Clinical trials: Haemorrhoid, open to volunteers
Hemorrhoids Third Degree, Internal Hemorrhoids
HELO Trial: Energy-Based Therapies vs. Conventional Hemorrhoidectomy for Grade III Hemorrhoids
This prospective, multicenter study compares the efficacy and functional outcomes of three surgical treatments for symptomatic Goligher Grade III internal hemorrhoids: Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy…
- Conditions
- Hemorrhoids Third Degree, Internal Hemorrhoids, Mixed Hemorrhoids
- Trial name
- HELO (NCT07333040)
- Testing
- Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy (HET), Ferguson Hemorrhoidectomy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Hemorrhoids
Ultrasound-guided Sacral Erector Spinae Plane Block as a Sole Anesthetic Technique Versus Saddle Block in Hemorrhoidectomy
Study interventions: The patients will be randomized into two equal groups, Group A and Group B. Group A: Patients will receive an Ultrasound guided sacral erector spinae plane block (SESPB) Group B: Patients will receive Saddle…
- Trial name
- NCT06969274
- Testing
- Ultrasound guided sacral erector spinae plane block (SESPB), Saddle block.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hemorrhoids, Postoperative Pain
Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy
The goal of this clinical trial is to evaluate whether oral nifedipine reduces postoperative pain and improves wound healing after hemorrhoidectomy in adult patients aged 18-65 years undergoing elective surgery for grade III or…
- Conditions
- Hemorrhoids, Postoperative Pain, Wound Healing, Analgesia
- Trial name
- NIFEDIPINE-HD (NCT07659665)
- Testing
- Nifedipine 20 Mg
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Hemorrhoid
ORal Aminaphtone and Combined LidocainE
This observational study, called ORACLE (ORal Aminaphtone and Combined LidocainE), is being conducted at Treviso Regional Hospital (Italy) to evaluate the effectiveness of a first-line treatment for patients with internal…
- Trial name
- ORACLE (NCT07026513)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Treviso Regional Hospital
Hemorrhoids
Ligasure Versus Conventional Diathermy in Hemorrhoidectomy
comparison study in the treatment of hemorrhoid between ligasure device and the conventional diathermy
- Trial name
- NCT07878546
- Testing
- ligasure
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hemorrhoids, Postoperative Pain
Botulinum Toxin A Before Hemorrhoidectomy to Prevent Postoperative Pain
Hemorrhoidectomy is an effective surgical treatment for advanced hemorrhoidal disease but is often associated with significant postoperative pain, which may delay recovery.
- Trial name
- BoTo-HEM (NCT07399860)
- Testing
- Botulinum toxin type A, Saline (0.9% NaCl)
- Where
- Russia
- Volunteers
- 292 people
- Sponsor
- Lomonosov Moscow State University Medical Research and Educational Center
Bleeding Hemorrhoids, Rectal Evacuation Disorders
Rectal Evacuation Disorders and Straining-associated Symptoms in Bleeding Hemorrhoids
This study aims to understand the mechanisms of straining on anorectal testing, to better help people receive more effective treatment advice.
- Trial name
- NCT07161765
- Testing
- Anorectal manometry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Colorectal Cancer, Gastric Cancer
Samples Procurement for Colorectal Cancer, Gastric Cancer, and Non-malignant Disease
The purposes of this study are to collect and store samples including blood, normal and tumor tissue from patients with colorectal cancer or gastric cancer, to collect and store samples including blood and/or normal…
- Conditions
- Colorectal Cancer, Gastric Cancer, Inflammatory Bowel Diseases, Gastric Ulcer
- Trial name
- NCT03972956
- Testing
- No intervention will be given to patients.
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Renmin Hospital of Wuhan University
Internal Hemorrhoids, HAE
Hemorrhoidal Artery Embolization: Longitudinal Impact On Symptoms (HELIOS)
Hemorrhoidal artery embolization (HAE) is a novel treatment for symptomatic internal hemorrhoids. HAE involves the deliberate blockage (embolization) of enlarged rectal or hemorrhoidal arteries leading to reduction of abnormal…
- Trial name
- HELIOS (NCT07179601)
- Testing
- Hemorrhoidal artery embolization
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Hemorrhoidal Disease, Internal Hemorrhoids
Clinical Outcomes After Laser Hemorrhoidoplasty
This single-center prospective observational study aims to evaluate clinical outcomes, postoperative pain scores, complications, and patient satisfaction in adults undergoing laser hemorrhoidoplasty for symptomatic internal…
- Trial name
- LHP (NCT07520734)
- Testing
- Laser Hemorrhoidoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Haemorrhoid, Haemorrhoidal Bleeding
Hemorrhoid Suture Mucopexy Combined With Laser Hemorrhoidoplasty
This prospective cohort study evaluates whether combining "suture mucopexy" (a simple stitch-based lift of prolapsed tissue) with Laser Hemorrhoidoplasty (LHP) can effectively relieve pain, bleeding and prolapse in adults with…
- Conditions
- Haemorrhoid, Haemorrhoidal Bleeding, Anorectal Surgeries, Anorectal Diseases
- Trial name
- HeMuLa (NCT07404774)
- Testing
- Laser Haemorrhoidoplasty and Suture Mucopexy
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Hemorrhoid, Hemorrhoid Prolapse
Data-driven Clustering in Hemorrhoid Surgery: Retrospective Monocentric Study for the Identification of Clinical Phenotypes
This retrospective, single-center observational study will use routinely collected perioperative data from adults undergoing surgery for symptomatic hemorrhoidal disease to identify data-driven clinical phenotypes.
- Trial name
- PROCTO-CLUSTER (NCT07427927)
- Testing
- Any surgical procedure for hemorrhoidal disease
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Policlinico S. Donato
Morbid Obesity, Anorectal Diseases
GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity
Prospective observational cohort study evaluating the early proctologic effects of GLP-1 receptor agonist therapy in morbidly obese patients.
- Conditions
- Morbid Obesity, Anorectal Diseases, Drug-Related Side Effects and Adverse Reactions, Constipation
- Trial name
- GLP-PROCT (NCT07668765)
- Testing
- GLP-1 receptor agonist therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gazi University
Hemorrhoid
SHAPE Versus Milligan-Morgan Hemorrhoidectomy for Hemorrhoidal Disease
This study will be conducted at the General Surgery Department, Kasr Al-Ainy Teaching Hospital, Cairo University, on patients presenting with third- and fourth-degree hemorrhoids.
- Trial name
- NCT07598630
- Testing
- Skin Sparing Hemorrhoidectomy and PExy (SHAPE), Milligan-Morgan Hemorrhoidectomy
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Hemorrhoidal Bleeding, Hemorrhoids, Internal
Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS
The purpose of this clinical trial is to compare two standard of care non-surgical treatments for hemorrhoidal bleeding: hemorrhoidal artery embolization (HAE) versus rubber band ligation (RBL).
- Conditions
- Hemorrhoidal Bleeding, Hemorrhoids, Internal, HAE, RBL
- Trial name
- STRATOS (NCT07559630)
- Testing
- Hemorrhoidal Artery Embolization, Rubber Band Ligation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Jessica K. Stewart, MD
Hemorrhoid, Hemorrhoid Bleeding
Trial of Latex vs Non-latex Hemorrhoid Banding
This study will involve the recruitment of adult patients with hemorrhoids for whom rubber band ligation is the recommended treatment. Patients will be randomized to receive banding with a latex band or non-latex band.
- Trial name
- NO-Tex (NCT06625138)
- Testing
- Latex Band, Non-Latex Band
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Huntington Memorial Hospital
Minimal Invasive Surgery, Hemorrhoidectomy
Reproducibility of a Minimally Invasive Ferguson-type Hemorrhoidectomy for Grade III Hemorrhoids
Hemorrhoids are vascular-elastic structures of the anal canal that contribute to continence. Their enlargement and descent lead to symptoms such as rectal bleeding and the sensation of anal swelling, known as hemorrhoidal…
- Trial name
- NCT07695649
- Testing
- Minimal invasive closed hemorrhoidectomy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Son Llatzer
Incarcerated Mixed Hemorrhoids
Application of Dynamic Pain Assessment and Management System in Perioperative Period of Patients With Incarcerated Mixed Hemorrhoids
This study aims to investigate whether the dynamic pain assessment and management system can alleviate postoperative pain in patients with incarcerated mixed hemorrhoids and reduce the incidence of complications.
- Trial name
- NCT07183345
- Testing
- Dynamic Pain Assessment and Management System, Routine drug analgesia
- Where
- China
- Volunteers
- 64 people
- Sponsor
- The Affiliated Hospital of Putian University
Haemorrhoid
Traditional Ferguson Hemorrhoidectomy vs Stapled Hemorrhoidopexy
This study aimed to compare the short- and long-term outcomes of stapled hemorrhoidopexy (the procedure for prolapsed hemorrhoids, PPH) with anoplasty versus traditional Ferguson method for the treatment of patients with grade…
- Trial name
- NCT05959577
- Testing
- Stapled hemorrhoidopexy with anoplasty, Ferguson hemorrhoidectomy
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Hemorrhoids
Trans-radial Superior Rectal Artery Embolisation for Haemorrhoids
Endovascular embolisation is already a common procedure for bleeding haemorrhoids in the acute setting, where surgical options are not possible or have been exhausted.
- Trial name
- NCT06175325
- Testing
- Trans-radial embolisation of haemorrhoids
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University Hospitals of North Midlands NHS Trust