Clinical trials: HEMORRHOIDS
Hemorrhoids, Anal Fissure and Fistula
Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia
Study Description: The goal of this clinical trial is to compare the duration of postoperative pain relief achieved with two different approaches to pudendal nerve block in patients undergoing elective perianal surgery.
- Conditions
- Hemorrhoids, Anal Fissure and Fistula, Perianal Abscess, Perianal Fistula
- Trial name
- NCT05990569
- Testing
- Ultrasound guided Pudendal nerve block
- Where
- Nepal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nepal Mediciti Hospital
Hemorrhoids
EnSeal Device Versus Ferguson Technique in Hemorrhoidectomy
This study will compare hemorrhoid surgery by comparing a sutureless heating device with the old standard hemorrhoid surgery. Patients will be followed closely for wound healing and satisfaction.
- Trial name
- NCT00853853
- Testing
- EnSeal Device, Ferguson Hemorrhoidectomy technique
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Steven Schechter, M.D.
Hemorrhoid Pain
Post Hemorrhoidectomy Anorectal Pain
This is a quality assurance trial to evaluate the effectiveness of guided breathing exercises on reducing the symptoms of hemorrhoidal disease in colorectal surgery patients.
- Trial name
- NCT03240185
- Testing
- deep breathing exercises
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Hemorrhoids
A Comparative Efficacy and Safety Study of Compound Carraghenates Cream With Mayinglong Musk Hemorrhoid Ointment in the Treatment of Hemorrhoids
The purpose of this study is to compare the therapeutic effect and safety of compound carraghenates cream with Mayinglong musk hemorrhoid (swollen veins in the lower part of the rectum or anus) ointment in the treatment of…
- Trial name
- NCT01881282
- Testing
- Carraghenates Cream, Mayinglong Musk Hemorrhoid Ointment
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Hemorrhoids, Postoperative Pain
Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy
The goal of this clinical trial is to evaluate whether oral nifedipine reduces postoperative pain and improves wound healing after hemorrhoidectomy in adult patients aged 18-65 years undergoing elective surgery for grade III or…
- Conditions
- Hemorrhoids, Postoperative Pain, Wound Healing, Analgesia
- Trial name
- NIFEDIPINE-HD (NCT07659665)
- Testing
- Nifedipine 20 Mg
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Hemorrhoid
Comparison of Outcome of Injection Sclerotherapy Versus Rubber Band Ligation for Second Degree Hemorrhoids
Objective of this study is to compare the outcome of Injection Sclerotherapy versus Rubber Band Ligation for second degree hemorrhoids in terms of bleeding and efficacy.
- Trial name
- NCT07199673
- Testing
- Injection Sclerotherapy, Rubber Band Ligation
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Gulab Devi Hospital
Hemorrhoids, Pregnancy
The Safety of Proctofoam-HC in the Third Trimester of Pregnancy
The purpose of this study is to evaluate the fetal safety of topical application of Proctofoam-HC®, an antihemorrhoidal, in the third trimester of pregnancy.
- Trial name
- NCT00405288
- Testing
- Proctofoam-HC®
- Where
- 2 sites in Canada
- Volunteers
- 408 people
- Sponsor
- The Hospital for Sick Children
Internal Hemorrhoid, Rectal Prolapse
Cap-assisted Endoscopic Sclerotherapy for Internal Hemorrhoids and Rectal Prolapse
This clinical trial aims to evaluate the efficacy and safety of long needle and short needle in the treatment of internal hemorrhoids and rectal prolapse through CAES (Cap-assisted endoscopic sclerotherapy).
- Trial name
- NCT03917056
- Testing
- Cap-assisted endoscopic sclerotherapy using long needle, Cap-assisted endoscopic sclerotherapy using short needle
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Hemorrhoids, Hemorrhoid Prolapse
Milligan-Morgan Versus Dearterialization With Mucopexy
Nowadays, there are several methods that can be used for grade III hemorrhoidal disease, according to Goligher classificiation. Milligan Morgan hemorrhoidectomy is considered the most effective treatment in many centers, even if…
- Trial name
- EMODART3 (NCT04863963)
- Testing
- Milligan Morgan
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Università degli Studi dell'Aquila
Hemorrhoids, Hemorrhoids Third Degree
PUSHES (Pudendal Block Versus Sacral ESP Hemorrhoidectomy Study)
The goal of this clinical trial is to learn if the sacral erector spinae plane block can provide equal or better pain control than the pudendal nerve block in adults undergoing hemorrhoid surgery.
- Trial name
- PUSHES (NCT07350460)
- Testing
- Pudendal block AL, Sacral ESP block AL
- Where
- Switzerland
- Volunteers
- 64 people
- Sponsor
- Andrea Saporito
Hemorrhoid, Hemorrhoidectomy
Cryotherapy for Post-Hemorrhoidectomy Pain
This prospective, patient-blinded randomized controlled trial will be conducted at Kasr Al-Ainy Hospital, Cairo University. Adult patients with grade III or IV hemorrhoids undergoing elective surgery will be randomized (1:1) to…
- Trial name
- NCT07714122
- Testing
- Milligan-Morgan Hemorrhoidectomy with Cryotherapy, Miligan-Morgan haemorroidectomy
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Cairo University
Hemorrhoids
Efficacy and Safety of RAdiofrequency Versus HAL- RAR DOppler in Hemorrhoidal Pathology
Haemorrhoids are composed of tissue rich in blood vessels and are present in all individuals inside the anus (internal haemorrhoids) or under the skin of the anus (external haemorrhoids).
- Trial name
- RADO (NCT04896268)
- Testing
- Radiofrequency, Arterial ligation then recto-anal repair with Doppler
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Elsan
Grade II Internal Hemorrhoids With Bleeding
A Phase III Clinical Trial Evaluating the Efficacy and Safety of TriThien Duoc Capsules in Grade II Internal Haemorrhoids Patients With Bleeding Compared to Diosmin.
A Phase III, randomized, double-blind, placebo-controlled clinical trial has been conducted to evaluate the efficacy and safety of Trĩ Thiên Dược capsules in people with grade II internal hemorrhoids with bleeding.
- Trial name
- NCT07369635
- Testing
- Intervention Group: Tri Thien Duoc Capsules, Control group (diosmin)
- Where
- Vietnam
- Volunteers
- 172 people
- Sponsor
- Hanoi Medical University
Haemorrhoids
Randomised, Double-blind, Placebo-controlled to Assess the Efficacy and Safety of the Food Supplement Microsmin® Plus
Haemorrhoids are variceal dilatations of the anal and perianal venous plexus and often develop secondary to the persistently elevated venous pressure within the haemorrhoidal plexus .
- Trial name
- NCT05750563
- Testing
- diosmin and micronized flavonoids
- Where
- Romania
- Volunteers
- 80 people
- Sponsor
- Giellepi S.p.A
Hemorrhoids External Thrombosed
Surgical Approach for Acute External Thrombosed Hemorrhoidal Disease
Acute external thrombosed hemorrhoidal disease (AETHH) is one of the emergent complications of hemorrhoidal disease that results in pain and loss of work force.
- Trial name
- NCT06009133
- Testing
- Conservative treatment, Surgical Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Konya Meram State Hospital
Hemorrhoidectomy, Pudendal Nerve
IntraopeRativE Use of periNeal Block for Hemorrhoidectomy
Perineal block with the anesthesia of the pudendal nerve's terminal branches allows to perform a hemorrhoidectomy with the optimal intraoperative and postoperative analgesia The purpose of this study is to assess the…
- Trial name
- IREN (NCT04288349)
- Testing
- perineal block with usage of one of solutions, epinephrine + ropivacaine +saline, epinephrine + saline
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Russian Society of Colorectal Surgeons
Hemorrhoids, Chronic Inflammatory Bowel Disease
Study "HEMORROIDAL SURGERY AND Chronic Inflammatory Bowel Disease"
Hemorrhoidal surgery is considered potentially harmful in patients with chronic inflammatory bowel disease (IBD). Patients with Crohn's disease may have ano-perineal involvement during the course of the disease or even before…
- Trial name
- CHRMICI (NCT04692194)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hemorrhoids
Treatment of Hemorrhoid With 1940nm Laser Procedure
Patients with hemorrhoids 2-3 st will be treated with laser 1940nm or sclerothearapy with Aethoxysklerol
- Trial name
- NCT05228054
- Testing
- laser procedure, sclerotherapy
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Hemorrhoids
Evaluation of Superior Rectal Arterial Embolization in Hemorrhoidal Disease
SRAE is a promising treatment of bleeding HD as a minimally invasive approach without sphincter damage nor direct mucosal anorectal trauma. Feasibility, efficacy and safety were studied in several trials.
- Trial name
- NCT05697562
- Testing
- Rubber band ligatures (RBL), Superior Rectal Artery Embolization (SRAE), Doppler-Guided Hemorrhoidal Artery Ligation (DG-HAL)
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Universitair Ziekenhuis Brussel
Hemorrhoids, Anal Fistula
Hemostatic and Analgesic Effect of Gel Foam and Gauze With Bosmin After Anal Surgery
To evaluate the hemostatic and analgesic effect of using gauze with Bosmin or Gelfoam after anal surgery.
- Trial name
- NCT05605080
- Testing
- Gelfoam, Bosmin gauze
- Where
- Taiwan
- Volunteers
- 292 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital