Clinical trials: Hair Diseases
Alopecia Areata
Study of DAXDILIMAB for the Treatment of Moderate-to-Severe Alopecia Areata
The purpose of this study is to assess the preliminary efficacy, safety, tolerability, PK, and PD of Daxdilimab in participants with moderate to severe AA, with ≥50% and ≤95% total scalp hair loss as defined by the SALT score at…
- Trial name
- NCT05368103
- Testing
- Daxdilimab
- Where
- 13 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- Amgen
Alopecia Areata, Alopecia Totalis
Alopecia Areata Registry
Alopecia areata is the loss of hair in patches that can proceed to loss of all hair (alopecia totalis or universalis). The purpose of the registry is to collect patient information and blood samples from people with alopecia…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Autoimmune Hair Loss
- Trial name
- NAAR (NCT00069589)
- Where
- 5 sites in United States
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Tooth Discoloration, Tooth Sensitivity
Clinical Efficacy of Novel Titanium Oxide Nanoparticle Enriched Bleaching Gel
The goal of this clinical trial is to learn the effect of Nano-fortified Bleaching on whitening and sensitivity of teeth.The main questions it aims to answer are: Does Nano-fortified Bleaching gel is more effective in enhancing…
- Trial name
- NCT06904118
- Testing
- Nano-reinforced Novel Hydrogen peroxide gel, Conventional Hydrogen peroxide gel without nanoparicles
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Hirsutism, Hair Diseases
Suppression of Upper Lip Hair Growth Using Novel Hemp Extract
A clinical case series will be conducted measuring upper lip hair suppression for cosmetic effects in a group of 25 adult women with hirsutism of the upper lip.
- Trial name
- NCT06003062
- Testing
- Narcissus Tazetta Bulb Extract and Novel Hemp Extract
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical Life Care Planners, LLC
Alopecia Areata
An Open-Label Single-Arm Clinical Trial to Evaluate The Efficacy of Abatacept in Moderate to Severe Patch Type Alopecia Areata
Alopecia areata (AA) is a common disease of the immune system, known as an "autoimmune" disease. In this disease, the immune system mistakenly destroys the hair follicle, causing hair to fall out.
- Trial name
- NCT02018042
- Testing
- Abatacept
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Columbia University
Hair Thinning
Efficacy and Tolerability of a Scalp Serum
The goal of this clinical trial is to evaluate the efficacy and tolerability of a scalp serum on 60 healthy females aged 25 to 65 years with Fitzpatrick skin phototypes I-VI and with mild to moderate thinning hair.
- Trial name
- NCT07500623
- Testing
- Scalp Serum
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Revision Skincare
Hair Thinning
Pilot Study to Evaluate the Efficacy and Safety of Xvie Delivered Into the Scalp by Microneedling in Women With Self-perceived Thinning Hair
The goal of this study is to determine how safe and effective it is to improve hair growth using XVIE solution applied on the scalp of women with self-perceived thinning hair. The main aims of this trial are: 1.
- Trial name
- NCT07221773
- Testing
- XVIE
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Restore Biologics Holdings, Inc. dba Xtressé
Premature Ovarian Insufficiency, POI
Autologous Hair Follicle-Derived Secretome and Platelet-Rich Plasma for Premature Ovarian Insufficiency
This single-arm, open-label pilot study aims to evaluate changes in ovarian function following administration of autologous hair follicle-derived mesenchymal stem cell secretome combined with autologous platelet-rich plasma (PRP)…
- Conditions
- Premature Ovarian Insufficiency, POI, Primary Ovarian Insufficiency (Poi), Premature Ovarian Failure (POF)
- Trial name
- NCT07916740
- Testing
- Autologous Hair Follicle-Derived Secretome Combined With Platelet-Rich Plasma
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Trio Fertility
Lung Cancer
Clearance of NNAL and Cotinine From Second-hand Smoke in Hair and Urine
This study will investigate how long it takes for NNAL and cotinine, markers of second hand smoke, to clear the human body.
- Trial name
- NNAL (NCT00863824)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Trichotillomania
Feasibility Study for Treating Trichotillomania With Wearable Device and App System
Trichotillomania is characterized by recurrent hair pulling resulting in hair loss causing significant distress and impairment which persists despite repeated attempts to stop.
- Trial name
- NCT04241120
- Testing
- Device and app system designed for participant to self-administer Habit Reversal Training, Reminder bracelet control condition
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HabitAware Inc.
Acne, Acne Vulgaris
A Pilot Study to Explore the Role of Gut Flora in Acne
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Acne, Acne Vulgaris, Acne Keloidalis, Acne Keloid
- Trial name
- NCT04214483
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Alopecia, Canities
6-Month Trial of Chinese Herbal Treatments for Hair Loss and Gray Hair
This will be a 6-month randomized, double-blind, placebo-controlled trial. A total of 152 participants with hair loss, including some with gray hair, will be enrolled and randomly assigned to four groups.
- Trial name
- NCT06998680
- Testing
- VitaGreen Capsule A+VitaGreen Tonic, VitaGreen Capsule B+VitaGreen Tonic
- Where
- China
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Vita Green Pharmaceutical (H.K.) Ltd.
Androgenetic Alopecia
A Phase 2a Trial of FOL-005 Topical Formulations to Investigate Hair Growth Potential and Safety in Healthy Male Volunteers
This exploratory phase IIa, double blind, randomized, vehicle controlled, multicenter dose-finding trial will evaluate the safety, tolerability, and efficacy of FOL-005 topical formulation (at 0.1%, 0.5% and 1.5% strength)…
- Trial name
- NCT04774874
- Testing
- Topical formulation
- Where
- Germany
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Follicum AB
Alopecia Areata
A First in Human Single and Multiple Ascending Dose and Open Label Food Effect Study of OR-101 in Healthy Subjects
This first in human phase 1 study to Study will evaluate safety, tolerability, and pharmacokinetics of Single Ascending dose (SAD), Food effect (FE) and Multiple ascending dose (MAD) of OR-101 Administered Orally in healthy…
- Trial name
- NCT06045624
- Testing
- OR-101 (Single ascending dose), OR-101 (Food effect), OR-101 (Multiple ascending dose)
- Where
- Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ornovi, Inc.
Androgenetic Alopecia
Comparing Different Platelet Rich Plasma (PRP) Treatment Regimens for Management of Androgenic Alopecia
The injection of autologous platelet rich plasma (PRP) is a relatively novel therapy, generating interest across a wide variety of medical specialties, such as orthopedics, dentistry, ophthalmology, and dermatology.
- Trial name
- NCT02999737
- Testing
- Platelet Rich Plasma for 4 sessions, Platelet rich plasma for 2 sessions
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Skin Care and Laser Physicians of Beverly Hills
Alopecia Areata
Study to Evaluate the Efficacy and Safety of CTP-543 in Adults With Moderate to Severe Alopecia Areata (THRIVE-AA1)
This study evaluates the safety and effectiveness of an investigational study drug (called CTP-543) in adults (18 years and older) who have 50% or greater scalp hair loss.
- Trial name
- THRIVE-AA1 (NCT04518995)
- Testing
- CTP-543
- Where
- 72 sites in United States, Canada and 3 more
- Volunteers
- 706 people
- Sponsor
- Concert Pharmaceuticals
Alopecia, Androgenetic
Study of TDM-105795 Following Topical Administration in Male Subjects With Androgenetic Alopecia
Randomized, double-blind, vehicle-controlled, parallel group, multi-dose study of TDM-105795 in male subjects with androgenetic alopecia
- Trial name
- NCT05802173
- Testing
- TDM-105795, 0.0025%, TDM-105795, 0.02%, TDM-105795 topical vehicle solution
- Where
- 13 sites in United States
- Volunteers
- 71 people
- Sponsor
- Technoderma Medicines Inc.
Atopic Dermatitis, Psoriasis
Determinants of Chronic Inflammatory Skin Disease Trajectories
Although it is well known that the clinical expression and course of chronic inflammatory skin diseases are highly variable, there are insufficient epidemiological data on this, and the factors that determine the manifestation…
- Conditions
- Atopic Dermatitis, Psoriasis, Lichen Planus, Alopecia Areata
- Trial name
- NCT05928169
- Testing
- Topical and systemic drugs
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Acne Keloidalis Nuchae
Treatment of Acne Keloidalis Nuchae (Razor Bumps Behind the Neck) Using UV Light Therapy
This study is being done to evaluate the effect of targeted UV-B (a component of sunlight) on the treatment of acne keloidalis nuchae (AKN, or razor bumps on the back of the neck).
- Trial name
- NCT01328080
- Testing
- Targeted UV-B
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Johns Hopkins University
Hypertrichosis
Pilot Study of a Novel IPL for Removal of Unwanted Fine Body Hair
The purpose of this randomized, controlled, open-label pilot study is to evaluate the safety and efficacy of a novel intense pulsed light (IPL) device for removal of unwanted fine body hair.
- Trial name
- NCT01912950
- Testing
- Prowave LX IPL
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.