Clinical trials: HELICOBACTER PYLORI INFECTIONS
Helicobacter Pylori Infection
The Effects of a Synbiotic Addition on Eradication Therapy of Helicobacter Pylori Infection in Children
The aim of the study is to evaluate the effects of the synbiotic Bifidobacterium animalis ssp. lactis B94 plus inulin addition to the standard triple therapy on Helicobacter pylori infection eradication rates in children.
- Trial name
- NCT03165253
- Testing
- Bifidobacterium Animalis Oral Product, Amoxicillin Oral Tablet, Clarithromycin Oral Tablet
- Volunteers
- 69 people
- Sponsor
- Bulent Ecevit University
HELICOBACTER PYLORI INFECTIONS, Hyperprolactinaemia
Impact of Helicobacter Pylori Infection on Prolactin Levels in Reproductive-Age Women to Determine Whether H. Pylori Infection is Associated with Elevated Prolactin Levels and Assess the Clinical Implications
The research is a cross-sectional observational study conducted at Assiut University Hospital. It will involve 75 women aged 18-45 with confirmed H. pylori infection. The study will measure serum prolactin levels and H.
- Trial name
- NCT06870773
- Volunteers
- 75 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
The Safety and Tolerability, Pharmacokinetics of TNP-2092 Capsules in Combination With Rabeprazole Sodium Enteric-coated Tablets
A phase 1, single-center, double-blind, randomized, placebo-controlled clinical trial to evaluate the safety and tolerability, pharmacokinetics, and preliminary efficacy of multiple administrations of TNP-2092 Capsules in…
- Trial name
- NCT06337604
- Testing
- TNP-2092 capsules, Rabeprazole sodium enteric-coated tablets
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TenNor Therapeutics Inc.
Helicobacter Pylori
Helicobacter Pylori and Vonoprazan Dual Therapy
Our previous study included 119 Helicobacter pylori(H. pylori)-infected Chinese patients without previous eradication history who were randomized to low-or high-dose amoxicillin-vonoprazan regimens consisting of amoxicillin 1…
- Trial name
- NCT05649709
- Testing
- L-VA dual therapy, H-VA dual therapy
- Where
- China
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Nanchang University
Helicobacter Pylori Infection
Efficacies of Hybrid and High-dose Dual Therapies for the First-line Anti-H Pylori Treatment
Both hybrid and high-dose dual therapies developed by the scholars from Taiwan can achieve a high eradication rate for clarithromycin-resistant strains, and have a great potential to replace bismuth quadruple therapy in the…
- Trial name
- NCT05152004
- Testing
- Pariet, Amolin, Klaricid
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- Chang Gung Memorial Hospital
Helicobacter Pylori Infection
Comparing the Efficacy of Reverse Hybrid Therapy and Bismuth Quadruple Therapy
Reverse hybrid therapy achieves a higher eradication rate than bismuth quadruple therapy remained unanswered.
- Trial name
- NCT02547038
- Testing
- pantoprazole+bismuth+tetra+metro, (panto+amox+clar+metr)+(panto+amox)
- Where
- Taiwan
- Volunteers
- 352 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Helicobacter Pylori Infection
Efficacy and Safety of Dual Therapy for Helicobacter Pylori Eradication
The purpose of this study was to evaluate the Efficacy and Safety of Vonoprazan- amoxicillin dual therapy for Helicobacter Pylori eradication
- Trial name
- NCT05469685
- Testing
- Vonoprazan, Amoxicillin
- Where
- 10 sites in China
- Volunteers
- 914 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Helicobacter Pylori Infection
Clarithromycin, Amoxicillin, and Metronidazole Based Regimens to Treat Helicobacter Pylori Infections in Colombia
More than half of the world's population is infected with Helicobacter pylori, a bacterium that colonizes the human stomach. Although most infected subjects live free of symptoms and disease outcomes (except superficial…
- Trial name
- NCT00719420
- Testing
- Clarithromycin, Metronidazole, Amoxicillin (+Omeprazole), Clarithromycin, Amoxicillin, Omeprazole
- Where
- Colombia
- Volunteers
- 151 people
- Sponsor
- University of North Texas Health Science Center
H Pylori Infection
Genotypic Resistance Guided Therapy for Refractory H. Pylori Infection
The inviestigators aimed to compare the efficacy of genotypic resistance guided versus susceptibility testing guided therapy in the third line treatment for refractory H. pylori infection.
- Trial name
- NCT03555526
- Testing
- Esomeprazole 40mg, Amoxicillin, metronidazole
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Gastric Cancer, Cancer Prevention
Personalised Health Recommendations to the General Population Through an Integrated AI Guided
This clinical study aims to be used to implement and validate the AIDA tool in two phases: Phase 1: Risk stratification and personalised recommendations \& Model development Phase 2: Mechanistic Model (Bioresource) development \&…
- Conditions
- Gastric Cancer, Cancer Prevention, Helicobacter Pylori Infection, Artificial Intelligence
- Trial name
- AIDA (NCT06421324)
- Testing
- Health reccommendations
- Where
- Spain
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Helicobacter Pylori Infection
Control of Helicobacter Pylori Infection by Probiotics
Helicobacter pylori colonises an estimated 50% of the world´s population (Taylor \& Blaser, 1991; Go, 2002). Despite clear clinical guidelines on the treatment of this infection (Malfertheiner et al.
- Trial name
- NCT01115296
- Testing
- L. reuteri DSM 17938 and ATCC PTA 6475
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Helicobacter Pylori Infection
Comparison of Two Novel First-line Anti-Helicobacter Pylori Therapy
The Asian-Pacific Consensus Report has recommended that proton pump inhibitor (PPI)-clarithromycin-amoxicillin or metronidazole treatment for 7 to14 days is the first choice treatment for H pylori infection.
- Trial name
- NCT03383003
- Testing
- Nexium, Amolin, Klaricid
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- Chang Gung Memorial Hospital
H. Pylori Infection, Carcinogenesis
Study on the Probiotics Regulating miRNA in H. Pylori-induced Wnt/β-catenin Gastric Carcinogenesis.
Background. H. pylori has recognized as a type 1 carcinogen for gastric adenocarcinoma. Although H. pylori eradication promises to reduce the risk of gastric cancer, the regression rate of intestinal metaplasia (IM) after…
- Trial name
- NCT05544396
- Testing
- probiotic
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Cheng-Kung University Hospital
HELICOBACTER PYLORI INFECTIONS, Gastrointestinal Disease
Evaluation of IgY Antibody Efficacy in Egg Yolk Against Helicobacter Pylori in Bacterial Elimination and Clinical Symptoms Improvement of Gastrointestinal Patients
1. Investigating its effectiveness in removing bacteria in invivo conditions 2. Investigating the effectiveness in improving the clinical symptoms of patients
- Trial name
- Hp IgY (NCT06973889)
- Testing
- Helicobacter pylori eradication therapy
- Where
- 2 sites in Iran
- Volunteers
- 60 people
- Sponsor
- Mashhad University of Medical Sciences