Clinical trials: Hair Problems
Alopecia Areata (AA), Alopecia Totalis (AT)
Tofacitnib for the Treatment of Alopecia Areata and Variants
The purpose of this study is to investigate the ability of tofacitinib citrate, a Janus kinase inhibitor, to generate hair regrowth in patients with moderate to severe alopecia areata and its variants.
- Conditions
- Alopecia Areata (AA), Alopecia Totalis (AT), Alopecia Universalis (AU)
- Trial name
- NCT02197455
- Testing
- Tofacitinib Administration
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Scalp Health, Hair Condition
Scalp Care Efficacy Evaluation for Premium Revitalizing Elixir
The study aims to evaluate the efficacy of the Premium Revitalizing Elixir on human scalp skin. A total of 60 healthy adults, aged 18 to 60 with alopecia, baldness, or self-identified with symptoms of hair thinning will be…
- Conditions
- Scalp Health, Hair Condition, Hair Loss, Alopecia
- Trial name
- NCT07271212
- Testing
- Base formula only, Base formula plus IGF-1 and FGF-7, Base formula plus Centella asiatica and ginger extracellular vesicles
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Androgenetic Alopecia
Evaluate the Clinical Effectiveness of RegenKit Platelet-rich Plasma (PRP) in Androgenetic Alopecia Treatment
Platelet rich plasma (PRP) therapy is a novel therapeutic modality that has seen broad applications for a number of medical indications including those in orthopedics, dentistry, and dermatology.
- Trial name
- NCT02591355
- Testing
- Autologous Platelet Rich Plasma, Saline solution injection
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Regen Lab SA
Alopecia Areata
Intralesional Vitamin D in Alopecia Areata
To evaluate the efficacy and safety of intralesional injection of vitamin D3 versus intralesional injection of corticosteroids in treatment of alopecia areata.
- Trial name
- NCT04660786
- Testing
- triamcinolone acetonide, vitamin D
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Alopecia Areata
Comparative Study for Treatment of Alopecia Areata Using Carboxytherapy and Intralesional Steroids
Patients with three lesions of alopecia areata are randomly recruited in this study. Each lesion is randomized in to receiving either carboxytherapy in one lesion, intralesional steroids in another lesion and combination of both…
- Trial name
- NCT04228029
- Testing
- Carboxytherapy, Intralesional Steroid Injection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kasr El Aini Hospital
Androgenic Alopecia
Hair Growth Efficacy and Safety of NGF-574H in Adult With Androgenic Alopecia
The purpose of this study is to assess whether cosmetic investigational product containing NGF-574H is safe and effective in the treatment of androgenic alopecia in asian adults.
- Trial name
- NCT03676400
- Testing
- conditioned media of umbilical cord blood-derived stem cells
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Medipost Co Ltd.
Alopecia Areata
Evaluation of the Effect of Topical Calcipotriol Versus Platelet-Rich Plasma
Alopecia areata (AA) is a common, immune-mediated non scarring alopecia and can be associated with severe psychological consequences . Alopecia Areata affects 2% of the global population.
- Trial name
- NCT05954104
- Testing
- Calcipotriol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Alopecia Areata
A Clinical Trial to Evaluate the Efficacy of Abatacept in Moderate to Severe Alopecia Areata
The purpose of this study is to determine if receiving sub-cutaneous injections of a medication called abatacept causes regrowth of hair in people with alopecia areata.
- Trial name
- NCT01917058
- Testing
- Abatacept
- Where
- United States
- Sponsor
- Columbia University
Hirsutism, Hypertrichosis
Enhanced Safety Laser Hair Removal System
The purpose of this study is to determine whether a new laser system provides better safety and efficacy in hair removal than existing lasers.
- Trial name
- NCT00441948
- Testing
- Peterio
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Scilex Ltd.
Alopecia, Androgenetic, Baldness
A Safety and Efficacy Study of PDFE-2304 Topical Solution for the Treatment of Androgenic Alopecia.
This study will evaluate the safety and efficacy of PDFE-2304 compared with Minoxidil 5% in men with androgenic alopecia (AGA).
- Conditions
- Alopecia, Androgenetic, Baldness, Androgenetic Alopecia (AGA)
- Trial name
- NEOPILI-2A (NCT07011485)
- Testing
- Minoxidil 5% Topical Solution, PDFE-2304 Topical Solution
- Where
- India
- Volunteers
- 15 people
- Sponsor
- PDFE Pharma Innovations FZCO
Androgenetic Alopecia
Plasma Rich in Growth Factors (PRGF-Endoret)in the Treatment of Androgenetic Alopecia
Androgenetic alopecia (AGA) or common baldness is the most common cause of hair loss in both men and women and is caused by the action of androgens in genetically predisposed individuals.
- Trial name
- NCT01885676
- Testing
- PRGF-Endoret, Saline Solution
- Where
- 2 sites in Spain
- Sponsor
- Biotechnology Institute IMASD
Alopecia Areata
TREg Activation in the Treatment of the PELADE (Alopecia Areata)
In a prospective pilot study the investigators showed that low doses of IL2 could be beneficial for severe AA inducing a long lasting regrowth in 4 out of the 5 patients treated.
- Trial name
- TreatPelade (NCT02557074)
- Testing
- IL2
- Where
- 6 sites in France
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Menkes Syndrome
Recombinant Adeno-associated Virus Administration for Patients With Menkes Syndrome
It is a single-center, open, single-arm, non-randomized investigator-initiated trial evaluating the efficacy and safety of recombinant adeno-associated virus administration for patients with Menkes syndrome.
- Trial name
- NCT05507996
- Testing
- Recombinant adeno-associated virus administration
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Kunming Hope of Health Hospital
Hair Loss
Natural History and Pathogenesis of Alopecia in Children and Adults
Background: Alopecia is the loss of hair or lack of hair growth. It is often related to an immune disorder that disrupts the growth of hair. Hair loss can affect a person s physical and mental health.
- Trial name
- NCT05502796
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Acne, Alopecia
To Evaluate the Safety, Tolerability and PK of GT20029 Gel and Solution in Healthy Subjects
The study is a randomized, double-blind, vehicle-controlled, parallel group, phase 1 study to evaluate the Safety, Tolerability and PK of GT20029 in healthy subjects
- Trial name
- NCT06468579
- Testing
- GT20029
- Where
- China
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Suzhou Kintor Pharmaceutical Inc,
Androgenetic Alopecia (AGA), Chronic Telogen Effluvium
Evaluation of the Dietary Supplement Efficacy Against Hair Loss in Subjects Suffering From Hair Loss
The goal of this study was to learn if dietary supplement in capsules and drinkable works to help hair loss in volunteers with chronic telogen effluvium and androgenetic alopecia and learn about its safety.
- Trial name
- NCT07358403
- Testing
- Dietary supplement capsule use for hair loss, Dietary supplement drinklable use for hair loss
- Where
- Italy
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Lacer S.A.
Androgenetic Alopecia, Exosomes
Exosome Treatment in Androgenetic Alopecia
This study aims to elucidate the effect of "foreskin-derived mesenchymal stromal cells derived exosome" injection into the scalp on hair density in patients with androgenetic alopecia and the contribution of this treatment on…
- Trial name
- NCT06539273
- Testing
- Exosome Complex, RNA
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yeditepe University Hospital
Alopecia Areata
Alefacept in Patients With Severe Scalp Alopecia Areata
The purpose of this study is to examine prospectively the safety and efficacy of alefacept in the treatment of subjects with severe alopecia areata of the scalp.
- Trial name
- NCT00167102
- Testing
- Alefacept
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Alopecia Areata, Alopecia Totalis
Clinical Trial to Evaluate the Efficacy of Fecal Microbiota Transplantation in Patients With Alopecia Areata
The purpose of this study is to examine fecal transfer as a potential treatment for Alopecia Areata (AA). This trial will attempt to discover if fecal transfer can treat immune-related hair loss.
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis
- Trial name
- NCT04238091
- Testing
- Fecal material transfer therapy, 4mm Punch Biopsy of Scalp, Blood draw
- Sponsor
- Lindsey Bordone
Alopecia Areata, Alopecia Totalis
Phase 2 Trial of BNZ-1 in Patients With Moderate to Severe Alopecia Areata
This study is a randomized, double-blind, placebo-controlled, multi-center, dose-ranging study to characterize the efficacy and safety of BNZ-1 administered by slow IV push weekly for 3 months to adults diagnosed with moderate to…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis
- Trial name
- NCT03532958
- Testing
- BNZ-1, Normal saline
- Sponsor
- Equillium