Clinical trials: HPV Vaccination
Infections, Papillomavirus
Extension Study of the Efficacy of the GSK 580299 Vaccine in Japanese Women Vaccinated in the Primary NCT00316693 Study
This extension study is conducted to assess the efficacy of the GSK 580299 vaccine against cervical intraepithelial neoplasia (CIN) lesions, cervical cancer and cytological abnormalities associated with human papillomavirus…
- Trial name
- NCT00929526
- Testing
- Liquid-based cytology (LBC) sampling, Blood sampling
- Where
- 13 sites in Japan
- Volunteers
- 752 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HPV16 Positive, Cervical Intraepithelial Neoplasia (CIN 2/3)
Therapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3)
This study will test the efficacy and safety of different routes of administration of a DNA vaccine in patients with HPV16+ CIN2/3. Subjects will be enrolled in one of six treatment groups.
- Trial name
- NCT00988559
- Testing
- DNA vaccination, Gene gun vaccine, intramuscular vaccination
- Where
- 3 sites in United States
- Volunteers
- 132 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Cervical Cancer
The Combination of GX-188E Vaccination and Pembrolizumab in Patients With HPV 16 and/or 18+ Advanced Cervical Cancer
A Multi-Center, Open-label Phase Ib-II Trial of the Combination of GX-188E Vaccination and Pembrolizumab in Patients with Advanced, Non-Resectable HPV-Positive Cervical Cancer
- Trial name
- NCT03444376
- Testing
- GX-188E, KEYTRUDA®
- Where
- 9 sites in South Korea
- Volunteers
- 65 people
- Sponsor
- Genexine, Inc.
Vaccine, Human Papilloma Virus
HPV Message Testing and Social Media Campaign
This project involves a social media campaign to increase parent's knowledge and acceptance of the HPV (human papillomavirus) vaccine.
- Trial name
- NCT03747302
- Testing
- Social Media Message about HPV and HPV vaccine, Social media message about risk of electronic cigarettes.
- Where
- United States
- Volunteers
- 1,043 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Human Papillomavirus Infection
Randomized Trial of Alternative Quadrivalent Human Papilloma Virus (HPV) Vaccination Schedules in a University Setting
This is a randomized, open label trial of HPV (human papilloma virus) vaccine, comparing an on-time administration of the third dose with delayed administration of the third dose.
- Trial name
- NCT00572832
- Testing
- Quadrivalent human papillomavirus vaccine on-time administration, Quadrivalent human papillomavirus vaccine delayed administration
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
HPV Vaccination Decision Quality
Educational Intervention to Improve HPV Vaccination Decision Quality
The purpose of this study is to evaluate an innovative approach to improving HPV vaccination among the Hispanic population. The objectives/aims of this HPV educational intervention project are: 1.
- Trial name
- NCT02797054
- Testing
- Tailored educational materials, Untailored educational materials, Usual care
- Where
- United States
- Volunteers
- 1,205 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Immunization, Efficacy
GARDASIL 9: 3 Dose vs. 2 Dose With Delayed 3rd Dose
The investigators are evaluating whether 15-26 year old males and females need a 3rd dose of the human papillomavirus (HPV) vaccine, or whether 2 doses provide similar protection as 3 doses from the 9 types of HPV that it…
- Conditions
- Immunization, Efficacy, Human Papilloma Virus
- Trial name
- NCT03943875
- Testing
- 9-valent HPV vaccine, 2 dose efficacy, 9-valent HPV vaccine, 3 doses standard timing
- Where
- United States
- Volunteers
- 767 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
HPV Vaccine, HPV
Adaptation Of An HPV Education Resource To Promote HPV Vaccination
The purpose of the study is to assess Human Papillomavirus (HPV) and HPV vaccination knowledge, awareness, attitudes, health beliefs, and behaviors as well as educational preferences for learning more about HPV and HPV…
- Trial name
- NCT04974619
- Testing
- Online survey, Focus groups or Individual Interviews, Interviews
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Vaccination
Girls OnGuard: HPV Vaccination Uptake Among African American Adolescent Females
African American adolescent females seeking treatment for STIs are an underserved population at increased risk for HPV infection. While GARDASIL is an effective preventive vaccine, vaccination rates are low.
- Trial name
- Girls OnGuard (NCT00813319)
- Testing
- Girls OnGuard
- Where
- 2 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Emory University
Human Papillomavirus Vaccines
Developing a Self-persuasion Intervention Promoting Adolescent HPV Vaccination: Feasibility Trial
HPV vaccine coverage among adolescents in the US is suboptimal. This is particularly true among traditionally underserved adolescents. Few parent-targeted interventions have focused on the parental decision-making process.
- Trial name
- NCT02535845
- Testing
- Project Voice, HPV Informational Video
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Health Personnel Attitude, Health Knowledge, Attitudes, Practice
Healthcare Provider Human Papillomavirus Education and Professional Skills Intervention
Healthcare providers (HCP) serving the El Paso U.S.-Mexico Border Region will be recruited to compare educational and professional skills interventions focused on the human papillomavirus (HPV).
- Trial name
- NCT05120869
- Testing
- Tailored HPV Education and Professional Skills Intervention Group, General HPV Education and Communication Skills Control Group
- Where
- 2 sites in United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
HPV Vaccines
Effectiveness of SMS (Short Message Service) Text Messaging in Increasing Adherence to Gardasil
Human papillomavirus (HPV) is the most common sexually transmitted disease among adolescent females in the United States. Our primary objective is to determine if Short Message Service (SMS) text message reminders increase…
- Trial name
- CHAT (NCT01276184)
- Testing
- SMS Text Message
- Where
- 2 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
PRD (Paediatric Rheumatological Disease), IBD (Inflammatory Bowel Disease)
HPV Vaccination in Special Risk Groups: 5 Year Follow-up
In 2007-2009 the investigators conducted a study to determine the immunogenicity response to HPV vaccine in special risk patients known to be at increased risk of abnormal cervical cytology.
- Trial name
- NCT01896986
- Where
- Australia
- Volunteers
- 37 people
- Sponsor
- Murdoch Childrens Research Institute
Human Papilloma Virus Infection Type 11, Human Papilloma Virus Infection Type 16
HPV Vaccination: An Investigation of Physician Reminders and Recommendation Scripts
Primary, Secondary, and Exploratory Objective(s): Primary objective: To evaluate the effect of interventions on 1st dose uptake of HPV vaccine.
- Conditions
- Human Papilloma Virus Infection Type 11, Human Papilloma Virus Infection Type 16, Human Papilloma Virus Infection Type 18, Human Papilloma Virus Infection Type 6
- Trial name
- NCT02551887
- Testing
- Automated Reminder, Automated Reminder Plus Script
- Volunteers
- 647 people
- Sponsor
- Regenstrief Institute, Inc.
Vaccine Hesitancy
Increasing Vaccine Uptake Among Adolescents in the Rural South
The benefits of adolescent vaccines are well known for preventing meningococcal infection and human papillomavirus (HPV)-related pre-cancerous lesions.
- Trial name
- INVEST (NCT04999267)
- Testing
- INVEST
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Duke University
Cervical High Grade Squamous Intraepithelial Lesion
Randomized, Double Blind Trial of the Quadrivalent HPV Vaccine to Improve Responses to LEEP Treatment of Cervical HSIL
Cervical cancer occurs commonly in HIV-infected women in South Africa. These women have poor response to treatment of cervical cancer precursors.
- Trial name
- NCT01928225
- Testing
- Human Papillomavirus vaccine
- Volunteers
- 180 people
- Sponsor
- University of Witwatersrand, South Africa
Immunization Status, Well Child Care Visit
Evaluation of Vaccination Reminder/Recall Systems for Adolescent Patients
The investigators will design and implement a randomized clinical trial to test, on a community-wide level, the effectiveness of managed care based tracking/reminder/recall on improving vaccination coverage among adolescents.
- Trial name
- NCT01057888
- Testing
- Autodialer, Letters
- Volunteers
- 10,599 people
- Sponsor
- University of California, Los Angeles
HIV Positive, Anal Condylomata
The Effect of HPV Vaccination on Recurrence Rates in HIV Patients With Condylomata
The primary objective of this pilot study is to evaluate the effect of the HPV vaccine Gardasil on anal condylomata recurrence and persistence rates in HIV positive patients.
- Conditions
- HIV Positive, Anal Condylomata, Anal Warts, HIV Infections
- Trial name
- NCT00941889
- Testing
- Saline, Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recombinant Vaccine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Washington University School of Medicine
Cervical Cancer
An Intervention Study To Improve Human PapillomaVirus ( HPV) Immunization in Haitian and African American Girls
In the United States, Black women are more likely to die of cervical cancer than White women. In developing countries and globally, Haitian immigrant women are more likely to die of cervical cancer than any other women in the…
- Trial name
- HPV (NCT01254669)
- Testing
- BNI-brief Negotiated Interview
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Human Papillomavirus
Interactive, Health Literacy Promoting Text Messages and HPV Vaccine Completion In Minority Adolescents
Emerging communication technologies, such as text messaging offer low-cost, scalable opportunities to improve health literacy and promote healthy behaviors, such as vaccination.
- Trial name
- NCT02236273
- Testing
- Conventional text message reminder, Enhanced text message reminders
- Where
- United States
- Volunteers
- 956 people
- Sponsor
- Columbia University