Clinical trials: Headache (Migraine)
Migraine, Omega-3 Polyunsaturated Fatty Acids
Omega-3 Fatty Acid in the Prevention of Migraine
To understand the clinical efficacy for omega-3 PUFAs migraine prevention.To uncover the underlying biochemical or neurophysiological mechanisms by which omega-3 PUFAs for migraine prevention.
- Trial name
- NCT04572789
- Testing
- Omega-3 polyunsaturated fatty acids, omega-6 PUFAs
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kuang Tien General Hospital
Migraine
Evaluation of MIG-SPRAY Treatment on Migraine
The goal of this clinical trial is to evaluate the real-world tolerability of the MIG-SPRAY device in adults aged 18-55 diagnosed with migraine (according to nternational Classification of Headache Disorders 3rd edition, code…
- Trial name
- MIG-S (NCT07100496)
- Testing
- MIG-SPRAY
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Clermont-Ferrand
Migraine, Cluster Headache
Saccadometry in Primary Headache Syndromes
Migraine is one of the commonest neurological disorders, affecting up to 12% of the general population, but remains relatively under-diagnosed and under-treated.
- Conditions
- Migraine, Cluster Headache, Control, Menstrual Migraine
- Trial name
- NCT01395264
- Where
- 2 sites in United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tim Young
Transformed Migraine, Chronic Daily Headache
Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines
This study will compare a local anesthetic technique that has been used to treat subjects suffering from transformed migraines (chronic migraines) versus medical management with traditional antidepressant Amitriptyline / Elavil.
- Trial name
- NCT02090998
- Testing
- SPG Block with 5% Lidocaine gel, Amitriptyline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Rutgers, The State University of New Jersey
Migraine
Vagal Nerve Stimulation and Pain Frequency, Intensity in Chronic Migraine
This study is being conducted to address the need for effective and well-tolerated interventions in preventing chronic migraine attacks.
- Trial name
- NCT06191016
- Testing
- Vagal nerve stimulation
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Riphah International University
Migraine With Aura, Stroke
Induction of Migraine Aura With Cilostazol
In a double blind placebo-controlled cross-over study the effect of cilostazol on aura induction and endothelial response is tested in patient with migraine with aura.
- Trial name
- NCT02253004
- Testing
- Cilostazol
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Herlev Hospital
Migraine
Hypersensitivity to CGRP as a Predictive Biomarker of Migraine Prevention With Erenumab
To explore the relationship between clinical response to erenumab and response to intravenous infusion of calcitonin gene-related peptide in individuals with migraine.
- Trial name
- NCT04592952
- Testing
- Calcitonin Gene-Related Peptide, Erenumab
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Danish Headache Center
Migraine
Assessment of Safety and Efficacy of Nerivio for the Migraine Prevention
Migraine is a common neurologic with attacks of headache and associated symptoms such as nausea, vomiting, phono and photophobia. Migraine can lead to substantial functional impairment.
- Trial name
- NCT04828707
- Testing
- Nerivio active device
- Where
- 16 sites in United States
- Volunteers
- 335 people
- Sponsor
- Theranica
Headache (Migraine)
Prevalence and Determinants of Migraine Among Headache Patients
Migraine is a prevalent and disabling neurological condition that often coexists with other health issues, such as hypertension and impaired physical, mental, and social functioning.
- Trial name
- NCT07038499
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Universiti Tunku Abdul Rahman
Migraine
Study to Test an Approved Product in the Early Treatment of Migraine (0462-066)
The purpose of this study is to test the effectiveness of an approved drug in the early treatment of migraine.
- Trial name
- NCT00095004
- Testing
- MK0462, rizatriptan benzoate / Duration of Treatment: 1day
- Volunteers
- 167 people
- Sponsor
- Organon and Co
Migraine
Efficacy and Safety Trial of Rimegepant for Migraine Prevention in Adults
The purpose of this is study is to compare the efficacy of BHV-3000 (rimegepant) to placebo as a preventive treatment for migraine, as measured by the reduction in the number of migraine days per month.
- Trial name
- NCT03732638
- Testing
- Rimegepant
- Where
- 93 sites in United States
- Volunteers
- 1,590 people
- Sponsor
- Pfizer
Migraine Headaches
Study to Determine the Efficacy and Safety of ELS-M11 in Acute Migraine
This is a Phase 1/ Phase 2, 12-week, multi-center, randomized, double-blind, cross-over, placebo-controlled study to evaluate the efficacy and safety of ELS-M11 compared to placebo in 50 male and female subjects, aged 18 to 65…
- Trial name
- NCT02057315
- Testing
- ELS-M11
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Achelios Therapeutics
Primary Headache Disorder
Gender Differences and Features of the Clinical Course of Primary Headaches
The pathophysiological mechanisms that underlie primary headache disorders, such as migraine and cluster headache (CH), are complex and not yet fully clarified.
- Trial name
- NCT05760625
- Testing
- analysis BDNF
- Where
- Uzbekistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tashkent Medical Academy
Migraine Headache
Testing myWHI: Online Self-guided Programs for Migraine
The goal for this pilot study is to assess the acceptability of two online self-guided programs for migraines. The programs are part of the investigators' collection of "my Wireless Headache Interventions" (myWHI).
- Trial name
- NCT02710942
- Testing
- SPHERE, PRISM
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- IWK Health Centre
Migraine
Efficacy and Safety of Subcutaneous Administration of Fremanezumab (TEV-48125) for the Preventive Treatment of Migraine
A study to evaluate the long-term safety, tolerability, and efficacy of subcutaneous (SC) administration of TEV-48125 in adult participants with chronic migraine (CM) or episodic migraine (EM).
- Trial name
- HALO (NCT02638103)
- Testing
- Fremanezumab
- Where
- 139 sites in United States, Canada and 7 more
- Volunteers
- 1,890 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Migraine Disorders
Cognitive Function and Autonomic Regulation in Patients With Migraine
Individuals with migraine have impaired cognitive function and worse autonomic function compared to individuals without migraine.
- Trial name
- NCT04272229
- Testing
- Cognition, Sympathetic Nervous System, Concentratio and Attention
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fortaleza University
Headache, Migraine
Study on Indomethacin-responsive Headaches
Description of modalities concerning the patient care of headaches sensible to indometacine.
- Trial name
- NCT03967483
- Testing
- Indometacin
- Volunteers
- 100 people
- Sponsor
- Anne Ducros
Migraine
Determine Central 5-HT1B Receptor Occupancy of ZOMIG® Rapimelt (Zolmitriptan) in Healthy Male Volunteers
The purpose of this study is to determine the central 5-HT1B receptor occupancy of ZOMIG® Rapimelt (zolmitriptan) in healthy male volunteers.
- Trial name
- NCT01085123
- Testing
- Rapimelt, [11C]AZ10419369
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Menstrual Migraine
An Investigation of the Safety and Utility of Treximet in the Treatment of Menstrual Migraine
The study is to primarily investigate whether Treximet® (Imitrex RT/naproxen sodium 500mg) taken at the first onset of menstrual migraine will both terminate the acute headache and assist in preventing headache recurrence and the…
- Trial name
- NCT01578941
- Testing
- Diary
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Alabama at Birmingham
Migraine
Study of Oral Lasmiditan in Participants With Normal and Impaired Renal Function
This is a multi-center, open-label, non-randomized, parallel-group, adaptive, single dose study. This study will enroll up to 32 participants using an adaptive design that can include up to 3 groups of 8 participants with…
- Trial name
- NCT03009162
- Testing
- Lasmiditan
- Where
- 2 sites in Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
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