Clinical trials: Headache (Migraine)
Migraine
A Controlled Trial of Erenumab in Migraine Prevention
The purpose of this study was to assess the efficacy and safety of erenumab for prevention of migraine in Japanese adults with episodic migraine (EM) and chronic migraine (CM).
- Trial name
- NCT03812224
- Testing
- Erenumab
- Where
- 41 sites in Japan
- Volunteers
- 261 people
- Sponsor
- Amgen
Migraine Disease
The Migraine and Pain Study GeneBank at Scripps Clinic Registry (MAPS)
The objective of this study is to obtain blood or saliva samples to define genes for migraine and pain diseases.
- Trial name
- MAPS (NCT01004835)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Scripps Translational Science Institute
Chronic Migraine, Adverse Childhood Experiences
Effects of Online Mindfulness Therapy on Pain and Stress in Adults With Chronic Migraine and Adverse Childhood Experiences
This study aims to evaluate the effectiveness of an online Mindfulness-Based Cognitive Therapy (MBCT) program in reducing pain, stress-related symptoms, and improving functionality in adults with chronic migraine and a history of…
- Conditions
- Chronic Migraine, Adverse Childhood Experiences, Depression, Anxiety
- Trial name
- NCT07033520
- Testing
- Online Mindfulness-Based Cognitive Therapy
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Fundación Cardiovascular de Colombia
Migraine
Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention
The primary objective of the study was to evaluate the effect of erenumab compared to placebo on the change from baseline in monthly migraine days.
- Trial name
- STRIVE (NCT02456740)
- Testing
- Erenumab
- Where
- 129 sites in United States, Austria and 11 more
- Volunteers
- 955 people
- Sponsor
- Amgen
Irritable Bowel Syndrome (IBS), Functional Abdominal Pain
Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
This protocol matches child subjects with peer mentors of similar age who have learned to function successfully with a chronic pain disorder.
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Abdominal Pain, Fibromyalgia, Complex Regional Pain Syndrome (CRPS)
- Trial name
- NCT01118988
- Testing
- Mentorship
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles
Migraine
Real-world Impact of Erenumab on Sick-leaves, Health Care Resource Use and Comorbidities.
This was a retrospective registry-based study utilizing data collected in association with clinical care of patients. All data was stored in electronic health records at Terveystalo data base, and no patients were contacted for…
- Trial name
- NCT05375097
- Testing
- Erenumab
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Novartis Pharmaceuticals
Migraine
Investigation of Efficacy and Outcome of a New Medical Device for Treatment of Migraine
The purpose of this study is to evaluate the efficacy of a novel therapy for treatment of migraine, pain reduction and relief of associated symptoms during ongoing migraine attacks, and presence of a preventive effect two months…
- Trial name
- NCT01488110
- Testing
- In-house prototype invented by Jan-Erik Juto
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska University Hospital
Migraine
Effect of Osteopathic Intervention on Migraine
Migraine is a common, disabling neurological condition characterized by severe, often unilateral pain accompanied by sensory symptoms like nausea and photophobia.
- Trial name
- NCT07542340
- Testing
- Osteopathic Intervention Protocol
- Volunteers
- 45 people
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Acute Migraine
Intravenous Dexketoprofen and Paracetamol in the Treatment of Headache Caused by Acute Migraine Attack
Patients with acute migraine attack make up the majority of patients consulting the emergency services due to headache. The aim of treatment in the emergency service is to achieve a minimum level of undesirable side effects and…
- Trial name
- NCT01730326
- Testing
- Paracetamol, Dexketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Pamukkale University
Migraine Headaches
The Utility of Telemedicine in the Management of Migraine
Patients will be randomly assigned to receive their follow-up care via telemedicine or in-office visits.
- Trial name
- NCT01706003
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Texas Southwestern Medical Center
Migraine
Mechanism-based Choice of Therapy for Pain: Can Successful Prevention of Migraine be Coupled to a Psychophysical Pain Modulation Profile?
Mechanism-based choice of therapy for pain: Can successful prevention of migraine be coupled to a psychophysical pain modulation profile?
- Trial name
- NCT01161017
- Testing
- Amitriptyline, Topiramate
- Where
- Israel
- Volunteers
- 67 people
- Sponsor
- Rambam Health Care Campus
Headache, Migraine, Headache
Evaluating the Effectiveness of a Headache Management Program in Primary Care Settings
Between January 2020 to August 2021, fifty percent of patients referred from Geisinger's primary care sites to Neurology for headaches did not trial appropriate first line therapy prior to referral, and there was limited access…
- Trial name
- NCT05067725
- Testing
- CarePath
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Geisinger Clinic
Migraine
Feasibility of Using a Mobile Device Controlled Micro-pressure Pulse Insufflator for Acute Migraine Relief
Evaluate the feasibility of using a mobile interface to control the insufflator device administering treatment for aborting (stopping) an acute episode of migraine.
- Trial name
- NCT03263897
- Testing
- insufflation
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Caps Research Network
Migraine Headaches, Breathing Techniques
Effect of Breathing Techniques on Migraine Attacks and Severity
Background: Migraine is a very common neurobiological disorder caused by increased excitability of the Central Nervous System. It is among the causes of the highest morbidity worldwide.
- Trial name
- NCT05536635
- Testing
- breathing techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Dokuz Eylul University
Migraine, Migraine Disorders
Assessment of Prolonged Safety and tOLerability of in Migraine Patients in a Long-term OpeN-label Study
This is a 128-week open-label study to assess the long-term safety and tolerabilty of the monoclonal antibody erenumab in migraine patients.
- Conditions
- Migraine, Migraine Disorders, Migraine Headache
- Trial name
- APOLLON (NCT04084314)
- Testing
- Erenumab
- Where
- 75 sites in Germany
- Volunteers
- 701 people
- Sponsor
- Novartis Pharmaceuticals
Migraine
The Effect of Nasal Carbon Dioxide in the Treatment of Moderate to Severe Migraine
This multi-center, double-blind, placebo-controlled, parallel group trial carbon dioxide in the treatment of moderate to severe migraine.
- Trial name
- NCT01253915
- Testing
- Nasal Carbon Dioxide
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Capnia, Inc.
Migraine With Aura
Neurogenetic And Hemodynamic Of Migraine Aura And Pfo
The PFOCUS Study aims to clarify the relationship between patent foramen ovale (PFO) and migraine with aura (MA). Patients diagnosed with MA according to ICHD-3 criteria will be classified as cases (PFO+) or controls (PFO-) based…
- Trial name
- PFOCUS (NCT07349004)
- Testing
- Intervention
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Azienda Usl di Bologna
Migraine
Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines
Migraines are a specific type of headache that frequently recur and are very painful. Although there are many medications that are effective against migraines, none of these medications cure 100% of migraines.
- Trial name
- NCT00122278
- Testing
- Dexamethasone
- Where
- 3 sites in United States
- Volunteers
- 205 people
- Sponsor
- Montefiore Medical Center
Primary Headache Disorders, Tension Headache
Pericranial and General Sensitivity in Patients With Primary Headache
Primary headaches such as migraine and tension type headache are among the most common neurological disorders and frequently cause significant disability and reduced quality of life.
- Conditions
- Primary Headache Disorders, Tension Headache, Tension-type Headache, Migraine
- Trial name
- HEAD-TMD (NCT07514208)
- Testing
- Pericranial Tenderness Assessment, Pressure Pain Threshold Assessment, Temporomandibular Disorder Assessment
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Migraine
Clinical Experience With Transcutaneous Supraorbital Nerve Stimulation in Refractory Migraine
Migraine is included in the top-ten disabling diseases and conditions among the Western populations. Non-invasive neurostimulation (t-SMS), including the Cefaly® device, for the treatment of various types of pain is a relatively…
- Trial name
- NCT03125525
- Testing
- Cefaly device
- Volunteers
- 37 people
- Sponsor
- Corfu Headache Clinic
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