Clinical trials: Headache (Migraine)
Migraine Disorders
Chronic Migraine Epidemiology and Outcomes Study
This is a population internet-based study to characterize migraine clinical course and impact on family.
- Trial name
- NCT01648530
- Testing
- No Treatment
- Volunteers
- 16,789 people
- Sponsor
- Allergan
Migraine
Effectiveness and Neural Mechanism of Naoan Dripping Pills for Migraine
This is a randomized, double-blind, placebo-controlled clinical trial. Its main purpose is to investigate the effects and neural mechanism of Naoan dripping pills on migraine patients by utilizing fMRI and DTI method, as well as…
- Trial name
- ENMNM (NCT03175900)
- Testing
- Naoan dripping pills
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dongzhimen Hospital, Beijing
Migraine Disorders, Obesity
A Pilot Study of Migraine and Appetite Behaviour in Children
The purpose of this study is to determine whether there is an association between migraine in children and certain patterns of appetite or eating behaviour that may lead to later obesity.
- Trial name
- NCT00930852
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Migraine Headache
A Study to Measure the Safety and Effectiveness of Zonisamide in Subjects With Migraine Headache
The purpose of this study is to determine if zonisamide is effective as a preventative medication for individuals with migraine headache.
- Trial name
- NCT00055484
- Testing
- zonisamide
- Where
- 13 sites in United States
- Volunteers
- 204 people
- Sponsor
- Elan Pharmaceuticals
Chronic Migraine
Study of MIGRA-ZEN RELIEF PLUS In the Treatment of Chronic Migraine Headache
The purpose of this study is to study MIGRA-ZEN RELIEF PLUS, an all-natural herbal dietary supplement product, with respect to alleviating and/or stopping migraine headache pain compared to a placebo when used prophylactically.
- Trial name
- RZN (NCT01135784)
- Testing
- MIGRA-ZEN RELIEF PLUS
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- RZN Nutraceuticals, Inc.
Migraine Disorders
Potential Osteocatabolic Effect Caused by Anti-CGRP mAbs in Migraine Patients Treated With Anti-CGRP mAbs - an Observational Pilot Project With Prospectively Collected Health Related Data
Background: To gain insight on the osteoanabolic activity of anti-CGRP mAbs in patients with migraine as this was not yet specifically investigated in registration or post-approval clinical studies, however, being…
- Trial name
- NCT06035458
- Testing
- Diagnostic radiology
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Acute Migraine
Migraine Treatment With Nerivio Migra Neurostimulation Device
This is a prospective, randomized, double-blind, sham controlled multi-center trial. Ratio between treatment and control groups will be 1:1, stratified by center and use of preventive medications.
- Trial name
- NCT03076515
- Testing
- Nerivio Migra neurostimulation
- Where
- 8 sites in United States, Israel
- Volunteers
- 120 people
- Sponsor
- Theranica
Migraine, Headache Disorders, Primary
Efficacy of Greater Occipital Nerve Radiofrequency for Refractory Migraine Treatment
Objective: Ultrasound-guided pulsed radiofrequency therapy can be used on the greateroccipital nerve (GON) in patients with chronic migraine (CM) who are unresponsive to conservative treatments.
- Trial name
- NCT05199064
- Testing
- Ultrasound guided greater occipital nerve (GON) radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Chronic Headache
Integrated Care for Migraine and Chronic Tension-type Headaches
Chronic headache is among the most common neurological disorders with major physical, psychological, social and economic impact.
- Trial name
- IV (NCT03503734)
- Testing
- Integrated headache care
- Where
- Germany
- Volunteers
- 158 people
- Sponsor
- Universität Duisburg-Essen
Migraine
Metoclopramide for Migraine: A Dose Finding Study
Metoclopramide is an effective intravenous treatment for acute migraine attacks, but we do not know the best dose to administer. This study compares three different doses of metoclorpamide.
- Trial name
- MDFS (NCT00682734)
- Testing
- metoclopramide, Diphenhydramine 25mg
- Where
- United States
- Volunteers
- 349 people
- Sponsor
- Montefiore Medical Center
PMS, Menstrual Cramp
A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome
This virtual, randomized, placebo-controlled clinical trial evaluates the effectiveness of a PMS capsule and PMS gummy in alleviating premenstrual syndrome symptoms over 12 weeks.
- Conditions
- PMS, Menstrual Cramp, Mood Change
- Trial name
- NCT06763809
- Testing
- PMS Capsule, PMS Gummy
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Semaine Health
Migraine
Omega-3 Supplementation for Pediatric Migraine
The purpose of the study is to assess the biochemical and clinical effects of omega-3 polyunsaturated fatty acid (PUFA) supplementation in youth suffering from migraine, including its effects on migraine disability, psychological…
- Trial name
- NCT06899074
- Testing
- Omega 3 Polyunsaturated Fats
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Migraine
PSG and Neuroendocrine Hormones in Subjective Cognitive Impaired Patients With Transformed Migraine
Transformed migraine is the most common and challenging subtype of chronic daily headache disorders35. Patients with transformed migraine often report an evolutionary process that occurs over months or years in which headaches…
- Trial name
- NCT04413110
- Testing
- Polysomnography
- Where
- Egypt
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Headache
The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine
This study compares the efficacy of low dose Ketamine versus Compazine for the control of headache in patients presenting to the Emergency Department.
- Trial name
- NCT02657031
- Testing
- Prochlorperazine, Ketamine, Diphenhydramine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University Medical Center of Southern Nevada
Migraine Disorders
Safety Tolerability and Pharmacokinetics of ALD403
The purpose of this study is to determine the safety, tolerability and pharmacokinetics of ALD403, a monoclonal antibody, administered by intravenous infusion and subcutaneous injection.
- Trial name
- NCT01579383
- Testing
- ALD403, Sumatriptan
- Where
- Australia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Alder Biopharmaceuticals, Inc.
Migraine
Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Multiple Dosing Regimens
The purpose of this study is to compare the efficacy and safety of daily and every other day dosing of rimegepant to placebo as a preventive treatment for episodic migraine.
- Trial name
- NCT05217927
- Testing
- Rimegepant 75mg daily dosing, Rimegepant 75mg every other day dosing
- Where
- 107 sites in United States, Austria and 8 more
- Volunteers
- 1,415 people
- Sponsor
- Pfizer
Migraine
A Trial to Study of the Effects of Eletriptan 40mg on Mild vs Moderate to Severe Pain Intensity of Migraine
To evaluate the efficacy of early intervention (dosing within 2 hours of onset of the migraine attack) with eletriptan 40mg on mild versus moderate to severe pain intensity of migraine.
- Trial name
- NCT00174395
- Testing
- eletriptan
- Where
- 33 sites in Canada
- Volunteers
- 220 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Migraine
Psychosomatic Factors Influencing the Efficacy of Holistic Care for Migraine
This research project aims at exploring the psychosomatic factors that influence and moderate the efficacy of holistic care and personalized treatment for migraine patients. It is a prospective longitudinal observational study.
- Trial name
- NCT06334237
- Testing
- personalized treatment
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Changhua Christian Hospital
Migraine, Depression
Treatment for Migraine and Mood (Team-M)
The researchers propose a two-arm pilot study of telephone and video delivered Mindfulness-based Cognitive Therapy (MBCT-T and MBCT-V) in people with migraine and depressive symptoms.
- Trial name
- TEAM-M (NCT04992494)
- Testing
- MBCT-Telephone, MBCT-Video
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- NYU Langone Health
Episodic Migraine, Migraine Disorders
My Healthy Diary - An Electronic Diary for Remote Migraine Monitoring
This study aims to evaluate the usefulness of an app-based headache diary in episodic migraine patients. For this the investigators will conduct a randomized clinical trial with a crossover design, using the app-based diary and a…
- Trial name
- E-Migra (NCT04828941)
- Testing
- Electronic Headache Diary, Paper Diary
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Unidade Local de Saúde de Matosinhos, EPE
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