Clinical trials: Headache (Migraine)
Migraine Disorders, Headache Disorders
Idebenone for the Preventive Treatment of Migraine
Idebenone improves energy metabolism similarly to Coenzyme Q10, which is effective in migraine prophylaxis. The investigators compare idebenone (90 mg/day, 270 mg/day) and placebo in 180 migraine patients in a double-blind…
- Trial name
- NCT04151472
- Testing
- 90mg Idebenone, 270mg Idebenone
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Migraine, Headache
Ticagrelor Therapy for RefrACTORy Migraine Study
This is a prospective, open-label, single-arm pilot study treating 40 subjects to assess the hypothesis that P2Y, G protein-coupled 12 (P2Y12) inhibition with Brilinta/ticagrelor (90 mg by mouth (PO) twice a day) reduces episodic…
- Conditions
- Migraine, Headache, Migraine Headache
- Trial name
- TRACTOR (NCT02518464)
- Testing
- Ticagrelor 90 mg twice per day
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Epilepsy
Study on Migraine and Headache in Epileptic Patients
The purpose of this study is to collect data from patients who are diagnosed with epilepsy and are followed up in epilepsy clinics.
- Trial name
- NCT00642564
- Testing
- Observational study in Epileptic Patients
- Volunteers
- 955 people
- Sponsor
- Johnson & Johnson Taiwan Ltd
Migraine Disorders, Headache Disorders
Therapy for Migraine Prevention in Children 6-11 Years of Age
The aim of this study is to evaluate the effect of SPN-538 for the prophylaxis of migraine in pediatric patients 6 to 11 years old.
- Trial name
- NCT04050293
- Testing
- SPN-538
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Chronic Migraine Headache, Chronic Migraine, Headache
EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) OF PRIMARY MOTOR CORTEX ON HEADACHE FREQUENCY IN PATIENTS WITH CHRONIC MIGRAINE
Migraine is a common, heterogeneous neurological disorder affecting approximately 10-15% of the global population and is the third most prevalent disease worldwide.
- Trial name
- NCT07743814
- Testing
- Transcranial Direct Current stimulation
- Where
- India
- Volunteers
- 32 people
- Sponsor
- Dr. Ram Manohar Lohia Hospital
Migraine
The Evolution and Management of Migraine Recurrence Beyond 24 Hours
What is the course of migraine headache recurrence, how is it managed, what characteristics are associated with it, and how does it influence patient satisfaction with treatment?
- Trial name
- NCT00754611
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rowan University
Episodic Migraine
A Study Evaluating the Effectiveness of AMG 334 Injection in Preventing Migraines in Adults Having Failed Other Therapies
The purpose of this study is to determine if AMG 334 is effective in treating migraines in patients who have failed other preventive migraine treatments.
- Trial name
- NCT03096834
- Testing
- AMG334 (70 mg) Pre-Filled Syringe (PFS)
- Where
- 59 sites in Australia, Austria and 14 more
- Volunteers
- 246 people
- Sponsor
- Novartis Pharmaceuticals
Migraine Headache
Mesotherapy Versus Systemic Therapyin Treatment of Migraine Headache
Introduction:Migraine is a prevalent disabling primary headache disorder which is classified in two major types; migraine without aura and migraine with aura.
- Trial name
- NCT04519346
- Testing
- intradermal injection
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ataturk University
Migraine
Oral Dexamethasone for the Treatment of Acute Migraine Recurrence in the Pediatric Emergency Department
Migraine recurrence is common amongst pediatric patients being discharged from the emergency department after treatment for migraine.
- Trial name
- NCT02794441
- Testing
- Dexamethasone
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Children's Hospital of Eastern Ontario
Myofascial Trigger Points, Chronic Musculoskeletal Pain
Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Shoulder Osteoarthritis(OA)
Chronic musculoskeletal pain (CMP) is a common disease in China, with a high incidence among the elderly, and has a significant impact on patients' quality of life. Shoulder osteoarthritis is a common type of CMP.
- Conditions
- Myofascial Trigger Points, Chronic Musculoskeletal Pain, Shoulder Osteoarthritis
- Trial name
- NCT07347054
- Testing
- Joint Cavity Injection, MTrPs Injection
- Where
- China
- Volunteers
- 1,036 people
- Sponsor
- Beijing Tiantan Hospital
Migraine
A Double Blind Placebo-controlled, Parallel Group Study to Assess the Efficacy and Safety of Frovatriptan in the Acute Treatment of Migraine
The purpose of this study is: 1. To compare the efficacy of a single dose of Frovatriptan 2.5 mg with that of placebo in acute treatment of up to one migraine attract 2. To assess recurrence rate between two group 3.
- Trial name
- NCT00821483
- Testing
- Frovatriptan
- Volunteers
- 298 people
- Sponsor
- SK Chemicals Co., Ltd.
Migraine
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Migraine Headaches
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Trial name
- NCT04211454
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Migraine Headaches
To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migrane Headaches
to demonstrate the superiority of Trexima (combination of sumatriptan as the succinate 85 mg and naproxen sodium 500 mg) versus placebo in the acute treatment of migraine to demonstrate the superiority of Trexima versus the…
- Trial name
- NCT00434083
- Testing
- sumatriptan, naproxen sodium
- Where
- 2 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- POZEN
Chronic Migraine Headache, Chronic Tension-type Headache
Repeated Bilateral Greater Occipital Nerve Blockade in Chronic Migraine and Chronic Tension-Type Headache
This multicenter, randomized, double-blind, placebo-controlled clinical trial aims to evaluate the efficacy of repeated bilateral greater occipital nerve (GON) blockade in patients with chronic migraine and chronic tension-type…
- Trial name
- GONBLOCK-RCT (NCT07497646)
- Testing
- Bupivacaine, Normal Saline (0.9% NaCl), Greater occipital nerve blockade
- Where
- Turkey (Türkiye)
- Volunteers
- 290 people
- Sponsor
- Saglik Bilimleri Universitesi
Migraine, Headache
Magnesium Versus Prochlorperazine Versus Metoclopramide for Migraines
This investigation describes a proposed clinical trial that will evaluate the relative efficacy of intravenous magnesium sulfate for the treatment of migraine compared to intravenous metoclopramide (Reglan) and intravenous…
- Trial name
- MAGraine (NCT05967442)
- Testing
- Magnesium Sulfate, Metoclopramide 10mg, Prochlorperazine (Compazine) Injection
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Migraine, Migraine With Aura
A Study of a Melatonin Receptor Agonist to Prevent Migraine
The purpose of this study is to see if ramelteon will reduce the number of migraine headaches over a 12 week period. The safety and tolerability of ramelteon will also be evaluated. Ramelteon has been approved by the U.S.
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- NCT00739024
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Swedish Medical Center
Headache Disorders, Tension-Type Headache
An Open Internet-based Survey and Natural Language Processing Project Analysing Written Monologues by Headache Patients
Headache disorders are among the most prevalent medical conditions worldwide. The diagnosis of headache disorders is based on medical history taking.
- Conditions
- Headache Disorders, Tension-Type Headache, Migraine Disorders, Cluster Headache
- Trial name
- NLPH-OPEN (NCT05153876)
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 1,150 people
- Sponsor
- University Hospital, Ghent
Migraine Headache, Episodic
A Non-Invasive Neuromodulation Device for Treatment of Migraine Headache
This is a randomized, blinded study designed to assess the efficacy of a portable, non-invasive neuromodulation system for the treatment of episodic migraine headaches.
- Trial name
- NCT01899040
- Testing
- neuromodulation for episodic migraine headache
- Where
- 6 sites in United States, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Scion NeuroStim
Chronic Daily Headache
Intensive Meditation and Migraines: Effects on Health and Well Being
Participants completing training in intensive meditation and continuing frequent practice for one year would experience reduced frequency, duration and severity of headaches along with improved awareness of the triggers of their…
- Trial name
- NCT00663585
- Testing
- Vipassana Meditation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johns Hopkins University
Migraine Disorders, Headache Disorders
Topical Bimatoprost in the Treatment of Migraine
The study is to assess the effectiveness of topically applied bimatoprost in reducing migraine headache frequency, severity, and duration. It will also assess the effect of topical bimatoprost on quality of life.
- Trial name
- NCT03419715
- Testing
- Bimatoprost Topical Solution, Control
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Manistee Partners
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