Clinical trials: Hand Arthritis
Osteoarthritis, Hand Osteoarthritis
Balneotherapy and Peloid Therapy Impact Small Joint Diseases
This clinical trial investigates the effects of natural healing factors (mineral water and mud procedures) in combination with regular rehabilitation of patients with degenerative small joint disease.
- Conditions
- Osteoarthritis, Hand Osteoarthritis, Foot Osteoarthritis
- Trial name
- NCT06477393
- Testing
- Regular rehababilitation, Heat procedures, Healing mud application
- Where
- 2 sites in Lithuania
- Volunteers
- 130 people
- Sponsor
- Lithuanian University of Health Sciences
Osteoarthritis
Study of the Use of Laser Light to Treat Osteoarthritis of the Hand.
The purpose of this study is to determine whether low level light therapy is effective in the treatment of osteoarthritis of the hand, when the treatment is applied to the hand by an individual in his or her own home.
- Trial name
- NCT00254111
- Testing
- Ultra Probe Laser System
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- TriTech Manufacturing
Osteoarthritis, Knee
Orthosensor vs Conventional Total Knee Arthroplasty
In a randomized-controlled fashion, this investigation will evaluate the use of the Verasense technology to achieve optimal TKA balance.
- Trial name
- NCT03628378
- Testing
- Verasense
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- Columbia University
Rheumatic Arthritis
Effects of Task-Oriented Training and Mulligan Mobilization on Hand Function, Pain and Quality of Life in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic and progressive inflammatory disease that frequently affects the hand joints. Over time, this disease leads to joint deformities, pain, decreased muscle strength and severe impairment in…
- Trial name
- NCT07029113
- Testing
- Task-oriented trainig, Mulligan mobilization, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Rheumatoid Arthritis, Lymph Node Mass
Relationship Between the Activity of Rheumatoid Arthritis and Lymph Node Morphology and Lymphatics Drainage
To observe the relationship between the activity of rheumatoid arthritis and popliteal/epitrochlear lymph node morphology and the drainage of hand/foot superficial lymphatic vessels
- Conditions
- Rheumatoid Arthritis, Lymph Node Mass, Lymphatic Vessel; Dilatation
- Trial name
- NCT02876874
- Testing
- indocyanine green(ICG)
- Where
- 2 sites in China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Disorders of Synovium, Multiple Sites, Disorders of Subchondral Bone, Multiple Sites
Articular Sonography: Healthy Subjects Versus Rheumatoid Arthritis Patients
The purpose of this study is to establish the normality of sonographic synovial measures in joints more affected in rheumatoid arthritis patients and establish, in those joints, a sonographic value of synovium predictive of…
- Conditions
- Disorders of Synovium, Multiple Sites, Disorders of Subchondral Bone, Multiple Sites, Disorders of Cartilage, Hand Joints, Arthritis, Rheumatoid
- Trial name
- NCT01476865
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Rheumatoid Arthritis, Pain
Effect of Antiinflammatory Treatment Versus Hand Training on Neuropsychiatric Comorbidity in RA-patients
The purpose of this study is to investigate how RA affect the brain structures in RA-patients and if anti-inflammatory treatment that target TNF-α or JAK OR physical training of hands has positive impact on neuropsychiatric…
- Conditions
- Rheumatoid Arthritis, Pain, Fatigue, Cognitive Decline
- Trial name
- NeuMRA (NCT04378621)
- Testing
- TNF-α inhibitor OR JAK inhibitor, Hand training
- Where
- Sweden
- Volunteers
- 212 people
- Sponsor
- Vastra Gotaland Region
Osteoarthritis
Open-label Safety Extension Study of Gevokizumab in Erosive Osteoarthritis of the Hand
The purpose of this study is to evaluate the long-term safety of gevokizumab in the treatment of active inflammatory, erosive osteoarthritis of the hand.
- Trial name
- NCT02293564
- Testing
- gevokizumab
- Where
- 28 sites in United States
- Volunteers
- 312 people
- Sponsor
- XOMA (US) LLC
Diabetes Mellitus, Arthritis
Adaptive Device for Insulin Pens for Arthritic Patients
Approximately 34 subjects will be enrolled in an unblinded cross-over design. For one week, they will use the adaptive pen device and for the next week, they will use just the insulin (or other medication) pen.
- Trial name
- NCT02779816
- Testing
- Pen device
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Levenson, David I., M.D.
Bilateral Arthritis of Wrist, Tendinopathy
Vibratory Anesthesia on Pain Following Corticosteroid Injections
This research study aims to evaluate injectional pain at the site of needle insertion for corticosteroid injections (CSI) of the upper extremity depending on different modes of anesthetics.
- Conditions
- Bilateral Arthritis of Wrist, Tendinopathy, Arthropathy, Compression Neuropathy
- Trial name
- NCT07553273
- Testing
- Digivibe Device
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Osteoarthritis
An RSA and DEXA Study on Migration of Proximal Interphalangeal (PIP) Joint Prostheses of the Hand
The purpose of this study is to compare the early migration and the periprosthetic bone changes of cemented versus non-cemented interphalangeal implants using Roentgen stereophotogrammetric analysis and dual energy x-ray…
- Trial name
- NCT00175188
- Testing
- Avanta (PIP joint implant with a titanium porous coating)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Chronic Pain, Arthritis Hand
Effects of the Nottingham Augmented Reality (AR) App for Arthritis Hand Joint Pain
The aim of this run-in design, feasibility study is to assess outcomes (including opioid-use, pain intensity, emotional function, and general physical function) for an augmented reality illusion therapy in participants with…
- Conditions
- Chronic Pain, Arthritis Hand, Opioid Use
- Trial name
- NCT05634291
- Testing
- Standard of care, Nottingham AR smartphone app with active intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- VRx Medical Inc
Osteoarthritis Hand
CapFlex PIP Implant RSA
Rationale: Patients with osteoarthrtis (OA) of the proximal interphalangeal (PIP) joint are commonly treated with joint arthroplasty.
- Trial name
- Capflex RSA (NCT05484089)
- Testing
- CapFlex PIP implant
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Early Rheumatoid Arthritis
Power Doppler in Hand Joints of Early RA Patients
It is a prospective case-control study with women diagnosed early rheumatoid arthritis. Three therapeutic failures were considered: failure 1 - to the first Disease-modifying antirheumatic drugs (DMARDs) (methotrexate); failure 2…
- Trial name
- NCT04752748
- Testing
- Drug protocol
- Volunteers
- 48 people
- Sponsor
- Federal University of São Paulo
Rheumatoid Arthritis
Factors Affecting Hand Dysfunction in Patient With Rheumatoid Arthritis and Its Correlation With Quality of Life
The aims of the research are: To predict factors affecting hand dysfunction in patient with rheumatoid arthritis To study the effect of hand dysfunction on quality of life in patient with rheumatoid arthritis
- Trial name
- NCT03274570
- Volunteers
- 100 people
- Sponsor
- Assiut University
Rheumatoid Arthritis - Hand Joint, Osteoarthritis Hand
Effectiveness of an Exercise Program and Education Through a Mobile Application for the Management of Patients With Hand Osteoarthritis and Rheumatoid Arthritis
Strengthening and stretching exercise programs, and recommendations to protect the affected joint have shown to be effective both clinically and economically in conditions such as hand osteoarthritis and hand rheumatoid…
- Conditions
- Rheumatoid Arthritis - Hand Joint, Osteoarthritis Hand, Pain, Mobility Limitation
- Trial name
- NCT04263974
- Testing
- Smartphone Application, Conventional treatment
- Where
- Spain
- Volunteers
- 213 people
- Sponsor
- University of Seville
Hand Osteoarthritis
Efficacy of Shinabro in Hand Osteoarthritis
GCSB-5 ("Shinbaro capsule"), is a mixture of 6 oriental herbs that have anti-inflammatory and analgesic effects along with an excellent safety profile.
- Trial name
- NCT01910116
- Testing
- Shinbaro
- Where
- 3 sites in South Korea
- Volunteers
- 220 people
- Sponsor
- Seoul National University Hospital
Infection, Hand Injury Wrist
Vancomycin Tissue Concentrations by Bier Block or Intravenous Administration
The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (upper extremity) is more effective at preventing infection than the current standard dose…
- Conditions
- Infection, Hand Injury Wrist, Hand Injuries, Hand Injuries and Disorders
- Trial name
- NCT04673877
- Testing
- Systemic IV Vancomycin, Bier Block, Vancomycin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Knee Osteoarthritis
The Effect of "Laying on of Hands" in Older Women With Knee Osteoarthritis
Osteoarthritis (OA) is the most common form of chronic degenerative joint disease, as well as the main cause of pain and disability in older persons worldwide.
- Trial name
- NCT02917356
- Testing
- Spiritual laying on of hands (SP), Non-spiritual Laying on of Hands, Control group
- Where
- Brazil
- Volunteers
- 105 people
- Sponsor
- Federal University of Juiz de Fora
CMC Arthritis, Occupational Therapy
Trapeziectomy and Suture Suspensionplasty for Thumb Carpometacarpal Arthritis - Is In-Clinic Therapy Needed?
The study is a randomized, controlled trial to evaluate the efficacy of formal occupational therapy on outcomes following CMC arthroplasty
- Conditions
- CMC Arthritis, Occupational Therapy, Hand Arthritis
- Trial name
- NCT06820528
- Testing
- Occupational Therapy, Home Exercise Program
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Julie Nuelle