Clinical trials: HIV/STI Incidence
HIV Infections
Botswana TDF/FTC Oral HIV Prophylaxis Trial
This study tested whether taking a pill of tenofovir and emtricitabine (two antiretroviral medicines) was safe for sexually-active young adults in Botswana without HIV infection and whether it reduced their risk of getting an HIV…
- Trial name
- TDF2 (NCT00448669)
- Testing
- Tenofovir Disoproxil Fumarate 300 mg + Emtricitabine 200 mg
- Where
- 2 sites in United States, Botswana
- Volunteers
- 1,219 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections
Open Label Extension (OLE) of the TDF2 Study, Botswana
This study is an open label and is an extension to the TDF2 study in which the investigators offered daily oral tenofovir/emtricitabine (TDF/FTC) for a maximum of 12 months to HIV uninfected former participants of the TDF2 study.
- Trial name
- TDF2-OLE (NCT04318210)
- Testing
- Tenofovir Disoproxil Fumarate 300 mg + Emtricitabine 200 mg
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV/STI Risk, HIV/STI Incidence
Addressing Psychosocial Needs and HIV Risk in Indian MSM
This study will develop and pilot test a combined individual and group-level behavioral HIV prevention intervention for men who have sex with men (MSM) in Chennai, India, addressing HIV risk within the context of broader…
- Trial name
- NCT01266122
- Testing
- Behavioral intervention
- Where
- 3 sites in United States, India
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Adherence, Medication, Risk Reduction
Prevention and Risk: Treatment With a New Emphasis on Relationships
This research examines the efficacy of an individually-delivered intervention tailored for YMSM in relationships. The intervention - termed PARTNER - utilizes a brief (4 session) motivational interviewing format to target…
- Conditions
- Adherence, Medication, Risk Reduction, Drug Use, Sex, Anal
- Trial name
- PARTNER (NCT03396367)
- Testing
- PARTNER, Education Intervention
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Sexually Transmitted Diseases
A Trial to Compare Antibacterial vs. Placebo Mouthwash to Reduce the Incidence of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men (MSM) Taking HIV Pre-Exposure Prophylaxis (PrEP)
The study involves a randomized placebo controlled trial that aims to assess if a mouthwash (Listerine cool mint, LCM) is able to reduce the cumulative incidence of gonorrhoea (Ng), chlamydia (Ct) and syphilis in men who have sex…
- Trial name
- PReGo (NCT03881007)
- Testing
- Mouthwash with LCM
- Where
- Belgium
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection
GonoScreen: Efficacy of Screening STIs in MSM
A Multicentre, controlled, randomized trial of 3 site (urethra, pharynx and rectum) sampling performed every 3 months (3x3) for Neisseria gonorrhoea (Ng)/Chlamydia trachomatis (Ct) screening (comparator) vs.
- Trial name
- GonoScreen (NCT04269434)
- Testing
- No Screening
- Where
- 5 sites in Belgium
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium