Clinical trials: Haemodialysis
End-Stage Renal Disease Requiring Haemodialysis, Hemodialysis Access Failure (Disorder)
BONE ANCHORED PORT for Hemodialysis Treatment
A Bone Anchored Port System (BAP) will be implanted in the mastoid bone behind the ear, connected with a double lumen central venous catheter inserted in the jugular vein, and will be used in conjunction with an adapter as a…
- Trial name
- BAP (NCT02069860)
- Testing
- Bone Anchored Port System (BAP)
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- Cendres+Métaux
Haemodialysis, Uremic Pruritus
A Study of Thalidomide in the Treatment of Refractory Uremic Pruritus
The purpose of this study is to evaluate the safety and efficacy of thalidomide in the treatment of refractory uremic pruritus in maintenance hemodialysis patients.
- Conditions
- Haemodialysis, Uremic Pruritus, Thalidomide
- Trial name
- NCT05525234
- Testing
- Thalidomide
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
End Stage Renal Disease, Haemodialysis
Comparison of Citrate and Heparin Anticoagulation During Hemodialysis With MCO PES-PVP (Theranova) Membrane
The purpose of the study is to compare the efficiency and biocompatibility of citrate and heparin anticoagulation during hemodialysis with medium cut-off polyarylethersulphone-polyvinylpirrolidone membrane (Theranova®).
- Conditions
- End Stage Renal Disease, Haemodialysis, Anticoagulation
- Trial name
- NCT04139525
- Testing
- unfractionated heparin, 8% trisodium citrate
- Where
- Slovenia
- Volunteers
- 32 people
- Sponsor
- Marija Malgaj Vrečko
End Stage Renal Disease, Haemodialysis
Combination of Medium Cut-off Dialyzer Membrane and Diet Modification to Alleviate Residual Uremic Syndrome of Dialysis Patients
The study will compare achieved levels of protein-bound uremic toxins with dialysis using a medium cut-off membrane compared to the treatment by online haemodiafiltration with a high-flux dialysis membrane.
- Conditions
- End Stage Renal Disease, Haemodialysis, Diet, Healthy
- Trial name
- NCT04247867
- Testing
- medium cut-off (MCO) dialysis membrane, Dietary fiber mixture (Plantago Psyllium and Inulin), Sodium propionate
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
End Stage Renal Disease, Haemodialysis
The Effect of Combining Medium Cut Off Dialysis Membrane and Diet Modification on Reducing of Inflammation Response
The investigators purpose is to research the impact of the simultaneous use of a new dialysis membrane with higher permeability for medium and protein bound uraemic toxins (medium cut-off dialysis membrane Theranova®) combined…
- Conditions
- End Stage Renal Disease, Haemodialysis, Diet, Healthy, Chronic Inflammation
- Trial name
- NCT04260412
- Testing
- medium cut-off (MCO) dialysis membrane, Dietary fiber mixture (Plantago Psyllium 69% and Inulin 30%), Sodium propionate
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Kidney Failure, Haemodialysis Fluid Adverse Reaction
BIS-guided Fluid Management in HD Patients
Hemodialysis (HD) is life-sustaining in kidney failure. However, adequate fluid status depends on precise estimation of dry weight (DW), which is a goal difficult to achieve.
- Trial name
- NCT05272800
- Testing
- Spectroscopy Bioimpedance Analysis, Clinical Examination alone
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Catholic University of Pelotas
Renal Failure Chronic Requiring Hemodialysis, Haemodialysis-induced Symptom
Mechanisms of Intradialytic Hypertension
Patients with end-stage renal disease (ESRD) are at significantly higher risk for death due to cardiovascular disease. Those with paradoxical increases in blood pressure (BP) during hemodialysis (HD), defined as intradialytic…
- Conditions
- Renal Failure Chronic Requiring Hemodialysis, Haemodialysis-induced Symptom, Hypertension
- Trial name
- MID-H (NCT01947673)
- Testing
- Mindfulness Meditation, Health Education
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Emory University
Anaemia, Haemodialysis
Treatment Response in Dialysis Anaemia
Anaemia in dialysis patients requires treatment with frequent dose adjustments. There are two current possible treatments for anaemia which are iron and erythropoietin stimulating agents (ESA).
- Trial name
- PRIME (NCT02707757)
- Testing
- Iron sucrose, Erythopoietin stimulating agent
- Where
- 2 sites in United Kingdom
- Volunteers
- 197 people
- Sponsor
- Imperial College Healthcare NHS Trust
Haemodialysis
Ultrasound Guided Cannulation of Dialysis Fistulas
The investigators suspect that using ultrasound to guide insertion of needles for dialysis patients will make this process quicker and more accurate, thus reducing complications and reducing discomfort for patients.
- Trial name
- NCT01163981
- Testing
- Use of ultrasound guidance in cannulation
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- University of Hull
Chrnoic Haemodialysis Patients
Muscle Mass or Muscle Function as a prédictive Tools for Outtcomme in Chronic Dialysis Patients
Aim of this study is to compare the association of muscle mass and functionality with mortality among chronic haemodialysis the involvement of malnutrition inflammation and atherogenesis syndrome (increase in C reactive protein…
- Trial name
- NCT03845452
- Where
- France
- Volunteers
- 187 people
- Sponsor
- University Hospital, Montpellier
Haemodialysis-induced Symptom
Cerebral Blood Flow During Hemodialysis
The purpose of this study is to evaluate the effect of the hemodialysis procedure on cerebral blood flow (CBF) in elderly maintenance hemodialysis (HD) patients.
- Trial name
- NCT02272985
- Testing
- [15O]H2O PET-CT scan, NIRS (Invos)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Haemodialysis Complication
Combining Bioimpedance and Blood Volume Measurements in Haemodialysis
Around 60,000 patients in the UK are being treated for severe kidney failure. The most common treatment is haemodialysis (HD). An important part of HD is removing extra fluid from the body which the kidneys normally remove in…
- Trial name
- NCT03851185
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Haemodialysis Complication
Cooler Dialysis and Liver Perfusion and Function
Having hemodialysis affects the blood supply to various organs in the body including the heart and the brain. With time, these effects build up and can affect the way these organs function.
- Trial name
- NCT02997774
- Testing
- Cooler dialysis, Standard Dialysis
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Chris McIntyre
Children, Haemodialysis
Haemodiafiltration vs Conventional Haemodialysis in Children
Children on conventional haemodialysis (HD) die of heart disease. Also, they can be malnourished and short. Haemodiafiltration (HDF) is a newer type of dialysis that achieves better removal of toxins and excess fluid than HD.
- Conditions
- Children, Haemodialysis, Haemodiafiltration
- Trial name
- 3H (NCT02063776)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Haemodialysis
Epidemiologic Study and Impact Study of a Dialysis Solution Change on the Electrocardiographic Profile of Patient
Epidemiologic Study and Impact Study of a Dialysis Solution Change on the Electrocardiographic Profile of Patient
- Trial name
- QT_DIAL (NCT02887742)
- Where
- 2 sites in France
- Volunteers
- 57 people
- Sponsor
- University Hospital, Brest
Haemodialysis Complication, Immune Dysfunction
T Regulatory Cells in Hemodialysis Patients: Observational Study
In this observational study, the investigators evaluated the Treg number and function in a population of patients undergoing hemodialysis (HD).
- Trial name
- NCT02981992
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Haemodialysis
Evaluation of the Validity of the Prothrombin Time Internation Normalised Ratio (PT/INR) Measured at the point-of Care on the Arterial Bloodline of Haemodialysis Extracorporeal Blood Flow
The purpose of this study is to evaluate the INR value of hemodialyzed patient coagulation state (prothrombin time) measured inside the therapeutical zone and thanks to a portable monitor.
- Trial name
- COAGHEMO (NCT02902848)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Adult Chronic Haemodialysis Patients Since at Least 3 Months
Heparin Free Haemodialysis With Haemodialyzers "VIE" Versus "EVODIAL"
The adequate anti coagulation is an absolute necessity in order to avoid the extra-corporal circuit and haemodialyzer clotting and to perform an adequate renal replacement therapy during a haemodialysis session.
- Trial name
- NCT01221337
- Testing
- heparin free haemodialysis
- Where
- 2 sites in France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Patients With Impaired Renal Function and Haemodialysis
ASP8825 - Pharmacokinetics Study in Patients With Impaired Renal Function and Haemodialysis
The objective of this study is to evaluate the pharmacokinetics and safety of ASP8825 in patients with impaired renal function and haemodialysis.
- Trial name
- NCT02629224
- Testing
- ASP8825
- Where
- 2 sites in Japan
- Volunteers
- 18 people
- Sponsor
- Astellas Pharma Inc
Haemodialysis
Efficacy and Local Tolerability of Topically Applied Heparin on the Suitability of Newly Constructed Primary Arteriovenous Fistulas in Patients Planned for Haemodialysis
The primary objective of this study is to evaluate the effect of topically applied heparin in comparison to placebo on suitability of newly constructed primary arteriovenous fistulas in patients planned for haemodialysis at 7th…
- Trial name
- NCT01382888
- Testing
- Heparin 2,400 IU /ml Cutaneous Spray
- Where
- 3 sites in Austria
- Volunteers
- 30 people
- Sponsor
- Cyathus Exquirere Pharmaforschungsgmbh