Clinical trials: Hard of Hearing
Retinitis Pigmentosa, Usher Syndrome Type 2
Retinal Imaging in CNTF -Releasing Encapsulated Cell Implant Treated Patients for Early-stage Retinitis Pigmentosa
This clinical trial is a single-site, 30 patient study for participants who have early stage retinitis pigmentosa, or Usher syndrome (type 2 or 3). Funding Source - FDA OOPD and Foundation Fighting Blindness.
- Conditions
- Retinitis Pigmentosa, Usher Syndrome Type 2, Usher Syndrome Type 3
- Trial name
- NCT01530659
- Testing
- NT-501
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Neurotech Pharmaceuticals
Tinnitus, Hearing Loss
Neuro-feedback Therapy for Treating Tinnitus
Neuro-feedback for treating tinnitus seem to be a promising approach to help people suffering from chronic tinnitus. The past studies on this approach suffered interindividual variability in their results.
- Trial name
- TNTA (NCT03773926)
- Testing
- Neuro-feedback therapy
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Zeta Technologies
Conductive Hearing Loss, Conductive and Sensori-neural Hearing Loss in the Same Ear
Wide Diameter Bone Anchored Implant Study
To assess implant stability, implant loss, adverse skin reactions, and Quality of Life Benefit following implantation of the Ponto 4.5mm Wide Diameter implant.
- Conditions
- Conductive Hearing Loss, Conductive and Sensori-neural Hearing Loss in the Same Ear, Unilateral, Profound Sensori-neural Hearing Loss
- Trial name
- NCT01671176
- Testing
- Wide diameter bone anchored implant
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oticon Medical
Hearing Loss, Sensorineural
Quality Control of CE-Certified Phonak Hearing Aids - 2018_07
Phonak Hearing Systems pass through different development and study stages. At an early stage, feasibility studies are conducted to investigate new algorithms, features and functions in an isolated manner.
- Trial name
- NCT03555084
- Testing
- Extension of Virto B-Titanium, Virto B-Titanium
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- Sonova AG
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Conductive Hearing Loss, Mixed Hearing Loss
Evaluation of a Hearing Device for Transmitting Sound to the Inner Ear
A single center study evaluating the performance of an externally worn sound processor for a transcutaneous bone anchored hearing system using audiological outcomes measures such as aided thresholds and self-evaluation…
- Trial name
- NCT05628285
- Testing
- Sentio 1
- Where
- Sweden
- Volunteers
- 11 people
- Sponsor
- Oticon Medical
Hearing Loss, Sensorineural, Cochlear Implantation
Comparison of Performance Using MED-EL Automatic Sound Management
This study will evaluate the speech perception ability of adult cochlear implant users in background noise using various MED-EL Automatic Sound Management (ASM) features.
- Trial name
- NCT07500311
- Testing
- Automatic Sound Management Fixed Directionality, Automatic Sound Management Adaptive, Omnidirectional Settings
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Med-El Corporation
Conductive Hearing Loss
Comparison of a New Bone Conduction Hearing System to a Osteo-integrated Bone Conduction Hearing Aid on a Softband
Main objectives The first main objective is to evaluate the non-inferiority of the ADHEAR system compared to the PONTO 3 SUPERPOWER softband system in terms of average tonal gain.
- Trial name
- NCT03541967
- Testing
- ADHEAR and PONTO 3 SUPER POWER on softband hearing aids
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Severe-to-profound Hearing Loss
Benefits of the HiResolutionTM Bionic Ear System in Adults With Low-Frequency Hearing
The goal of this investigation is to generate the needed PMCF data for the HiFocus Mid-Scala electrode. As a point of interest the investigators would like to evaluate the benefit to patients with low-frequency residual hearing…
- Trial name
- NCT01824563
- Testing
- Observational study
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Advanced Bionics AG
Cisplatin Induced Hearing Loss
Study of OTO-104 in Subjects at Risk From Cisplatin-Induced Hearing Loss
This is a multicenter, Phase 2 study to assess the feasibility, safety and efficacy of OTO-104 given by intratympanic administration in subjects at risk for ototoxicity from cisplatin chemotherapy regimens in the treatment of…
- Trial name
- NCT02997189
- Testing
- OTO-104
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Otonomy, Inc.
Sensorineural Hearing Loss, Presbyacusis
First In Human Randomised Trial of Rincell-1 in Adults With a Cochlear Implant
Rinri Therapeutics is conducting a clinical trial of a new cell therapy called Rincell-1. Rincell-1 is being developed to treat adults with neural hearing loss, either age related hearing loss or auditory neuropathy, who also…
- Conditions
- Sensorineural Hearing Loss, Presbyacusis, Auditory Neuropathy
- Trial name
- NCT07032038
- Testing
- Otic neural progenitors, cochlear implantation
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Rinri Therapeutics
Bilateral Hearing Loss
Assessing Listening Effort at Different Signal-to-noise Ratios in Bone-anchored Users
The purpose of this study is to assess listening effort during a speech-in-noise task in bone-anchored hearing systems (BAHS) users via pupillometry.
- Trial name
- NCT04242940
- Testing
- Fitting of Ponto 4
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Oticon Medical
Hearing Loss
Pediatric Performance and Satisfaction of Oticon Medical Ponto on Softband.
The study is a non-interventional, observational, study on users of Ponto sound processors who use their sound processors on a softband solution.
- Trial name
- NCT06638840
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Oticon Medical
Acute Spinal Cord Injury
Phase 3 Study of KP-100IT in Subjects With Acute Spinal Cord Injury
This study is non-randomized, multicenter, confirmatory study by intrathecal administration of KP-100IT, code of HGF (Hepatocyte Growth Factor ) formulation for intrathecal injection, in subjects with acute spinal cord injury.
- Trial name
- NCT04475224
- Testing
- KP-100IT
- Where
- 5 sites in Japan
- Volunteers
- 25 people
- Sponsor
- Kringle Pharma, Inc.
Hearing Loss, Sensorineural Hearing Loss
Quality Control of CE-Certified Phonak Hearing Aids - 2018_42
Phonak Hearing Systems pass through different development and study stages. At an early stage, feasibility studies are conducted to investigate new algorithms, features and functions in an isolated manner.
- Trial name
- NCT03938753
- Testing
- Audéo M90-T
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Sonova AG
Cochlear Hearing Loss
Safety and Performance of HiRes Ultra/Ultra 3D Cl Mid-Scala Electrodes in Adults With Severe-to-profound Hearing Loss
This is a prospective study designed to evaluate the safety and performance of the HiRes Ultra Cl HiFocus MS Electrode and HiRes Ultra 3D Cl HiFocus MS Electrode (Ultra X) under normal conditions of use as it is approved for this…
- Trial name
- NCT04610112
- Testing
- Cochlear implantation
- Where
- 3 sites in Germany
- Volunteers
- 30 people
- Sponsor
- Advanced Bionics AG
Hearing Loss
First in Human Safety Study of FX-322 in Adults Undergoing Cochlear Implantation
This is a phase 1 safety study performed in male or female adult participants with an established diagnosis of severe to profound sensorineural hearing loss that meets the criteria for cochlear implantation and the participant…
- Trial name
- NCT03300687
- Testing
- FX-322
- Where
- Australia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Frequency Therapeutics
Acute Hearing Loss
Safety and Efficacy of STR001-IT and STR001-ER in Patients With SSHL
a multicenter, double-blind, placebo-controlled study in patients with Sudden Sensorineural Hearing Loss (SSHL). Patients will be treated with STR001 thermogel (STR001-IT) / STR001 tablets (STR001-ER) and corresponding Placebo on…
- Trial name
- NCT03331627
- Testing
- STR001-IT and STR001-ER
- Where
- 3 sites in Czechia, Germany and 1 more
- Volunteers
- 165 people
- Sponsor
- Strekin AG
Single Sided Deafness
Evaluation of Benefit for Treatment of Single Sided Deafness (SSD) Between Two Bone Conduction Prosthetic Devices; Osseointegrated Implant Versus Maxilla Anchored Removable Oral Appliance ("SoundBite")
The primary objective of this study is to compare the SoundBite™ Hearing System to surgically implanted BCD systems.
- Trial name
- NCT01933386
- Testing
- SoundBite
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Sonitus Medical Inc
Hearing Loss
Physiological, Behavioural and Subjective Measures of Listening Effort
Participants will perform two different listening tasks: (1) listening to, and repeating back, sentence lists presented in noise, and (2) listening to short radio excerpts and answering subsequent comprehension questions.
- Trial name
- NCT03761927
- Testing
- Hearing Aid without NR enabled, Hearing Aid with NR(1), Hearing Aid with NR(2)
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Sonova AG