Clinical trials: HPV InfectioN
Infections, Papillomavirus
Evaluation of Safety and Immunogenicity of Co-administering Human Papillomavirus (HPV) Vaccine With Other Vaccines in Healthy Female Subjects
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Vaccination of pre-teens and adolescents, ideally before sexual debut and thus before exposure to oncogenic HPV, is a…
- Trial name
- NCT00426361
- Testing
- Boostrix ® Polio, GSK Biologicals' HPV-16/18 L1 AS04 vaccine (Cervarix TM)
- Where
- 38 sites in France, Germany and 1 more
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HPV Infection
All-cause and Diseases-specific Mortality of High-risk HPV Infection
The corresponding prevention strategies and treatment routes of HPV infection can be provided through investigating causes of death due to HPV infection and specialized diseases.
- Trial name
- NCT06631495
- Testing
- Observation
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Papillomavirus Infections
Clinical Effectiveness of PAPILOCARE® in Regression of Cervix HPV Cytological Abnormalities (PAPILOBS GR).
The present study is a multicenter, open, non-interventional, prospective observational clinical study for the evaluation of the effectiveness of Papilocare® (medical device with CE mark) in the regression of cervix cytological…
- Trial name
- PAPILOBSGR (NCT06399341)
- Testing
- Papilocare vaginal gel
- Where
- 4 sites in Greece
- Volunteers
- 524 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Papillomavirus Infections
Efficacy, Immunogenicity, and Safety of V503 in Chinese Males (V503-052)
This study will evaluate the efficacy, immunogenicity, and safety of 9-valent human papillomavirus (9vHPV; V503) vaccine in Chinese men 20 to 45 years of age.
- Trial name
- NCT05285826
- Testing
- 9vHPV Vaccine
- Where
- 34 sites in China
- Volunteers
- 8,100 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HPV Infection, Cervical Cancer
Therapeutic Abstention and Surveillance of Intra-epithelial Histological Lesions of High Grade Cervical CIN2 (Cervical Intraepithelial Neoplasia Grade 2). SUIVICIN
This study proposes to describe and evaluate the rate of spontaneous regression of CIN2 at 2 year of follow up in women between 18 and 39 year old.
- Trial name
- SUIVICIN (NCT04057924)
- Testing
- abstention from CIN2 treatment and surveillance for at least 2 years
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bordeaux
High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion
Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities
The goal of this clinical trial is to learn if an investigational vaginal suppository therapy works to treat low-grade cervical lesions (ASC-US and LSIL) associated with high-risk human papillomavirus (hr-HPV) infection in women.
- Conditions
- High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion, ASC-US, HPV Infection
- Trial name
- NCT07572396
- Testing
- EGCG and Quinine Sulfate Vaginal Suppository
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- Amplexd Therapeutics, Inc.
HPV Infections, Cervical Cancer
Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years
This phase 3 study will evaluate the immunogenicity and safety of 9-valent HPV recombinant vaccine in Chinese females aged 9 to 45 years
- Conditions
- HPV Infections, Cervical Cancer, Vulvar Cancer, Vaginal Cancer
- Trial name
- NCT04895020
- Testing
- 9-valent HPV vaccine
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Cervical Cancer, Vulvar Cancer
Long-term Follow-up of Bivalent Human Papillomavirus (HPV) Vaccine Study in Women
This extension study aims to evaluate the long-term protection and immune response of the bivalent HPV vaccine in women aged 18-30 who participated in a previous efficacy study (311-HPV-1003).
- Conditions
- Cervical Cancer, Vulvar Cancer, Vaginal Cancer, CIN - Cervical Intraepithelial Neoplasia
- Trial name
- NCT06776055
- Testing
- HPV-16/18 vaccine
- Where
- 9 sites in China
- Volunteers
- 5,372 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Health Belief Model, Nursing Students
The Effect of Health Belief Model-Based HPV Infection and Vaccination Education on University Students' Knowledge and Health Beliefs
This study aimed to examine changes in knowledge and health beliefs (perceived susceptibility, severity, benefits, and barriers) regarding HPV infection and cervical cancer among students residing in a university dormitory…
- Conditions
- Health Belief Model, Nursing Students, HPV (Human Papillomavirus)-Associated
- Trial name
- NCT07900113
- Testing
- Educational intervention HPV
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Mersin University
HIV Infections, Condyloma Acuminata
The Safety and Effectiveness of Cidofovir in the Treatment of Venereal Warts in HIV-Infected Patients
To evaluate the safety and tolerance of topical cidofovir (HPMPC) therapy for condyloma acuminatum in patients with HIV infection.
- Trial name
- NCT00002327
- Testing
- Cidofovir
- Where
- 11 sites in United States
- Volunteers
- 40 people
- Sponsor
- Gilead Sciences
Human Papilloma Virus, Health Behavior
Health Belief Model Based Education on Human Papilloma Virus Infection and Vaccination
To evaluate impact of Health Belief Model Based Education on Human Papilloma Virus Infection and Vaccination among University Students
- Trial name
- NCT05175482
- Testing
- Virtual Education
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Marmara University
Anogenital Dysplasia
Ano-genital Human Papillomavirus (HPV) Infection, Precancerous Lesions and Genital Warts Among Danish Renal Transplant Recipients
Transplant-related malignancies have emerged as one of the important complications after organ transplantation. Some studies have shown that transplant recipients have an increased risk of developing cancer, especially…
- Trial name
- NCT03018327
- Where
- Denmark
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Infection
Immune Response to HPV Vaccine Among HIV-1-infected Subjects in Brazil
Besides the specific response to vaccine antigens, the investigators will analyze the anti-HPV immune response in HIV-1-infected men in different strata of immune deficiency.
- Trial name
- HPV (NCT02236234)
- Testing
- HPV vaccine
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Human Papillomavirus, Human Papillomavirus Infection
Human Papillomavirus in Young People Epidemiological Research 2 (HYPER2)
Australia was one of the countries to implement a universal school-based male vaccination program - in 2013. This research project will examine the prevalence of HPV among young men who have sex with men (MSM) who have been…
- Trial name
- HYPER2 (NCT03000933)
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Alfred
HIV Infections
Study of Human Papillomavirus Related Genital Pathology Among HIV Positive Women
This study is a Multicentre cohort study with inclusion throughout the full duration of the study. The primary objective is the study of human papillomavirus related genital pathology in HIV positive women.
- Trial name
- ANRS CO17 (NCT01311752)
- Testing
- surgical management of high grade lesions
- Volunteers
- 676 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Human Papillomavirus Infection, Genital Warts
The Epidemiologic Study of Human Papillomavirus Infection and Related Diseases
primary purpose:Evaluate the prevalence and incidence of HPV infection and related diseases in subjects. Secondary purpose:Analyze risk factors of HPV infection and related diseases.
- Trial name
- NCT02188004
- Where
- China
- Volunteers
- 4,691 people, healthy volunteers welcome
- Sponsor
- Jun Zhang
Common Wart
OM202JP Clinical Study of KNP2002
The goal of this clinical trial is to evaluate safety and efficacy of KNP2002 in patients with common warts aged 15 to 50 years old.
- Trial name
- NCT05896215
- Testing
- KNP2002
- Where
- 15 sites in Japan
- Volunteers
- 159 people
- Sponsor
- KinoPharma Inc.
HPV, HIV Infections
Gut and Vaginal Microbiota Profile Study for HIV Women
Women Living with HIV Infection （WLHIV）are intended to acquire HPV infection which usually contributes to variable cervical lesions.
- Conditions
- HPV, HIV Infections, Vaginal Microbiota
- Trial name
- NCT05996016
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Infection by Human Papilloma Virus
Dynamics of Human PApilloma Virus Interactions; Internet-based Students HeAlth Research Enterprise
Human papillomavirus (HPV) infection is the most common sexually transmitted infection. The high risk oncogenic types, HPV-16 and -18 are responsible for 70% of cervical cancers.
- Trial name
- DyPAVIR (NCT01988948)
- Testing
- Various biological sampling
- Where
- France
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Papillomavirus Infections
A Clinical Study of V503 in Chinese Females Who Have Previously Received a Bivalent Human Papillomavirus (HPV) Vaccine (V503-108)
Researchers want to learn if V503 (also called the 9-valent human papillomavirus [9vHPV] vaccine, recombinant) can induce an immune response to HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58 in Chinese females who previously…
- Trial name
- NCT07785843
- Testing
- V503
- Where
- China
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC