Clinical trials: HPV InfectioN
Cervical Cancer Screening, HPV Infections
Cervical Cancer Screening of Postmenopausal Women in Low- and Middle-income Countries Using HPV Self-sampling and Triage by Genotyping and Cytology
Cervical cancer remains a major cause of mortality in low- and middle-income countries, especially among women aged 50 years and older who are often under-screened.
- Conditions
- Cervical Cancer Screening, HPV Infections, Cervical Intraepithelial Neoplasia
- Trial name
- NCT07244315
- Testing
- Vaginal specimens for HPV test will be collected by participants themselves using flocked swabs after explanations by co-investigators.
- Where
- Cameroon
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Cervical Cancer, Precancerous Condition
Knowledge and Perceptions About Human Papillomavirus and Cervical Cancer Risk Among Young Adults
RATIONALE: Learning about young adults' knowledge and perceptions about risk factors for the human papilloma virus and cervical cancer may help doctors learn more about how to prevent human papilloma virus infection and cervical…
- Trial name
- NCT00736216
- Testing
- survey administration
- Where
- 8 sites in United States
- Sponsor
- Case Comprehensive Cancer Center
Cervical Intraepithelial Neoplasia, Cervical Cancer
The Durability of Protection and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female
The primary objective of this study is to evaluate the durability of protection and immuno-persistence of Recombinant Human Papillomavirus Bivalent (Types 16,18) Vaccine administered in females aged 18-45 years.
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Vaginal Intraepithelial Neoplasia, Vulvar Intraepithelial Neoplasia
- Trial name
- NCT05045755
- Testing
- Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli)
- Where
- China
- Volunteers
- 1,339 people
- Sponsor
- Jun Zhang
HPV Infection, Cervix Cancer
Validation of Artificial Intelligence as Decision Support System in VIA (PRESCRIP-TEC)
The research project is a component of another research project that applies the protocol of the World Health Organization for screening of cervical cancer, with testing of high-risk Human Papilloma Virus (hrHPV) as first…
- Conditions
- HPV Infection, Cervix Cancer, Cervical Dysplasia
- Trial name
- AI-DSS (NCT06452004)
- Testing
- Validation of AI-DSS in Bangladesh, Validation of AI-DSS in Uganda, Validation of AI-DSS in India
- Where
- Uganda
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Genital Warts, Anal Cancer
Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003)
This study is designed to evaluate the immunogenicity and tolerability of 9vHPV (9-valent HPV vaccine, V503) in 16- to 26-year old men and women.
- Conditions
- Genital Warts, Anal Cancer, Anal Intraepithelial Neoplasia
- Trial name
- NCT01651949
- Testing
- 9vHPV Vaccine
- Volunteers
- 2,520 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Cancer of Cervix, Vaccinia
The Prospective Cohort Study to Evaluate the Preventive Efficacy of HPV Vaccine in Japanese Women Aged 27-45 Years
A nonrandomized, non-double blinded prospective cohort study to evaluate the preventive efficacy of quadrivalent HPV6/11/16/18 vaccine for the persistent infection of HPV16 genotype or HPV18 genotype in Japanese women aged 27-45…
- Trial name
- NCT04022148
- Testing
- Gardasil
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- University of Fukui
Viral Wart
Comparison of Therapeutic Efficacy Between Intralesional Bleomycin and Cryotherapy in Plantar Warts
A randomized control trial to compare the efficacy difference between intralesional bleomycin and cryotherapy in treating plantar warts.
- Trial name
- NCT05752435
- Testing
- COMPARISON OF THERAPEUTIC EFFICACY BETWEEN INTRALESIONAL BLEOMYCIN AND CRYOTHERAPY IN PLANTAR WARTS
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital Abbottabad
Cervical Intraepithelial Neoplasia, Cervical Cancer
Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m)
The primary objective of this study is to evaluate the immuno-persistence (type specific IgG antibody) of the tested vaccine administered in girls aged 9-17 years,comparing to young healthy adults of 18-26 years who received the…
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, Vaginal Intraepithelial Neoplasia, Vulvar Intraepithelial Neoplasia
- Trial name
- NCT04704908
- Testing
- Recombinant Human Papillomavirus Bivalent (Types 16, 18) Vaccine (Escherichia coli)
- Where
- China
- Volunteers
- 979 people
- Sponsor
- Jun Zhang
Cervical Intraepithelial Neoplasia, Human Papillomavirus Infection
HPV Genotyping by DR. HPV Genotyping in Vitro Diagnostic Device (IVD) Kit in Exfoliated Cells of the Uterine Cervix
High-risk type human papillomavirus (HPV) is the known etiological agent of cervical cancer. HPV testing and risk stratification by genotyping has been recognized as an effective cervical screening program.
- Conditions
- Cervical Intraepithelial Neoplasia, Human Papillomavirus Infection, HPV Infection
- Trial name
- NCT04333212
- Testing
- DR. Chip HPV genotyping IVD kit
- Where
- 4 sites in Taiwan
- Volunteers
- 1,103 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Anal Cancer, Nonneoplastic Condition
Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males
RATIONALE: Vaccines made from a gene-modified virus may help the body build an effective immune response to prevent viral infection.
- Conditions
- Anal Cancer, Nonneoplastic Condition, Penile Cancer, Precancerous Condition
- Trial name
- NCT01209325
- Testing
- quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine, laboratory biomarker analysis
- Where
- 19 sites in United States, Puerto Rico
- Volunteers
- 149 people
- Sponsor
- AIDS Malignancy Consortium
HSIL of Cervix, HSIL, High Grade Squamous Intraepithelial Lesions
Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.
This study evaluates the use of ABI-1968, a topical cream, in the treatment of cervical precancerous lesions in females without human immunodeficiency virus (HIV) infection.
- Conditions
- HSIL of Cervix, HSIL, High Grade Squamous Intraepithelial Lesions, High-Grade Cervical Intraepithelial Neoplasia, Human Papilloma Virus
- Trial name
- NCT03697226
- Testing
- Topical ABI-1968
- Where
- South Africa
- Volunteers
- 8 people
- Sponsor
- Antiva Biosciences
Infections, Papillomavirus
Gynaecological Follow-up of a Subset of HPV-015 (NCT00294047) Study Subjects
This study is intended to provide up to a maximum of four years of annual oncogenic human papillomavirus (HPV) DNA testing and cervical cytology examination for NCT00294047 study subjects who displayed normal cervical cytology…
- Trial name
- NCT01190176
- Testing
- Gynaecological follow-up, Cervarix
- Where
- 20 sites in United States, Canada and 5 more
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Neoplasms
Topical Curcumin for Precancer Cervical Lesions
The purpose of this study is to see if curcumin can reverse a cervical precancerous state by looking at people who have the condition and intervening with a study drug or placebo (an inactive drug), prior to planned therapeutic…
- Trial name
- NCT02944578
- Testing
- Curcumin
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Lisa Flowers
Vaccine Preventable Diseases, Meningococcal Disease
Testing the Use of Prompts to Increase Adolescent Immunization Rates
Although most US adolescents visit their primary care doctor, their immunization rates are low. Primary care practices from two networks, one in upstate New York as well as a national network of pediatric clinics were surveyed to…
- Conditions
- Vaccine Preventable Diseases, Meningococcal Disease, Human Papillomavirus, Pertussis
- Trial name
- AIMHi (NCT01984125)
- Testing
- Point-of-Care Prompt
- Where
- 22 sites in United States
- Volunteers
- 7,040 people
- Sponsor
- University of California, Los Angeles
Papillomavirus Infections, Oropharyngeal Neoplasms
E7 TCR Cell Induction Immunotherapy for Stage II and Stage III HPV-Associated Oropharyngeal Cancer
Background: The therapy used in this study is called E7 T-cell receptor (TCR) T cell therapy. This therapy is a type of treatment in which a participant's T cells (a type of immune system cell) are changed in the laboratory to…
- Trial name
- NCT04015336
- Testing
- E7 T-Cell Receptor (TCR)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute (NCI)
Cervical Cancer, Vulvar Cancer
Broad Spectrum HPV (Human Papillomavirus) Vaccine in 16 to 26 Year Old Women (V505-001)
The purpose of this study is to evaluate the safety and immunogenicity of V505 in comparison to GARDASIL (TM)
- Conditions
- Cervical Cancer, Vulvar Cancer, Vaginal Cancer, Genital Warts
- Trial name
- NCT00520598
- Testing
- Comparator: V505 formulation 1, Comparator: V505 formulation 2, Comparator: V505 formulation 3
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Anal Canal HPV Infection Diagnosis, Anal Dysplasia Diagnosis
Hybrid Capture 2 Human Papiloma Virus (HPV) High-Risk Anal DNA Test
This is a study to determine if HC2 HPV testing in the anal canal can detect high-risk HPV and whether this aids in identifying individuals are risk for anal cancer or precancerous lesions.
- Conditions
- Anal Canal HPV Infection Diagnosis, Anal Dysplasia Diagnosis, Anal Cancer
- Trial name
- NCT01104181
- Testing
- HC2 collection kit with a swab or brush
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Laser Surgery Care
HPV Infection, Vaccine Preventable Disease
Adding Male Single Dose HPV Vaccination to Female HPV Vaccination in Tanzania
Add-Vacc is an unblinded cluster-randomised trial (CRT) with two arms: (i) the national HPV vaccination programme (girls aged ~14 years, control arm) and (ii) the national programme plus single-dose male HPV vaccination given to…
- Trial name
- Add-Vacc (NCT04953130)
- Testing
- Gardasil® HPV vaccine
- Where
- Tanzania
- Volunteers
- 10,400 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Cervical Carcinoma, Human Papillomavirus Infection
HPV Self-Test Intervention in Ohio Appalachia
This study will pilot test a culturally appropriate human papillomavirus (HPV) self-test intervention among women from Ohio Appalachia in order to determine the feasibility of HPV self-testing as a potential cervical cancer…
- Trial name
- NCT02460237
- Testing
- Disease Screening, Educational Intervention, Informational Intervention
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Human Papillomavirus
Alinity m HR HPV Specimen Collection Study From Women Undergoing Routine Cervical Cancer Screening
A prospective multicenter interventional study will be conducted to enroll women undergoing routine cervical cancer screening to collect cervical liquid-based cytology (LBC) specimen(s).
- Trial name
- NCT04746872
- Testing
- Alinity m HR HPV
- Where
- 63 sites in United States
- Volunteers
- 14,935 people
- Sponsor
- Abbott Molecular