Clinical trials: HIV Infection, completed
HIV, Sexually Transmitted Infections
Connect 'n Unite: Couples-Based HIV/STI Prevention for Drug-Involved, Black MSM
The study has the following primary aims: (1) to test whether participants assigned to CNU (a 7-session, manualized intervention entitled "Connect 'n Unite") engage in lower HIV/STI behavioral risk compared to participants…
- Trial name
- CNU (NCT01394900)
- Testing
- CNU Intervention, WP Intervention
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV Infections, Tobacco Dependence
Efficacy and Safety of Varenicline Among HIV-infected Patients
Cigarette smoking is a major cause of illness among HIV-infected patients (non-AIDS defining malignancies (especially lung cancer), non-AIDS bacterial infections and cardio-vascular diseases).
- Trial name
- Inter-ACTIV (NCT00918307)
- Testing
- Varenicline
- Where
- France
- Volunteers
- 248 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV
PHASES: Provision of HIV Treatment at ATN Sites: An Evaluation for Stakeholders
This is an observational study involving retrospective and prospective medical record review covering a total maximum of 104 weeks (24 months) per subject.
- Trial name
- NCT02438592
- Where
- 14 sites in United States
- Volunteers
- 924 people
- Sponsor
- University of North Carolina, Chapel Hill
AIDS
Long-term Follow-up of Participants From Studies Evaluating GSK HIV Vaccine
The purpose of this long-term follow-up study is to assess the long-term health status of HIV-infected subjects who previously participated in GSK-sponsored trials evaluating the investigational HIV vaccine 732462.
- Trial name
- NCT01092611
- Testing
- Blood collection, GSK HIV vaccine 732462
- Where
- 41 sites in United States, France and 2 more
- Volunteers
- 190 people
- Sponsor
- GlaxoSmithKline
HIV Infections, COPD
Prevalence and Determinants of Chronic Obstructive Pulmonary Disease (COPD) in HIV+ Patients
The prevalence of COPD in HIV+ and AIDS patients is unknown. The pathophysiology of HIV infection and COPD might be of interest to both conditions.
- Trial name
- HIV&COPD (NCT00904384)
- Where
- Spain
- Volunteers
- 350 people
- Sponsor
- Cimera
HIV Infections
Effect of Tenofovir DF on Bone Metabolism in Children
This study will examine the long-term effects, particularly on bone metabolism, of the drug tenofovir DF in children with HIV infection.
- Trial name
- NCT00088309
- Testing
- Eye exam, Oral exam, CT scan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Hepatitis C, HIV
Study of A Combination Pill With GS-7977 and GS-5885 for Hepatitis C in People With HIV
Background: Present treatment for hepatitis C includes the use of a weekly injection and two different pills. This treatment is associated with serious side effects.
- Trial name
- NCT01878799
- Testing
- GS-7977/GS- 5885 FDC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Tuberculosis, HIV
Evaluation Of The Performance Of The Nitrate Reductase And Resazurin Titre Assay For The Detection of Mycobacterium Tuberculosis Complex From Sputum In A High Tb and Hiv Setting
The Principle objective of this study is To evaluate the performance of NRA, NRA-p and REMA-p for the detection of M. tuberculosis complex from sputum samples from adult pulmonary TB suspects in a high TB and HIV prevalence…
- Conditions
- Tuberculosis, HIV, AIDS, HIV Infections
- Trial name
- NRA RETA (NCT01053598)
- Where
- Uganda
- Volunteers
- 600 people
- Sponsor
- Epicentre
AIDS Related Lymphoma, AIDS-Associated Lymphoma
EPOCH Chemotherapy +/- IL-12 for Previously Untreated and EPOCH Plus Rituximab for Previously Treated Patients With AIDS-Associated Lymphoma
The prognosis of AIDS-related Non-Hodgkin's lymphoma is poor, especially in the relapsed setting. There is no standard treatment, and the few small studies that have been conducted have reported dismal outcomes.
- Trial name
- NCT00001563
- Testing
- Filgrastim, Rituximab, EPOCH
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- National Cancer Institute (NCI)
HIV Infection
Enhancement of Connect to Protect® (C2P)
The proposed study seeks to continue Connect to Protect® (C2P) community mobilization efforts that have developed coalitions that plan for and bring about structural changes for purposes of reducing HIV incidence and prevalence…
- Trial name
- NCT01492816
- Testing
- Community Mobilization
- Where
- 9 sites in United States
- Volunteers
- 927 people
- Sponsor
- University of North Carolina, Chapel Hill
Neuropathy
Analysis of Markers in the Blood Correlated With Neuropathic Pain
The purpose of this study is to analyze associations between symptoms and specific markers in the blood in patients suffering from neuropathic pain linked to diseases of different origin.
- Trial name
- NCT02208206
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Christoph Stein, MD
HIV Infections
Early Anti-Retroviral Treatment in HIV- Infected Children
EARTH study is conducted as part of the EPIICAL project. It is a prospective cohort study which aims to monitor clinical, virological and immunological features of HIV-positive, early treated children (≤90 days after diagnosis)…
- Trial name
- NCT05784584
- Testing
- Blood samples collection
- Where
- 6 sites in Mali, Mozambique and 1 more
- Volunteers
- 220 people
- Sponsor
- PENTA Foundation
Human Immunodeficiency Virus Infections
Attitudes and Beliefs and the Steps of HIV Care
Through a prospective observational cohort study enrolling patients newly diagnosed with Human immunodeficiency virus (HIV): Aim 1: Assess attitudes and beliefs about HIV disease and care over time and relate those attitudes and…
- Trial name
- NCT00749840
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Sarcoma
Antiviral Therapy in Treating Patients With Kaposi's Sarcoma With or Without HIV Infection
RATIONALE: Herpesvirus is found in Kaposi's sarcoma lesions in most patients; it is therefore possible that the herpesvirus has a role in causing Kaposi's sarcoma.
- Trial name
- NCT00019240
- Testing
- cidofovir
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
HIV Posterior Cheek Enlargement
HIV Posterior Cheek Enlargement
Altered contour of the lower face is a frequent complication of human immunodeficiency virus (HIV). HIV facial lipoatrophy or loss of facial fat commonly results from antiretroviral therapy.
- Trial name
- NCT01635504
- Testing
- Botulinum toxin A
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
HIV Infections
Impact of Different Integrase Inhibitor Based Regimen on Immune Activation Among HIV naïve Patient (INTATTI)
Low viral replication persistence and immune activation remain important therapeutic challenge in the new HAART era. They are associated with more rapid disease progression, increased risk of mortality and non-AIDS defining…
- Trial name
- INTATTI (NCT03280940)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
HIV Infections
Phase I/II Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive Patients
To determine the tolerance and side effects of a combination of lentinan and didanosine (ddI) compared with ddI alone. To determine whether the combination of lentinan and ddI produces a significant immunorestorative effect…
- Trial name
- NCT00002098
- Testing
- Lentinan, Didanosine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- AJI Pharma USA
Cardiovascular Disease, HIV
Statin Therapy to Improve Atherosclerosis in HIV Patients
In HIV patients, statin therapy will attenuate plaque inflammation, thus, making plaques less vulnerable, will deter plaque progression, and improve endothelial function.
- Conditions
- Cardiovascular Disease, HIV, Atherosclerosis, Inflammation
- Trial name
- NCT00965185
- Testing
- atorvastatin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
HIV/AIDS
Storytelling Narrative Communication Intervention for Smoking Cessation in Women Living With HIV
HIV has transformed into a chronic illness due to the advent of effective treatments in the absence of a cure. As a result, the prevalence of non-AIDS defining cancers (NADCs), including lung cancer, has increased three-fold…
- Trial name
- WISE (NCT03289676)
- Testing
- Storytelling Narrative Intervention
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Boston
HIV/AIDS
The BRIDGES Project: Bridging Resources to Engage Women in Integrated HIV Care and Support Services
The BRIDGES Project seeks to test a program intended to help women living with HIV who face specific barriers due to culture, gender, violence, trauma, adverse mental health, and substance use to be able to better access HIV…
- Trial name
- BRIDGES (NCT04295876)
- Testing
- The BRIDGES Project Intervention
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
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