role in controlling circulating thyroid hormone…
- Trial name
- NCT00812149
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Healthy Volunteers, Cardiometabolic Diseases
A Study to See How Safe a New Medicine (NNC0705-0002) is in Healthy People
This study is testing NNC0705-0002, a new medicine that is being developed for conditions where inflammation may contribute to heart and metabolic health problems.
- Trial name
- NCT07797855
- Testing
- NNC0705-0002
- Where
- Netherlands
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy
CyclASol® Phase 1 Study
This study is intended to investigate the tolerability and the safety of Cyclosporine A containing CyclASol® eye drops compared to Placebo (vehicle) in a cohort of healthy volunteers.
- Trial name
- NCT02113293
- Testing
- CyclASol®
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Novaliq GmbH
Healthy
A Study of Single-dose ALXN2050 in Healthy Adults
This was a phase 1, first-in-human, single-center, randomized, double-blind (participants and investigator blind, sponsor open) placebo-controlled, single-ascending dose study of ACH-0145228 (ALXN2050) conducted in healthy adult…
- Trial name
- NCT05047458
- Testing
- ALXN2050
- Where
- New Zealand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Alexion Pharmaceuticals, Inc.
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