Clinical trials: Headache, Post-Dural Puncture
Analgesia, Obstetrical, Post-Dural Puncture Headache
Intrathecal Catheter Placement Versus Resiting Epidural Catheter After Dural Puncture in Obstetric Patients
Epidural anesthesia represents the most popular method for pain relief during labour. Unintentional dural puncture (UDP) occurs in 0.4-1.5% of labour epidural analgesia, representing therefore the most common complication.
- Trial name
- ItaREVI (NCT05977361)
- Testing
- Resiting Epidural Catheter, Intrathecal Catheter Placement
- Volunteers
- 181 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Postdural Puncture Headache, Sphenopalatine Ganglion Block
Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
The investigators are attempting to determine a less invasive method of treatment for postdural puncture headaches that can occur after regional anesthesia.
- Trial name
- NCT02181205
- Testing
- bupivacaine
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Hypotension After Spinal Anesthesia, Post-Dural Puncture Headache
Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia
The prospective study is planned in a university hospital. Spinal anesthesia is widely used for cesarean section currently for its safety, low cost, reliability, easiness to administer, immediate effect, and well-operating…
- Trial name
- NCT05262933
- Testing
- coffee, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Post Dural Puncture Headache
Bedside Sedation for the Prevention of Post Dural Puncture Headache
Dural or lumbar puncture (LP), the passing of a needle into the space of the spinal cord, is a common procedure in everyday clinical practice.
- Trial name
- NCT01503788
- Testing
- Midazolam
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Post-Lumbar Puncture Headache
Headache After Diagnostic Lumbar Puncture
The objectives of this study are to investigate the effects of needle design, needle size and stylet reinsertion on the risk for headache after diagnostic LP (lumbar puncture, Post-LP headache).
- Trial name
- HELPUmeå (NCT03960749)
- Testing
- Sprotte 25G needle, stylet reinserted, Sprotte 25G needle, stylet not reinserted, Sprotte 22G needle, stylet reinserted
- Volunteers
- 1,000 people
- Sponsor
- Jonatan Salzer
Cesarean Section, Anesthesia, Obstetrical
Dural Puncture Epidural With 27G vs 26G Needles Versus Standard Epidural for Elective Cesarean Delivery
The goal of this clinical trial is to learn whether the dural puncture epidural (DPE) technique shortens the onset time of surgical anesthesia compared with the standard epidural technique in healthy women undergoing elective…
- Conditions
- Cesarean Section, Anesthesia, Obstetrical, Anesthesia, Epidural
- Trial name
- NCT07897045
- Testing
- Standard Epidural Anesthesia, Dural Puncture Epidural With 27G Spinal Needle, Dural Puncture Epidural With 26G Spinal Needle
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ankara City Hospital Bilkent
Parturients in Labour
Alteration in Hearing Following Accidental Dural Puncture. A Study in Parturients
Headache following accidental dural punction as during epidural analgesia can be severe and sometimes very disabling. The incidence of PDPH is 10-40%, most starting within 48 h of dural puncture.
- Trial name
- AHEAD (NCT01682967)
- Where
- 2 sites in Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Headache
Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture Headache
We hypothesized that; intrathecal administration of neostgmine in spinal anesthesia may have a beneficial role in reduction of the incidence or severity of PDPH.
- Trial name
- NCT04905953
- Testing
- Neostigmine
- Where
- Egypt
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postdural Puncture Headache
Spenopalatine Ganglion Block for Treatment of Post-dural Puncture Headaches
Postdural puncture headache (PDPH) is a severe, debilitating complication of dural puncture that can arise from insertion of an epidural or spinal needle for labour analgesia.
- Trial name
- SPGB (NCT04515901)
- Testing
- 2% lidocaine
- Where
- Canada
- Sponsor
- McMaster University
Lumbar Puncture
Ultrasound-assisted vs Palpation-guided Lumbar Punctures
The goal of this randomized clinical trial is to determine whether ultrasound-assisted lumbar puncture improves first-needle insertion success compared with the standard palpation technique in adults undergoing a clinically…
- Trial name
- NCT07824284
- Testing
- Ultrasound-Assisted Lumbar Puncture, Standard Palpation-Guided Lumbar Puncture
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- The Cooper Health System
Post-Dural Puncture Headache
Effect of Altitude on Postdural Puncture Headache After Caesarean Delivery
The aim of this study is to examine the effects of altitude (high altitude versus low altitude) on incidence and severity of postural puncture headache (PDPH) following spinal anaesthesia for caesarean delivery.
- Trial name
- NCT05804448
- Where
- 2 sites in Nepal
- Volunteers
- 292 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Intracranial Hypotension
The Blood Patch in the Management of Intracranial Hypotension
Intracranial hypotension results from leakage and/or hypotension of cerebrospinal fluid. It can be spontaneous or secondary to a dural puncture complicating perimedullary anesthesia or a lumbar puncture.
- Trial name
- BPIH (NCT06498804)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Headache
Postdural Puncture Headache After Spinal Anesthesia for Cesarean Section
Post-dural puncture headache (PDPH) is a potential and debilitating complication of spinal anesthesia in pregnant patients undergoing caesarean sections (CS), with a reported incidence of 0.5%-2% .
- Trial name
- NCT06683807
- Testing
- Hyperbaric bupivacaine 0.5% (2.5 mL) aspirated immediately after opening the bupivacaine ampule, Hyperbaric bupivacaine 0.5% (2.5 mL) aspirated 5 minutes delayed after opening the bupivacaine ampule
- Volunteers
- 55 people
- Sponsor
- Assiut University
Postdural Puncture Headache
Aminophylline Prophylaxis For Postdural Puncture Headache
postdural puncture headache is a rare but serious complication of spinal anesthesia. many drugs were studied in prevention or treatment of that complication.
- Trial name
- NCT02150304
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Plasma Rich Fibrin, Epidural
Plasma Rich Fibrin Epidural Injection by Racz Catheter in Postdural Puncture Headache Guided Optic Nerve Sheath Diameter
This study aims to evaluate plasma-rich fibrin epidural injection by Racz catheter in post-dural puncture headaches guided optic nerve sheath diameter.
- Conditions
- Plasma Rich Fibrin, Epidural, Racz Catheter, Postdural Puncture Headache
- Trial name
- NCT06790758
- Testing
- Plasma rich fibrin epidural injection by Racz catheter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Post-Dural Puncture Headache
Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Patients Undergoing Infraumbilical Surgeries
Post-dural puncture headache (PDPH) or spinal (or post-spinal) headache is one of the most common side effects of spinal anesthesia, with an incidence of 6-36%.
- Trial name
- NCT06729047
- Testing
- normal Saline, Neostigmine, Ketorolac
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Assiut University
Headache Disorders, Secondary, Post-Dural Puncture Headache
Association Between Chronic Headache and Back Pain With Childbirth
This study uses a single questionnaire to evaluate two separate primary outcomes: 1. To identify association between chronic headache in women who have given birth to children as compared to a control group of women who have…
- Conditions
- Headache Disorders, Secondary, Post-Dural Puncture Headache, Migraine Disorders, Back Pain
- Trial name
- NCT04091321
- Where
- United States
- Volunteers
- 1,112 people
- Sponsor
- Stanford University
Post Dural Puncture Headache
Caffeine Versus Placebo for Spinal Headaches
Caffeine will be studied against placebo in patients with positional headache after a lumbar puncture (aka "spinal headache").
- Trial name
- NCT00809627
- Testing
- Caffeine, saline
- Where
- United States
- Sponsor
- United States Naval Medical Center, Portsmouth