Clinical trials: Headache (Migraine)
Migraine Headache
Effectiveness and Acceptability of MINDFULNESS by Smartphone, for Patients with Chronic Migraine and Medication Overuse
Chronic Migraine is a disabling condition that affects the 2% of migraine population. It is often associated with medication overuse that makes this condition very difficult to treat.
- Trial name
- ChroMig-Smart (NCT04389372)
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Migraine, Reflexology
The Effect of Foot Reflexology in Women With Migraine
This prospective randomized controlled study aims to investigate the effects of foot massage on pain, anxiety, kinesiophobia, and postural control in women aged 18-45 years diagnosed with migraine who attend the Neurology…
- Conditions
- Migraine, Reflexology, Pain, Anxiety
- Trial name
- NCT07651839
- Testing
- foot reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Migraine
Safety and Tolerability of Frovatriptan to Prevention of Menstrually Associated Migraine (MAM) Headaches
In this open-label, multi-center study, patients were treated with frovatriptan for a maximum of 12 perimenstrual periods (PMPs).
- Trial name
- MAM (NCT01035983)
- Testing
- Frovatriptan 2.5 mg
- Where
- 5 sites in Germany, Hungary and 3 more
- Volunteers
- 550 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Acute Treatment of Migraine
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of migraine in children and adolescents (≥ 6 to < 18 years of age).
- Trial name
- NCT04743141
- Testing
- Rimegepant (PF-07899801)
- Where
- 124 sites in United States, Poland and 1 more
- Volunteers
- 600 people
- Sponsor
- Pfizer
Migraine
Comparison of Neuromodulatory Treatment of Migraine Headache with Acupuncture and Transcranial Direct Current Stimulation
The goal of this clinical trial is to compare effects of the treatment with acupuncture and transcranial direct current stimulation (tDCS) in patients with migraine headache.
- Trial name
- NCT06834022
- Testing
- Transcranial direct current stimulation, Acupuncture
- Where
- Slovenia
- Volunteers
- 120 people
- Sponsor
- University Medical Centre Ljubljana
Migraine, Migraine With Aura
Oxygenation and Perfusion in Patients With Acute Migraine Attacks
The aim of the study is to retrospectively evaluate brain perfusion and oxygenation in acute migraine attacks. Magnetic resonance perfusion and susceptibility weighted imaging are the technics to measure perfusion and oxygenation…
- Conditions
- Migraine, Migraine With Aura, Migraine; Status
- Trial name
- OPAMA (NCT03536936)
- Volunteers
- 1,000 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Migraine
Comparison of Wet Cupping and Acupuncture in Migraine
The aim of this study is to evaluate the effects of wet cupping therapy (WCT) on migraine patients and compare it with acupuncture. The patients will be randomized into three groups.
- Trial name
- NCT05282134
- Testing
- Wet cupping therapy, Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Karabuk University
Migraine Disorders, Medication Overuse Headache
tDCS in Chronic Migraine With Medication Overuse (Edisom)
Transcranial direct current stimulation (tDCS) was suggested to provide beneficial effects in chronic migraine (CM), a condition often associated with medication overuse (MO) for which no long-term therapy is available.
- Trial name
- Edisom (NCT04228809)
- Testing
- tDCS
- Volunteers
- 135 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Migraine
An Efficacy and Tolerability Study of Topiramate in Participants With Migraine
The purpose of this study is to investigate the adequacy (reasonably good) of topiramate therapy (medicine or medical care given to a participant for a disease or condition) in prevention of migraine (type of severe headache that…
- Trial name
- NCT01060111
- Testing
- Topiramate Standard, Topiramate Slow, Propranolol booster
- Where
- 6 sites in South Korea
- Volunteers
- 250 people
- Sponsor
- Janssen Korea, Ltd., Korea
Migraine
Long-Term Extension Study With Eptinezumab as Preventive Treatment in Participants With Migraine in Japan
This study is an open label extension study, which means that the participants from the Lead-in Study 19140A (NCT04921384) can join this study, if they meet the study Eligibility Criteria, and continue to receive the study drug…
- Trial name
- NCT05064371
- Testing
- Eptinezumab
- Where
- 17 sites in Japan
- Volunteers
- 160 people
- Sponsor
- H. Lundbeck A/S
Migraine, Tension-Type Headache
An Evaluation of Brief Online Hypnosis for Migraine and Tension-type Headaches
This study aims to conduct an initial evaluation of whether a single, online, group-based session of hypnosis followed by self-hypnosis can decrease symptoms of migraine and tension-type headaches as well as improve quality of…
- Trial name
- NCT04523311
- Testing
- Hypnosis., Usual care
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Canterbury Christ Church University
Migraine
Migraine Research with Smartwatch Application
This clinical, prospective study aims to evaluate the effectiveness of wearable technology in capturing real-time data to assess disease activity in patients with episodic or chronic migraine undergoing different therapy…
- Trial name
- MIRA (NCT06862544)
- Testing
- Smartwatch (Withings Scanwatch 2)
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Migraine
Observational Study to Assess Migraine Prediction Tool
This is a prospective, observational study. The participant will be required to approve his/her participation in the study by completing the electronic consent form.
- Trial name
- NCT05523310
- Testing
- Daily questionnaire
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Theranica
Migraine
Candesartan for Migraine Prevention:
The main objective of this study is to see whether the favorable preventative effect of candesartan 16 mg per day in episodic migraine, that was found previously in two smaller randomized controlled cross-over studies, can be…
- Trial name
- CandMig-3 (NCT04574713)
- Testing
- Candesartan Oral Tablet 8 mg, Candesartan Oral Tablet 16 mg
- Where
- 10 sites in Estonia, Norway
- Volunteers
- 450 people
- Sponsor
- St. Olavs Hospital
Migraine
Prevalence of Phonophobia and Cutaneous Allodynia in Episodic Migraineurs
Cutaneous allodynia is an increased skin sensitivity experienced during a headache. It has been noted in several studies that in patients with migraine, seventy nine percent of the patients experienced allodynia on the facial…
- Trial name
- NCT00386880
- Testing
- Sounds
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Thomas Jefferson University
Photophobia, Traumatic Brain Injury
Objectively Diagnose and Monitor Treatment of Light Sensitivity
The purpose of this project is to provide a new framework for diagnosing and monitoring treatment of light sensitivity and headache by objective measurement of facial features, pupil responses, retinal electrical responses and…
- Conditions
- Photophobia, Traumatic Brain Injury, Migraine
- Trial name
- NCT03694626
- Testing
- Pupillography, Ocular Coherence Tomography (OCT), Wrist-watch sensor device
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Manual Lymphatic Drainage
Manual Lymph Drainage in Individuals With Migraine
In the literature, research into the examination of the effect of MLD on migraine is quite limited. Our study aimed to examine the effectiveness of manual lymph drainage and connective tissue massage treatments on neck pain and…
- Trial name
- NCT05976399
- Testing
- Connective Tissue Massage, Manual Lymph Drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Democracy University
Migraine
Healthcare Costs and Resource Utilization in Aimovig Migraine Patients: a Retrospective Study Using United States Claims Data
The proposed study is a retrospective, non-interventional analysis that uses medical and pharmacy claims data in the US from Komodo Health
- Trial name
- NCT05177406
- Testing
- Aimovig
- Where
- United States
- Volunteers
- 1,839 people
- Sponsor
- Novartis Pharmaceuticals
Migraine
Study to Test a Marketed Product in the Treatment of Migraine-associated Nausea
Study to test the effectiveness of a marketed drug in the treatment of migraine-associated nausea.
- Trial name
- NCT00250458
- Testing
- Comparator: Rizatriptan
- Volunteers
- 346 people
- Sponsor
- Organon and Co
Migraine Headache
Efficacy, Tolerability, and Safety Study of DFN-15
Efficacy, Tolerability, and Safety of DFN-15 in episodic migraine with or without aura, being conducted at multiple centers in the United States.
- Trial name
- NCT03006276
- Testing
- DFN-15 Active
- Where
- 45 sites in United States
- Volunteers
- 622 people
- Sponsor
- BioDelivery Sciences International
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