Clinical trials: Headache Disorder
Migraine Disorders, Medication-overuse Headache
Longitudinal Study of the Patients With Medication-overuse Headache or Migraine That Completed Baseline MRI
This is a phone interview research study for patients with migraine or medication-overuse headache (MOH) who have completed baseline MRI scans.
- Trial name
- LMMM (NCT05528081)
- Testing
- Phone interview
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Wei Dai
Chronic Cluster Headache
Efficacy, Safety and Tolerability of Low Sodium Oxybate for Nocturnal Cluster Headache Attacks
The goal of this clinical trial is to evaluate the efficacy of low sodium oxybate (LXB) (brand name Xywav) in the treatment of (nocturnal) cluster headache attacks in subjects with chronic cluster headache.
- Trial name
- SUNCET (NCT06950281)
- Testing
- Low Sodium Oxybate
- Volunteers
- 52 people
- Sponsor
- Leiden University Medical Center
Migraine
Study to Assess Function and Satisfaction of Oral Ubrogepant in Adult Participants After Multiple Migraine Attacks In Canada
Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound.
- Trial name
- NCT06692881
- Where
- 13 sites in Canada
- Volunteers
- 178 people
- Sponsor
- AbbVie
Medication Overuse Headache
Ibudilast in the Treatment of Medication Overuse Headache
The purpose of this study is to determine if ibudilast is effective in reverting patients with medication overuse headache suffering chronic daily headache back to their original episodic headache pattern.
- Trial name
- NCT01317992
- Testing
- Ibudilast
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- University of Adelaide
Food Sensitivities, Headache
NAET Screening for Food Allergy, Sensitivity and Intolerances Using IgE-Specific Antigen Test and NST- NAET®
Food allergy reactions cause various health disorders in sensitive people. These reactions may be IgE-mediated,cell-mediated, energy disturbance-mediated, or a combination of the three.
- Conditions
- Food Sensitivities, Headache, Backache, Indigestion
- Trial name
- NCT00275795
- Testing
- NAET Procedures
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nambudripad's Allergy Research Foundation
Migraine
Study of Treatment Used for Migraine Headaches (MK-0974-076)
This study will describe the reasons for triptan utilization patterns (continuation and discontinuation) in triptan-naïve participants and assess the stability of treatment utilization patterns over time according to standard…
- Trial name
- MASTER (NCT01421277)
- Testing
- Statin Therapy
- Volunteers
- 216 people
- Sponsor
- Merck Sharp & Dohme LLC
Migraine
A Study to Assess an Auto-injector Being Used to Treat a Migraine Attack
The purpose of this research study is to evaluate an investigational auto-injector system for delivering sumatriptan under the skin for a single migraine attack.
- Trial name
- NCT00510419
- Testing
- "Investigational"Auto-injector (sumatriptan succinate)
- Where
- 10 sites in United States
- Volunteers
- 73 people
- Sponsor
- Pfizer
Migraine
Comparison of Efficacy Between Combination of Amitriptyline-propranolol and Pizotifen for Migraine Prophylaxis.
The goal of this clinical trial is to compare efficacy and observe common adverse effects of a combination of amitriptyline-propranolol and pizotifen as prophylactic treatments for migraine.
- Trial name
- NCT06158230
- Testing
- Pizotifen, Amitriptyline-propranolol
- Where
- Bangladesh
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Traumatic Brain Injury
The Relationship Between Obesity and Chronic Headache
The relationship between obesity and the development of chronic headache after traumatic brain injury will be investigated.
- Trial name
- NCT06445595
- Testing
- patients with traumatic brain injury
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Karaman Training and Research Hospital
Migraine
Effect of Single Oral Doses of Lasmiditan When Coadministered With Single Oral Doses of Sumatriptan in Healthy Participants
This is a randomized, double-blind, three-period, cross-over study to investigate the effect of sumatriptan (Imitrex) 100 mg on the pharmacodynamics and pharmacokinetics of lasmiditan 200 mg.
- Trial name
- NCT03076970
- Testing
- lasmiditan 200 mg, Sumatriptan
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Dizziness, Nausea
Efficacy of a Transcranial Vibrating System for Mitigation of Migraine Associated Vertigo
Vertigo is among the most common symptoms associated with migraine and affects 26.5% of migraine sufferers, leading to a dramatic impact in life limiting even the most simple activities.
- Conditions
- Dizziness, Nausea, Headache, Confusion
- Trial name
- NCT03886012
- Testing
- Otoband
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Otolith Labs
Migraine in Children, Migraine
A Study in Children and Young People With Migraine to Learn What the Body Does to Eptinezumab
The purpose of the study is to investigate how the body absorbs, distributes, and get rid of eptinezumab when given directly into a vein.
- Trial name
- NCT04537429
- Testing
- Eptinezumab
- Where
- 9 sites in United States
- Volunteers
- 28 people
- Sponsor
- H. Lundbeck A/S
Headache, Headache Disorders
Responding With Evidence and Access for Childhood Headaches
This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care providers in the context of real world care, and will demonstrate the…
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT05889624
- Testing
- CBT, Amitriptyline
- Where
- 15 sites in United States
- Volunteers
- 400 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Central Nervous System Sensitization
Correlation Between Central Sensitization Inventory and Posturographic Data
To investigate the use of balance as a screening tool for Central Sensitization, a condition of the nervous system that is associated with the development and maintenance of chronic pain.
- Trial name
- NCT03058003
- Testing
- Posturography Evaluation, Central Sensitization Inventory
- Where
- 2 sites in United States, Australia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Caps Research Network
Migraine, Acute Treatment of Migraine
Nerivio Long-term Usage in Patients With Migraine
This is a post-marketing real-world evidence study investigates long-term treatment with the Remote Electrical Neuromodulation (REN) wearable Nerivio device over 3 consecutive years in patients with migraine.
- Trial name
- NCT06738056
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- Theranica
Migraine Disorders, Headache, Migraine
The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine
The purpose of this study is to determine the effects of triptans and doxycycline on neuroinflammatory markers in acute migraine.
- Conditions
- Migraine Disorders, Headache, Migraine, Migraine, Migraine Headache
- Trial name
- NCT01653522
- Testing
- Triptan, Doxycycline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Ischemic Stroke, Brain Tumor
Confounding Factors in the Detection of Intracranial Hemorrhage With the Infrascanner
The investigators prospectively want to use the Infrascanner in patients with ischemic stroke, patients with brain surgery, patients with brain tumors, patients with intracranial hemorrhage and patients with a normal CT scan of…
- Conditions
- Ischemic Stroke, Brain Tumor, Brain Surgery, Intracranial Hemorrhage
- Trial name
- NCT02809651
- Testing
- Infrascanner
- Where
- Belgium
- Volunteers
- 89 people
- Sponsor
- Ziekenhuis Oost-Limburg
Migraine
Evaluation of an Aerobic Exercise Program in Migraine Management
This trial assesses the impact of a supervised aerobic exercise program by a kinesiologist in patients with migraine. Patients can be assigned to one of two groups 1)The exercise group or 2)non-exercise group.
- Trial name
- NCT01857557
- Testing
- Aerobic exercise
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cervicogenic Headache
Impact of Adding Instrument-assisted Soft Tissue Mobilization to Mulligan Therapy in Patients With Cervicogenic Headache
this study will be conducted to investigate the impact of adding Instrument assisted soft tissue mobilization technique to mulligan therapy in patients with cervicogenic headache
- Trial name
- CGH (NCT07373912)
- Testing
- instrumeted assissted soft tissue mobilization and mulligan therapy, mulligan therapy, postural correction exercises
- Volunteers
- 60 people
- Sponsor
- Cairo University
Migraine
Acute Treatment Trial in Adult Subjects With Migraines
The purpose of the study is to evaluate the safety and efficacy of three different intranasal dose levels of zavegepant (BHV-3500), relative to placebo, in the acute treatment of moderate to severe migraine.
- Trial name
- NCT03872453
- Testing
- Zavegepant, Intranasal Aptar Pharma Unit Dose System
- Where
- 82 sites in United States
- Volunteers
- 2,154 people
- Sponsor
- Pfizer
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