Clinical trials: Headache (Migraine)
COVID-19
COVID-19 Pandemic and Migraine Disorder, Tension Headache and Epilepsy
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already rapidly spread around the world as a pandemic after its first report in Wuhan, China on December 12th 2019 …
- Trial name
- NCT05205590
- Testing
- Non
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Aswan University
Migraine
Study of Key Electro-acupuncture Technique on Migraine
A random controlled trail to evaluate the efficacy of migraine standard electroacupuncture formula, and to analysis the regulation of the intensity-effects and to observe the peripheral NO, CGRP and NF-кB expression level of…
- Trial name
- NCT02580968
- Testing
- electro-acupuncture, flunarizine hydrochloride
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Headache Disorders, Primary
Pediatric Headche Assessment Using HIT 6
The study is a prospective cohort study. The study population will include 100 children aged 6-18 years suffering from headaches who visited the Pediatric Neurology Clinic at Bnai Zion Medical Center and completed both the…
- Trial name
- NCT06598813
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Migraine, Headache
miR-155 Expression in Episodic and Chronic Migraine
Migraine is a common, yet often disabling, neurological disease that affects over 1 billion people around the world. It's the second most disabling disease globally and the leading cause of disability for people under the age of…
- Conditions
- Migraine, Headache, Pain, Chronic Migraine
- Trial name
- NCT05891808
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Migraine With Aura
PArtial REbreathing for Migraine With Aura 1
A prospective, multi-centre, randomized, double-blind, sham-controlled, parallel-group, group-sequential study to investigate safety and effectiveness of the Rehaler partial rebreathing device, in adults suffering from migraine…
- Trial name
- PAREMA1 (NCT05546385)
- Testing
- Partial Rebreathing Device
- Where
- 15 sites in United States, Germany
- Volunteers
- 142 people
- Sponsor
- Rehaler
Migraine
Candesartan for Migraine Prevention:
The main objective of this study is to see whether the favorable preventative effect of candesartan 16 mg per day in episodic migraine, that was found previously in two smaller randomized controlled cross-over studies, can be…
- Trial name
- CandMig-3 (NCT04574713)
- Testing
- Candesartan Oral Tablet 8 mg, Candesartan Oral Tablet 16 mg
- Where
- 10 sites in Estonia, Norway
- Volunteers
- 450 people
- Sponsor
- St. Olavs Hospital
Chronic Migraine
Double-blind Randomized Clinical Trial of Transcranial Magnetic Stimulation in Chronic Migraine
The purpose of this study is to determine whether active repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex is safe and effective for preventive treatment of chronic migraine, compared to…
- Trial name
- TMS-CHROMIG (NCT01496950)
- Testing
- 10Hz active rTMS
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Hospital Israelita Albert Einstein
Hypertension, Heart Failure
LSFG-SKIN, Laser Speckle Flowgraphy
The purpose of this project is to quantify normal and abnormal skin blood flow regionally in different areas of the body(face, extremities, over burns and wounds) at baseline and over time in response to treatment or…
- Conditions
- Hypertension, Heart Failure, Vascular Ischemia, Burns
- Trial name
- NCT03660618
- Testing
- laser speckle flowgraphy
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Migraine, Tension Type Headache
The Efficacy of a Cognitive and Physical Intervention to Reduce Head and Muscle Pain in a Working Community
This study is a controlled, cluster randomised, interventional trial to evaluate the effectiveness of a workplace cognitive and physical program (Intervention), in reducing the frequency of head and neck pain in an extensive…
- Conditions
- Migraine, Tension Type Headache, Cervical Pain
- Trial name
- NCT00551980
- Testing
- Cognitive, Relaxation, Exercise Therapy
- Where
- Italy
- Volunteers
- 2,895 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Migraine
Migraine in Poland - a Web-based Cross-sectional Survey
A survey of Polish respondents will aim to define migraine characteristics in Polish subjects. To achieve this, a structured questionnaire based mainly on American Migraine Prevalence and Prevention Study has been prepared to…
- Trial name
- MIGinPOL2021 (NCT05087420)
- Where
- 2 sites in Poland
- Volunteers
- 2,800 people
- Sponsor
- Swiat Zdrowia
Migraine
A Research Study To Evaluate If Frovatriptan Is Safe And Effective In Preventing Migraine Headache After Fasting
We are testing the hypothesis that subjects in the treatment group will experience fewer fasting induced headaches as compared to those in the placebo group.In our clinical experience, we estimate that approximately 25% of our…
- Trial name
- NCT00440232
- Testing
- Frovatriptan
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Thomas Jefferson University
Migraine, Cluster Headache
Intranasal Cooling for Cluster Headache and Migraine
This study will be looking at the clinical efficacy of using a intranasal evaporative cooling device in providing relief of the symptoms of migraine and cluster headache.
- Trial name
- COOLHEAD (NCT01898455)
- Testing
- RhinoChill intranasal cooling
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Cumbria Partnership NHS Foundation Trust
Migraine
Ginger Capsules for the Prophylactic Treatment of Migraine
The main objective of the study is to evaluate ginger efficacy as an prophylactic treatment of migraine.
- Trial name
- NCT02570633
- Testing
- Extract of ginger, Cellulose
- Where
- Brazil
- Volunteers
- 107 people
- Sponsor
- Federal University of Minas Gerais
Inflammation, Migraine
Inflammatory Markers Identification in Migraine Patients
Migraine is prevalent in 10-12% of the population. It involves the development of a cranial perivascular neurogenic inflammation. Recent information suggests that migraine might be a risk factor to stroke.
- Conditions
- Inflammation, Migraine, Headache
- Trial name
- NCT01618201
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Migraine
Psychological and Biological Markers of Refractory Migraine
The term "refractory" migraine describes a particularly aggressive form of the disease in which the patient does not benefit from any of the preventive therapies with the various classes of drugs available, including treatment…
- Trial name
- NCT05046119
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Migraine Disorders, Migraine Without Aura
1H Magnetic Resonance Spectroscopy in Migraine Patients
To investigate the glutaminergic system in the onset of migraine-like attacks.
- Conditions
- Migraine Disorders, Migraine Without Aura, Headache Disorders, Primary, Headache Disorders
- Trial name
- NCT04220606
- Testing
- Glyceryl trinitrate (I.V. infusion 0.5 µg/kg/min over 20 min)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Migraine
Maximizing Outcomes in Treating Acute Migraine
AXS-07 is an oral, investigational medicine consisting of MoSEIC meloxicam and rizatriptan, which is being developed for the acute treatment of migraine with or without aura in adults.
- Trial name
- MOMENTUM (NCT03896009)
- Testing
- AXS-07 (MoSEIC meloxicam and rizatriptan), Meloxicam, Rizatriptan
- Where
- 85 sites in United States
- Volunteers
- 1,594 people
- Sponsor
- Axsome Therapeutics, Inc.
Pregnancy, Migraine
External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy
This online registry aims to understand the potential benefits and safety of external trigeminal nerve stimulation for the treatment of migraine in pregnant women.
- Conditions
- Pregnancy, Migraine, Headache, Postpartum
- Trial name
- NCT06788977
- Testing
- external Trigeminal Nerve Stimulation
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Cefaly Technology
Migraine, Acute Treatment of Migraine
Dose Ranging Study of Rimegepant (BMS-927711) for the Acute Treatment of Migraine
The primary purpose of this study is to evaluate the efficacy of rimegepant (BMS-927711) compared with placebo in the acute treatment of migraine as measured by Pain Freedom (headache pain intensity level reported as "no pain")…
- Trial name
- NCT01430442
- Testing
- Rimegepant, Sumatriptan
- Where
- 41 sites in United States
- Volunteers
- 1,026 people
- Sponsor
- Pfizer
Migraine
Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications
Zavegepant (Zavzpret) is approved for the acute treatment of migraine with or without aura in the US. The purpose of this study is to investigate the effectiveness and tolerability of zavegepant for the acute treatment of…
- Trial name
- NCT06401642
- Testing
- Zavegepant
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
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