Clinical trials: Headache (Migraine)
Migraine
Real-World Evidence (RWE) Data Analysis of 1-year Consecutive Use of Remote Electrical Neuromodulation (REN)
This is a Post-marketing study investigating the long-term safety, utilization, and efficacy of REN during 12 consecutive months of using Nerivio in migraine patients.
- Trial name
- NCT05760638
- Testing
- Nerivio
- Where
- 2 sites in United States, Israel
- Volunteers
- 409 people
- Sponsor
- Theranica
Headache Disorders, Primary, Prevalence
Headache in Undergraduate Students and Biopsychosocial Status
The primary aim of this study was to determine the prevalence of headache in undergraduate students. The frequency, duration, localizations and symptoms of headache will be determined with the information obtained as a result of…
- Conditions
- Headache Disorders, Primary, Prevalence, Migraine, Student
- Trial name
- NCT05843760
- Testing
- personal information form, headache-specific questionnaires, Questionnaires for assessing biopsychosocial status
- Where
- Turkey (Türkiye)
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- şeyda öztürk
Migraine Disorders
Management of Migraine Using Enerumab and Traditional Therapy at the Time of COVID-19
The objective of this study was to assess the efficacy of erenumab on frequency of monthly migraine days in adults at baseline, 3 months and 6 months, disability in patients with chronic migraine and on post covid migraine…
- Trial name
- NCT05052008
- Testing
- Erenumab
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Fayoum University
Migraine
Prospective Survey of Menstrual Migraine & Prevention With Eletriptan
Women are followed prospectively for 3 months, recording headaches, other symptoms, and menstrual periods. Those with menstrual migraine are treated perimenstrually with eletriptan for 3 months.
- Trial name
- NCT00259649
- Testing
- eletriptan
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Migraine
A Dose-Finding Study of MK-1602 in the Treatment of Acute Migraine (MK-1602-006)
The purpose of this study is to assess the effectiveness, safety and tolerability of a range of doses of MK-1602 versus placebo in the treatment of acute migraine.
- Trial name
- NCT01613248
- Testing
- MK-1602, Rescue medication
- Volunteers
- 834 people
- Sponsor
- Allergan
Headache Disorders, Influenza -Like Illness
InfluenCEF Study: Study on the Headache Associated With Influenza Infection
The goal of this observational analytic study with a cohort desing is to evaluate the epidemiology, risk factors and clinical phenotype of headache during Influenza infection.
- Conditions
- Headache Disorders, Influenza -Like Illness, Head Pain, Migraine
- Trial name
- INFLUENCEF (NCT05704335)
- Testing
- Questionnaire administration
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Migraine
Comparative Efficacy of Flunarizine and Propanolol in Pediatric Migraine
Flunarizine and propranolol have demonstrated efficacy in reducing migraine frequency across age groups, though evidence in pediatric populations remains limited and inconsistent.
- Trial name
- NCT07354126
- Testing
- Flunarizine, Propranolol
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Muhammad Aamir Latif
Migraine
Influence of Ubrogepant and Sumatriptan on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin
The involvement of calcitonin gene-related peptide (CGRP) in the cinnamaldehyde-induced dermal blood flow increase and in the mechanism of action of triptans will be investigated.
- Trial name
- NCT05654298
- Testing
- Sumatriptan, Ubrogepant
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Migraine Disorders, Headache Disorders, Primary
Individualized Prediction of Migraine Attacks Using a Mobile Phone App and Fitbit
This trial is collaboration between Mayo Clinic, Second Opinion Health (Simon Bloch, simon@somobilehealth.com 408-981-3814) and Allergan.
- Conditions
- Migraine Disorders, Headache Disorders, Primary, Headache Disorders, Brain Diseases
- Trial name
- Migraine Alert (NCT02910921)
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Second Opinion Health
Migraine, Greater Occipital Nerve Pulsed Radiofrequency, Headache Disorders
Comparing Unilateral and Bilateral Proximal GONPRF in Migraine Treatment
This study is designed to compare the clinical effectiveness of unilateral and bilateral Greater Occipital Nerve Pulsed Radiofrequency (GON-PRF) treatment at the C2 level in patients with migraine.
- Conditions
- Migraine, Greater Occipital Nerve Pulsed Radiofrequency, Headache Disorders, Ultrasound Guided Nerve Block
- Trial name
- (UBGON-PRF) (NCT06894121)
- Testing
- Greater Occipital Nerve Pulsed Radiofrequency (Unilateral), Bilateral GON PRF Treatment:
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people
- Sponsor
- Ankara City Hospital Bilkent
Migraine
The Effects of Lasmiditan on Simulated Driving Performance - Healthy Participants
This will be a randomized, single dose, double-blind, placebo-controlled, Latin-square design with 5-period (full) crossover study with participants randomized to treatment sequences. Participants will complete all 5 Periods.
- Trial name
- NCT03012334
- Testing
- Lasmiditan, Alprazolam
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Migraine, Migraine Disorders
Real-world Effectiveness and Tolerability of Triptans-Ditans-Gepants (TRIDIGEP)
Migraine is the third most prevalent disease and the leading reason of years lived with disability in the most productive years of the life. Migraine associated disability can be alleviated by acute and preventive treatment.
- Conditions
- Migraine, Migraine Disorders, Migraine With Aura, Headache Disorders
- Trial name
- TRIDIGEP (NCT06267664)
- Testing
- Patients with migraine treated with triptans, Lasmiditan or Gepants
- Where
- Spain
- Volunteers
- 1,500 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Migraine
Biomarker and Genetic Predictors of Erenumab Treatment Response
To explore the relationship between clinical response to erenumab and genetic biomarkers
- Trial name
- INTERROGATE (NCT04265755)
- Testing
- Erenumab
- Where
- 2 sites in Denmark, Iceland
- Volunteers
- 1,406 people
- Sponsor
- Amgen
Migraine
Research Study of Greater Occipital Nerve Block As A Treatment For Prolonged Migraine Attacks
Greater Occipital Nerve Blocks (GONB) are a common procedure used for the treatment of headache. The GONB procedure involves a series of injections into the greater occipital nerve (a spinal nerve located at the back of your…
- Trial name
- NCT00329732
- Testing
- 0.5% bupivicaine and 2% lidocaine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Thomas Jefferson University
Migraine, Migraine Disease
Effects of Progressive Muscle Relaxation Training Applied in Addition to Aerobic Exercise Training in Individuals With Migraine Diagnosis
Aim: The purpose of this study is to evaluate the effects of progressive muscle relaxation training, in addition to aerobic exercise training, on pain, disability, quality of life, psychological status, and functional capacity in…
- Trial name
- NCT07003711
- Testing
- aerobic exercise and relaxation trainig, aerobic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Mardin Artuklu University
Headache
Facilitating Migraine Medication Adherence and Optimizing Medication Use
The present research will pilot-test a new state-of-the-art Internet-based intervention targeting adherence facilitation and optimization of medication use, and will be evaluated to assess its utility in facilitating adherence…
- Trial name
- NCT02473692
- Testing
- Online Migraine Treatment Optimization
- Sponsor
- Wake Forest University Health Sciences
Migraine, Exercises
Effect of a Home-based Versus Supervised Exercise Program in Patients With Migraine
Migraine is a common primary headache with documented impacts on the patient, the economy, and society. A growing number of studies have reported that people with migraines are more likely to experience neck pain and neck…
- Trial name
- NCT05292599
- Testing
- Experimental, Control
- Where
- Argentina
- Volunteers
- 40 people
- Sponsor
- University of Gran Rosario
Migraine
Single Ascending Dose Study to Investigate the Safety and Pharmacokinetics of XC101-D13H in Healthy Adult Subjects
This is a randomized, double-blind, placebo-controlled, parallel-group single ascending dose (SAD) study. There are 4 cohorts of 8 subjects (8 active and 2 placebo) planned for evaluation under fasting conditions.
- Trial name
- NCT04104399
- Testing
- XC101-D13H
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Xoc Pharmaceuticals
Migraine, Common Migraine
A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine
The purpose of this study is to evaluate the safety and efficacy of three doses of topiramate (50 milligrams[mg], 100mg, and 200mg taken daily) compared with placebo in the prevention of migraine.
- Conditions
- Migraine, Common Migraine, Classic Migraine, Headache
- Trial name
- NCT00236509
- Testing
- topiramate
- Volunteers
- 763 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Migraine
DP-VPA for Migraine Prophylaxis, a Pilot Efficacy Study
The study will evaluate if DP-VPA, a derivative of valproate (a drug that is commonly used for the prevention of migraine attacks), can reduce the rate of migraine attacks.
- Trial name
- NCT00640965
- Testing
- DP-VPA
- Where
- 6 sites in Israel
- Volunteers
- 40 people
- Sponsor
- D-Pharm Ltd.
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