Clinical trials: Headache (Migraine)
Migraine Disorders
Non-steroidal Anti-inflammatory Drugs Alone or With a Triptan and Reports of Transition From Episodic to Chronic Migraine
Chronic Migraine (CM), or 15 or more migraine headaches per month, is common in tertiary headache care and is associated with a number of deleterious outcomes, especially higher disability and poorer quality of life, relative to…
- Trial name
- NCT01435941
- Testing
- Non-steroidal anti-inflammatory drug (NSAID), Triptan
- Volunteers
- 11,249 people
- Sponsor
- GlaxoSmithKline
Migraine Without Aura
Effect of PACAP38/VIP on Migraineurs Measured by Magnetic Resonance
The purpose of this study is to examine and compare the effect of pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) and vasoactive intestinal polypeptide (VIP) on intracranial arteries and neuronal activity in…
- Trial name
- NCT01471990
- Testing
- Pituitary Adenylate Cyclase-Activating Polypeptide-38, Vasoactive Intestinal Peptide
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Migraine
Topiramate, Amitriptyline Monotherapy and Combination Therapy in Migraine Prophylaxis
The goal of this clinical trial is to compare the efficacy and safety of Topiramate, Amitriptyline Monotherapy and Combination Therapy in Migraine Prophylaxis in outddor migraine patients attending headache clinic.
- Trial name
- NCT05759845
- Testing
- Topiramate 25Mg Tab, Amitriptyline 25 Mg Oral Tablet, topiramate 25mg plus amitriptyline 25mg
- Where
- Bangladesh
- Volunteers
- 150 people
- Sponsor
- Dr. Reaz Mahmud
Migraine Disorders
Temporal, Environmental, and Genetic Factors Regulating Exercise and Migraine
Chronic pain, of which migraine is among the most common, affects 100 million US adults and costs between $560 to $635 billion dollars annually.
- Trial name
- NCT04553445
- Testing
- Chronotype, Green exercise
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Migraine
Efficacy and Safety of Oral NBP Soft Capsules for the Prevention of Episode Migraine Attacks in Adult Migraine Patients
This is a multicentre, randomised, double-blind, placebo-controlled study to evaluate the efficacy, safety and tolerability of oral butylphthalide soft capsules for the prophylactic treatment of migraine in adults.
- Trial name
- ENERGY (NCT06968429)
- Testing
- NBP Softgel Capsules
- Volunteers
- 500 people
- Sponsor
- Chinese PLA General Hospital
Osteoarthritis, Migraine
Migraine and Neuropathic Pain in Osteoarthritis
The goal of this observational study is to estimate the frequency of neuropathic pain and migraines in a group of patients with osteoarthritis of the knees, hips, hands, spine or other joints.
- Conditions
- Osteoarthritis, Migraine, Neuropathic Pain
- Trial name
- MEDUSA (NCT06224959)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Clermont-Ferrand
Migraine
A Study of Lasmiditan (LY573144) in Children Aged 6 to 17 With Migraine
The purpose of the study is the measure the levels of lasmiditan in the body of children aged 6 to 17 with migraine. The study also will also examine the safety and tolerability of lasmiditan in children aged 6 to 17 with…
- Trial name
- NCT03988088
- Testing
- Lasmiditan
- Where
- 11 sites in United States, Japan and 1 more
- Volunteers
- 18 people
- Sponsor
- Eli Lilly and Company
Acute Treatment of Migraine
A Study to Find Out if the Medicine Called Rimegepant is Safe for Adults in India
This is a multicenter, single-arm, open-label Phase 4 study evaluating the safety and tolerability of rimegepant 75 mg orally disintegrating tablet (ODT) for the acute treatment of migraine (with or without aura) in adult…
- Trial name
- NCT07685769
- Testing
- Rimegepant 75 mg ODT
- Where
- 7 sites in India
- Volunteers
- 60 people
- Sponsor
- Pfizer
Migraine
Physiotherapy Intervention for Migraine Symptoms
The goal of this randomized control trial is to analyse the effectiveness of Physiotherapy intervention among university students with migraine symptoms. The main objective is: 1.
- Trial name
- NCT05741775
- Testing
- Aerobic training, Biofeedback Training
- Where
- Malaysia
- Volunteers
- 87 people
- Sponsor
- Universiti Tunku Abdul Rahman
Migraine Disorders, Vertigo
Videonystagmography and Vestibular Migraine
In the study, the investigators would like to examine whether there is a difference between patients with vestibular migraine, patients with episodic or chronic migraine and healthy subjects in the examination of…
- Trial name
- NCT07000929
- Testing
- Videonystagmography
- Where
- Germany
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Dr. med. Lukas Becker
Patent Foramen Ovale
Internal Microstructure of Patent Foramen Ovale Related to Stroke
This study aims to (1) investigate the internal microstructure of patent foramen ovale related to cryptogenic stroke, transient ischemic attack or migraine and determine the effectiveness of transcatheter closure in these…
- Trial name
- IMPORT (NCT04686253)
- Testing
- not appliable
- Where
- 2 sites in China
- Volunteers
- 1,200 people
- Sponsor
- China National Center for Cardiovascular Diseases
Migraine, Acute
Use Of SB-705498 In The Acute Treatment Of Migraine
Despite the success of the triptan class of drugs, approximately 60% of patients who take medication at the moderate to severe pain stage of acute migraine, still have pain of mild or greater degree at 2 hrs post dose.
- Trial name
- NCT00269022
- Testing
- SB-705498
- Where
- 4 sites in Australia, Canada and 2 more
- Volunteers
- 70 people
- Sponsor
- GlaxoSmithKline
Migraine Disorders, Migraine
Prevention Study in Adult Patients Suffering From Migraine Headaches
Purpose of the study is to evaluate dose response relationship, efficacy, safety and tolerability of target doses of GSK1838262 compared to placebo in the prophylactic treatment of migraine headache.
- Trial name
- NCT00742209
- Testing
- GSK1838262
- Where
- 59 sites in United States, Canada
- Volunteers
- 526 people
- Sponsor
- XenoPort, Inc.
Headache, Migraine
Headache Inducing Effect of Levcromakalim in Migraine With Aura Patients
To investigate the role of KATP channels in migraine with aura patients.
- Conditions
- Headache, Migraine, Aura
- Trial name
- NCT04012047
- Testing
- Levcromakalim, Saline
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- Danish Headache Center
Migraine, Healthy Participants
Investigation of Imagery Abilities in Individuals With Migraine
The aim of this study is to compare the motor imagery abilities of patients with migraine to those of healthy individuals, and to examine the relationship between motor imagery and proprioception (cervical and trunk), balance…
- Trial name
- NCT07546201
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Migraine
Acetaminophen and Ibuprofen With and Without Magnesium and Primary Migraine in Childhood
Aim: The purpose of this study was to evaluate both the effects of ibuprofen and/or acetaminophen for the acute treatment of primary migraine in children in or out prophylactic treatment with magnesium.
- Trial name
- NCT01756209
- Testing
- Magnesium 400Mg, Ibuprofen 10 mg/kg, acetaminophen 15 mg/kg
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- University of Catanzaro
Migraine Without Aura, Migraine With Aura
Candesartan Versus Propranolol for Migraine Prevention
The main aim of the present study is to compare candesartan with propranolol for migraine prophylaxis.
- Conditions
- Migraine Without Aura, Migraine With Aura, Chronic Migraine
- Trial name
- NCT00884663
- Testing
- Candesartan, propranolol
- Where
- Norway
- Volunteers
- 72 people
- Sponsor
- Norwegian University of Science and Technology
Migraine
A Safety Study of Galcanezumab in Participants With Migraine, With or Without Aura
The main purpose of this study is to evaluate the longer term safety of the study drug known as galcanezumab in participants with episodic or chronic migraine.
- Trial name
- NCT02614287
- Testing
- Galcanezumab
- Where
- 27 sites in United States, Belgium and 4 more
- Volunteers
- 270 people
- Sponsor
- Eli Lilly and Company
Migraine
Study on the Pharmacokinetics (PK) of DFN-15 vs Comparator and Food-effect on DFN-15 PK in Healthy Adult Subjects
An Open-Label, Three-Way Randomized, Single Dose Crossover Study Comparing Bioavailability of DFN-15 under fasting conditions versus Comparator under fed conditions and to determine food-effect of DFN-15 in Healthy Adult Subjects
- Trial name
- NCT03282838
- Testing
- DFN-15 (fasted), DFN-15 (fed), Comparator Celebrex® (fed)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Migraine Disorders, Headache, Migraine
Migraine Difficult to Treat: the Importance of Psychological Care in the Chronic Patient
In the study of migraine headaches, it is important to consider the affectation presented by those patients whose migraines do not respond easily to treatment.
- Trial name
- MIDITRA (NCT05658185)
- Testing
- MIDITRA
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- University of Valencia
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