Clinical trials: Headache (Migraine)
Migraine
Study to Determine Safety and Efficacy of B244 in Subjects With Episodic Migraine
This is a prospective, randomized, vehicle-controlled, double-blind, multi-center study assessing the safety, tolerability, and efficacy of B244 delivered as an intranasal spray for preventive treatment in subjects with episodic…
- Trial name
- NCT03488563
- Testing
- B244, Vehicle
- Where
- 22 sites in United States
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- AOBiome LLC
Migraine, Headache, Tension-Type
Integrative and Complementary Therapy for Episodic Migraine and Tension-type Headache
This study is a monocentric uncontrolled observational study to evaluate a 12-14 day inpatient stay in an internal medicine clinic for integrative and complementary medicine for patients with episodic migraine and/or episodic…
- Trial name
- NAMIKOS (NCT06764914)
- Testing
- integrative and complementary medicine
- Volunteers
- 130 people
- Sponsor
- Kliniken Essen-Mitte
Familial Hemiplegic Migraine, Migraine With Aura
Calcitonin Gene-related Peptide in Familial Hemiplegic Migraine (FHM) and Migraine With Aura (MA)
The aim of the present study is to explore the importance of migraine phenotype on the headache/migraine responses after CGRP in FHM-patients, MA-patients and healthy volunteers.
- Conditions
- Familial Hemiplegic Migraine, Migraine With Aura, Healthy
- Trial name
- CGRP-2008 (NCT00687947)
- Testing
- CGRP
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine
Short-Term Effects of Acupuncture on Balance, and Quality of Life in Women With Migraine: A Pilot Study
The goal of this clinical trial is to learn about the short-term effects of acupuncture on migraine-related pain, postural balance, and quality of life in women with migraine.
- Trial name
- SAMBA (NCT07145242)
- Testing
- Acupuncture
- Where
- Lithuania
- Volunteers
- 12 people
- Sponsor
- Laura Zaliene
Migraine, Headache
Narrow Band Green Light and Migraine
Study volunteers are asked to use the Allay Lamp routinely during the 6-week study period. A web based survey is provided when the Lamp is purchased for study volunteers to complete.
- Trial name
- NCT04841083
- Testing
- Allay Lamp
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Vedanta Research
Migraine
A Research Study To Compare Two Kinds Of Daily Headache
Chronic daily headache has been classified into several categories. One category is of sudden onset and is called New Daily Persistent Headache (NDPH).
- Trial name
- NCT00335803
- Where
- United States
- Sponsor
- Thomas Jefferson University
Headache, Headache Disorders
Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire
The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Disability Questionnaire (HDQ).
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Headache, Tension
- Trial name
- NCT04736654
- Testing
- Survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Gazi University
Migraine
Corticosteroids for Acute Migraine in the Emergency Department
This is an emergency department based randomized trial in which we compare two different treatment for migraine headache. The goal is to decrease the number of headache days during the week after ED discharge.
- Trial name
- NCT02847494
- Testing
- metoclopramide, Dexamethasone, methylprednisolone acetate
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Montefiore Medical Center
Migraine, Acute Treatment of Migraine
Nerivio Efficacy by Time of Treatment Onset
This is a Post-marketing study investigating the impact of treatment time onset with Nerivio on the efficacy of Remote Electrical Neuromodulation (REN) for the acute treatment of migraine.
- Trial name
- NCT06976723
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 55,261 people
- Sponsor
- Theranica
Migraines
A Study of LY2951742 in Healthy Volunteers
To evaluate the safety and tolerability of LY2951742 given as single or multiple subcutaneous injection in healthy male subjects
- Trial name
- NCT01337596
- Testing
- LY2951742
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Chronic Migraine Headache, Chronic Tension-type Headache
Repeated Bilateral Greater Occipital Nerve Blockade in Chronic Migraine and Chronic Tension-Type Headache
This multicenter, randomized, double-blind, placebo-controlled clinical trial aims to evaluate the efficacy of repeated bilateral greater occipital nerve (GON) blockade in patients with chronic migraine and chronic tension-type…
- Trial name
- GONBLOCK-RCT (NCT07497646)
- Testing
- Bupivacaine, Normal Saline (0.9% NaCl), Greater occipital nerve blockade
- Where
- Turkey (Türkiye)
- Volunteers
- 290 people
- Sponsor
- Saglik Bilimleri Universitesi
Migraine Disorders
Treatment of Episodic Migraine With AURICular Neuromodulation
Migraine is a ubiquitous pathology affecting approximately 1 billion individuals and being the leading cause of morbidity worldwide before the age of 50.
- Trial name
- MENAURIC (NCT06623188)
- Testing
- Auricular neuromodulation
- Where
- 3 sites in France
- Volunteers
- 106 people
- Sponsor
- Hôpital Européen Marseille
Migraine, Headache
Magnesium Versus Prochlorperazine Versus Metoclopramide for Migraines
This investigation describes a proposed clinical trial that will evaluate the relative efficacy of intravenous magnesium sulfate for the treatment of migraine compared to intravenous metoclopramide (Reglan) and intravenous…
- Trial name
- MAGraine (NCT05967442)
- Testing
- Magnesium Sulfate, Metoclopramide 10mg, Prochlorperazine (Compazine) Injection
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Migraine Disorders
Closed-loop RTMS for Short-term Migraine Prevention
Migraine is a prevalent and debilitating primary headache disorder, where patients suffer from disabling symptoms that usually consist of a moderate to severe headache lasting 4 to 72 hours, nausea and/or vomiting, phonophobia…
- Trial name
- NCT06735768
- Testing
- rTMS treatment, Determination of motor hotspot and motor treshold
- Where
- Austria
- Volunteers
- 88 people
- Sponsor
- Brightmind.AI
Migraine Aura, Migraine With Aura
Induction of Migraine Attacks With Aura Using Calcitonin Gene-Related Peptide
Calcitonin gene-related peptide (CGRP) is a key neuropeptide in migraine pathophysiology and treatment. This study investigates whether CGRP administration can trigger aura in individuals with a diagnosis of migraine with aura.
- Trial name
- NCT07021859
- Testing
- Calcitonin-gene related peptide (CGRP)
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Stroke, Guillain-Barre Syndrome
Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology
This study examines the use of an AI-powered virtual assistant for quickly identifying and handling neurological emergencies, particularly in places with limited medical resources.
- Conditions
- Stroke, Guillain-Barre Syndrome, Facial Palsy, Migraine
- Trial name
- AIDEN (NCT06334796)
- Testing
- Virtual Assistant
- Where
- Argentina
- Volunteers
- 10 people
- Sponsor
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
Migraine, Migraine With or Without Aura
Evaluation of a Wearable Device for Acute Treatment of Migraines
The goal of this clinical trial is to determine the efficacy of a new, improved neuromodulation device that can be worn on the head and neck to relieve migraine pain.
- Conditions
- Migraine, Migraine With or Without Aura, Migraine, Acute, Migraine Headache
- Trial name
- NCT07015125
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Hinge Health, Inc
Headache, Migraine
Ubrogepant treatmeNt in mIgraine Patients Utilizing mOnoclonal aNtibodies
This is a prospective open-label randomized study assessing similar endpoints included in the pivotal trial for ubrogepant, which are pain freedom and freedom from the most bothersome symptom at two hours.
- Trial name
- UNION (NCT05503082)
- Testing
- Ubrogepant 50 MG [Ubrelvy], Ubrogepant 100 MG [Ubrelvy]
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- Chicago Headache Center & Research Institute
Chronic Migraine, Headache
Developing a Mobile Health Pain-Coping Skills Training Program for the Treatment of Chronic Migraine: AIM 4
This ClinicalTrials.gov record pertains only to the clinical trial described below in Aim 4. Aims 1-3 and 5 are described here as background information.
- Trial name
- NCT03465826
- Testing
- PainCOACH Pain Coping Skills Training, Treatment as Usual
- Sponsor
- Wake Forest University Health Sciences
Migraine, Healthy
Molecular and Functional PET-fMRI Measures of Analgesia in Migraine
The placebo effect is a phenomenon that has experienced major advances of its understanding in the last decade. However, mechanisms of placebo analgesia in chronic pain patients have yet to be compared to healthy subjects.
- Trial name
- NCT01970943
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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