Clinical trials: HRQOL (Health Related Quality of Life)
Health-related Quality of Life
The Impact of Supervision by a Health Care Professional on Quality of Life Questionnaire
Effect of supervision on scoring and completion on Quality of Life Questionnaire
- Trial name
- IMSUP (NCT06490393)
- Testing
- Questionnaires
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- St. Claraspital AG
Breast Cancer
Health-Related Quality of Life Coupled With Therapeutic Information on Compliance to Endocrine Therapy in Breast Cancer
Only 59% of women with breast cancer (BC) treated with Endocrine Therapy (ET) remain compliant one year upon initial prescription, despite its proven effectiveness in reducing recurrence and improving survival.
- Trial name
- COMPLIANCE (NCT04176809)
- Testing
- Routine Assessment of HRQoL coupled with Therapeutic Information
- Where
- France
- Volunteers
- 342 people
- Sponsor
- Centre Georges Francois Leclerc
Critical Illness
Cost Effectiveness Analysis of Critical Care in Resource Limited Setting
The purpose of this study was to examine the cost effectiveness of critical care in a middle income country with limited resources. The main study hypothesis was that critical care is cost effective in low resources setting.
- Trial name
- CEACCLR (NCT02556476)
- Testing
- mechanical ventilation, neuromuscular blockade, renal replacement therapy
- Volunteers
- 148 people
- Sponsor
- University of Sarajevo
Pain, Postoperative, Fractures, Closed
Cognitive Behavioural Therapy to Reduce Persistent Post-Surgical Pain After Fracture
Psychological factors such as stress, distress, anxiety, depression, and poor coping strategies may be associated with ongoing pain following injuries such as fractures.
- Conditions
- Pain, Postoperative, Fractures, Closed, Fractures, Open
- Trial name
- SPOC_CBT (NCT03196258)
- Testing
- Cognitive behavioural therapy
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- McMaster University
Endometriosis, Adenomyosis
Psychotherapy in Patients With Endometriosis: Cognitive Behavioral Therapy Versus Acceptance and Commitment Therapy
The aim of the present study is to compare two types of psychotherapeutic interventions in women with endometriosis and/or adenomyosis: cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT).
- Trial name
- T-ENDO (NCT07907848)
- Testing
- Cognitive Behavioral Therapy (CBT), Acceptance and Commitment Therapy (ACT)
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Fiammetta Cosci
Childhood Cancer Survivors
Lifestyle Medicine Adherence, Mental Wellbeing, and Quality of Life in Pediatric Oncology in Ecuador
Background: Advances in pediatric oncology have significantly improved survival rates; however, many children and adolescents with cancer experience persistent physical and psychological challenges that negatively affect their…
- Trial name
- NCT07490548
- Where
- 4 sites in Ecuador
- Volunteers
- 62 people
- Sponsor
- Universidad de Especialidades Espiritu Santo
Hepatitis C, Hemodialysis
Effect of HCV Infection on Insulin Resistance and Malnutrition-inflammation Complex Syndrome in Regular Hemodialysis Patients
The purpose of this study is to study whether hepatitis C virus (HCV)infected maintenance hemodialysis (MHD)patients have distinct metabolic, inflammatory and adipokine characteristics that can be linked to poor clinical outcome…
- Conditions
- Hepatitis C, Hemodialysis, Quality of Life, Mortality
- Trial name
- NCT00527774
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- St. Martin De Porress Hospital
Post Surgical Pain
Patient-reported Outcomes of Postsurgical Pain and Health Related Quality of Life
This study will investigate the impact of post-surgical pain (PSP) on health related quality of life (HRQoL) within the first six months following surgery using patient-reported outcome (PRO) measures, and to investigate medical…
- Trial name
- HRQoL (NCT03926858)
- Where
- 23 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Peking University People's Hospital
Primary Breast Cancer
Large Language Model-Based Emotional Management for Breast Cancer Patients
This study (study type: randomized controlled trial) aims to evaluate whether a large language model-based precision emotional management intervention can improve health-related quality of life among patients with primary breast…
- Trial name
- EMBRACE (NCT07452055)
- Testing
- Large Language Model-Based precision emotional intervention system, Usual Care Group
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Dentin Hypersensitivity, Quality of Life
Validation of a French Version of the DHEQ
Dentin hypersensitivity (DH) results in brief, sharp pain in response to a stimulus. It often seems to be underdiagnosed but also undertreated due to the lack of consensus on the topic.
- Trial name
- DHEQ-VALID (NCT06466200)
- Testing
- Schiff Test, GOHAI questionnaire, OHIP questionnaire
- Where
- 3 sites in France
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
COVID-19, SARS-CoV-2 Infection
Physical and Cognitive Impairments in People Suffering From Long COVID
Of the 1,900,000 Canadians who have been infected by COVID-19, 8 to 15% will continue to experience COVID-19 related symptoms well after 12 weeks. The persistence of such symptoms is now defined as "long COVID" syndrome.
- Conditions
- COVID-19, SARS-CoV-2 Infection, Corona Virus Infection, Physical Disability
- Trial name
- NCT05216536
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Laval University
Tooyh Discoloration
Impact of At-Home Dental Bleaching on Quality of Life Using OHIP-14
This prospective clinical study aims to evaluate the clinical efficacy of an at-home dental bleaching protocol and its impact on oral health-related quality of life using objective color measurements and patient-reported…
- Trial name
- WID-OHIP (NCT07624344)
- Testing
- Carbamide peroxide 16%
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Rectal Cancer, Colon Cancer
Assessment of Health Related Quality of Life in Patients Treated for Rectal Cancer
Treatment of rectal cancer often consists of surgical resection of the tumor. Chemotherapy and/or radiotherapy are frequently given before or after surgery.
- Conditions
- Rectal Cancer, Colon Cancer, Anal Cancer
- Trial name
- NCT00532987
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Stanford University
Quality of Life
Quality of Life in Children With Psychiatric Disorders and Parental Well-being: Effects of Group CBT
This study examines the immediate and long-term effectiveness of a group cognitive behavioral therapy intervention (GCBT) in improving health-related quality of life (HRQOL) in children treated for mixed psychiatric disorders in…
- Trial name
- NCT05808114
- Testing
- Friends program, TAU
- Volunteers
- 109 people
- Sponsor
- Helsinki University Central Hospital
DIPG, Brain Tumor, Pediatric, Recurrent
HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers
Although many children with brain tumours are successfully cured of their disease, a substantial proportion of patients suffer disease recurrence and require further treatment.
- Conditions
- DIPG, Brain Tumor, Pediatric, Recurrent, Brain Tumor, DIPG, Radiation Toxicity
- Trial name
- NCT04670016
- Testing
- This study does not include an intervention.
- Where
- 13 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Heart Failure，Congestive
Personal Decision Support System for Heart Failure Management
Despite the availability of evidence-based guidelines for disease management in patients with congestive heart failure (CHF), the uptake of these guidelines in clinical practice is sub-optimal and adherence rates are…
- Trial name
- HeartMan (NCT05651698)
- Testing
- HeartMan Intervention group
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 79 people
- Sponsor
- University Ghent
Colorectal Cancer
Advanced Geriatric Evaluation and Quality of Life in Colorectal Cancer Surgery
Colorectal cancer (CRC) disproportionately affects patients aged 70 years and older. Surgery is the main treatment modality for CRC, but is associated with increased risk of postoperative morbidity, disability and loss of health…
- Trial name
- AGE CRC (NCT04443816)
- Where
- 6 sites in Netherlands
- Volunteers
- 273 people
- Sponsor
- St. Antonius Hospital
End-Stage Kidney Disease, Peritoneal Dialysis
Nocturnal APD vs. CAPD in Non-diabetic ESKD
Background: Continuous ambulatory peritoneal dialysis (CAPD) imposes a substantial daytime burden. Nocturnal automated peritoneal dialysis (APD) may improve patient-centered outcomes, but high-quality evidence is lacking.
- Trial name
- NCT05449067
- Testing
- Nocturnal automated peritoneal dialysis (APD), Continuous Ambulatory Peritoneal Dialysis (CAPD)
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Medication-related Problems, Self-reported Medication Adherence
Improving Medication Therapy Through a Digital Interdisciplinary Medicine Therapy Optimisation Model
In this study, a telepharmacy service in primary care for home-living older adults in Northern Sweden's rural areas will be developed and evaluated.
- Conditions
- Medication-related Problems, Self-reported Medication Adherence, Health-related Quality of Life, Beliefs About Medicines
- Trial name
- MTO (NCT05629936)
- Testing
- Telepharmacy service
- Where
- 2 sites in Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Umeå University
Tooth Loss
Removable Partial Dentures Made of PEEK
As part of the clinical study, 25 patients each were provided with removable partial dentures with clasps made of PEEK in two centres (University Hospital Heidelberg, Department of Prosthodontics and University Hospital for…
- Trial name
- KLAP (NCT06191107)
- Testing
- Removable Partial Denture
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
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