Clinical trials: HIV/STI Testing
Uterine Cervical Neoplasms, HIV/AIDS
Screening Test Accuracy of Gynocular™, HR-HPV Testing, VIA for Detection of Cervical Neoplastic Lesions, in Women Living With HIV
Cervical cancer in HIV-positive women is largely preventable through regular screening. The World Health Organization (WHO) recommends cervical screening for HIV-positive women every three years.
- Trial name
- NCT03931083
- Testing
- Screening for CIN2+/HSIL
- Where
- Zambia
- Volunteers
- 450 people
- Sponsor
- University of Bern
Hiv, Syphilis
MENJAGA: Continuous Quality Improvement for Antenatal HIV, Syphilis and Hepatitis B Testing in Indonesia
Elimination of mother-to-child-transmission (EMTCT) of HIV, syphilis and hepatitis B are key priorities in Indonesia, the fourth most populous country in the world.
- Conditions
- Hiv, Syphilis, Hepatitis B
- Trial name
- MENJAGA (NCT06058286)
- Testing
- Continuous quality improvement
- Where
- Indonesia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Yanri Wijayanti Subronto, MD, PhD,
HIV Infections
Safety and Efficacy of a Three-Dose Regimen of an Adenoviral HIV Vaccine (MRKAd5 HIV-1 Gag/Pol/Nef) in HIV Uninfected South African Adults
The purpose of this study is to determine the safety, efficacy, and tolerability of a three-dose regimen of an adenovirus-based HIV-1 vaccine in healthy South African adults.
- Trial name
- NCT00413725
- Testing
- MRKAd5 HIV-1 gag/pol/nef
- Where
- 5 sites in South Africa
- Volunteers
- 801 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Central Nervous System Diseases
Clinical Trial of Brain-Penetrating HIV Drugs to Prevent Cognitive Impairment in China
This primary aim of the project is to determine the association between antiretroviral therapy that better distributes into the central nervous system and prevention of HIV-associated neurocognitive impairment.
- Conditions
- HIV Infections, Central Nervous System Diseases, Dementia
- Trial name
- NCT01340950
- Testing
- zidovudine-lamivudine-nevirapine, tenofovir-lamivudine-efavirenz
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- University of California, San Diego
HIV, HIV Infections
Video-based Counseling & Rapid HIV Testing for Teens
This study evaluated the educational effectiveness of a youth-friendly pre-test video (derived from a previous qualitative study) and compared it with in-person HIV pre-test counseling.
- Trial name
- NCT00836550
- Testing
- Video, in-person HIV pre-test counseling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- North Bronx Healthcare Network
HIV (Human Immunodeficiency Virus), Hepatitis C
Testing of a Navigation Intervention for Hepatitis C and HIV
This study will evaluate the efficacy of navigation for hepatitis C treatment in people living with both HIV and HCV with criminal justice involvement.
- Trial name
- LINKHCV (NCT04499651)
- Testing
- Navigation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV Seropositivity, HIV Testing
Free HIV Testing in Private Biological Laboratories: A New Offer to Encourage HIV Testing
The program " Au labo sans ordo " aims to increase HIV testing coverage, in order to improve the first stage of the HIV care cascade in Paris and the Alpes-Maritimes, areas facing a much higher HIV epidemic than the other regions…
- Trial name
- ALSO (NCT04030689)
- Testing
- data collected from patient file
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
HIV Infections, Antiretroviral Therapy
Improving Clinic Attendance for Medication Collection Among HIV Positive Individuals in Nepal
Antiretroviral therapy (ART) has been a game changer in the context of HIV-epidemic. From 2005 to 2015, HIV-related deaths have fallen by 45% thanks to ART.
- Conditions
- HIV Infections, Antiretroviral Therapy, HIV Seropositivity
- Trial name
- NCT03367130
- Testing
- Mobile phone reminder
- Where
- Nepal
- Volunteers
- 468 people
- Sponsor
- Tokyo University
HIV Infection
Capravirine to Treat Children With HIV Infection
This study will test the safety, side effects and anti-HIV activity of different doses of capravirine in children and adolescents with HIV infection.
- Trial name
- NCT00006519
- Testing
- Capravirine
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- National Cancer Institute (NCI)
Human Papilloma Virus Related Cervical Carcinoma
The Women's Screening and Self-Testing Program (PROMETA) Study
This proposal directly addresses the ability to safely scale-up a Screen-Triage-Treat approach to cervical cancer screening. The investigators propose to capitalize on a pool of screen-eligible women accessing routine care within…
- Trial name
- PROMETA (NCT06810739)
- Testing
- HPV DNA testing be self-collected vaginal swab
- Where
- Mozambique
- Volunteers
- 8,445 people
- Sponsor
- Tulane University
Hiv
Testing Two Models of PrEP Delivery in OBGYN Clinics
The HIV Center for Clinical and Behavioral Studies, the Albert Einstein College of Medicine and the Alliance for Positive Change will test two healthcare models that integrate PrEP into OBGYN services.
- Trial name
- NCT05015855
- Testing
- NP-PC PrEP, OBGYN-PrEP
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
HIV Infections, HIV Seronegativity
A Blood Test to Look at Cells of the Immune System in Healthy Children
The purpose of this study is to learn more about some of the immune cells in the blood (CD4 cells, for example) of healthy children in order to better understand the differences in the blood cells of children infected with HIV.
- Trial name
- NCT00001109
- Where
- 45 sites in United States, Puerto Rico
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, STI
EASY-TESTS: Evaluation of the Acceptability of Pre-exposure Prophylaxis (PrEP) Among Men Who Have Sex With Men (MSM) Who Accepted Targeted HIV/STI Testing, Recruited Through a Community-based Outreach Approach, Both Digital and In-person.
Acceptability of a PrEP program among MSM and TG visiting a geolocated community application or a community physical place of sociability and having accepted a targeted screening for HIV, Hepatitis B, C and STIs.
- Trial name
- EASY-TESTS (NCT05949814)
- Testing
- acceptability of a PrEP program among HIV-negative MSM and TG
- Where
- France
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Centre de santé sexuelle Le 190
HIV Infections
Developing a Chatbot to Promote HIV Testing
In this study, the feasibility of a Chatbot in promoting HIV testing in men who have sex with men in Kuala Lumpur, Malaysia will be studied.
- Trial name
- NCT04910984
- Testing
- Chatbot messages, Attention-matched educational materials
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV Infections
Selective Exposure in HIV Prevention
Unfortunately, people most at risk for HIV are the least likely to enroll and remain in prevention programs. In our past work, we have learned how to increase enrollment in such programs among this group.
- Trial name
- NCT01152281
- Testing
- Maximal Control, Instrumental and Empowering, Minimal Control
- Where
- United States
- Volunteers
- 722 people
- Sponsor
- University of Illinois at Urbana-Champaign
HIV Infection
Impact of HIV Self-testing Among Female Sex Workers in Kampala, Uganda
HSPOT is a cluster-randomized trial designed to determine whether HIV self-tests are acceptable and improve HIV testing rates and HIV status knowledge among female sex workers in Kampala, Uganda.
- Trial name
- HSPOT (NCT02846402)
- Testing
- Oral HIV Self-Testing
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
HIV/AIDS
PrEP Communication Intervention for Female Clients of a Needle Exchange
This study will identify perceptions of PrEP in women who inject drugs (WWIDs) and develop and pilot test a targeted intervention that will be embedded in a large, urban syringe exchange program through an extensive formative…
- Trial name
- NCT03541642
- Testing
- Enhanced Intervention, Basic Intervention
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Temple University
HIV-1-infection
Kenya HIV Self-Testing in PrEP Delivery
In a three-arm, randomized trial, the investigators will test the use of HIV-1 self-testing to decrease the frequency and burden of clinic visits for PrEP while resulting in equivalent PrEP adherence and HIV testing.
- Trial name
- NCT03593629
- Testing
- 6-month PrEP + blood-based HIV self-test, 6-month PrEP + oral fluid HIV self-test
- Where
- Kenya
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Prevention, Sexually Transmitted Diseases
HOME Study: a Combination Support Package to Increase Uptake of PrEP and HIV/STI Testing
Home HIV self-testing has been FDA approved and allows users to read their own HIV test results at home, while home sexually transmitted infection (STI) test self-collection allows men to use a swab at home and mail it in for…
- Conditions
- HIV Prevention, Sexually Transmitted Diseases, Pre-Exposure Prophylaxis
- Trial name
- NCT03138135
- Testing
- HOME Study intervention, Control
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
AIDS
Comparison of Facility and Home-based ART Delivery Systems in Uganda
The study is a 3-year, randomized trial to compare ART delivery through two different models: a) ART delivered through health facilities by clinically qualified staff and b) home-based care in which lay workers, i.e.
- Trial name
- NCT00144365
- Testing
- Antiretroviral therapy
- Where
- Uganda
- Volunteers
- 1,453 people
- Sponsor
- Centers for Disease Control and Prevention