Clinical trials: HEMORRHOIDS
Hemorrhoids, Fistula
Comparison Study of the Effect of Enema in Anal Surgery
To evaluate whether receiving enema before anal surgery or not affects the postoperative recovery and complications.
- Trial name
- NCT05602987
- Testing
- enema, no enema
- Where
- Taiwan
- Volunteers
- 282 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Hemorrhoidal Disease, Cervical Cancer Radiation Complications
A Clinical Study on Alleviating Hemorrhoids-related Symptoms of Pelvic Radiation Therapy
The goal of this clinical trial is to reduce the acute hemorrhoids-related symptoms for cervical cancer patients with hemorrhoids who need postoperative pelvic radiation therapy, including prolapse, local burning, bleeding…
- Trial name
- ACS-RT (NCT07175584)
- Testing
- anal canal-sparing techniques
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Pain Management, Hemorrhoids Third Degree
Topical Lidocaine 23%/Tetracaine 7% Ointment for Post-Hemorrhoidectomy Analgesia: A Randomized Controlled Trial
The goal of this clinical trial is to learn if a topical ointment containing two local anesthetics (lidocaine 23% and tetracaine 7%) can reduce pain after hemorrhoid surgery in adults.
- Conditions
- Pain Management, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids Second Degree
- Trial name
- NCT07688031
- Testing
- Lidocaine 23% / Tetracaine 7% topical ointment (compounded)
- Where
- Chile
- Volunteers
- 74 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Surgical Remove of Hemorrhoids
Safety and Efficacy of the Addition of Morphine Chloride to a Low Dose of Bupivacaine as Intradural Anaesthetic for the Removal Surgery of the Hemorrhoids
A single blind, randomized, with blinded evaluation by third parties clinical trial is carried out to assess the analgesic efficay of the addition of morphine chloride to a low dose solution of spinal local anaesthetic compared…
- Trial name
- NCT02046772
- Testing
- Bupivacaine low dose, Bupivacaine standard dose, Morphine Chloride
- Where
- 2 sites in Spain
- Volunteers
- 63 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias
Haemorrhoids
The Relationship Between Haemorrhoids and Pelvic Vein Reflux
This case series aims to find out in a group of female patients suffering from haemorrhoids, how many of them have pelvic vein reflux that feeds into their haemorrhoids.
- Trial name
- NCT02039570
- Testing
- Transvaginal scan
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- The Whiteley Clinic
Haemorrhoid
Traditional Ferguson Hemorrhoidectomy vs Stapled Hemorrhoidopexy
This study aimed to compare the short- and long-term outcomes of stapled hemorrhoidopexy (the procedure for prolapsed hemorrhoids, PPH) with anoplasty versus traditional Ferguson method for the treatment of patients with grade…
- Trial name
- NCT05959577
- Testing
- Stapled hemorrhoidopexy with anoplasty, Ferguson hemorrhoidectomy
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Second-degree Hemorrhoids
Efficacy and Safety of Polidocanol Foam 3% in the Treatment of II Degree Hemorrhoidal Disease
Hemorrhoidal disease (HD) is one of the oldest and most common proctologic diseases that has been described with an estimated prevalence between 4.4% and 86%.
- Trial name
- SCLEROFOAM (NCT03791775)
- Testing
- Polidocanol foam (Atossisclerol® 3%)
- Where
- Italy
- Volunteers
- 183 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Hemorrhoidal Disease
HAL-RAR Technique for Treating Hemorrhoids
A wide variety of methods has been proposed for treating hemorrhoidal disease with excisional hemorrhoidectomy remaining the gold standard.
- Trial name
- NCT04778124
- Testing
- Hemorrhoidal Arterial Ligation (HAL) and Recto Anal Repair (RAR), Excision of thrombosed hemorrhoid / Hemorrhoidectomy /
- Volunteers
- 105 people
- Sponsor
- Amalia Fleming General Hospital
Hemorrhoids Internal, Hemorrhoids Second Degree
Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal Hemorrhoids
This Phase II study will compare rectal artery embolization with operative hemorrhoidectomy in adults with symptomatic bleeding grade 2 and 3 internal hemorrhoids.
- Conditions
- Hemorrhoids Internal, Hemorrhoids Second Degree, Hemorrhoids Third Degree
- Trial name
- HemEmbo (NCT07844629)
- Testing
- Rectal Artery Embolization, Operative Hemorrhoidectomy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Colorado, Denver
Lateral Internal Sphincterotomy, Hemorrhoidectomy
Hemorrhoidectomy With or Without Lateral Internal Sphincterotomy in Management of Patients With Hemorrhoids
This study aims to compare the lateral internal sphincterotomy versus no lateral internal sphincterotomy during hemorrhoidectomy in the management of patients with hemorrhoids.
- Conditions
- Lateral Internal Sphincterotomy, Hemorrhoidectomy, Hemorrhoids
- Trial name
- NCT06884774
- Testing
- Hemorrhoidectomy with lateral internal sphincterotomy, Hemorrhoidectomy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Minia University
Perianal Fistula, Fissure in Ano
Perianal Nerval Block in Proctological Interventions
The aim of this study is to evaluate whether a local perianal block performed during a proctological intervention can reduce the postoperative pain.
- Conditions
- Perianal Fistula, Fissure in Ano, Hemorrhoids
- Trial name
- NCT03405922
- Testing
- 40 mL Ropivacain 0.5%
- Where
- Switzerland
- Volunteers
- 166 people
- Sponsor
- University Hospital, Basel, Switzerland
Hemorrhoids
Hemorrhoidectomy Only Versus Hemorrhoidectomy With Lateral Internal Sphincterotomy
The aim of this study was to access the comparison of pain and complications after hemorrhoidectomy with or without lateral sphincterotomy.
- Trial name
- NCT06588374
- Testing
- lateral internal sphincterotomy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemorrhoids
Effectiveness & Safety of Neofitoroid® in Hemorrhoidal Disease
Evaluation of the effect and safety of NeoFitoroid® in reducing symptoms in patients with hemorrhoidal disease.
- Trial name
- NCT03545724
- Testing
- Neofitoroid®
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Aboca Spa Societa' Agricola
Hemorrhoidectomy, Third Degree Hemorrhoids
Hemorrhoidectomy in Patients With Grade III and IV Disease:Harmonic Scalpel Compared With Conventional Technique
Hemorrhoidectomy is the treatment of choice for grade 3 and 4th degree hemorrhoids. Various surgical technique has been used to improve the outcome of the procedures performed in respect to operative time ,post operative pain and…
- Conditions
- Hemorrhoidectomy, Third Degree Hemorrhoids, Fourth Degree Hemorrhoids, Operative Time
- Trial name
- NCT03938714
- Testing
- Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Services Hospital, Lahore
Inflammatory Bowel Diseases, Anal Fissure
Laser Versus Surgery in Anal Diseases in Inflammatory Bowel Patients
This is a randomized comparative clinical trial carried out to compare between laser ablation and surgery in treating anal diseases in inflammatory bowel diseases patients and find out if one is superior to the other.
- Conditions
- Inflammatory Bowel Diseases, Anal Fissure, Hemorrhoids
- Trial name
- NCT06216223
- Testing
- treatment of anal diseases in inflammatory bowel patients, Laser, traditional surgery
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Zagazig University
Hemorrhoids
Safety and Efficacy of CITI-002 in Adult Patients With Moderate Grade Hemorrhoids
A Randomized Phase 2 double blind study which aims to determine the safety and efficacy of CITI-002 cream in adult patients with Goligher's grade II or III hemorrhoids.
- Trial name
- NCT05348200
- Testing
- Monad 1, Monad 2, Monad 3
- Where
- 16 sites in United States
- Volunteers
- 304 people
- Sponsor
- Citius Pharmaceuticals, Inc.
Hemorrhoids, Haemorrhoids
Effect of Early Warm Water Sitz Bath on Urinary Retention After Hemorrhoidectomy
Background: Hemorrhoid is one of the most common chronic anorectal diseases. The prevalence rate is about 44%. It occurs in adults aged 45-65 years.
- Conditions
- Hemorrhoids, Haemorrhoids, Piles, Hemorrhoidal Disease
- Trial name
- NCT04535765
- Testing
- early warm water sitz bath, Regular time warm water sitz bath
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- Cathay General Hospital
Hemorrhoidal Disease, Hemorrhoid Pain
Argon Plasma Coagulation in Open Excisional Hemorrhoidectomy
This prospective single-center randomized clinical trial evaluates whether the use of argon plasma coagulation (APC) during open excisional hemorrhoidectomy reduces postoperative pain and perioperative morbidity compared with…
- Conditions
- Hemorrhoidal Disease, Hemorrhoid Pain, Hemorrhoidectomy
- Trial name
- ARGO (NCT07587892)
- Testing
- open hemorrhoidectomy using argon plasma coagulation, open hemorrhoidectomy using momopolar coagulation
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Hemorrhoid Pain, Hemorrhoids
Topical Analgesia Post-Haemorrhoidectomy
Symptomatic haemorrhoids, or piles, have significant effects on quality of life. The treatment for advanced disease is surgical excision (haemorrhoidectomy) which is extremely effective.
- Trial name
- NCT04276298
- Testing
- Metronidazole cream, Metronidazole and Diltiazem cream, Metronidazole and Lidocaine cream
- Where
- New Zealand
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Hemorrhoids, Embolization, Therapeutic
Transarterial Coil Embolization of the Superior Rectal Arteries for Treatment of Stage II Hemorrhoids
This study will evaluate short , mid and long term efficacy of transarterial coil embolization of the superior rectal arteries (Emborrhoid techinque) for treatment the hemorrhoidal disease.
- Trial name
- NCT03805087
- Testing
- Transarterial coil embolization
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Humanitas Clinical and Research Center