Clinical trials: HPV InfectioN
Human Papillomavirus Infection
APTIMA HPV 16 18/45 Genotype Assay on the TIGRIS DTS System in Women With ASC-US or Negative Pap Test Results
In both the ASC-US Study and Adjunct Study populations, the objectives are to: evaluate the performance characteristics of the AHPV-GT Assay for detecting cervical disease in women with APTIMA HPV Assay positive results and…
- Trial name
- AHPV-GT (NCT01384370)
- Where
- 3 sites in United States
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- Gen-Probe, Incorporated
Anogenital Warts, HIV Infection
Effectivity of Protein Purified Derivative Treatment for Anogenital Warts in HIV Patient
Warts are a common viral infection of the skin and are prevalent throughout the world, with an overall prevalence in the United States estimated at 2-20%.
- Conditions
- Anogenital Warts, HIV Infection, Tuberculin Purified Protein Derivative
- Trial name
- NCT06587542
- Testing
- Injection of protein purified derivative
- Volunteers
- 30 people
- Sponsor
- Universitas Padjadjaran
Cervical Carcinoma, Human Papillomavirus Infection
Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S01)
This clinical trial evaluates the use of self-collected vaginal samples for human papillomavirus (HPV) testing in patients referred for a colposcopy and/or cervical excisional procedures to improve cervical cancer prevention.
- Trial name
- SHIP-A-S01 (NCT06498661)
- Testing
- Biospecimen Collection, Cervical Biopsy, Colposcopy
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Genital Human Papilloma Virus Infection
AV2 Antiviral Spray Versus Placebo in Human Papillomavirus Cervix Infections
This study aims to prove that, by a one-time topical spray on the cervix, AV2-DM is an effective antiviral in reducing on short term (3 months) the human papillomavirus (HPV) infection.
- Trial name
- NCT01654822
- Testing
- topical application cervical spray, topical spray on the cervix, cervical swab with Cervex-Brush-Combi at T0
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Cesa Projects International
Human Immunodeficiency Virus, Human Papillomavirus
Feasibility of Intravaginal Artesunate as Adjuvant HPV & Cervical Precancer Treatment in Kenya
The objective of this randomized, placebo-controlled trial is to evaluate whether intravaginal artesunate pessaries (vaginal inserts) can be used as adjuvant therapy following thermal ablation to improve Human papillomavirus…
- Conditions
- Human Immunodeficiency Virus, Human Papillomavirus, Cervical Precancer
- Trial name
- NCT06519994
- Testing
- Artesunate vaginal inserts
- Where
- Kenya
- Volunteers
- 120 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Immunization, HPV Infection
Comparing Immune Response of 2 vs 3 HPV Doses (27-45 Years Old)
The goal of this clinical trial is to compare a 2-dose and 3-dose series of 9vHPV vaccine among 27-45-year-old females to assess if 2 doses elicit a noninferior immune response.
- Conditions
- Immunization, HPV Infection, Human Papillomavirus
- Trial name
- NCT05672927
- Testing
- 9-valent HPV vaccine, 2 doses alternate timing, 9-valent HPV vaccine, 3 doses standard timing
- Where
- United States
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Papilloma Viral Infection
A Study to Compare Immune Response of V503 to Gardasil in 16- to 26-year-old Men (V503-020)
Primary objective To demonstrate that administration of V503 induces non-inferior Geometric Mean Titres (GMTs) for serum anti-HPV 6, 11, 16, and 18, compared to GARDASIL in 16- to 26-year-old men
- Trial name
- NCT02114385
- Testing
- V503, GARDASIL
- Where
- 7 sites in Belgium, Germany and 1 more
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Anal Intraepithelial Neoplasia 2, Anal Intraepithelial Neoplasia 1
Anal Cancer and/or Precancer Screening: Performance Analysis of the BD Onclarity™ HPV Assay on Anal Specimens
Human papillomavirus (HPV) infection has been implicated as a necessary cause for the development of the majority of anogenital neoplasms which represent approximately 95% of anal tumors.
- Conditions
- Anal Intraepithelial Neoplasia 2, Anal Intraepithelial Neoplasia 1, Anal Cancer, High-Risk Cancer
- Trial name
- NCT06327568
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- European Institute of Oncology
Human Papillomavirus Infection, Anogenital Warts
Study of the Efficacy and Safety of the Drug Ingaron (Interferon-gamma) in the Treatment of Anogenital Warts
The primary purpose of this study is to evaluate the effectiveness of destructive therapy for anogenital warts in combination with the use of Ingaron in comparison with destructive therapy.
- Trial name
- ING-HPV-1 (NCT05156541)
- Testing
- Interferon gamma human recombinant (IFN-G)
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- SPP Pharmaclon Ltd.
Persistent HR-HPV Infection of the Cervix
Single-arm, Prospective Study of the Efficacy and Safety of Paiteling®Antibacterial Liquid in the Treatment of Persistent Cervical HR-HPV Infection
The effectiveness of Patellin ® antibacterial solution in treating persistent cervical HR-HPV infection
- Trial name
- NCT07493824
- Testing
- Patling ® Antibacterial Liquid
- Where
- China
- Volunteers
- 115 people
- Sponsor
- The First Hospital of Jilin University
Health Literacy, Human Papillomavirus (HPV) Infection
Comparing Digital and Collaborative Gamified Reinforcement Strategies for HPV Literacy and Retention Among Nursing Students
This randomized comparative study aims to evaluate the effectiveness of two gamified reinforcement strategies, Gimkit and Escape Room, on human papillomavirus (HPV) literacy, short-term retention, and gameful learning experiences…
- Conditions
- Health Literacy, Human Papillomavirus (HPV) Infection, Nursing Education
- Trial name
- NCT07667127
- Testing
- Escape Room-Based Gamified Reinforcement, Gimkit-Based Gamified Reinforcement
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Cervical Cancer, HPV Infection
HPV DNA Self-sampling in a General Practitioner's Office.
One of the limitations of organized cervical screening in the Czech Republic is the lack of participation in preventive gynecological examinations.
- Conditions
- Cervical Cancer, HPV Infection, Precancerous Lesion
- Trial name
- ASTRA (NCT06253169)
- Testing
- HPV DNA self-test
- Where
- 2 sites in Czechia
- Volunteers
- 2,000 people
- Sponsor
- Patient Organization Veronica
Infections, Papillomavirus
Study of Natural History of Human Papillomavirus (HPV) Infections in Adult Women With Recurrent Conizations in Norway
This is a register-based, epidemiological study of HPV type distribution in women aged 18 years and above with recurrent conization following a primary conization for high grade lesions/ microinvasive carcinomas.
- Trial name
- NCT00924794
- Testing
- Cancer Registry of Norway (database)
- Where
- Norway
- Volunteers
- 410 people
- Sponsor
- GlaxoSmithKline
Human Papillomavirus Infection
Anal HPV Infection and Risk for Anal High-grade Squamous Intraepithelial Lesion Among Thai MSM With Acute HIV Infection
1. To determine the prevalence and incidence of anal HSIL and associated risk factors among MSM who initiate ART during AHI.
- Trial name
- NCT03032575
- Testing
- SEARCH010/RV254
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Human Papillomavirus-Related Cervical Carcinoma
Single Dose of Cervarix Vaccine in Girls or Three Doses of Gardasil Vaccine in Women for the Prevention of Human Papillomavirus Infection, the PRIMAVERA-ESCUDDO Trial
This phase IIIb trial compares a single dose of the Cervarix vaccine in girls to 3 doses of the Gardasil vaccine in young women for the prevention of human papillomavirus (HPV) infection.
- Trial name
- PRIMAVERA (NCT03728881)
- Testing
- Quadrivalent Human Papillomavirus (types 6, 11, 16, 18) Recombinant Vaccine, Recombinant Human Papillomavirus Bivalent Vaccine
- Where
- Costa Rica
- Volunteers
- 1,240 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Papillomavirus Infections, Uterine Cervical Neoplasms
HPV Infection and Genital Microecology of Childbearing-age Female in China: A Cohort and Multicenter Study
The purpose of this study to access the relations between genital microecology, HPV infection and cervical intraepithelial neoplasia of childbearing-age female in China
- Conditions
- Papillomavirus Infections, Uterine Cervical Neoplasms, Sexual Transmitted Disease
- Trial name
- NCT04694495
- Testing
- 16S rRNA gene sequencing of cervical secretions
- Where
- 42 sites in China
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
HPV Infection, Infertilities
Evaluation of the Effect of a Dietary Supplement Based on EGCG, Vitamin B12, Hyaluronic Acid, and Folic Acid on the Maintenance of Physiological Balance and the Natural Defenses of the Male Genital System in Subjects Exposed to HPV Infection.
This is a randomized pilot interventional study aimed at evaluating the effect of a dietary supplement containing EGCG, vitamin B12, hyaluronic acid, and folic acid on the maintenance of physiological balance and natural defenses…
- Trial name
- PERVI-I (NCT07344337)
- Testing
- Pervistop
- Volunteers
- 96 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Warts
Gene Expression Of Suppressor Of Cytokines in In Cutaneous Warts
Warts are common epidermal growths caused by various strains of human papilloma virus (HPV). Viral warts are common with a prevalence rate of 7-12%.
- Trial name
- NCT05781841
- Testing
- Detection of expression of SOCS3 gene, Detection of expression of IFN-α gene, Detection of expression of IFN-β gene
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Human Papillomavirus Infection
Colposcopy Findings Among Women With High Risk HPV Other Than HPV 16/18 and Normal Cytology
Abnormal cervical cytology was the most common reason for women being referred to the colposcopy unit. We prospectively included the women with negative cytology (negative for intraepithelial lesions or malignancy (NILM)) and…
- Trial name
- NCT04369339
- Testing
- Colposcopy
- Volunteers
- 185 people
- Sponsor
- Bezmialem Vakif University
HPV Infection, HPV-Related Carcinoma
A Phase I Clinical Trial to Evaluate the Safety of 15-valent HPV Vaccine in Healthy Chinese People Aged 18-45 Years
To evaluate the safety and tolerability of 15-valent HPV vaccine in 9-45year-old participants.
- Conditions
- HPV Infection, HPV-Related Carcinoma, Genital Wart, HPV-Related Intraepithelial Neoplasia
- Trial name
- NCT06454175
- Testing
- 15-valent recombinant human papillomavirus vaccine (Hansenulapolymorpha)
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.