Clinical trials: Haemodialysis Patients
Hemodialysis Complication
Alpha Lipoic Acid Against Cardiovascular Events in Patients With Haemodialysis
Evaluate the association between possible benefit effects of oral administration of alpha lipoic acid by patients with hemodialysis and the possible reduction in cardiovascular events (CVEs); using Advanced glycation end products…
- Trial name
- NCT03912727
- Testing
- Alpha-Lipoic acid plus renal replacement therapy, renal replacement therapy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Rehab Werida
Hemodialysis
Effect of Whole Body Vibration on Walking Performance in Elderly Hemodialysis Patients
The purpose of this study is to evaluate the efficacy of whole body vibration for 12 weeks on walking performance in elderly hemodialysis patients.
- Trial name
- NCT04774731
- Testing
- Whole Body Vibration
- Where
- Japan
- Volunteers
- 98 people
- Sponsor
- Osaka University
Heart Failure, Iron-deficiency
Cardiac Biomarkers and Iron Status in Hemodialysis Patients
Background: Peripheral arterial disease (PAD) a condition characterized by atherosclerotic occlusive disease of the lower extremities is commonly observed in patients with chronic kidney disease (CKD) patients, particularly those…
- Trial name
- NCT05256004
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Chronic Kidney Diseases, Hemodialysis Complication
Efficacy and Safety of Cholestyramine in the Management of Hyperphosphatemia in Adult Hemodialysis Patients
After the end of trial, we will examine if cholestyramine has a significant efficacy on reducing serum phosphate level in adult hemodialysis patients.
- Conditions
- Chronic Kidney Diseases, Hemodialysis Complication, Hyperphosphatemia
- Trial name
- NCT05577507
- Testing
- Cholestyramine Resin 4000 MG [Questran], Calcium Carbonate 500 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Anemia of Chronic Disease
A Phase 2A Trial of FMX-8 Treatment for Anemia in Patients With ESRD on Hemodialysis HD
The trial is an uncontrolled, open-label, parallel group clinical trial. Approximately 10 subjects per dose group in 3 groups will be treated twice weekly for a total of 9 doses, followed by a 4-week observation period.
- Trial name
- NCT01873534
- Testing
- FMX-8
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- FerruMax Pharmaceuticals, Inc.
End Stage Renal Disease, Pruritus
Evaluating the Effect of Senna in Uremic Pruritus
Uremic pruritus remains one of the most frustrating and potentially disabling symptoms in patients with end stage renal disease. It affect up to 90 percent of patients with end stage renal disease.
- Trial name
- NCT02008864
- Testing
- Senna
- Volunteers
- 60 people
- Sponsor
- Shiraz University of Medical Sciences
Hypertension, Hemodialysis Patients
Dialysate Sodium Individualization in Hemodialysis
Salt and water excess is an essential mechanism of hypertension. This is particularly relevant to patients with end stage kidney disease (ESKD) on dialysis.
- Trial name
- NCT00259714
- Testing
- dialysate sodium individualization, standard dialysate sodium
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Yale University
Uremic Pruritus, Chronic Kidney Disease-associated Pruritus
Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysis
Several studies investigated the effectiveness of Gabapentin in Uremic Pruritus (UP). No previous studies investigated the use of fexofenadine in UP.
- Conditions
- Uremic Pruritus, Chronic Kidney Disease-associated Pruritus, Hemodialysis, End-stage Renal Disease
- Trial name
- NCT06466421
- Testing
- Fexofenadine, Gabapentin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
End-Stage Renal Disease Requiring Haemodialysis, Bladder Dysfunction
IMPACT OF DIALYSIS DURATION AND DIURESIS ON BLADDER CAPACITY AND COMPLIANCE IN END STAGE RENAL DISEASE PATIENTS AWAITING RENAL TRANSPLANT
Patients with end-stage renal disease (ESRD) who are on dialysis for a long time may experience bladder problems as their urine output decreases and normal bladder filling is lacking.
- Trial name
- ESRD (NCT07570771)
- Testing
- Observational Assessment
- Where
- Pakistan
- Volunteers
- 87 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Kidney Failure, Chronic
Effect of Exercise on Endothelial Function and Vascular Compliance in Chronic Kidney Disease
The study hypothesis is that 6 weeks of repetitive handgrip exercise will improve endothelial function and venous compliance in pre-dialysis patients with an estimated glomerular filtration rate of less than or equal to 20…
- Trial name
- NCT01068314
- Testing
- Repetitive arm exercise
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Iowa
Hemodialysis
Effect of Lowering the Dialysate Sodium on Blood Pressure in Hemodialysis Patients
Patients currently receiving hemodialysis will be randomized to receive 1 of 3 dialysate sodium prescriptions. The effects on blood pressure, interdialytic weight gain, thirst, and intradialytic symptoms will be assessed.
- Trial name
- NCT00724633
- Testing
- Lowering the dialysate sodium
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
End Stage Renal Disease, Inflammation
Inflammation and Nutritional Parameters in Hemodialysis Patients Using Reprocessed Dialyzers
The study is a prospective cohort trial utilizing sequential laboratory results from excess serum obtained from hemodialysis patients (acting as their own controls).
- Trial name
- NCT00440908
- Where
- 2 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Fresenius Medical Care North America
End Stage Kidney Disease
The Effect of Intradialytic Exercise on the Functional Capacity of Hemodialysis Patients
The purpose of this study is to explore the impact of an intradialytic exercise program on functional capacity, aerobic capacity, strength, quality of life, depression, hospitalizations and intradialytic episodes of hypotension.
- Trial name
- NCT01877863
- Testing
- exercise
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Chronic Kidney Disease
Optimal Titration Regimen for SBR759 in Lowering Serum Phosphate Levels in Asian Chronic Kidney Disease Patients on Hemodialysis
This study will determine the titration regimen for SBR759 compared to sevelamer HCl in lowering serum phosphate levels in Asian Chronic Kidney Disease patients on hemodialysis
- Trial name
- SBR759 (NCT00704678)
- Testing
- SBR759, Sevelamer HCl
- Where
- 15 sites in Japan, Taiwan
- Volunteers
- 203 people
- Sponsor
- Novartis Pharmaceuticals
Sudden Cardiac Death, Sudden Cardiac Arrest
Wearable Cardioverter Defibrillator in Hemodialysis Patients (WED-HED) Study
A multi-center, prospective, randomized controlled clinical trial with 1:1 assignment of treatment and control. This study will evaluate the impact of wearable cardioverter defibrillator use on sudden cardiac death in incident…
- Trial name
- WED-HED (NCT02481206)
- Testing
- Wearable Cardioverter Defibrillator
- Where
- 31 sites in United States
- Volunteers
- 66 people
- Sponsor
- Zoll Medical Corporation
Hemodialysis Complication, Heart Failure
A Study of Real-world Events of Vericiguat in Patients With Chronic Kidney Disease and Heart Failure
Chronic Kidney Disease often requires dialysis and other treatments to sustain life, and patients frequently suffer from heart failure, which exacerbates the disease burden.
- Trial name
- ESVGR-HF (NCT07047547)
- Testing
- Vericiguat
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Guangdong Provincial People's Hospital
End-stage Renal Disease (ESRD)
A Study of Safety, PK, & PD of ISIS 416858 Administered Subcutaneously to Patients With End-Stage Renal Disease on Hemodialysis
Evaluation of safety, tolerability, PK and PD of ISIS 416858 in patients with end-stage renal disease (ESRD) receiving chronic hemodialysis.
- Trial name
- NCT02553889
- Testing
- ISIS 416858
- Where
- 8 sites in Canada
- Volunteers
- 49 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Chronic Kidney Disease
Dialysis Clinical Outcomes Revisited (DCOR) Trial
This is a randomized, open-label, parallel-design study to be conducted at 75 centers within the United States. The study will be described to hemodialysis patients.
- Trial name
- NCT00324571
- Testing
- Sevelamer hydrochloride, Calcium-based phosphate binder
- Where
- 73 sites in United States, Puerto Rico
- Volunteers
- 2,000 people
- Sponsor
- Genzyme, a Sanofi Company
Dialysis Membranes and Hemodynamic Tolerance
Dialysis Membranes and Hemodynamic Tolerance
Background: High- and low-flux dialysis membranes made of different materials may correlate with various hemodynamic tolerance profiles.
- Trial name
- NCT01898234
- Testing
- Revaclear, Helixone high flux, Xevonta
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Ospedale Regionale di Locarno
Hemodialysis
Patient-Centered Physical Activity Program for Hemodialysis Patients
Individuals undergoing HD generally have very low physical activity levels, which consequently contributes to elevated levels of perceptions of fatigue, poor physical function, and a decline in overall quality of life, all of…
- Trial name
- NCT07080593
- Testing
- Novel Physical Activity Program, Standard of Care Physical Activity Program
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Illinois at Urbana-Champaign