Clinical trials: HIV-infection/AIDS
Hepatitis C Virus, HIV
Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 or 4 HCV and HIV-1 Co-infection
This study will evaluate the antiviral efficacy, safety, and tolerability of ledipasvir/sofosbuvir (LDV/SOF) fixed-dose combination (FDC) administered for 12 weeks in hepatitis C virus (HCV) treatment-naive and…
- Trial name
- NCT02073656
- Testing
- LDV/SOF, RBV
- Where
- 41 sites in United States, Canada and 2 more
- Volunteers
- 335 people
- Sponsor
- Gilead Sciences
Human Immunodeficiency Virus Infection
A Drug-drug Interaction Study of SHR2150 on Healthy Chinese Volunteers
The study is a single-centre, open-label, fixed-sequence, self-controlled clinical trial. It is planned to enroll 20 healthy adult subjects. Subjects will take SHR2150 on Day 1 and Day 21, and take efavirenz from Day 7 to Day 26.
- Trial name
- NCT05141422
- Testing
- SHR2150 tablet、efavirenz
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
HIV Infections, Insulin Resistance
Diet, Exercise and/or Rosiglitazone for HIV-Associated Insulin Resistance
The purpose of this study is to determine if, in men and women with excess abdominal fat and insulin resistance, people with HIV infection respond differently than people without HIV to interventions that typically improve body…
- Conditions
- HIV Infections, Insulin Resistance, Obesity
- Trial name
- NCT00264251
- Testing
- Weight loss through diet and exercise, Rosiglitazone insulin sensitizing agent
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Hiv
Facilitating Routine HIV Testing Among MSM by a Subscription-based Self-test Distribution Model
The goal of this stepped wedge trial is to assess if a subscription-based HIV self-test distribution model could facilitate routine HIV testing in the men who have sex with men community.
- Trial name
- NCT06189729
- Testing
- Text reminder, HIV self-test
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
HIV Infections
Collection of Blood Samples From HIV Infected People
The purpose of this study is to collect blood samples from HIV infected individuals for use in future genetic studies.
- Trial name
- NCT00096772
- Where
- 83 sites in United States
- Volunteers
- 2,502 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Infection, Human Immunodeficiency Virus
Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults
The purpose of this study is to find at least one dose of BMS-955176 that will be safe, effective and tolerable for HIV-1 infected treatment naive adults.
- Trial name
- NCT02415595
- Testing
- BMS-955176, EFV, TDF/FTC
- Where
- 64 sites in United States, Argentina and 10 more
- Volunteers
- 210 people
- Sponsor
- ViiV Healthcare
Infection, Human Immunodeficiency Virus
A Study to Evaluate the Effects of Calcium Carbonate and Ferrous Fumarate on Pharmacokinetics of Dolutegravir in Healthy Adult Subjects
Human immune virus (HIV) infected subjects may take mineral supplements in combination with their antiretroviral medications. Calcium and Iron supplementations are commonly used and both of these have the potential to interact…
- Trial name
- NCT01762995
- Testing
- Dolutegravir 50 mg, Calcium Carbonate 1200 mg, Ferrous Fumarate 324 mg
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Alcohol Dependence
Reducing Alcohol Dependence Among HIV-Positive Individuals
The purpose of this study is to compare the effects of interventions for drinking-reduction and antiretroviral therapy (ART) adherence among HIV-positive primary care patients.
- Trial name
- NCT02501057
- Testing
- Clinician's Guide, Enhanced Motivational Interviewing, Enhanced Clinician's Guide
- Volunteers
- 133 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
HIV Infection, AIDS
Accuracy of the Pima™ CD4 Test for Enumeration of CD4+ T-Cell Counts
This is a multi-center study designed to assess the accuracy of Pima™ CD4 Test to enumerate CD4+ T-cells in whole blood over the measurement range expected for the intended population.
- Conditions
- HIV Infection, AIDS, HIV Infections
- Trial name
- NCT00951795
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abbott RDx Cardiometabolic
Acquired Immunodeficiency Syndrome, HIV Infections
A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of HIV/AIDS Complicated With Infection
The goal of this observational study is to determine the incidence and spectrum of opportunistic infections among Chinese HIV/AIDS patients at this stage, to find intervention targets, to construct an early warning prediction…
- Trial name
- NCT06280001
- Volunteers
- 500 people
- Sponsor
- Zhejiang University
HIV (Human Immunodeficiency Virus), Geriatric
Promoting Aging and Thriving With HIV
The pilot is an intervention of a geriatric assessment and management tool (PATH) in outpatient HIV clinics.
- Conditions
- HIV (Human Immunodeficiency Virus), Geriatric, Geriatric Assessment, HIV
- Trial name
- PATH (NCT07192419)
- Testing
- Promoting Aging and Thriving with HIV (PATH)-Implementation of a Tailored Geriatric Assessment and Management Strategy for HIV Care Settings
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Sarcoma, Kaposi, HIV Infections
A Study of DOX-SL in the Treatment of AIDS-Related Kaposi's Sarcoma
To evaluate the safety and effectiveness of Stealth liposomal doxorubicin hydrochloride (DOX-SL) in the long-term treatment of AIDS-related Kaposi's sarcoma (KS) in patients who previously had good responses to DOX-SL in…
- Trial name
- NCT00002319
- Testing
- Doxorubicin hydrochloride (liposomal)
- Where
- 33 sites in United States
- Sponsor
- Sequus Pharmaceuticals
Healthy Volunteers, HIV Infection
Safety Study Comparing a Vaccine Transcutaneous Administration to the Intramuscular Route
The rationale for transcutaneous vaccination is based on the unique ability of cutaneous immune cells, especially Langerhans cells (LCs), to present antigens to the immune system.
- Trial name
- MANON-05 (NCT00261001)
- Testing
- Transcutaneous mode of administration, Intramuscular mode of administration
- Where
- 2 sites in Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Objectif Recherche Vaccins SIDA
Human Immunodeficiency Virus, Cardiometabolic Risk
The Happy Older Latinos Are Active (HOLA) Health Promotion Study in HIV-Infected Latino Men
The purpose of this study is to examine the feasibility of an intervention to prevent chronic diseases like diabetes, high blood pressure, and obesity in midlife and older Latino adults living with HIV.
- Trial name
- HOLAHIV (NCT03839212)
- Testing
- HOLA Component 1, HOLA Component 2, HOLA Component 3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
HIV/AIDS
Packaging PrEP to Prevent HIV Among WWID
Evidence suggests women who inject drugs (WWID) are disproportionately vulnerable to HIV. If HIV incidence continues unchecked, 1 in 23 WWID in the United States will acquire HIV.
- Trial name
- NCT03304912
- Testing
- PrEP Education and option to accept a PrEP prescription
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Drexel University
Papillomatosis, HIV Infections
Treatment of Oral Warts in HIV+ Patients
This is a study to test lozenges of interferon-alpha that are dissolved in the mouth as a treatment of oral warts in HIV-positive adults.
- Trial name
- NCT00454181
- Testing
- Interferon-alpha
- Where
- 12 sites in United States
- Volunteers
- 59 people
- Sponsor
- Ainos, Inc. (f/k/a Amarillo Biosciences Inc.
HIV Infections
A Study to Evaluate Various Combinations of Anti-HIV Medications to Treat Early HIV Infection
The purpose of this study is to compare the effectiveness of various combinations of anti-HIV drugs in HIV-positive men and women.
- Trial name
- NCT00000919
- Testing
- Indinavir sulfate, Lamivudine/Zidovudine, Ritonavir
- Where
- 80 sites in United States, Italy and 1 more
- Volunteers
- 900 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV, Substance Abuse
Transitions: Linkages From Jail To Community
TRANSITIONS, a novel jail-release program for People Living with HIV/AIDS (PLWHA), will use evidence-based interventions and adapt them to create a comprehensive transitional program in Waterbury and New Haven County…
- Conditions
- HIV, Substance Abuse, HIV Infections
- Trial name
- NCT00841711
- Testing
- Intensive Case Management
- Where
- 2 sites in United States
- Volunteers
- 127 people
- Sponsor
- Yale University
Syphilis
Video Tool to Promote Knowledge of Syphilis as Facilitator of HIV Transmission
During the winter of 2007, the Syphilis Advisory Group and Bureau of STD Control of the NYC Department of Health funded the Emergency Department of Jacobi Medical Center to further evaluate the effectiveness of the Syphilis and…
- Trial name
- NCT00553111
- Testing
- educational video
- Where
- 2 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Jacobi Medical Center
HIV-1 Infection
4 Consecutive Days on Treatment Followed by 3 Days Off Treatment, in HIV Patients
Evaluate after 48 weeks, the capacity of a weekly strategy of 4 consecutive days on treatment followed by 3 days off treatment, in HIV-1 treated patients with undetectable viral load for at least 12 months and continuous…
- Trial name
- ANRS162-4D (NCT02157311)
- Testing
- Four consecutive days on treatment and 3 days off
- Where
- 17 sites in France
- Volunteers
- 100 people
- Sponsor
- ANRS, Emerging Infectious Diseases
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