Clinical trials: HIV Antiretroviral Therapy (ART) Adherence
Acute HIV Infection, Acquired Immunodeficiency Syndrome
HAART Adherence Among HIV-infected Persons and the Factors Affecting Treatment Adherence
The general objective of this study is to evaluate HAART adherence in Estonia and the factors affecting adherence; and the impact of an individual adherence enhancement counselling and treatment monitoring model (Advanced…
- Conditions
- Acute HIV Infection, Acquired Immunodeficiency Syndrome, Medication Adherence
- Trial name
- NCT01369056
- Testing
- Advanced Adherence Counseling (AdvAdh)
- Where
- Estonia
- Volunteers
- 150 people
- Sponsor
- University of Tartu
HIV Antiretroviral Therapy (ART) Adherence, PMTCT
Optimizing Prevention and Care for Pregnant and Postpartum Adolescent Girls and Young Women With HIV in Tanzania
The goal of this clinical trial is to find better ways to care for pregnant and postpartum adolescent girls and young women (AGYW) aged 15-24 years with HIV in Tanzania, and to prevent them from passing HIV to their babies.
- Conditions
- HIV Antiretroviral Therapy (ART) Adherence, PMTCT, Pregnancy, Retention in Care
- Trial name
- ENGAGE (NCT06605053)
- Testing
- Co-produced intervention to optimize PMTCT care engagement
- Where
- 2 sites in Tanzania
- Volunteers
- 222 people
- Sponsor
- Karolinska Institutet
Risk Behavior, Medication Adherence
Secondary HIV Prevention and Adherence Among HIV-infected Drug Users
This study will test whether 3H+ (Holistic Health for HIV) is comparable to the original HHRP+ (Holistic Health Recovery Program) in reducing HIV risk behaviors and improving ART (Antiretroviral Therapy) adherence in a randomized…
- Conditions
- Risk Behavior, Medication Adherence, HIV
- Trial name
- NCT01741311
- Testing
- 3H+ (Holistic Health for HIV), HHRP+ (Holistic Health Recovery Program)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Connecticut
HIV Infections, Adherence, Medication
Technology Based Community Health Nursing to Improve Combination Anti-Retroviral Therapy (cART) Adherence and Virologic Suppression in Youth Living With HIV
Human immunodeficiency virus (HIV) infection has disproportionately persisted as a public health threat to adolescents and young adults (AYA) from minority communities in the United States.
- Trial name
- Tech2Check (NCT03600103)
- Testing
- Tech2Check
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Johns Hopkins University
Human Immunodeficiency Virus
Optimizing Retention in Care and Adherence to Anti-retroviral Therapy Amongst Adolescents Living With HIV in Rwanda
HIV has now become the leading cause of death amongst adolescents in Africa with over 2.1 million adolescents (aged 10-19 years old) living with HIV today.
- Trial name
- NCT04531605
- Testing
- YBank program
- Volunteers
- 72 people
- Sponsor
- Youth Development Labs, Inc dba YLabs
HIV Infections
A Comparison of Adherence Rates to Ritonavir and Its Accompanying Protease Inhibitor
Pharmacologic boosting of protease inhibitors with ritonavir has become standard practice in antiretroviral therapy. Patients are instructed to take ritonavir at the same time as its accompanying protease inhibitor.
- Trial name
- NCT00432783
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Montefiore Medical Center
HIV/AIDS
Effectiveness of Intensive Adherence Counselling Among People Living With HIV/AIDS With Low-level Viraemia in Uganda.
Uganda uses a threshold of 1,000 copies/ml to determine HIV viral non-suppression among people living with HIV/AIDS (PLHIV) on treatment, which is indicative of either poor adherence or HIV virologic treatment failure; as per the…
- Trial name
- NCT05514418
- Testing
- Intensive Adherence Counselling (IAC)
- Where
- 8 sites in Uganda
- Volunteers
- 136 people
- Sponsor
- Makerere University
HIV Infections
Evaluation of an Intervention on Adherence to Highly Active Antiretroviral Therapy (HAART) in HIV Infected Adults
It is known successful HIV therapy depends on the patients' ability to take their medicine regularly. This study is designed to find out if an intervention designed to help patients remember to take their medication is effective.
- Trial name
- NCT00203853
- Testing
- pillbox, wristwatch
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Chicago
HIV
WhatsApp Intervention to Assess the Effect of Messages in Adherence to Antiretrovirals in Young People With HIV in Peru
The goal of this clinical trial is to learn which type of messages is more efficacious to improve adherence to medication in young people living with HIV.
- Trial name
- NCT06500013
- Testing
- Self-designed messages, Standardized messages
- Where
- Peru
- Volunteers
- 131 people
- Sponsor
- Universidad Peruana Cayetano Heredia
HIV/AIDS
Adolescents Living With HIV (ALWH): Social Networks, Adherence and Retention
human immunodeficiency virus / acquired immunodeficiency syndrome (HIV/AIDS) is the second leading cause of death in Africa. Adolescents living with HIV (ALWH) are at increased risk for HIV-related morbidity and mortality due to…
- Trial name
- NCT04077047
- Testing
- iEngage
- Where
- 2 sites in United States, South Africa
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
HIV Infection, Adherence, Medication
Next Generation Ingestible Sensors for Medication Adherence Measurement
This study will investigate the use of a next-generation Reader as part of a digital pill system (DPS; ID-Cap System) to measure adherence to both antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) in people living…
- Conditions
- HIV Infection, Adherence, Medication, Adherence, Treatment, Pre-Exposure Prophylaxis
- Trial name
- NextGen (NCT05592613)
- Testing
- Next-generation Reader and ID-Cap System, Truvada for pre-exposure prophylaxis (PrEP), Biktarvy for antiretroviral therapy (ART)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Brigham and Women's Hospital
Human Immunodeficiency Virus
Impact of ART Adherence on HIV Persistence and Inflammation
The purpose of this study is to evaluate the relationship between anti-retroviral therapy (ART) adherence with levels of human immunodeficiency virus (HIV) reservoir and residual viremia in suppressed, HIV-infected individuals on…
- Trial name
- NCT02797093
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Colorado, Denver
HIV Infections
The Mochudi Prevention Project ART Protocol
The goal of the "Mochudi Prevention Project" is to reduce the number of new HIV infections in the village of Mochudi, Botswana by promoting a comprehensive package of interventions that have proven to be effective in preventing…
- Trial name
- NCT01583439
- Testing
- highly active antiretroviral therapy: Lopinavir/Ritonavir, Lamivudine, Zidovudine, Efavirenz, Tenofovir Disoproxil Fumarate, Emtricitabine
- Where
- Botswana
- Volunteers
- 11 people
- Sponsor
- Harvard School of Public Health (HSPH)
HIV
Adherence to Dolutegravir and Outcome
The main assumption is that the dolutegravir can get virologic suppression to suboptimal adherence levels (between 80 and 95%, and after treatment interruptions) where other molecules are not capable, due to their…
- Trial name
- DOLUTECAPS (NCT02878642)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
HIV
Antiretroviral Therapy Adherence and Secondary Prevention of Human Immunodeficiency Virus
In this study, investigators propose to randomize 165 human immunodeficiency virus positive patients to one of three 16-week treatment conditions: (1) standard care; (2) standard care + cell phone-based adherence reminders; or…
- Trial name
- NCT01760759
- Testing
- cell phone reminders, contingency management for adherence
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- UConn Health
HIV Infections
Adherence to Antiretroviral Therapy in HIV Infected Individuals in Assiut Governorate, Egypt
Egypt is a HIV low prevalence country but between 2010 and 2019 newly infected cases have more than quadrupled, and the rise continues at an alarming pace.
- Trial name
- NCT05953844
- Volunteers
- 278 people
- Sponsor
- Assiut University
HIV Infections
Pediatric Impact: Promoting Adherence to Medications Among HIV-infected Children
The purpose of the study is to develop and evaluate an intervention to promote adherence to HIV medications among children 5-12 years of age.
- Trial name
- NCT00134602
- Testing
- Needs assessment followed by tailored intervention
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- Centers for Disease Control and Prevention
HIV
Incentives to Promote Medication Adherence Among HIV-Infected Youth
Medication adherence is one of the most salient predictors of patient outcomes in the era following development of effective treatment for HIV infection.
- Trial name
- NCT02206906
- Testing
- Incentive intervention model
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- St. Jude Children's Research Hospital
HIV
An Educational and Supportive Counseling Program for Increasing Antiretroviral Use and Adherence in People With HIV
This study will develop and test the effectiveness of an educational and supportive counseling program called Preparing Patients to Start Antiretroviral Therapy in helping people with HIV make informed decisions about their…
- Trial name
- NCT00611429
- Testing
- Counseling sessions, Group workshop
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Human Immunodeficiency Virus
Mother and Infant Visit Adherence and Treatment Engagement Study
This is a 2x2 factorial cluster randomized trial of two interventions to improve retention and adherence for women and infants on Option B+.
- Trial name
- MOTIVATE! (NCT02491177)
- Testing
- cMM, Text Messaging
- Where
- Kenya
- Volunteers
- 1,338 people
- Sponsor
- University of Colorado, Denver