Clinical trials: HIV Test and Treat
HIV Infection
Evaluating Methods to Increase HIV Testing, Access to HIV Care, and HIV Prevention Strategies
This is a five-part study that will take place in the Bronx, New York (NY), and Washington, District of Columbia (DC). The different components of the study will focus on increasing the number of people being tested for HIV…
- Trial name
- NCT01152918
- Testing
- Linkage-to-Care Component: Financial Incentive (FI), Linkage-to-Care Component: Standard of Care (SOC), Viral Suppression Component: FI
- Where
- 2 sites in United States
- Volunteers
- 18,442 people
- Sponsor
- HIV Prevention Trials Network
HIV Infections
Immune Therapies and Anti-HIV Therapy Withdrawal in Controlling Viral Load
The purpose of this study is to determine if HIV-specific canarypox vaccine and/or interleukin-2 (IL-2) will control viral load (amount of HIV in the blood) after HIV treatment is withdrawn for a certain time period.
- Trial name
- NCT00013663
- Testing
- ALVAC(2)120(B,MN)GNP (vCP1452), Aldesleukin
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Simplified Model of Linkage and Retention to Care, Using a Mobile Unit and a Same-day Test and Treat Approach Among Excluded Population. (SIMPLIFIED)
Implementation of a model for access and retention of HIV care for vulnerable and excluded population using a mobile screening unit and a strategy of diagnosis and initiation of treatment with Bictegravir (BIC) 50 mg/…
- Trial name
- SIMPLIFIED (NCT05405751)
- Testing
- Bictegravir/Emtricitabine/Tenofovir Alafenamide 50 MG-200 MG-25 MG Oral Tablet [BIKTARVY]
- Where
- Spain
- Volunteers
- 101 people
- Sponsor
- Fundacion SEIMC-GESIDA
Human Immunodeficiency Virus
CARE Corrections: Technology for Jail HIV/HCV Testing, Linkage, and Care (TLC)
The purpose of this study is to determine whether an intervention (CARE+ Corrections) delivered to HIV-infected detainees within the DC Department of Corrections (DOC) and recently -released ex-detainees in the community can…
- Trial name
- CARE+ (NCT01721226)
- Testing
- Intervention Arm (computer-based CARE+ Corrections tool), Educational video on opiate overdose prevention
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- George Washington University
HIV Infections, Syphilis
Ending the HIV Epidemic Through Point-of-Care Technologies (EHPOC)
This study proposes to investigate the performance of existing and new technologies for HIV diagnosis, one of the key strategies for Ending the HIV Epidemic in the U.S.
- Trial name
- EHPOC (NCT04793750)
- Testing
- Cepheid GeneXpert HIV-1 Qual POC HIV VL test, DPP HIV-Syphilis test system, OraQuick
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
HIV/AIDS, TB - Tuberculosis
Xpert Ultra and Xpert HIV-VL in People Living With HIV
TB is increasingly diagnosed using the GeneXpert platform, which can be used for a variety of tests (not just TB). HIV viral load monitoring is required at least annually in patients on ART to detect failure of virologic…
- Conditions
- HIV/AIDS, TB - Tuberculosis, Antiretroviral Therapy, Highly Active
- Trial name
- NCT03187964
- Testing
- PLHIV Point of Care Xpert Ultra, PLHIV Point of Care Xpert VL
- Where
- South Africa
- Volunteers
- 1,053 people
- Sponsor
- University of Stellenbosch
Human Papilloma Virus Related Cervical Carcinoma
The Women's Screening and Self-Testing Program (PROMETA) Study
This proposal directly addresses the ability to safely scale-up a Screen-Triage-Treat approach to cervical cancer screening. The investigators propose to capitalize on a pool of screen-eligible women accessing routine care within…
- Trial name
- PROMETA (NCT06810739)
- Testing
- HPV DNA testing be self-collected vaginal swab
- Where
- Mozambique
- Volunteers
- 8,445 people
- Sponsor
- Tulane University
HIV Infections
HIV - Monotherapy in Switzerland (MOST-ch)
The investigators plan to conduct a two arm study, to compare failure rates in the central nervous system (CNS) and genital compartment in virologically fully suppressed patients continuing a highly active antiretroviral therapy…
- Trial name
- MOST (NCT00531986)
- Testing
- Lopinavir-Monotherapy, HAART
- Where
- 6 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Cantonal Hospital of St. Gallen
HIV Infections
Safety and Effectiveness of HIV-1 DNA Plasmid Vaccine and HIV-1 Recombinant Adenoviral Vector Vaccine in HIV-Uninfected, Circumcised Men and Male-to-Female (MTF) Transgender Persons Who Have Sex With Men
The purpose of this study is to determine the safety and efficacy of a VRC DNA/rAd5 vaccine regimen in healthy, circumcised men and male-to-female (MTF) transgender persons who have sex with men.
- Trial name
- NCT00865566
- Testing
- DNA plasmid vaccine, Recombinant adenoviral serotype 5 (rAD5) vector vaccine
- Where
- 22 sites in United States
- Volunteers
- 2,504 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infection
Study of Tests to Evaluate Effectiveness of Anti-HIV Drugs
The purpose of this study is to determine how laboratory tests called genotyping and phenotyping assess the effectiveness of antiretroviral drugs used to treat HIV infection.
- Trial name
- NCT00006494
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Prevention, Sexually Transmitted Diseases
STI Care Model to Reduce Genital Inflammation and HIV Risk in South African Women
The goal of this prospective cohort study is to determine if a model of care including point-of-care testing, immediate therapy, expedited partner therapy and test of cure will result in a higher cure rate and a lower recurrence…
- Trial name
- NCT03407586
- Testing
- Point-of-care STI testing
- Where
- South Africa
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
HIV, HIV - Human Immunodeficiency Virus
Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women
Purpose of this Study: The main purpose of this study is to adapt an existing evidence-based intervention, Project Accept Post-Test Support Services (PTSS) Module 3, specifically for pregnant and postpartum women living with HIV…
- Conditions
- HIV, HIV - Human Immunodeficiency Virus, Postpartum, Pregnancy
- Trial name
- WAT (NCT07064928)
- Testing
- Adapted Project Accept's Post-Test Support Services (PTSS) Module 3
- Where
- Ghana
- Volunteers
- 163 people
- Sponsor
- University of California, San Francisco
HIV Counseling and Testing, HIV Risk Behavior
Safe Spaces 4 Sexual Health
In an earlier study, the study team carried out an HIV/Sexually transmitted infection (STI) testing approach which found men who have sex with men (MSM) at-risk of getting or spreading HIV in online spaces and linked them to…
- Conditions
- HIV Counseling and Testing, HIV Risk Behavior, HIV Prevention
- Trial name
- SS4SH (NCT07133555)
- Testing
- Healthcare counseling service
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Stigma, Social, HIV/AIDS
Transgender Education for Affirmative and Competent HIV and Healthcare
Educational workshops are an efficacious strategy to increase healthcare providers' ability to provide gender-affirming care for transgender (trans) people.
- Conditions
- Stigma, Social, HIV/AIDS, Health Care Acceptability
- Trial name
- TEACHH (NCT04096053)
- Testing
- TEACHH
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Toronto
HIV
A Randomized Controlled Trial of HIV Testing and Linkage to Care at Community Corrections
The investigators propose to conduct both a randomized trial of HIV testing in community corrections, and a randomized trial of linkage to HIV care for people with HIV recruited through community corrections (probation and…
- Trial name
- NCT01366495
- Testing
- Project Bridge
- Where
- United States
- Volunteers
- 797 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
HIV
Urban Health Study II
The study will test an intervention to help HIV-positive people achieve consistency of HIV care while transitioning in and out of jail.
- Trial name
- NCT01402466
- Testing
- Standard Referral, Project Bridge
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- RTI International
Human Immunodeficiency Virus
Bringing South African Men Into HIV Counseling and Testing and Care
This clinical trial seeks to determine if male-centered recruitment increases men's testing for HIV and whether or not individualized introduction to clinics increases male engagement in treatment for HIV.
- Trial name
- NCT03794245
- Testing
- Men-Centered HIV Testing, Linkage to Care for HIV+ Men, Clinic-based HIV Testing
- Where
- South Africa
- Volunteers
- 1,806 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Opioid-use Disorder, IV Drug Usage
AWAITS: A Web-based E-health Application for Active Illicit Opioid Users
The purpose of this research study is to: 1. assess how participants like the AWAITS e-health application as measured by their feedback on the intervention 2.
- Conditions
- Opioid-use Disorder, IV Drug Usage, Overdose, Drug Addiction
- Trial name
- AWAITS (NCT03402672)
- Testing
- self-administered, e-health application
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Cincinnati
HIV/AIDS and Infections
Antiretroviral Regime for Viral Eradication in Newborns
This is a multi-center, randomized, controlled, open clinical trial. The trial will be carried out in five provinces in China. Pregnant women with HIV infection and at high risk of mother-to-child transmission of HIV will be…
- Trial name
- NCT02712801
- Testing
- Zidovudine, Nevirapine, Lamivudine
- Where
- 5 sites in China
- Volunteers
- 600 people
- Sponsor
- National Center for Women and Children's Health, China CDC
Hiv, Syphilis
MENJAGA: Continuous Quality Improvement for Antenatal HIV, Syphilis and Hepatitis B Testing in Indonesia
Elimination of mother-to-child-transmission (EMTCT) of HIV, syphilis and hepatitis B are key priorities in Indonesia, the fourth most populous country in the world.
- Conditions
- Hiv, Syphilis, Hepatitis B
- Trial name
- MENJAGA (NCT06058286)
- Testing
- Continuous quality improvement
- Where
- Indonesia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Yanri Wijayanti Subronto, MD, PhD,