Clinical trials: Headache (Migraine)
Migraine Disorders
Relative Bioavailability of a Single Dose of BI 44370 Tablet During and Between Migraine Attacks
The general aim is to evaluate the relative oral bioavailability of BI 44370 TA tablets during and between migraine attacks as well as Safety, Tolerability and Pharmacokinetic
- Trial name
- NCT00743015
- Testing
- BI 44370 TA tablet
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 19 people
- Sponsor
- Boehringer Ingelheim
Migraine, Aura
MIST II PFO-Migraine Trial With BioSTAR® Bioabsorbable Septal Repair Implant
The objective of the study is to investigate the safety and effectiveness of PFO closure with the BioSTAR Septal Repair Implant System in a population of patients that have refractory migraine (with aura) and who have failed…
- Conditions
- Migraine, Aura, Patent Foramen Ovale
- Trial name
- NCT00283738
- Testing
- BioSTAR Septal Repair Implant System
- Where
- 2 sites in United States
- Volunteers
- 610 people
- Sponsor
- NMT Medical
Nummular Headache, Migraine
Observational Prospective Study on the Presence of Typical Migraine Features in Nummular Headache Patients: The Numamig Study
Observational analytic study with prospective cohort design that aim to describe the presence of typical features of migraine in a cohort of nummular headache patients.
- Conditions
- Nummular Headache, Migraine, Headache Disorders, Primary
- Trial name
- NCT04299958
- Testing
- Patient diary
- Where
- Spain
- Volunteers
- 19 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Headache
Neuromodulation Treatment of Vestibular Migraines
This is a non-randomized pilot study to test the efficacy of neuromodulation via caloric stimulation on vestibular migraines. All subject who meet the study criteria will be in an active treatment group.
- Trial name
- NCT02866084
- Testing
- Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Migraine
Intravenous Metoclopramide Versus Dexketoprofen Trometamol Versus Metoclopramide+ Dexketoprofen Trometamol in Migraine
Acute headache is one of the most common reasons for presentation to the emergency department (ED), accounting for 2-3% of all emergency visits.
- Trial name
- NCT04252521
- Testing
- metoclopramide, dexketoprofen trometamol, metoclopramide+dexketoprofen trometamol
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Adiyaman University Research Hospital
Migraine, Headache
Amitriptyline vs GON and SON Blocks in Migraine
Comparison of efficacy and safety of amitriptyline and nerve blocks
- Trial name
- NCT04750967
- Testing
- Lidocaine 1% Injectable Solution, Amitriptyline
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Migraine Disorders, Post-Traumatic Headache
The Role of Osteopathic Manipulation in the the Management of Post-traumatic Migraine
This study evaluates the use of osteopathic manipulation (manual medicine) for migraine headache following traumatic head injury.
- Trial name
- OMT/mTBI (NCT03588364)
- Testing
- Osteopathic Manipulation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, San Diego
Migraine With Aura
Induction of Migraine Aura With Sildenafil
In a double blind placebo-controlled cross-over study the effect of Sildenafil on aura and migraine headache induction is tested in patient with migraine with aura.
- Trial name
- NCT02795351
- Testing
- Sildenafil
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Herlev Hospital
Migraine Disorders
Study to Evaluate the Efficacy and Safety of Oral Sumatriptan for the Acute Treatment of Migraine in Children and Adolescents
The purpose of this study is to evaluate the efficacy and safety of a range of doses of oral sumatriptan for the acute treatment of migraine in children ages 10 to 17.
- Trial name
- NCT00963937
- Testing
- Sumatriptan 25 mg, Sumatriptan 50 mg
- Where
- 16 sites in Japan
- Volunteers
- 178 people
- Sponsor
- GlaxoSmithKline
HEADACHE
Efficacy Evaluation Of Great Occipital Nerve Electrical Stimulation On Rebound Headache
SENGO-CAM study is a sham-controlled simple blind trial which aim is to study the efficacy of great occipital nerve stimulation (GONS) associated with medication withdrawal in the treatment of medication overuse headache…
- Trial name
- NCT01184222
- Testing
- great occipital nerve stimulation
- Where
- 4 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Chronic Migraine Headache
CHROnic Migraine Embolization
To evaluate the effectiveness and safety of middle meningeal artery (MMA) embolization using non-adhesive materials SQUID 12 and SQUID 18 as a treatment method for patients with chronic resistant migraine.
- Trial name
- CHROME (NCT06848166)
- Testing
- liquid embolic agent SQUID 12, liquid embolic agent SQUID 18
- Where
- Kyrgyzstan
- Volunteers
- 30 people
- Sponsor
- Vedanta University Clinic
Migraine With Aura
Study of NXN 188 for the Treatment of Migraine With Aura
NXN-188 Dihydrochloride is being developed as an immediate release oral product for the treatment of acute migraine. This study is being conducted to evaluate NXN-188 in subjects with a migraine history of aura.
- Trial name
- NCT00920686
- Testing
- NXN-188, sumatriptan succinate
- Where
- 16 sites in United States
- Volunteers
- 239 people
- Sponsor
- NeurAxon Inc.
Headache Disorders, Dizziness
Headache Ear Auditory Dizziness Sinus (HEADS) Registry
The Headache, Ear, Auditory, Dizziness, Sinus (HEADS) Registry is a study over time of individuals living in the United States who experience sinus, vestibular, auditory, and headache symptoms.
- Conditions
- Headache Disorders, Dizziness, Vestibular Diseases, Sinus Disease
- Trial name
- HEADS (NCT07754266)
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Association of Migraine Disorders
Epilepsy, Migraine
A Pilot Study of Creative Arts Interventions for Neurology Inpatients
The purpose of the study is to assess the feasibility of a Creative Artists Program intervention with epilepsy and headache patients admitted to Dartmouth-Hitchcock Medical Center for care by the Department of Neurology.
- Trial name
- NCT03520777
- Testing
- Art Intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Migraine, With or Without Aura
Trial in Adult Subjects With Acute Migraines
The purpose of this study is to compare the efficacy of BHV-3000 (rimegepant ODT) versus placebo in subjects with Acute Migraines.
- Trial name
- NCT03461757
- Testing
- Rimegepant
- Where
- 69 sites in United States
- Volunteers
- 1,811 people
- Sponsor
- Pfizer
Migraine
ARISE-A Chinese Real-world Study of Rimegepant for the Acute Treatment of Migraine
Research question and objectives Primary endpoint To evaluate the effectiveness of Rimegepant in the acute treatment of migraine as measured by most severe pain, onset of pain relief, satisfaction with pain relief, and…
- Trial name
- NCT06439628
- Testing
- Rimegepant
- Where
- 3 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Chinese PLA General Hospital
Migraine in Adolescence, Headache
A Wearable Nerve Stimulator for Chronic Migraine/Headache and Mood Disturbance in Adolescents
The aim of this clinical trial is to test a wrist-worn nerve stimulator in adolescents with chronic migraine/headache and mood disturbance.
- Conditions
- Migraine in Adolescence, Headache, Mood Disturbance
- Trial name
- NCT05702528
- Testing
- Apollo Neuro
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of South Carolina
Migraine
ADX10059 Migraine Prevention Study
Evaluation of ADX10059 to prevent migraine attacks
- Trial name
- NCT00820105
- Testing
- ADX10059
- Where
- 31 sites in Austria, Belgium and 3 more
- Volunteers
- 350 people
- Sponsor
- Addex Pharma S.A.
Posttraumatic Headache, Combat Disorders
Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin
The purpose of this study is to determine if prazosin is more effective than placebo in decreasing frequency, severity, disability, and other negative effects of headaches related to mild traumatic brain injury in Service Members…
- Conditions
- Posttraumatic Headache, Combat Disorders, Post Concussion Syndrome, Headache
- Trial name
- NCT02266329
- Testing
- prazosin hydrochloride
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- VA Office of Research and Development
Migraine
Bilateral DLPC tDCS in Drug-resistant Migraine
The goal of this clinical trial is to study and describe the effects of bilateral tDCS applied to dorso-lateral-prefrontal cortex (DLPC) in patients with drug-resistant migraine in terms of reduction in frequency of pain, impact…
- Trial name
- NCT06079801
- Testing
- Transcranial direct current stimulation (tDCS), anti-CGRP-mAbs
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Clínica de Intervención en Neurociencias
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