Clinical trials: HPV InfectioN
Infections, Papillomavirus
Safety Evaluation of a Human Papillomavirus (HPV) Vaccine in Healthy Female Control Subjects From the GSK HPV 023 Study
This phase IIIb study is designed to assess the safety of GlaxoSmithKline Biological's HPV vaccine GSK580299 in female subjects who took part in the HPV-023 (NCT00518336) study and received a placebo in the HPV-001 (NCT00689741)…
- Trial name
- NCT01418937
- Testing
- CervarixTM (GSK580299)
- Where
- 5 sites in Brazil
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Human Papillomavirus, Cervical Intraepithelial Neoplasia
Evaluating the 2-dose Immunization Schedule of Human Papillomavirus (HPV)-16/18 in Adolescent Females
To evaluate the immune non-inferiority, as measured by antibody responses, of a 2-dose immunization schedule (0, 6 months) of recombinant human papillomavirus virus-like particle vaccine (type 16 and 18 L1 proteins, yeast)…
- Conditions
- Human Papillomavirus, Cervical Intraepithelial Neoplasia, Persistent Infection
- Trial name
- NCT02740777
- Testing
- HPV-16/18 vaccine
- Where
- 2 sites in China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
HIV Infections, HPV-Related Cervical Carcinoma
Self-collected Vaginal and Urine Samples in HIV-positive Women
This study assesses topics as Human Immunodeficiency Virus (HIV), Human Papilloma Virus (HPV), and cancer screening methods. The focus will be on evaluating feasibility of implementing novel cancer screening modalities in a…
- Conditions
- HIV Infections, HPV-Related Cervical Carcinoma, Cervical Cancer, Coinfection, HIV
- Trial name
- NCT05783167
- Testing
- Self-sampling for HPV infection
- Where
- Guinea-Bissau
- Volunteers
- 502 people
- Sponsor
- University of Aarhus
Women's Health: Cervical Neoplasm
Mobile Outreach Screening of High-Risk Human Papillomavirus Infection in Women with Limited Access to Health Services in Seine-Saint-Denis (greater Paris Area, France)
The study is a prospective cervical cancer screening intervention in the nonclinical setting of a mobile testing unit in a vehicle, using point-of-care HPV PCR tests with self-collected vaginal swabs.
- Trial name
- PAPMOBILE (NCT06656611)
- Testing
- HPV self sampling
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
HPV Infection, Dysplasia Anus
Prevalence and Clinical Implications of HPV Infection in Male IBD Patients
The study aims at describing the prevalence of Human Papillomavirus (HPV) infection in anal and oral samples of men with Inflammatory Bowel Disease (IBD) and detecting risk factors for the infection.
- Conditions
- HPV Infection, Dysplasia Anus, Oral Cavity Disease
- Trial name
- PAPIMALE (NCT05911750)
- Testing
- Anal pap smear and oral swab for cytology and HPV testing
- Where
- Spain
- Volunteers
- 384 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cutaneous Warts
bLAC - Treatment of Cutaneous Warts in Immune Suppressed, Kidney Transplanted Patients
As many as 85 % of renal transplant patients may suffer from viral warts with a high degree of treatment resistance. Promising results of hLAC (human lactalbumin complex with lipid) point to a beneficial effect without noticeable…
- Trial name
- NCT00644579
- Testing
- bLAC
- Where
- 5 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- NatImmune A/S
Cervical Cancer, HPV Infection
Re-Evaluation of Annual Cytology Using HPV Testing to Upgrade Prevention in Women Living With HIV
Current British HIV Association (BHIVA) guidelines recommend annual cervical screening (with a cervical smear) for women living with HIV (WLWH). NHS guidelines for women in England will, however, change soon.
- Conditions
- Cervical Cancer, HPV Infection, HIV Infections
- Trial name
- REACH-UP (NCT04155294)
- Where
- 6 sites in United Kingdom
- Volunteers
- 71 people
- Sponsor
- University of Oxford
Condylomata Acuminata
Immunogenicity Study of the Recombinant Human Papillomavirus Virus Type 6/11 Bivalent Vaccine
This phase Ⅱ clinical study was designed to evaluate the immunogenicity and safety of the novel recombinant HPV type 6/11 bivalent vaccine, manufactured by Xiamen Innovax Biotech CO., LTD., in healthy volunteers aged 18-55 years…
- Trial name
- NCT02710851
- Testing
- low dosage HPV Vaccine(1:1), low dosage HPV Vaccine(1:2), high dosage HPV Vaccine(1:1)
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Jun Zhang
Cervical Cancer, DNA Methylation
Cervical Cytology DNA Methylation for Cervical Cancer Screening
Cervical cancer represents one of the foremost causes of cancer-related morbidity and mortality among women worldwide. Given the current limitations, such as the low specificity of human papillomavirus (HPV) testing and the…
- Conditions
- Cervical Cancer, DNA Methylation, Cytology, Human Papillomavirus Infection
- Trial name
- NCT06557954
- Testing
- human PAX1 and JAM3 gene methylation assays (PAX1m/JAM3m)
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- Lei Li
Cancer of Cervix, HPV Infection
The Effect of Education Given to Women on Cervical Cancer on Knowledge, Attitude and Belief
Aim: The aim of this study is to reveal the effect of education given to women about cervical cancer on knowledge, attitude and belief.
- Trial name
- EEWCCKAB (NCT05990270)
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Cervical Cancers, Vulvar Cancers
A Study of V503, a 9-valent Human Papillomavirus (9vHPV) Vaccine in Females 12-26 Years of Age Who Have Previously Received GARDASIL™ (V503-006)
This study will evaluate whether V503 (9vHPV vaccine), is well tolerated in girls and women between 12 and 26 years old who have previously been vaccinated with GARDASIL™.
- Conditions
- Cervical Cancers, Vulvar Cancers, Vaginal Cancers, Genital Warts
- Trial name
- NCT01047345
- Testing
- V503
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV Infections
A Clinical Trial to Evaluate the Immunogenicity of the Nonavalent Vaccine Against Human Papillomavirus in Men Infected by HIV Who Have Sex With Men. GESIDA 10017
Phase IV, open, multicenter and single-arm clinical trial designed to evaluate the immunogenicity of the HPV9v vaccine in men with HIV infection (HIV +) who have sex with men (MSM)
- Trial name
- GESIDA10017 (NCT03626467)
- Testing
- HPV9v
- Where
- 3 sites in Spain
- Volunteers
- 158 people
- Sponsor
- Fundacion SEIMC-GESIDA
Papillomavirus Infection
Acceptability of Human Papillomavirus Self-sampling in Women Living With HIV
Women living with HIV are unsufficiently screened for cervix cancer although they have a higher risk of developping it, resulting in many obstacles.
- Trial name
- AUTOCol (NCT05026047)
- Testing
- HPV self-sampling
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Infections, Anal Cancer
Screening for HIV-Associated Anal Cancer
Cancer of the anus occurs at very high rates in young men with HIV and is caused by a virus called human papillomavirus (HPV). Anal cancer has increased during the HIV epidemic despite effective therapies for HIV.
- Conditions
- HIV Infections, Anal Cancer, Anal Dysplasia, Papillomavirus Infections
- Trial name
- TRACE (NCT00188292)
- Where
- Canada
- Volunteers
- 401 people
- Sponsor
- University Health Network, Toronto
HPV Infection
Evaluation of the Prevalence of Oral HPV Infection in Patients Who Are Positive to the PAP-test
The present cross-sectional study aims to assess the prevalence and type distribution of oral HPV infection in PAP-test-positive women aged ≥18 years.
- Trial name
- NCT05949398
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Catania
Allogeneic Hematopoietic Stem Cell Transplant Recipient, Hematopoietic and Lymphoid Cell Neoplasm
Gardasil 9 Vaccine in Preventing HPV Infection in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant
This phase IV trial studies how well Gardasil 9 vaccine works in preventing human papillomavirus (HPV) infection in patients with hematologic malignancies who are undergoing donor stem cell transplant.
- Trial name
- NCT03023631
- Testing
- Recombinant Human Papillomavirus Nonavalent Vaccine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- M.D. Anderson Cancer Center
Human Papillomavirus Infection
Transmission Reduction and Prevention With HPV Vaccination (TRAP-HPV) Study
Human papillomavirus (HPV) is a member of the Papillomaviridae family of DNA viruses that is capable of infecting humans. HPV infection can cause cancers of the cervix, vulva, vagina, and anus in women or cancers of the anus and…
- Trial name
- TRAP-HPV (NCT01824537)
- Testing
- HPV vaccine, Gardasil 9, Hepatitis A vaccine
- Where
- Canada
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- McGill University
Infections, Papillomavirus
Drug Use Investigation for Cervarix®
This post-marketing study was designed to assess safety and efficacy of Cervarix® vaccine in Japanese female subjects under conditions of actual use.
- Trial name
- NCT01187927
- Testing
- Cervarix®
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HPV Infection, Anal Cancer
Identification of Molecular Signatures of High-risk Oncogenic HPV and Study of Their Associations With the Presence of High-grade Lesions and/or Anal Cancer 10 Years After Inclusion in the ANRS IPERGAY Trial
HPVsign is a cross-sectional, non-comparative, multicenter study involving all participants included in the HPV substudy of the ANRS IPERGAY trial.
- Trial name
- HPVsign (NCT06522256)
- Testing
- High-resolution anoscopy
- Where
- 3 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Cervical Cancer, Precancerous Condition
Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer form forming, growing, or coming back. Vaccines may help the body build an effective immune response against human papillomavirus and may be effective in…
- Trial name
- NCT00128661
- Testing
- human papillomavirus 16/18 L1 virus-like particle/AS04 vaccine, hepatitis A inactivated virus vaccine
- Where
- Costa Rica
- Volunteers
- 7,466 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline