Clinical trials: Hallucinations
Psychotic Disorders, Mood Disorders
Transcranial Direct Current Stimulation as Treatment for Auditory Hallucinations
The present study aims to examine the efficacy of transcranial direct current stimulation on the severity of auditory hallucinations.
- Conditions
- Psychotic Disorders, Mood Disorders, Personality Disorders, Stress Disorders, Post-Traumatic
- Trial name
- tDCS (NCT01977521)
- Testing
- Eldith DC Stimulator stimulation
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Iris Sommer
Auditory Hallucination, Schizophrenia
Transcranial Direct-current Stimulation (tDCS) in Treatment Refractory Auditory Hallucinations
This is a 4 week therapeutic pilot study with a 4 week follow-up period involving inpatients with treatment resistant DSM-IV schizophrenia or schizoaffective disorder diagnosis.
- Trial name
- tDCS (NCT03485131)
- Testing
- Transcranial direct-current stimulation (tDCS)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Manhattan Psychiatric Center
Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis, Hallucinations and Delusions Associated With Parkinson Disease Psychosis
A Phase 1, MAD Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LY03017
This is a phase 1，randomized, double-blind, placebo-controlled, MAD study to evaluate the safety, tolerability and pharmacokinetics of oral LPM526000133 Fumarate Capsules (LY03017) in healthy adult subjects
- Conditions
- Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis, Hallucinations and Delusions Associated With Parkinson Disease Psychosis, Negative Symptoms of Schizophrenia
- Trial name
- NCT06980207
- Testing
- LY03017
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Narcolepsy Type 1, Hypnagogic Hallucinations
Imagery Control Therapy and Lucid Dreaming for REM-Related Symptoms in Narcolepsy
This randomized controlled trial evaluated the efficacy of a cognitive behavioral intervention based on lucid dreaming training and imagery control therapy for reducing REM-related symptoms in patients with narcolepsy type 1.
- Conditions
- Narcolepsy Type 1, Hypnagogic Hallucinations, Sleep Paralysis, REM Sleep Intrusion Symptoms
- Trial name
- ICLDR-NAR Tria (NCT07609537)
- Testing
- Cognitive Behavioral Therapy for Narcolepsy (CBT-NAR) With Lucid Dreaming and Imagery Control Therapy, Sleep Hygiene Education and Structured Clinical Follow-up
- Where
- Colombia
- Volunteers
- 98 people
- Sponsor
- Institute of Behavioral Sleep Medicine, Colombia
Wound Care, Pain Intensity
Pain Medicine for Wound Care Procedures
This is a randomized double-blind study to determine if the administration of a small-dose of ketamine (an anesthetic)added to morphine (an opioid) contributes to reducing pain intensity during open wound care procedure (WCP)in…
- Conditions
- Wound Care, Pain Intensity, Hyperalgesia, Nausea
- Trial name
- NCT00701909
- Testing
- Morphine plus Ketamine
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Schizophrenia, Transcranial Magnetic Stimulation
Evaluation of the Efficacy of Transcranial Magnetic Stimulation on Resistant Auditory Hallucinations in Schizophrenia
This open naturalistic study aims to evaluate the efficacy of rTMS in routine practice on auditory resistant hallucinations (AHR) of patients with schizophrenia.
- Conditions
- Schizophrenia, Transcranial Magnetic Stimulation, Hallucinations, Verbal Auditory
- Trial name
- HRRENAT (NCT06599372)
- Testing
- The rTMS method, The cTBS method
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Dominique JANUEL
Auditory Hallucination
SMA Targeted Magnetic Stimulation Against Auditory Verbal Hallucinations
Auditory verbal hallucinations (AVH) are prevalent among patients with psychiatric disorders. Not only being highly stressful and functionally impairing, AVH often persist despite treatment.
- Trial name
- SMA-AVH (NCT04651621)
- Testing
- continuous theta burst stimulation over the SMA
- Where
- Sweden
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Schizophrenia, Psychotic Disorders
Theta Burst Transcranial Magnetic Stimulation as Treatment for Auditory Verbal Hallucinations
Auditory verbal hallucinations (AVH) are a characterising symptom of schizophrenia. In the majority of patients, these AVH respond well to antipsychotic medication.
- Trial name
- NCT01512290
- Testing
- Theta Burst Transcranial Magnetic Stimulation
- Where
- Netherlands
- Volunteers
- 71 people
- Sponsor
- UMC Utrecht
Schizophrenia With Auditory Hallucinations
Frequency- and Intensity-Dependent After-Effects of High-Definition Transcranial Alternating Current Stimulation on Resting-State Electroencephalography
This study aims to investigate the after-effects of high-definition transcranial alternating current stimulation (HD-tACS) with varying parameters on resting-state brain activity in patients with schizophrenia experiencing…
- Trial name
- NCT07798804
- Testing
- high-definition transcranial alternating current stimulation(HD-tACS)
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Parkinson's Disease, Hallucinations, Visual
Apomorphine in Parkinson's Disease Patients With Visual Hallucinations
This randomised, double-blind, placebo-controlled trial will evaluate the efficacy of continuous apomorphine infusion compared to placebo in PD patients with visual hallucinations, inadequately controlled with clozapine and…
- Trial name
- NCT02702076
- Testing
- Apomorphine
- Where
- Netherlands
- Volunteers
- 35 people
- Sponsor
- University Medical Center Groningen
Alzheimer Disease, Cataract
Life From Vision in Alzheimer Disease
The VIVA study is focused on Alzheimer's disease patients with a low vision due to a bilateral cataract. The aim is to study cataract surgery results on patients' autonomy, behaviour, and mood.
- Trial name
- VIVA (NCT00838942)
- Testing
- Questionaries
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Schizophrenia
Transcranial Magnetic Stimulation for the Treatment of Auditory Hallucinations in Schizophrenia
Repetitive transcranial magnetic stimulation (rTMS) is a new noninvasive therapy that uses magnetic energy applied to the scalp to modulate activity in the underlying regions of the brain.
- Trial name
- NCT01595503
- Testing
- rTMS with fMRI-based targeting, rTMS with landmark-based targeting
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Michigan
Parkinson Disease
Phenomenological and Psychopathological Factors Associated to Hallucinations in Parkinson's Disease
This study aims to describe hallucinations prevalence in a sample of patients affected by Parkinson's disease and consulting in an outpatient facility. An unique one hour interview will be offered to volunteers patients.
- Trial name
- HALLUPARK (NCT03105401)
- Testing
- Assessment of hallucinations in Parkinson's disease
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Hospices Civils de Lyon
Charles Bonnet Syndrome
Charles Bonnet Syndrome in Low Vision Patients
Among patients with chronic and degenerative ocular diseases that cause visual limitations, the presence of Charles Bonnet Syndrome (CBS) may be detected as a comorbidity.
- Trial name
- CBS (NCT07563101)
- Where
- Italy
- Volunteers
- 640 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Schizophrenia, Hallucinations
Transcranial Magnetic Stimulation for "Voices"
This study will determine the efficacy of MRI-guided transcranial magnetic stimulation (TMS)in reducing "voices" and other symptoms experienced by people with schizophrenia and schizoaffective disorder.
- Trial name
- NCT00308997
- Testing
- 1-hertz Repetitive Transcranial Magnetic Stimulation, Active 1-Hertz Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Yale University
Psychotic Disorders, Veterans
Impact of VVV Group for Veterans With SMI
Veterans with Serious Mental Illness (SMI) struggle with social integration - participation in work, housing, and citizenship - due to symptoms, stigma, and psychosocial challenges.
- Trial name
- VVV (NCT05562674)
- Testing
- Veteran Voices and Visions
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Schizophrenia, Auditory Hallucinations
LIFU Effects & Outcomes: Mechanisms Evaluating Striatal Systems Imaging (LEO MESSI)
Individuals with schizophrenia often experience persistent auditory hallucinations despite treatment with antipsychotic medications.
- Trial name
- MESSI-LEO (NCT07710989)
- Testing
- LIFU
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Auditory Hallucinations, Schizophrenia
Non-Invasive Brain Stimulation for Medication-Resistant Auditory Hallucinations in Schizophrenia Patients
The overarching goal of this project is to expand the traditional expertise in non-invasive neuromodulation at the University of Minnesota towards developing novel neuromodulation approaches using transcranial direct current…
- Trial name
- NCT02240446
- Testing
- Active tDCS
- Where
- United States
- Sponsor
- University of Minnesota
Prevalence, Psychiatrist Intervention
A Trial of Patients With a Charles Bonnet Syndrome
Charles Bonnet Syndrome (CBS) is defined by the occurence of visual hallucinations (VH) in the absence of any mental disorder. Elderly patients with reduced visual acuity due to ophthalmic diseases are most affected.
- Trial name
- CBS (NCT03148249)
- Testing
- interview
- Volunteers
- 34 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Schizophrenia
Structural and Functional Correlates of Clinical Response to rTMS Treatment in Schizophrenia Patients With Resistant Auditory Hallucinations
The potential of non-invasive Transcranial Magnetic Stimulation (TMS) as a therapeutic tool for improving schizophrenic symptoms, in particular resistant hallucinations, has been increasingly studied over the past decades.
- Trial name
- TMSCCS (NCT02755623)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France