Clinical trials: Headache (Migraine)
Migraine Disorders
Reliability of Rimegepant or Triptans for the Acute Treatment of Migraine
This protocol describes the analysis of the Adelphi Real World (ARW) Migraine Disease Specific Programme(TM) 2022, a cross-sectional study which used both physician and patient surveys to assess the perception of the acute…
- Trial name
- Adelphi DSP (NCT06412965)
- Where
- United States
- Volunteers
- 528 people
- Sponsor
- Pfizer
Chronic Headache
Project CHEER (Comprehensive Headache Evaluation, Education, Relief)
PROJECT CHEER is a randomized controlled trial designed to test the effectiveness of a comprehensive focused approach to headache care.
- Trial name
- NCT00417742
- Testing
- Service delivery through a Headache Management Program
- Where
- 3 sites in United States
- Volunteers
- 828 people
- Sponsor
- Duke University
Migraine Disorders, Obesity
A Pilot Study of Migraine and Appetite Behaviour in Children
The purpose of this study is to determine whether there is an association between migraine in children and certain patterns of appetite or eating behaviour that may lead to later obesity.
- Trial name
- NCT00930852
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Chronic Migraine
Treximet in the Treatment of Chronic Migraine
This study is being conducted to evaluate the hypothesis that use of Treximet in patients with chronic migraine, when used on a short term daily basis and as rescue for break through attacks, will reduce migraine frequency and…
- Trial name
- NCT01090050
- Testing
- Sumatriptan/Naproxen Sodium, Naproxen Sodium
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- Cady, Roger, M.D.
Migraine
Clinical Effectiveness of Osteopathic Manipulative Treatment in Chronic Migraine
The aim of the present study is to determine the extend to which OMT is effective on a sample of subjects affected by migraine evaluated using the headache impact test (HIT-6) questionnaire.
- Trial name
- NCT01851148
- Testing
- osteopathic manipulative treatment, triptans
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Pain, Head Pain
Aromatherapy Massage in Migraine Attacks
The aim of the study was to determine the effect of aromatherapy massage on the pain severity and quality of life in patients diagnosed with migraine in addition to medical treatment during an acute migraine attack.
- Conditions
- Pain, Head Pain, Quality of Life
- Trial name
- NCT04151576
- Testing
- aromatherapy massage
- Volunteers
- 83 people
- Sponsor
- Biruni University
Chronic Migraine, Medication Overuse Headache
Mindfulness Therapy for Chronic Migraine
The aim is to assess the efficacy of adding on a Mindfulness-based therapy to pharmacological prophylaxis (experimental group: pharmacological prophylaxis + Mindfulness) against pharmacological prophylaxis only (control group) on…
- Trial name
- Mind-CM (NCT03671681)
- Testing
- Mindfulness, Prophylactic
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Migraine
Migraine Treatment Satisfaction With Treximet Versus Concomitant 2 Aleve and Imitrex
This is an open label, 6 month cross over study in 50 migraine patients fulfilling International Headache Society Classification criteria for migraine headache with and without aura having 2-6 migraines per month and not over 14…
- Trial name
- NCT01450995
- Testing
- Treximet, Imitrex and two Aleve
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stephen H. Landy, M.D.
Acute Migraine
Long-term Safety Study of BHV-3500 (Zavegepant*) for the Acute Treatment of Migraine
The purpose of this study is to evaluate the long-term safety of BHV-3500/vazegepant intranasal in the acute treatment of migraine. BHV-3500, formerly "vazegepant", is now referred to as "zavegepant" (za ve' je pant).
- Trial name
- NCT04408794
- Testing
- Zavegepant (BHV-3500)
- Where
- 67 sites in United States
- Volunteers
- 974 people
- Sponsor
- Pfizer
PFO - Patent Foramen Ovale, Migraine
COMPETE Cohort Study
Migraine attacks are episodic disorder that affects approximately 12% of the population, and studies have shown that 41-48% of migraineurs have a combination of patent foramen ovale (PFO).
- Trial name
- NCT06033937
- Testing
- PFO occlusion
- Where
- China
- Volunteers
- 242 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Migraine, Patent Foramen Ovale
Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale
To establish a headache center in China that combines clinical, imaging and laboratory examinations, explore the feasible treatment options for migraine combined with patent foramen ovale, and search for the possible influencing…
- Trial name
- NCT06953622
- Testing
- Conservative treatment, Antipaletet drug, Patent Foramen Ovale Closure
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Peking University Third Hospital
Migraine Disorders, Headache Disorders
Idebenone for the Preventive Treatment of Migraine
Idebenone improves energy metabolism similarly to Coenzyme Q10, which is effective in migraine prophylaxis. The investigators compare idebenone (90 mg/day, 270 mg/day) and placebo in 180 migraine patients in a double-blind…
- Trial name
- NCT04151472
- Testing
- 90mg Idebenone, 270mg Idebenone
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Migraine, Depressive Symptoms
Treatment for Migraine and Mood
The researchers propose a three-arm pilot study of Mindfulness-Based Cognitive Therapy (MBCT) delivered via telephone (MBCT-T), video (MBCT-V) or Enhanced Usual Care (EUC).
- Trial name
- TEAM-M (NCT05576467)
- Testing
- MBCT-Telephone, MBCT-Video, Enhanced Usual Care (EUC)
- Where
- 3 sites in United States
- Volunteers
- 145 people
- Sponsor
- Amanda Shallcross
Episodic Migraine Headache
Craniocervical Flexion Training for Reducing Migraine Headaches and Disability
Migraine, a leading cause of disability globally, necessitates effective interventions beyond pharmacotherapy due to the associated risks.
- Trial name
- NCT06751732
- Testing
- Craniocervical Flexion Training (CCFT), Diaphragm Respiratory Training, Cervical Mobilization and Traction
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Migraine
Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care
This study, which is aimed at comparing the effectiveness of the most frequently used drugs in the first line in primary care for the preventive treatment of migraine (amitriptyline, flunarizine, topiramate and propranolol), is a…
- Trial name
- PREMI (NCT06499116)
- Testing
- Topiramate, Flunarizine, Amitriptyline
- Volunteers
- 460 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Nummular Headache, Migraine
Observational Prospective Study on the Presence of Typical Migraine Features in Nummular Headache Patients: The Numamig Study
Observational analytic study with prospective cohort design that aim to describe the presence of typical features of migraine in a cohort of nummular headache patients.
- Conditions
- Nummular Headache, Migraine, Headache Disorders, Primary
- Trial name
- NCT04299958
- Testing
- Patient diary
- Where
- Spain
- Volunteers
- 19 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Headache, Migraine
Headache Inducing Effect of Levcromakalim in Migraine With Aura Patients
To investigate the role of KATP channels in migraine with aura patients.
- Conditions
- Headache, Migraine, Aura
- Trial name
- NCT04012047
- Testing
- Levcromakalim, Saline
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- Danish Headache Center
Migraine Disorders
Lippia Alba for Migraine Prophylaxis and Treatment
Abstract Background: There is no universally accepted and effective prophylaxis of migraine headache episodes. Thus the investigators aimed to investigate the effects of Lippia alba (Mill.) N. E.
- Trial name
- NCT01259947
- Testing
- Lippia alba (Mill.) N. E. Brown ethanolic extract
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Fabio Carmona
Gulf War Illness, Persian Gulf Syndrome
Exercise in Gulf War Illness (GWI)
The purpose of this study is to determine if submaximal exercise by bicycle stress tests with pulmonary measurement of VO2MAX plus maximal isometric hand grips on 2 consecutive days causes a higher level of "exertional…
- Trial name
- NCT01291758
- Testing
- Submaximal bicycle exercise stress tests performed 24 hr apart
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Migraine Disorders
Migraine Attack Treatment Response Molecular and Clinical BiOmarkers (MAMBO) Phase I
The goal of this observational study is to identify differential traits in spontaneous migraine attacks that can help us predict the response to treatment with sumatriptan.
- Trial name
- MAMBO (NCT06503848)
- Testing
- Sumatriptan
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
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