Clinical trials: HEMORRHOIDS
Hemorrhoids
Local Versus General Anaesthesia in Stapled Hemorrhoidectomy
The purpose of this study is to determine whether local or general anaesthesia in stapled hemorrhoidectomy leads to a shorter operation time with a better patient comfort.
- Trial name
- NCT00512044
- Testing
- Local anesthesia (pudendal block), general anesthesia (spinal and general)
- Where
- Switzerland
- Sponsor
- University of Lausanne Hospitals
Hemorrhoids
Irritation and Anal Bleeding in Patients Affected by Hemorrhoids.
Haemorrhoidal disease is an increasingly frequent benign condition, able to negatively affect the quality of working and relationship life in affected individuals.The primary objective of the study is the comparative assessment…
- Trial name
- IR-AN-BLEED (NCT03569930)
- Testing
- flavonoid-based supplements, Centella Complex, standard of care
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- University of Roma La Sapienza
Hemorrhoid
Endoscopic Rubber Band Ligation and Milligan-Morgan Hemorrhoidectomy for the Treatment of Grade II-III Internal Hemorrhoids: a Multicenter, Non-randomized Controlled Study
This study adopted a multicenter, non-randomized controlled clinical research design. Patients with internal hemorrhoids who met the inclusion criteria were assigned to the endoscopic rubber band ligation group (observation…
- Trial name
- NCT06794151
- Where
- China
- Volunteers
- 548 people
- Sponsor
- Weidong Tong
Third Degree Hemorrhoids
Doppler-guided Haemorrhoidal Artery Ligation With Suture Mucopexy vs. Suture Mucopexy Alone
Novel minimally invasive techniques were established for prolapsing haemorrhoids to minimise the drawbacks of the golden standard of haemorrhoidal treatment, conventional haemorrhoidectomy techniques.
- Trial name
- NCT02372981
- Testing
- mucopexy +/- Doppler-guided haemorrhoidal artery ligation
- Volunteers
- 40 people
- Sponsor
- Medical University Innsbruck
Hemorrhoids
Safety and Efficacy of Hydrocortisone and Lidocaine Treatment of Grade I and II Hemorrhoids
The objectives of this study are to assess the potential contribution of lidocaine hydrochloride or hydrocortisone acetate, alone or in combination, in topical cream preparations in the treatment of Grade I or II hemorrhoids and…
- Trial name
- Hydro/Lido (NCT02689856)
- Testing
- Hydrocortisone acetate and lidocaine hydrochloride, Hydrocortisone acetate, Lidocaine hydrochloride
- Volunteers
- 211 people
- Sponsor
- Citius Pharmaceuticals, Inc.
Hemorrhoids External Thrombosed
Surgical Approach for Acute External Thrombosed Hemorrhoidal Disease
Acute external thrombosed hemorrhoidal disease (AETHH) is one of the emergent complications of hemorrhoidal disease that results in pain and loss of work force.
- Trial name
- NCT06009133
- Testing
- Conservative treatment, Surgical Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Konya Meram State Hospital
Hemorrhoids
Prospective Randomized Trial About THD Versus Ligasure Hemorrhoidectomy for Grade III and IV Hemorrhoids
The study evaluates postoperative pain, morbidity, recurrence and quality of life, comparing two different strategies in the treatment of grade III and IV hemorrhoids: transanal hemorrhoidal dearterialization with mucopexy (THD)…
- Trial name
- THD-LIGA (NCT02654249)
- Testing
- Transanal hemorrhoidal dearterialization + mucopexy (THD)., Ligasure™ hemorrhoidectomy, THD anoscope and doppler
- Where
- 10 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Universitari de Bellvitge
Anal Fistula Surgery, Anal Fistula
The Use of Electronic Bidets Compared to Water Rinsing After Surgery for Anal Fistula or Haemorrhoidal Disease: a Pilot Study
There is still much to discover in the field of proctological postoperative care. There has already been some, albeit very little, research about its use post-haemorrhoidectomy as well as its possible effect on anal fissures, but…
- Conditions
- Anal Fistula Surgery, Anal Fistula, Hemorrhoidal Disease, Hemorrhoid Surgery
- Trial name
- bidet (NCT07874711)
- Testing
- Electronic bidet, standard water rinsing
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Hemorrhoids, Surgical Procedure, Unspecified
Multicentrique Prospective Evaluation of Radiofrequency Surgical Treatment of Homorrhoidal Disease
Hemorrhoids consist of a tissue rich in blood vessels and are present in all individuals inside the anus. Hemorrhoidal disease (HD) is when hemorrhoids become troublesome and cause symptoms such as pain, bleeding, prolapse or…
- Trial name
- RF-GREP (NCT04229784)
- Testing
- Radiofrewuency surgery
- Where
- France
- Volunteers
- 150 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Varicose Veins of Lower Limb, Hemorrhoids
HEMOVAR Study on Hemorrhoids and Varicose Veins
The HEMOVAR Study is a prospective observational study designed to evaluate the association between hemorrhoidal disease and lower extremity varicose veins.
- Trial name
- HEMOVAR (NCT07317492)
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Aydin Adnan Menderes University
Hemorrhoids, Internal
The Effect of Rubber Band Ligation in Bleeding Internal Hemorrhoids.
In this study, the researchers planned to compare the treatment results of patients undergoing rubber band ligation in addition to drug therapy in hemorrhagic internal hemorrhoids patients and those treated only with…
- Trial name
- NCT04290351
- Testing
- band ligation, oral 450 mg diosmin+50 mg hesperidin
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Hemorrhoids
Local Anaesthetic Day-care Haemorrhoidectomy Challenges Traditional Concepts - a Randomised Controlled Trial
Background: Local anaesthetic day-care open haemorrhoidectomy (LH) is feasible, cheap and may be the cost-effective surgical approach to third degree haemorrhoids.
- Trial name
- NCT00503269
- Testing
- Hemorrhoidectomy
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Anus Diseases, Gastrointestinal Diseases
Evaluation of the Effectiveness of a Topical Medical Device in Wound Healing and Symptom Relief in the Postoperative Period of Open Excisional Hemorrhoidectomy (The Emor Study)
This multicenter randomized controlled phase IV trial aims to compare the clinical efficacy of a gel containing a Propionibacterium extract and a gel with hyaluronic acid and silver sulfadiazine in the degree of epithelialization…
- Conditions
- Anus Diseases, Gastrointestinal Diseases, Intestinal Diseases, Cicatrization
- Trial name
- NCT06872151
- Testing
- Gel containing a Propionibacterium extract, Hyaluronic acid and silver sulfadiazine
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- University of Cagliari
Hemorrhoids Internal, Hemorrhoids Second Degree
Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal Hemorrhoids
This Phase II study will compare rectal artery embolization with operative hemorrhoidectomy in adults with symptomatic bleeding grade 2 and 3 internal hemorrhoids.
- Conditions
- Hemorrhoids Internal, Hemorrhoids Second Degree, Hemorrhoids Third Degree
- Trial name
- HemEmbo (NCT07844629)
- Testing
- Rectal Artery Embolization, Operative Hemorrhoidectomy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Colorado, Denver
Chronic Constipation, Constipation
Perineal Self-Acupressure
The primary aim of this study is to test a non-medicinal technique for chronic constipation. The core of the technique is to have subjects repeatedly press on and massage their perineum before defecation to fragment and soften…
- Conditions
- Chronic Constipation, Constipation, Hemorrhoids
- Trial name
- NCT01867944
- Testing
- Perineal Self-Acupressure, Educational Control
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Hemorrhoids
Data on the Impact of Different Treatment on the Quality of Life of Patients With Acute and Chronic Hemorrhoid Disease
The program is aimed at obtaining data on the impact of the method and type of treatment on the quality of life of patients with acute or chronic hemorrhoids with option of conservative treatment with Detralex
- Trial name
- EQUALISER (NCT03743311)
- Testing
- Hemorrhoidectomy, Thrombectomy , Operation on Longo method, Detralex, Combined therapy
- Where
- Russia
- Volunteers
- 1,032 people
- Sponsor
- Servier Russia
Hemorrhoid Pain
Post Hemorrhoidectomy Anorectal Pain
This is a quality assurance trial to evaluate the effectiveness of guided breathing exercises on reducing the symptoms of hemorrhoidal disease in colorectal surgery patients.
- Trial name
- NCT03240185
- Testing
- deep breathing exercises
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Postoperative Pain
Postoperative Pain and Tenesmus After Doppler-Guided Hemorrhoidal Artery Ligation With or Without Mucopexy
Hemorrhoidal disease is one of the most common anorectal disorders affecting adults worldwide. Doppler-guided hemorrhoidal artery ligation (HAL) is a minimally invasive surgical technique that has gained popularity because of its…
- Trial name
- NCT07710053
- Testing
- HAL + Mucopexy, HAL Alone
- Volunteers
- 150 people
- Sponsor
- Ali Genc
Lateral Internal Sphincterotomy, Hemorrhoidectomy
Hemorrhoidectomy With or Without Lateral Internal Sphincterotomy in Management of Patients With Hemorrhoids
This study aims to compare the lateral internal sphincterotomy versus no lateral internal sphincterotomy during hemorrhoidectomy in the management of patients with hemorrhoids.
- Conditions
- Lateral Internal Sphincterotomy, Hemorrhoidectomy, Hemorrhoids
- Trial name
- NCT06884774
- Testing
- Hemorrhoidectomy with lateral internal sphincterotomy, Hemorrhoidectomy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Minia University
Hemorrhoids
Trans-radial Superior Rectal Artery Embolisation for Haemorrhoids
Endovascular embolisation is already a common procedure for bleeding haemorrhoids in the acute setting, where surgical options are not possible or have been exhausted.
- Trial name
- NCT06175325
- Testing
- Trans-radial embolisation of haemorrhoids
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University Hospitals of North Midlands NHS Trust