Clinical trials: Headache (Migraine)
Cyclic Vomiting Syndrome, Abdominal Migraine
Auricular Neurostimulation for Cyclic Vomiting Syndrome
This study evaluates the efficacy of auricular neurostimulation via an non-invasive percutaneous electrical nerve field stimulator in children and adults with cyclic vomiting syndrome.
- Trial name
- NCT03434652
- Testing
- Percutaneous neurostimulation
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Medical College of Wisconsin
Headache
Oxygen Therapy for the Treatment of Undifferentiated Headache in the Emergency Department
This study will randomly assign emergency department patients seeking treatment for a headache to one of three groups. The first group will receive standard emergency care as determined by the treating physician, the second group…
- Trial name
- NCT00856232
- Testing
- Medical Air, Oxygen
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Fibromyalgia
Estrogen Receptor 1 Gene Polymorphism Frequency in Fibromyalgia Syndrome
Fibromyalgia Syndrome (FMS) is a chronic musculoskeletal disorder accompanied by diffuse body pain, increased fatigue and tenderness in specific anatomical regions, and sleep disturbance.
- Trial name
- NCT03786393
- Testing
- ACR 1990 fibromyalgia critters
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Acute Mountain Sickness
Calcitonin Gene-related Peptide Antibody in Acute Mountain Sickness
Acute mountain sickness (AMS) is a common condition that can occur when healthy people travel quickly to high altitude. Typical symptoms include headache, nausea, tiredness, dizziness, and poor sleep.
- Trial name
- NCT07653516
- Testing
- Fremanezumab 225 Mg/1.5 mL Subcutaneous Solution
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Migraine
Efficacy and Safety of Cyclobenzaprine Hydrochloride Extended Release for the Treatment of Chronic Migraine
The primary objective of the study is to evaluate the effectiveness and safety of cyclobenzaprine hydrochloride extended release (Amrix 15mg/day) for the prophylaxis of chronic migraine compared to a placebo medication.
- Trial name
- NCT01151787
- Testing
- cyclobenzaprine hydrochloride
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Kennedy Medical Group
Intervention
A Non-Invasive Neuromodulation Device for Prevention of Episodic Migraine Headache
This study will assess the efficacy of a neuromodulation device for the treatment of episodic migraine headache.
- Trial name
- NCT02991430
- Testing
- active neuromodulation for episodic migraine headache
- Where
- 10 sites in United States, United Kingdom
- Volunteers
- 45 people
- Sponsor
- Scion NeuroStim
Migraine
Study to Test an Approved Product in the Early Treatment of Migraine (0462-065)
The purpose of this study is to test the effectiveness of an approved drug in the early treatment of migraine while the pain is still mild.
- Trial name
- NCT00092963
- Testing
- MK0462, rizatriptan benzoate / Duration of Treatment: 1day
- Volunteers
- 529 people
- Sponsor
- Organon and Co
Migraine, Migraine in Adolescence
Headache Education and Awareness vs. Daily Mindfulness Strategies - Understanding Pain
The goal of this study (supported by and included in the NIH HEAL Initiative: https://heal.nih.gov/) is to learn if a fully virtual study comparing two telehealth group interventions for adolescents with migraine is feasible and…
- Trial name
- HEADS-UP (NCT07513662)
- Testing
- BREATHE with Headache (BREATHE-HA), Enhanced Standard-of-Care: Headache Education
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Colorado, Denver
Migraine
A Study of Lasmiditan (LY573144) in Children Aged 6 to 17 With Migraine
The purpose of the study is the measure the levels of lasmiditan in the body of children aged 6 to 17 with migraine. The study also will also examine the safety and tolerability of lasmiditan in children aged 6 to 17 with…
- Trial name
- NCT03988088
- Testing
- Lasmiditan
- Where
- 11 sites in United States, Japan and 1 more
- Volunteers
- 18 people
- Sponsor
- Eli Lilly and Company
Chronic Migraine
Comparison Between Transcranial Stimulation Protocols With Continuous Current in the Chronic Migraine
This study aims to compare the effects of transcranial direct current stimulation on the clinical and cognitive function in patients with chronic migraine.
- Trial name
- NEUROMIG (NCT03414203)
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- Federal University of Paraíba
Headache, Migraine
The Diameter of the Middle Cerebral Artery Measured With Magnetic Resonance Angiography
To examine the ability of MRA to measure the effect of GTN on the intra-cranial vascular response during the GTN-induced headache in healthy volunteers.
- Conditions
- Headache, Migraine, MR-Angiography, Healthy Volunteers
- Trial name
- NCT00256802
- Testing
- MR-angiography, GTN
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine, Neuropathic Pain
Feasibility and Effectiveness of a Specific App to Delivery Mindfulness Sessions
A standardized behavioural approach based on mindfulness delivered mainly by a specific APP on android will be developed and applied for patients with chronic pain conditions, as migraine and neuropathic pain.
- Trial name
- BE_BI_MIND_APP (NCT05101837)
- Testing
- Home program
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Chronic Migraine
Double-blind Randomized Clinical Trial of Transcranial Magnetic Stimulation in Chronic Migraine
The purpose of this study is to determine whether active repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex is safe and effective for preventive treatment of chronic migraine, compared to…
- Trial name
- TMS-CHROMIG (NCT01496950)
- Testing
- 10Hz active rTMS
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Hospital Israelita Albert Einstein
Migraine
Omega-3 Supplementation for Pediatric Migraine
The purpose of the study is to assess the biochemical and clinical effects of omega-3 polyunsaturated fatty acid (PUFA) supplementation in youth suffering from migraine, including its effects on migraine disability, psychological…
- Trial name
- NCT06899074
- Testing
- Omega 3 Polyunsaturated Fats
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Role-expectancy on Patient Reported Outcomes
Influence of Role-expectancy on Patient Reported Outcomes Among Patients With Migraine: a Randomized Clinical Trial
This study was preregistered 2019 under https://osf.io/nczhj. Since JAMA requires a registration with ClinicalTrials.gov, we post-register the study here with the identical informations from OSF (see there) Migraine is frequently…
- Trial name
- NCT06322550
- Testing
- cover story
- Where
- Germany
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Migraine
Mechanism-based Choice of Therapy for Pain: Can Successful Prevention of Migraine be Coupled to a Psychophysical Pain Modulation Profile?
Mechanism-based choice of therapy for pain: Can successful prevention of migraine be coupled to a psychophysical pain modulation profile?
- Trial name
- NCT01161017
- Testing
- Amitriptyline, Topiramate
- Where
- Israel
- Volunteers
- 67 people
- Sponsor
- Rambam Health Care Campus
Status Migrainosus
Study of Intravenous Erenumab in Patients With Status Migrainosus
The investigators will evaluate the efficacy for use of intravenous erenumab 140mg for treatment of status migrainosus in an open-label, pilot study.
- Trial name
- NCT04920331
- Testing
- Erenumab
- Where
- United States
- Sponsor
- Mayo Clinic
Migraine Disorders
Cognitive Function and Autonomic Regulation in Patients With Migraine
Individuals with migraine have impaired cognitive function and worse autonomic function compared to individuals without migraine.
- Trial name
- NCT04272229
- Testing
- Cognition, Sympathetic Nervous System, Concentratio and Attention
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fortaleza University
Migraine
Predictive Role of MIDAS Reduction at 3 Months for Erenumab Treatment
In 2021, the Italian Medicines Agency approved reimbursement of monoclonal antibodies targeting the CGRP pathway (CGRP-mAbs) as preventive therapies for patients with high frequency and chronic migraine (CM).
- Trial name
- Ere-MIDAS (NCT05442008)
- Testing
- Erenumab 70/140 mg s.c.
- Where
- Italy
- Volunteers
- 53 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Acute Migraine
Migraine Treatment With Nerivio Migra Neurostimulation Device
This is a prospective, randomized, double-blind, sham controlled multi-center trial. Ratio between treatment and control groups will be 1:1, stratified by center and use of preventive medications.
- Trial name
- NCT03076515
- Testing
- Nerivio Migra neurostimulation
- Where
- 8 sites in United States, Israel
- Volunteers
- 120 people
- Sponsor
- Theranica
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