Clinical trials: HIV Infection, completed
Cardiovascular Diseases, Heart Diseases
Effects of Highly Active Anti-Retroviral Therapy on Cardiovascular Health in Infants of HIV-Infected Mothers
This study will determine the impact of highly active antiretroviral therapy (HAART) on the developing cardiovascular system, the evolution of HAART-associated cardiovascular changes over time, and the association between…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, HIV Infections
- Trial name
- CHAART-1 (NCT00253682)
- Where
- 5 sites in United States
- Volunteers
- 167 people
- Sponsor
- University of Miami
HIV Prevention
Contraception and Menstrual Cycle Effect on Pharmacokinetics, Pharmacodynamics and Safety in Tenofovir Vaginal Gel Use
The purpose of the study is to examine the effects of two contraceptive methods and the menstrual cycle on the pharmacokinetics, pharmacodynamics of tenofovir 1% gel and the effect of the contraceptive methods on markers of…
- Trial name
- NCT01421368
- Testing
- Tenofovir 1% vaginal gel, Depo-medroxyprogesterone acetate (DMPA), Oral contraceptive: LNG 150 mcg and EE 30 mcg
- Where
- 3 sites in United States, Dominican Republic
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- CONRAD
HIV Infections, Tuberculosis
Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis
The purpose of this study is to determine if a relationship exists between the level of antituberculosis drugs (isoniazid, rifampin, ethambutol, and pyrazinamide) in the blood and the outcome of HIV-positive patients with…
- Trial name
- NCT00000950
- Testing
- Ethambutol hydrochloride, Isoniazid, Pyrazinamide
- Where
- 13 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
AIDS, Stress
Socioenvironmental Determinants of Psychological Functioning, Mental Health and AIDS in Mali
This project is a collaboration between the Centre Regional de Medecine Traditionnelle (CRMT) of the Malian National Institute of Public Health Research (INRSP) and the Section on Socioenvironmental Studies (SSES).
- Trial name
- NCT00339391
- Where
- Mali
- Volunteers
- 1,002 people
- Sponsor
- National Institute of Mental Health (NIMH)
HIV
Economic, Clinical and Quality of Life Assessment in Patients on Antiretroviral Therapy
The purpose of this study is to compare clinical, economical and quality of life (QOL) outcomes in patients living with HIV on zidovudine/stavudine regimen and tenofovir regimen. This study will be an unblinded randomized trial.
- Trial name
- NCT01694017
- Testing
- Tenofovir, Zidovudine
- Where
- India
- Volunteers
- 68 people
- Sponsor
- Tufts University
HIV-associated Lipodystrophy Syndrome
An Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK1265744 Administered as a Single Oral Dose and a Study to Describe the Pharmacokinetics of a Supratherapeutic Dose of GSK1265744 in Healthy Adult Subjects
This will be a two-part study in healthy adults. Part A is a phase 1, non-randomized, open label, single-dose, single-centre mass balance study utilizing a radiolabeled dose to investigate the recovery, excretion, and…
- Trial name
- NCT01848340
- Testing
- GSK1265744B (sodium salt) containing 14C-GSK1265744B, 150 mg GSK1265744B
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
HIV Infection
Evaluating Methods to Increase HIV Testing, Access to HIV Care, and HIV Prevention Strategies
This is a five-part study that will take place in the Bronx, New York (NY), and Washington, District of Columbia (DC). The different components of the study will focus on increasing the number of people being tested for HIV…
- Trial name
- NCT01152918
- Testing
- Linkage-to-Care Component: Financial Incentive (FI), Linkage-to-Care Component: Standard of Care (SOC), Viral Suppression Component: FI
- Where
- 2 sites in United States
- Volunteers
- 18,442 people
- Sponsor
- HIV Prevention Trials Network
Alcoholism, Child Abuse, Sexual
Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse
This study will evaluate the effectiveness of trauma-focused group therapy for reducing HIV-risk behavior and revictimization among adult women survivors of childhood sexual abuse (CSA).
- Conditions
- Alcoholism, Child Abuse, Sexual, Sexual Abuse, Sexual Behavior
- Trial name
- NCT00220597
- Testing
- Trauma-focused group therapy
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Stanford University
HIV/AIDS
A Phase I Trial to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted
This is a phase 1 first-in-human clinical trial to assess the safety, tolerability, and immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted, in up to 48 healthy adult HIV-negative volunteers.
- Trial name
- NCT03547245
- Testing
- eOD-GT8 60mer + AS01B/ DPBS sucrose/IM, DPBS Sucrose
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
HIV Infections, Histoplasmosis
A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDS
To evaluate the feasibility of itraconazole as (1) primary therapy in histoplasmosis and (2) maintenance therapy after completion of primary therapy. To evaluate the effect of therapy of CNS histoplasmosis.
- Trial name
- NCT00000975
- Testing
- Itraconazole
- Where
- 12 sites in United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Sexually Transmitted Infections
Evaluation of the Healthy Love Workshop, an HIV Prevention Intervention for African American Women
The purpose of this program evaluation is to determine whether the Health Love Workshop, a group-level HIV behavioral intervention, reduces HIV-related sex risk behaviors and increases HIV protective behaviors of African American…
- Trial name
- NCT00362375
- Testing
- Healthy Love Workshop, HIV/AIDS 101 Workshop
- Where
- United States
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Lung Carcinoma
Tailoring Shared Decision Making for Lung Cancer Screening in Persons Living With HIV
This study tailors a shared decision making intervention for lung cancer screening in persons living with human immunodeficiency virus (HIV).
- Trial name
- NCT04682301
- Testing
- Behavioral Intervention, Discussion (focus group), Discussion (feedback on SDM)
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Infection, Human Immunodeficiency Virus, HIV Infections
Phase 4 Study of Dolutegravir (DTG) in Russian Federation
DTG 50 milligram (mg) tablet was approved for marketing in Russian Federation; however, DTG is not currently available for subjects at Acquired Immune Deficiency Syndrome (AIDS) Centers as it is not available for order and supply…
- Trial name
- NCT03314064
- Testing
- Dolutegravir 50 mg
- Where
- 11 sites in Russia
- Volunteers
- 43 people
- Sponsor
- ViiV Healthcare
HIV Infection, Infant Risk for HIV Infection by MTCT
Prevention of Milk-Borne Transmission of HIV-1C in Botswana
The purpose of this study is to find the most effective and safe treatment to prevent the passage of HIV from an infected mother to her baby.
- Trial name
- Mashi (NCT00197587)
- Testing
- Nevirapine, No intervention
- Volunteers
- 1,200 people
- Sponsor
- Harvard School of Public Health (HSPH)
Sexual Behavior, Sexually Transmitted Diseases
Friendship Based HIV/STI (Sexually Transmitted Infections) Intervention for African American Females
The Project ÒRÉ intervention is a half-day community-based HIV/STI intervention program for friendship groups of adolescents that is tailored to African American culture.
- Conditions
- Sexual Behavior, Sexually Transmitted Diseases, HIV Infections
- Trial name
- NCT00109421
- Testing
- Project ÒRÉ
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections
Social Network Approach for Increasing Testing Coverage Among Men Who Have Sex With Men
HIV testing is essential in shortening the time to identify a new infection, the first 90 of the UNAIDS 90-90-90 targets. However, over one-third of the men who have sex with men (MSM) had never been tested for HIV; even if they…
- Trial name
- NCT04379206
- Testing
- HIV self-test kit, Graphical User Interface
- Where
- Hong Kong
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
HIV/AIDS
Storytelling Intervention to Promote Cervical Cancer Screening Uptakes Among Malawian Women Living With Human Immunodeficiency Virus
To develop a theory-based culturally-grounded storytelling-based intervention to increase cervical cancer screening among Malawian women living with HIV infection.
- Trial name
- NCT04307433
- Testing
- Storytelling narrative videos on tablets
- Where
- Malawi
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Boston
HIV, Insomnia
The Impact of Insomnia on Pain in HIV
The overall objective of this application is to investigate the impact of insomnia on pain, physical functioning, and inflammation in people living with HIV.
- Trial name
- HIPPI (NCT04298658)
- Testing
- Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5)sleep disorders-revised, Resmed ApneaLink Air device (Resmed, San Diego, CA)., Quantitative Sensory testing (QST)
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV Infections
Evaluating the Safety and Immunogenicity of Polyvalent DNA/gp120 HIV Vaccine in Healthy, HIV-uninfected Adults
The purpose of the study is to evaluate the safety, tolerability, and immunogenicity of polyvalent env (A,B,C,A/E)/gag (C) DNA and gp120 (A,B,C,A/E) protein vaccines (PDPHV201401) co-administered together with or without adjuvant…
- Trial name
- NCT04927585
- Testing
- env (A,B,C,A/E)/gag (C) DNA Vaccine, gp120 (A,B,C,A/E) Protein Vaccine, GLA-SE adjuvant
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Worcester HIV Vaccine
HIV, Hepatitis C
Chronic Hepatitis Intervention Project for Drug Users
The purpose of this study is to determine if a 6-session motivational interviewing intervention is more effective than a 6-session educational intervention at reducing behaviors that may lead to infection, transmission, and…
- Trial name
- NCT00596843
- Testing
- Motivational interviewing, Educational intervention
- Where
- United States
- Volunteers
- 851 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
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