Clinical trials: Haemodialysis
Uremic Pruritus
A Randomized-Withdrawal Phase 3 Study Evaluating the Safety and Efficacy of Oral Nalfurafine HCl (AC-820)in Subjects on Hemodialysis With Uremic Pruritus (Renal Itch)
Primary objective of this multicenter, double-blind, placebo controlled, randomized withdrawal study are to determine the effectiveness and safety of orally administered AC-820 in doses of 2.5 µg and 5.0 µg daily in patients with…
- Trial name
- AC120-8231 (NCT00793156)
- Testing
- Nalfurafine HCl 2.5 µg, Nalfurafine HCl 5.0 µg
- Volunteers
- 350 people
- Sponsor
- Acologix, Inc.
Peripheral Arterial Disease, Fistula
A Study of Hemodialysis Arteriovenous Fistulae Stenosis Treated With APERTO
To evaluate the safety and efficacy of Paclitaxel Eluting Hemodialysis Shunt Balloon Dilatation Catheter (APERTO) compared with the Balloon Dilatation catheter (OHICHO II) for the treatment of Arteriovenous Fistulae Stenosis in…
- Trial name
- NCT02962141
- Testing
- Paclitaxel Releasing Peripheral Balloon Dilatation Catheter, Balloon Dilatation Catheter
- Where
- 9 sites in China
- Volunteers
- 161 people
- Sponsor
- ZhuHai Cardionovum Medical Device Co., Ltd.
End Stage Renal Disease, Acute Kidney Injury
Immunomodulatory Biomimetic Device to Treat Myocardial Stunning in End-stage Renal Disease Patients
Hemodialysis is a therapy that filters waste, removes extra fluid and balances electrolytes. In hemodialysis, blood is removed from the body and filtered through a man-made membrane called a dialyzer, and then the filtered blood…
- Conditions
- End Stage Renal Disease, Acute Kidney Injury, Chronic Kidney Disease Stage 5
- Trial name
- ESRD (NCT03539861)
- Testing
- Hemodialysis
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Michigan
Metabolic Syndrome, Dialysis; Complications
Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients
This prospective, multicenter, cross-sectional, repeated-measures comparative study compared functional and biochemical response profiles to exercise between 2 groups of chronically ill patients (chronic renal failure dialysis…
- Trial name
- KREBSome-IRC (NCT06360302)
- Testing
- Exercise test, Blood sample, Impedancemetry
- Where
- 2 sites in France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Hemodialysis, Intradialytic Hypotension
Different Ultrafiltration Rates and Intradialytic Hypotension.
Finding relationship between different ultrafiltration rates and intradialytic hypotension in attempt to find the optimal cut off points.
- Trial name
- NCT06695923
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Kidney Disease
Arterial Calcifications in Nocturnal Hemodialysis and Renal Transplantation Versus Conventional Dialysis
Objective: 1. To assess whether nocturnal hemodialysis and renal transplantation are associated with less progression of coronary arterial calcification, compared with conventional hemodialysis and peritoneal dialysis; 2.
- Trial name
- NOCTX (NCT00950573)
- Where
- 2 sites in Netherlands
- Volunteers
- 184 people
- Sponsor
- Dianet Dialysis Centers
Chronic Kidney Disease-Associated Pruritus in Hemodialysis
Clinical Study on the Efficacy and Safety of Nalfurafine Hydrochloride Orally Disintegrating Tablets in Treating Pruritus in Patients Undergoing Maintenance Hemodialysis
This is a randomized, open-label, multi-center clinical study aimed at evaluating the efficacy and safety of 12 weeks of nalfurafine hydrochloride administration in the treatment of pruritus in patients undergoing maintenance…
- Trial name
- NCT07650851
- Testing
- Nalfurafine Hydrochloride, Basic treatment
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese PLA General Hospital
End Stage Renal Disease, Renal Anemia
Assessment of an Anemia Model Predictive Controller for Anemia Management in Hemodialysis Patients
The purpose of this randomized, controlled pilot study is to evaluate the performance of this novel Anemia Controller (vis-à-vis standard of care) for anemia management in hemodialysis patients.
- Conditions
- End Stage Renal Disease, Renal Anemia, Chronic Kidney Diseases
- Trial name
- NCT04360902
- Testing
- Anemia Controller
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Renal Research Institute
End Stage Renal Disease
Study to Evaluate the Performance and Safety of Expedial and Compare it to Expanded Polytetrafluoroethylene (ePTFE) Vascular Access Grafts
The purpose of this study is to establish the substantial equivalence of Expedial and ePTFE grafts for effectiveness in maintaining primary or assisted primary patency.
- Trial name
- NCT00131872
- Testing
- Expedial Vascular Access Graft
- Where
- 8 sites in United States
- Volunteers
- 172 people
- Sponsor
- LeMaitre Vascular
Anemia of Chronic Kidney Disease
Comparison Study of Two Iron Compounds for Treatment of Anemia in Hemodialysis Patients
Patients with end-stage kidney disease on maintenance hemodialysis frequently require iron supplementation to compensate for ongoing iron losses, and to maintain hemoglobin levels with or without additional use of…
- Trial name
- COPEFER (NCT02198495)
- Testing
- Supplementation of ferric carboxymaltose, Supplementation of iron sucrose
- Where
- 2 sites in Austria
- Volunteers
- 143 people
- Sponsor
- Medical University of Vienna
End Stage Renal Disease
Treatment Modification to Reduce Symptom Burden in Hemodialysis
Many patients on hemodialysis experience high rates of symptom burden, such as pain, depression, anxiety and difficulty breathing.
- Trial name
- NCT01775800
- Testing
- Treatment modification
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Rogosin Institute
Sudden Cardiac Death
Exercise and Cardiac Measures in Dialysis Patients
Background: The impact of the known non-invasive cardiac indices for identification of hemodialysis (HD) patients at high-risk for sudden cardiac death (SCD) has not been evaluated.
- Trial name
- NCT00944775
- Testing
- Exercise training
- Where
- Greece
- Volunteers
- 63 people
- Sponsor
- Aristotle University Of Thessaloniki
End-stage Renal Disease
Study of High Sensitive Troponin-I Level in End-stage Renal Disease Patients Receiving Hemodialysis
This study objective is to compare the high sensitive troponin-I level in end-stage renal disease patients received hemodialysis without acute cardiovascular event with healthy population.
- Trial name
- NCT02572466
- Testing
- Hemodialysis
- Where
- Thailand
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Inflammation, Body Composition
Influence of Nutritional and Inflammational Status on Survival of Hemodialysis Patients
prospective longitudinal measurements of nutritional status parameters (body composition by BIA, anthropometry and biochemical indexes), inflammatory response (CRP, inflammatory cytokines (IL-1, IL-6, IL-10),IGF-1, leptin and NOx…
- Trial name
- NCT00410137
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Sarcopenia, Renal Insufficiency, Chronic
Exercise During Hemodialysis: Impact on Sarcopenia and Sleep Quality
Sarcopenia (the loss of muscle mass, strength, and function) is highly prevalent in patients with Chronic Kidney Disease (CKD) undergoing hemodialysis, significantly increasing the risk of falls, frailty, and mortality.
- Trial name
- NCT07447375
- Testing
- Intradialytic Personalized Exercise Program.
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- University of Salamanca
End Stage Renal Disease, Chronic Kidney Disease
Palm Tocotrienols in Chronic Hemodialysis (USA)
Patients undergoing chronic hemodialysis are at increased risk for cardiovascular disease, attributed in part to increased oxidative stress, inflammation and dyslipidemia.
- Trial name
- PATCH (NCT02358967)
- Testing
- TRF (Tocotrienol-rich-fraction)
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Wayne State University
Dialysis, Anemia
Study of Roxadustat (FG-4592) to Correct Anemia in Newly Initiated Dialysis Participants Not on Erythropoiesis-Stimulating Agent Treatment
The purpose of this study is to evaluate efficacy and safety of roxadustat in the correction of anemia in participants with end-stage renal disease who recently started dialysis.
- Trial name
- NCT01414075
- Testing
- Roxadustat, Oral Iron, IV Iron
- Where
- 7 sites in United States, Hong Kong and 2 more
- Volunteers
- 60 people
- Sponsor
- Kyntra Bio
Hemodialysis Complication, Infectious Disease
Is Cefazolin, Ceftazidime and Ciprofloxacin Dosing Optimal in Hemodialysis Patients?
This study aims to optimize the dosing of cefazolin, ceftazidime, and ciprofloxacin for patients on high-flux hemodialysis. For each antibiotic 20 participants will be enrolled and three blood samples will be collected from each…
- Conditions
- Hemodialysis Complication, Infectious Disease, End Stage Renal Disease
- Trial name
- NCT04319328
- Testing
- Cefazolin, Ceftazidime
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Chronic Renal Failure, Hemodialysis
Comparing the Hemodiafiltration On-line and Conventional Hemodialysis in Terms of Cost-benefit
The site where the clinical trial will be conducted is at the St-Luc hospital from the CHUM. This is a prospective randomized study that will compare the two treatment modalities, HD and HDF, through economics and…
- Trial name
- PHARMACO-$ (NCT02374372)
- Testing
- conventional hemodialysis, hemodiafiltration On-line
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Chronic Renal Failure Patients With Hyperphosphataemia Receiving Hemodialysis
Post-marketing Surveillance of Kiklin Capsules in Hemodialysis Patients
The purpose of this survey is to evaluate the safety and efficacy of long-term use of Kiklin® Capsules in actual clinical settings.
- Trial name
- NCT01901107
- Testing
- Kiklin capsules
- Where
- 8 sites in Japan
- Volunteers
- 1,078 people
- Sponsor
- Astellas Pharma Inc