Clinical trials: HIV Test and Treat
PTSD, Hiv
CPT-L to Improve Outcomes for Individuals With HIV and PTSD
This study plans to adapt and examine the acceptability and feasibility of an evidence-based PTSD treatment that has reduced other HIV transmission behavior (e.g., sexual risk), Cognitive Processing Therapy (CPT), at an HIV…
- Trial name
- NCT05275842
- Testing
- Cognitive Processing Therapy- Lifesteps (CPT-L), Lifesteps
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Medical University of South Carolina
HIV/AIDS, Sexually Transmitted Infection
The People Like Us Evaluation Study
The study is a pragmatic, randomized controlled trial design to evaluate an online video series developed by a community-based organization in Singapore for gay, bisexual and queer men.
- Conditions
- HIV/AIDS, Sexually Transmitted Infection, Homosexuality, Health Behavior
- Trial name
- NCT04021953
- Testing
- People Like Us Online Video Series Intervention, Sexual Health Pamphlet (Standard of Care)
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
HIV, Tuberculosis
Medical and Economical Impact of IGRAs Diagnosis of Latent Tuberculosis in HIV-infected Patients
Tuberculosis is a current infection during HIV infection. After infectious contact, some patients will develop tuberculosis some will only be infected without symptoms, they have Latent Tuberculosis Infection (LTBI) which can…
- Conditions
- HIV, Tuberculosis, Latent Tuberculosis Infection
- Trial name
- IGRAVIH (NCT00805272)
- Testing
- QTF-TB Gold and T-SPOT TB
- Where
- France
- Volunteers
- 536 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Drug Resistance
Impact of HIV Drug Resistance Testing, and Subsequent Change to an Individualized Therapy in Tanzania
The current therapy regimens in Sub-Saharan countries, consisting of standardized first and second line drug combinations, yield a high rate of treatment failure, even within the first 12 months of therapy (23).
- Trial name
- NCT03557021
- Testing
- HIV Drug resistance testing
- Where
- 3 sites in Tanzania
- Volunteers
- 1,250 people
- Sponsor
- Medical Mission Institute, Germany
Chlamydia, Gonorrhea
A Seek, Test, and Treat Intervention to Reduce Chlamydia Trachomatis Disparities
This study includes testing for four STIs (chlamydia, gonorrhea, syphilis, and HIV) at no cost. If positive, individual subjects will also be counseled and offered options for treatment for themselves and their sex partners that…
- Conditions
- Chlamydia, Gonorrhea, Hiv, Syphilis
- Trial name
- NCT06428643
- Testing
- Chlamydia, gonorrhea, syphilis, and HIV screening
- Where
- United States
- Volunteers
- 2,322 people, healthy volunteers welcome
- Sponsor
- Tulane University
HIV, Medication Adherence
Tel-Me-Box: Testing a New, Real-time Strategies for Monitoring HIV Medication Adherence in India
Currently available methods to monitor antiretroviral (ARV) adherence to HIV treatment and prevention, such as self-report, pill counts, medication electronic monitoring system (MEMS), and devices which wirelessly monitor…
- Trial name
- NCT03086655
- Testing
- Tel-me-box with reminder features, Tel-me-box
- Where
- India
- Volunteers
- 131 people
- Sponsor
- University of California, San Francisco
Substance Use
Pre-exposure Prophylaxis (PrEP) Uptake and Adherence Intervention for Women with Trauma-related Conditions
The investigators have previously developed an integrated bio-behavioral intervention to promote PrEP uptake and adherence in cisgender women who are undergoing treatment for trauma-related mental health conditions and who are at…
- Trial name
- NCT06558825
- Testing
- Integrated Intervention to Promote PrEP Uptake, Standard Treatment Condition
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The University of Texas Health Science Center, Houston
HIV
Same-Day HIV Testing and Treatment Initiation to Improve Retention in Care
The purpose of this study is to determine if same-day HIV testing and antiretroviral therapy (ART) initiation improves retention in care (as measured by the proportion of participants who are alive and in-care with an…
- Trial name
- NCT01900080
- Testing
- Same-Day HIV testing and ART initiation, Standard ART Initiation, Sub-Study: Same-Day ART, CD4 Count >500
- Where
- Haiti
- Volunteers
- 814 people
- Sponsor
- Brigham and Women's Hospital
HIV Infections, Antiretroviral Therapy
Improving Clinic Attendance for Medication Collection Among HIV Positive Individuals in Nepal
Antiretroviral therapy (ART) has been a game changer in the context of HIV-epidemic. From 2005 to 2015, HIV-related deaths have fallen by 45% thanks to ART.
- Conditions
- HIV Infections, Antiretroviral Therapy, HIV Seropositivity
- Trial name
- NCT03367130
- Testing
- Mobile phone reminder
- Where
- Nepal
- Volunteers
- 468 people
- Sponsor
- Tokyo University
HIV, Sexual Risk
WHC+ (Women's Health CoOp PLUS)
This study compares the effects of standard HIV test, treat and retain (TTR) practices with TTR plus a woman-focused enhanced strategy--Women's Health CoOp (WHC+) intervention) targeting hard-to-reach and vulnerable alcohol and…
- Conditions
- HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse
- Trial name
- NCT01497405
- Testing
- Test, Treat, Retain(TTR) + Women's Health CoOp (WHC), Test, Treat, Retain(TTR) only
- Where
- 2 sites in United States, South Africa
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- RTI International
HIV
Community-based Interventions to Increase HIV Testing and HIV Care Utilization
The purpose of this study is to conduct a cross-site evaluation of the Kaiser Permanente's Community-based Interventions to Increase HIV Testing and HIV Care Utilization Program, designed to support community-based interventions…
- Trial name
- NCT01867177
- Testing
- HIV testing, standard of HIV care, HIV care utilization
- Where
- United States
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cognitive Disorders, HIV Infections
HIV Levels in Cerebrospinal Fluid and Brain Function in Patients Receiving Anti-HIV Drugs
The purpose of this study is to see whether anti-HIV drugs that reduce HIV in the blood also reduce HIV in the cerebrospinal fluid (CSF). CSF is the fluid found around the brain and spinal cord.
- Trial name
- NCT00001103
- Where
- 26 sites in United States, Puerto Rico
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV
Impact on Linkage to HIV Care With Point of Care CD4 Testing and Home-based HIV Testing in Kenya
Randomised Controlled Trial to Assess Accuracy, Feasibility, Acceptability, Cost Effectiveness and Impact of Point of Care CD4 Testing on HIV Diagnosis, Linkage to Care and Time to Antiretroviral Therapy Initiation among HIV…
- Trial name
- CD4-POC (NCT02515149)
- Testing
- Point of care CD4 device (Alere PIMA)
- Where
- Kenya
- Volunteers
- 770 people
- Sponsor
- Centers for Disease Control and Prevention
Tuberculosis
Test and Treat TB: A Proof of Concept Trial in South Africa
The purpose of this study is (1) to establish the feasibility, yield, and clinical impact of a "Test \& Treat TB" strategy on a mobile HIV screening unit in South Africa and (2) to assess the cost and cost-effectiveness of this…
- Trial name
- Siyasiza (NCT02298309)
- Testing
- Test-and-Treat TB
- Where
- South Africa
- Volunteers
- 4,815 people
- Sponsor
- Massachusetts General Hospital
Hiv
Innovative Strategies to Increase ART Initiation and Viral Suppression Among HIV-positive Men in Malawi
Men in Sub-Saharan Africa are less likely to test for HIV, initiate ART, and more likely to initiate ART at later stages of disease.
- Trial name
- NCT04878601
- Testing
- Home-Based ART, Facility-Based ART
- Where
- Malawi
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Risk Behavior, HIV/AIDS
Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs
This study will evaluate the efficacy and cost-effectiveness of CHRP-BB - an integrated bio-behavioral approach that incorporates the use of PrEP - with an evidence-based behavioral approach aimed at enhancing PrEP adherence and…
- Conditions
- Risk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
- Trial name
- CHRP-BB (NCT03282890)
- Testing
- CHRP-BB
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Connecticut
HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV)
Combating Related Epidemics in HCV
This is a two-arm cluster randomized control trial to evaluate the effectiveness of a single-visit point-of-care (POC) test and treat bundle (intervention arm) compared to the current standard-of-care (SOC, control arm).
- Conditions
- HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV), HEPATITIS C (HCV)
- Trial name
- CREST (NCT07560046)
- Testing
- Cepheid GeneXpert HCV Test, Abbott Determine HIV - 1/2 Ag/Ab, Abbott Determine HbsAg 2
- Volunteers
- 1,280 people
- Sponsor
- Duke University
HIV
Integrated Care Delivery of HIV Prevention and Treatment in AGYW in Zambia
The study team will test a multilevel package of interventions to connect adolescent girls and young women (AGYW) with a source of regular care to provide a sustainable platform for successful implementation of regular human…
- Trial name
- NCT03995953
- Testing
- SHIELD intervention (Support for HIV Integrated Education, Linkages to care, and Destigmatization), Integrated wellness care (IWC) clinics
- Where
- Zambia
- Volunteers
- 2,150 people
- Sponsor
- RTI International
HIV Care Loss to Followup, HIV Antiretroviral Therapy (ART) Adherence
Developing and Testing a Digital Health Tool for INterseCtional Stigma Assessment and Reduction at Multiple Levels and mUltiple DimEnsions (INCLUDE) to Improve HIV Care in ART Centers in Nepal
People living with HIV (PLWH) have poor clinical outcomes when they are excluded from care due to intersectional stigma related to HIV, mental health (MH), and other dimensions.
- Conditions
- HIV Care Loss to Followup, HIV Antiretroviral Therapy (ART) Adherence, HIV Stigma, Mental Health Conditions
- Trial name
- INCLUDE (NCT07370298)
- Testing
- INCLUDE
- Where
- Nepal
- Volunteers
- 88 people
- Sponsor
- Possible
HIV Infections
Use of a Test That Evaluates How the Body Handles Insulin and Glucose
The purpose of this study is to find out if testosterone gel affects how the body handles insulin and glucose. Specific anti-HIV treatments may increase a patient's risk of certain diseases by causing metabolic problems such as…
- Trial name
- NCT00027092
- Where
- 8 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)