Clinical trials: HPV InfectioN
Human Papillomavirus Viruses
Epidemiology of Human Papillomavirus Infection Among Women Living on the Maroni and the Oyapock Rivers
Cervical cancer is the second most frequent cancer of women in French Guiana. Studies have shown that populations living in remote villages in the interior of the territory have early sexual relations and that multiple sexual…
- Trial name
- EPHaVI (NCT02895399)
- Testing
- Cervico-Vaginal Smears analysis
- Volunteers
- 643 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Human Papillomavirus, Uterine Cervical Neoplasms
An HPV Vaccine Provider Intervention in Safety Net Clinics
The purpose of this study is to develop, deliver and evaluate a provider intervention for mothers and their children to encourage receipt of the human papillomavirus (HPV) vaccine in the children and appropriate cervical cancer…
- Trial name
- NCT02808832
- Testing
- Educational materials
- Where
- United States
- Volunteers
- 806 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College
Recurrent Condyloma, Nonrecurrent Condyloma
Recurrent and Nonrecurrent Condyloma Treatment
Treatment is considered successful if the difference in the response in the reduction of the affected area is above 30% for any of the doses compared to placebo Patients will be randomised to 1 of 3 treatment arms 1. Placebo 2.
- Trial name
- NCT01639638
- Testing
- PROAPOPTOTIC PEPTIDE CIGB 300
- Where
- Argentina
- Volunteers
- 132 people
- Sponsor
- Laboratorio Elea Phoenix S.A.
HSIL, High Grade Squamous Intraepithelial Lesions, Anal Cancer
A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand
The purpose of this research is to assess the safety and effectiveness of circumferential radiofrequency ablation (RFA) to the anal canal using the BarrxTM Ablation System to destroy anal high-grade squamous intraepithelial…
- Conditions
- HSIL, High Grade Squamous Intraepithelial Lesions, Anal Cancer, HPV-Related Squamous Cell Carcinoma, Human Papilloma Virus
- Trial name
- NCT03302858
- Testing
- BARRX™ Anorectal Wand
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Stephen E. Goldstone
Infections, Papillomavirus
Human Papilloma Virus Vaccine Immunogenicity and Safety Trial in Young Adult Women With GSK Bio's Novel HPV Vaccine.
Human Papilloma viruses (HPV) are viruses that cause infections of the skin and genitals in men and women. Several types of HPV infection are transmitted by sexual activity and, in women, can infect the cervix (part of the uterus…
- Trial name
- NCT00231413
- Testing
- HPV 16/18 L1 AS04, HPV-16/18/31/45 L1 AS04 Formulation 1, HPV-16/18/31/45 L1 AS04 Formulation 2
- Where
- 11 sites in United States, Belgium
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cervical Precancer, Cervical Intraepithelial Neoplasia
Point of Care - Triage and Treatment for Cervical Pre-cancer
This study evaluates a modified two-probe thermal ablation protocol using the IRIS™ device and retrospectively assesses an AI-based Automated Visual Evaluation (AVE) triage algorithm among HPV-positive women in El Salvador.
- Conditions
- Cervical Precancer, Cervical Intraepithelial Neoplasia, Human Papillomavirus Infection
- Trial name
- POC (NCT07461818)
- Testing
- IRIS™ Thermal Ablation Device
- Where
- El Salvador
- Volunteers
- 5,000 people
- Sponsor
- Basic Health International, Inc.
HSIL, High-Grade Squamous Intraepithelial Lesions, Human Papilloma Virus Infection
Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection
This study evaluates the use of ABI-1968, a topical cream, in the treatment of anal precancerous lesions in adults with and without human immunodeficiency virus (HIV) infection.
- Conditions
- HSIL, High-Grade Squamous Intraepithelial Lesions, Human Papilloma Virus Infection, HIV Infection, Anal Cancer
- Trial name
- NCT03202992
- Testing
- ABI-1968
- Where
- 6 sites in United States, Australia
- Volunteers
- 57 people
- Sponsor
- Antiva Biosciences
Cervical Cancer, Cervical Intraepithelial Neoplasia
The Correlations Between HPV L1-Specific Immunologic Responses in Cervical Cancer and Cervical Intraepithelial Neoplasia (CIN) Patients and Their Prognosis
A. To investigate the relationship between serum titer of anti-HPV16 antibody and clinicopathological factors of cervical cancer patients. B.
- Trial name
- NCT00728871
- Testing
- peripheral blood isolation
- Where
- China
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
HPV Infection, Cervical Cancer
Clinical Correlation Between Self-collected and Physician-collected HPV Screening Kits
The objective of this study is to validate the of the Evalyn®Brush via self-collection to the standard clinician-collected technique using the BD SurePath™ collection vial and Rovers CombiBrush for detection of Human…
- Trial name
- NCT05679141
- Where
- Canada
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Switch Health Solutions Inc.
Chronic Kidney Disease, Stage IV (Severe), Chronic Kidney Disease, Stage V
The Study of Immunogenicity of Quadrivalent Vaccine Against Human Papilloma Virus (HPV) Types 6, 11, 16, and 18 (HPV-6/11/16/18) in Chronic Kidney Disease (CKD) Patients
Clinical trials have demonstrated the efficacy of HPV-6/11/16/18 vaccination (Gardasil. Merck) 3 doses at day 1, month 2, and month 6 to lower the occurrence of high-grade cervical intraepithelial neoplasia than did those in the…
- Trial name
- NCT01298869
- Testing
- HPV-6/11/16/18 vaccine
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Chulalongkorn University
Warts
Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment
The present study was set-up to evaluate clinical efficacy of Pixie® cryogenic pen versus two comparator cryogenic products (Wartner® and Wortie®) for the treatment of common and plantar warts.
- Trial name
- NCT03129373
- Testing
- Cryogenic treatment of warts
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Oystershell NV
Infections, Papillomavirus
A Study to Evaluate the Immunogenicity and Safety of GSK Biologicals' HPV Vaccine in Healthy Women Aged 18-35 Years
Human papillomavirus infection has clearly been recognized as the cause of cervical cancer. Indeed, the infection of the cervix by certain oncogenic types of HPV, if not cleared , can lead over time to cervical cancer in women .
- Trial name
- NCT00306241
- Testing
- HPV-16/18 L1 VLP AS04
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HPV Infection, Cervical Cancer
Non-Invasive Plasma Treatment for Cervical Infections: Targeting High- and Low-Risk HPV Variants
This is a prospective, single-center, observational proof-of-principle clinical trial at the Department of Women's Health of the University Hospital Tübingen.
- Trial name
- NCT06291311
- Testing
- Cold physical Plasma, Control group
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Tuebingen
Warts, Warts Hand
CellFX Comparison to Cryosurgery in Cutaneous Non-Genital Common Warts
This prospective, multicenter, single-blinded, randomized comparison study is designed to compare the safety and effectiveness of the CellFX System to Cryosurgery for the clearance of cutaneous non-genital common warts on all…
- Conditions
- Warts, Warts Hand, Verruca
- Trial name
- NCT04738734
- Testing
- CellFX System Device, Cryosurgery Liquid Nitrogen Sprayer
- Where
- 10 sites in United States
- Volunteers
- 150 people
- Sponsor
- Pulse Biosciences, Inc.
Condylomata Acuminata, Papillomavirus Infections
Safety and Efficacy Study of Topical Ranpirnase to Treat Genital Warts (HPV)
Ranpirnase in topical formulation is an antiviral drug being evaluated for the topical treatment of anogenital warts. The aims of this study is to evaluate the efficacy and safety of a topical formulation of ranpirnase in…
- Conditions
- Condylomata Acuminata, Papillomavirus Infections, Sexually Transmitted Diseases
- Trial name
- NCT02535104
- Testing
- Ranpirnase, Vehicle
- Where
- Bolivia
- Volunteers
- 70 people
- Sponsor
- Tamir Biotechnology, Inc.
Human Papillomavirus Infection
The Human Papillomavirus (HPV) Transmission Pilot Study
This transmission pilot study is a prospective study to determine feasibility of enrolling female partners into an international transmission study. Companion study to MCC-13930.
- Trial name
- NCT00823511
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
HPV Infection, Cervical Cancers
Remote Resilience: Novel Applications of mHealth in Nicaragua's Cancer Control Program
The goal of this clinical trial is to test an mHealth intervention for cervical cancer prevention in under-screened women ages 25-64 on the Caribbean Coast of Nicaragua.
- Trial name
- NCT06921798
- Testing
- mHealth
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Periodontal Disease, Gingivitis and Periodontal Diseases
Hippo Signaling Pathway Proteins in Gingival Crevicular Fluid of Individuals With Periodontal Disease
Periodontal disease is a chronic inflammatory condition of the tooth-supporting tissues in which the host inflammatory response drives the destruction of alveolar bone and periodontal attachment.
- Conditions
- Periodontal Disease, Gingivitis and Periodontal Diseases, Biomarker Discovery and Validation, Pathways
- Trial name
- BYHN-GCF-HIPPO (NCT07759466)
- Testing
- ELISA Biomarker Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anogenital Human Papilloma Virus Infection
3-year Immunogenicity Evaluation of Quadrivalent HPV Vaccine in China
The thirty-six-month immunogenicity evaluation of Quadrivalent HPV (Types 6, 11, 16, 18) L1 Virus-Like Particle (VLP) Vaccine in Chinese female subjects aged 9 to 45 years and male subjects aged 9 to 15 years.
- Trial name
- NCT01427777
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Guangxi Center for Disease Control and Prevention
Human Papillomavirus Infection
Colposcopy Findings Among Women With High Risk HPV Other Than HPV 16/18 and Normal Cytology
Abnormal cervical cytology was the most common reason for women being referred to the colposcopy unit. We prospectively included the women with negative cytology (negative for intraepithelial lesions or malignancy (NILM)) and…
- Trial name
- NCT04369339
- Testing
- Colposcopy
- Volunteers
- 185 people
- Sponsor
- Bezmialem Vakif University