Clinical trials: HIV Infection, completed
HIV Infections
Clinical Performance of Reveal G4 Rapid HIV-1 Antibody Test
To determine the efficacy of an improved rapid diagnostic test using venous whole blood and fingerstick whole blood. The clinical performance of Reveal G4 Rapid HIV-1 Antibody Test will be determined by comparing the results with…
- Trial name
- NCT02190578
- Testing
- Reveal G4
- Where
- 4 sites in United States
- Volunteers
- 1,649 people, healthy volunteers welcome
- Sponsor
- MedMira Laboratories Inc.
Tuberculosis, HIV Infections
Improving HIV/Tuberculosis Outcomes in Irkutsk
The investigators propose to examine the prospective influence of substance use patterns on HIV/tuberculosis adherence, pharmacokinetics and disease progression while developing novel methods for early detection and correction of…
- Conditions
- Tuberculosis, HIV Infections, Substance Use
- Trial name
- NCT03819374
- Where
- Russia
- Volunteers
- 53 people
- Sponsor
- University of Virginia
Hiv, AIDS
ALHIV Smartphone Game Study
This is a cluster-randomized controlled trial that aims to conduct comprehensive feasibility testing of a smartphone game in a sample of 120 adolescents living with HIV (ALHIV) ages 15-21 in Kisumu, Kenya, to determine whether…
- Conditions
- Hiv, AIDS, Adolescent Behavior, Treatment Compliance
- Trial name
- NCT06913660
- Testing
- MyGoals, Standard of care
- Where
- Kenya
- Volunteers
- 120 people
- Sponsor
- Emory University
Infection, Human Immunodeficiency Virus
Phase IIa Dose-ranging Study of GSK1349572 in HIV-1 Infected Adults
GSK1349572 is an integrase inhibitor that will be evaluated for the treatment of HIV infection. This phase IIa, multicenter, randomized, parallel, double-blind, dose ranging, placebo-controlled 'proof of concept' study is to be…
- Trial name
- NCT00708110
- Testing
- GSK1349572
- Where
- 18 sites in United States
- Volunteers
- 35 people
- Sponsor
- ViiV Healthcare
HIV
The Safety, Pharmacokinetic Profile and Efficacy of Raltegravir in HIV-infected Patients at Least 60 Years of Age
This is a phase IV, open label, prospective, one phase pharmacokinetic and observational study. Twenty HIV-1 infected subjects will be recruited, subjects will switch antiretroviral therapy to: tenofovir/emtricitabine 245/200 mg…
- Trial name
- NCT01335620
- Testing
- Raltegravir, Tenofovir, Emtricitabine
- Where
- 2 sites in United Kingdom
- Volunteers
- 19 people
- Sponsor
- Imperial College London
HIV Prevention, HIV Preexposure Prophylaxis
Streamlining the Efficiency of PrEP Implementation
This is a pilot facility-based direct-to-pharmacy PrEP refill delivery to streamline care pathway in Kenyan public health HIV facilities implementing PrEP.
- Conditions
- HIV Prevention, HIV Preexposure Prophylaxis, Implementation
- Trial name
- Efficiency (NCT04424524)
- Testing
- Direct-to-pharmacy oral PrEP refill visits
- Where
- Kenya
- Volunteers
- 746 people
- Sponsor
- University of Washington
Transgender Women, HIV/AIDS
Effects of Gender-Affirming Hormone Therapy Among Transgender Women
In this study, investigators plan to evaluate the cardiometabolic effects of initiating gender-affirming hormone therapy among transgender women with and without HIV.
- Conditions
- Transgender Women, HIV/AIDS, Cardiovascular Diseases, Metabolic Disease
- Trial name
- NCT04128488
- Testing
- Abdominal MR Imaging, Cardiac MRI/MRS, Oral Glucose Tolerance Testing
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
HIV
A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients.
For patients who are starting to take antiretroviral medication (to treat HIV) for the first time, there are now a variety of different medicines which may be taken together as a combination in order to form an effective…
- Trial name
- NCT01736761
- Testing
- Darunavir, Ritonavir and Rilpivirine
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- St Stephens Aids Trust
HIV, Depression
Pharmacokinetic Drug-drug Interaction Study Between RaltEgravir and CITALopram in Healthy Subjects (RECITAL).
Depression is the most common mental health disorder among HIV-patients. Recognizing and treating depression is important in order to improve quality of life and health outcomes in those living with HIV.
- Trial name
- RECITAL (NCT01978782)
- Testing
- raltegravir, citalopram
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
HIV Infection Primary
Kinetics of HIV-RNA Decay in Seminal Plasma of Men Treated by Dolutegravir at the Time of Primary HIV Infection
Sponsor: IMEA - Fondation Internationale Léon Mba C.H.U. Bichat - Claude Bernard 46, Rue Henri Huchard - 75018 PARIS Tél. : 01.40. 25. 63.
- Trial name
- DOLUPRIM (NCT02976259)
- Testing
- Dolutegravir
- Volunteers
- 20 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Methamphetamine Use Disorders, HIV
Transcranial Magnetic Stimulation for Methamphetamine Use Disorder in PLWH
The purpose of this study is to learn more about how accelerated theta burst stimulation affects methamphetamine craving and brain activity.
- Trial name
- NCT06830980
- Testing
- intermittent theta burst stimulation (iTBS), continuous theta burst stimulation (cTBS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Gopalkumar Rakesh
Sarcoma, Kaposi, HIV Infections
A Study of Doxorubicin in the Treatment of AIDS-Related Kaposi's Sarcoma
To study the natural course of AIDS related Kaposi's sarcoma and to determine the usefulness and safety of weekly administration of small doses of doxorubicin.
- Trial name
- NCT00000996
- Testing
- Doxorubicin hydrochloride
- Where
- 12 sites in United States
- Volunteers
- 48 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV/AIDS, Cognitive Impairment
A Randomized Pilot Trial Evaluating the Impact of a Yoga Intervention on Cognition in Older Adults Infected With HIV
Approximately 50% of people living with HIV (and as many as 80% over the age of 50) have difficulties with cognitive functions such as memory and thinking that can have a profound negative impact on activities of daily living and…
- Conditions
- HIV/AIDS, Cognitive Impairment, Aging, Mobility Limitation
- Trial name
- NCT03071562
- Testing
- Yoga-mindfulness
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Adria Quigley
HIV Infection, Infection, Human Immunodeficiency Virus
Healthy Volunteer Study To Assess The Bioavailability of GSK1265744 When Administered Orally Either When Fasted or Following a Meal.
To evaluate the single dose relative bioavailability of GSK1265744 10mg administered in either oral solution fasted, two 5mg tablets fasted, or two 5mg tablets following a moderate meal.
- Trial name
- NCT00812318
- Testing
- GSK1265744 10 mg oral solution, GSK1265744 5 mg tablet
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
HIV Infections, Cytomegalovirus Infections
Valganciclovir to Reduce T Cell Activation in HIV Infection
The purpose of this study is to determine whether treatment with valganciclovir decreases T cell activation levels among HIV-infected patients with asymptomatic cytomegalovirus (CMV) co-infection, potentially improving immune…
- Trial name
- NCT00264290
- Testing
- Valganciclovir
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
HIV Infections
Tenofovir-lamivudine-dolutegravir Combination as Second-line ART: a Randomised Controlled Trial
The strategy to support virological suppression on second-line antiretroviral treatment (ART) includes the provision of ART that has a low pill burden, good tolerability, low toxicity, is easily monitored, has a high barrier to…
- Trial name
- ARTIST (NCT03991013)
- Testing
- Dolutegravir 50 mg
- Where
- South Africa
- Volunteers
- 192 people
- Sponsor
- University of Cape Town
HIV-1, HIV Infections
Safety and Immunogenicity Study of Candidate HIV-1 Vaccine Given to Healthy Infants Born to HIV-1/2-uninfected Mothers
Objectives: Safety and immunogenicity of MVA.HIVA vaccine in 20-week-old healthy Gambian infants born to HIV-1/2-uninfected mothers.
- Trial name
- PedVacc001 (NCT00982579)
- Testing
- MVA.HIVA
- Where
- The Gambia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
HIV Infections
A Behavioral Intervention to Reduce Sexual Risk Among African-American Men Who Have Sex With Men
The purpose of this project is to test the efficacy of an HIV prevention behavioral intervention to reduce sexual risk among African-American men who have sex with men (MSM).
- Trial name
- NCT00691496
- Testing
- Behavioral intervention to reduce sexual risk among African-American men who have sex with men
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections
Online HIV Prevention Vignette Evaluation
This is an evaluation of the effect that an online live action, dramatic vignette about four gay men, two HIV positive and two HIV negative, struggling with the responsibility for safer sex has on the sexual behavior and HIV…
- Trial name
- NCT00249327
- Testing
- education
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Public Health Solutions
HIV Infections
Study on the Effect of Kaletra + Nevirapine as Maintenance Bitherapy Compared to a Triple Therapy Including Kaletra + Analogues in HIV Patients
The study aims to evaluate the changes in mitochondrial DNA (mDNA) by means of the mDNA/nuclearDNA (nDNA) ratio as a marker of mitochondrial toxicity following the interruption of nucleoside analogues.
- Trial name
- NCT00335686
- Testing
- Lopinavir-rtv (Kaletra): 3 capsules (600 mg)/12 h, Nevirapine (Viramune): 1 comp (200mg)/12h
- Where
- 24 sites in Spain
- Volunteers
- 67 people
- Sponsor
- Germans Trias i Pujol Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.